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The map label for this gene is mrdB [H]

Identifier: 194334592

GI number: 194334592

Start: 1956537

End: 1957760

Strand: Reverse

Name: mrdB [H]

Synonym: Paes_1792

Alternate gene names: 194334592

Gene position: 1957760-1956537 (Counterclockwise)

Preceding gene: 194334594

Following gene: 194334590

Centisome position: 77.91

GC content: 46.24

Gene sequence:

>1224_bases
ATGAATCAATATAACACGTTGGATGGATGGTTACTCGGTTTAATGTTTGGTTTGATATTTTTAGGGCTGATGGCTATCTA
CAGTGCAAGTAACGGTGTAGGATCTGTCGATCTTTTTTATAAGCAGCTTATGTGGTTTGGTATCGGACTGATCGTCATGG
CGATGGTCTATTATCTTGATACGAATATCATTAAGGAGTATGTTGTCGTTTATTATATCATAGGGTTGATCTTTCTTGTT
CTCGTGTTACTTTTCGGTACAAAAGTCGCCGGTGCAACCAGTTGGGTCAGGATCGGTTTTATCAGTATTCAGCCGTCAGA
GATCGCAAAAGTCACGACCATTCTCATGCTGGCAAAGTACCTTGCCACTGACGATACCGATATCACATCTCCCCGTCATA
TTCTTATAGCCATCGCCATAGCTGTTGTGCCGGCAATGCTTGTTATGCTGCAGCCTGATATGGGCACAACTCTCACCTAC
CTTTCCTATCTCTTTCCGGTCATGATTATGGCAGGTTTCAATGCCTACTATCTCATGTTGTTCGGTGTTCCTGTTCTGCT
CACTGTTATCGGTTTTTTCAATATTTATCTTCTTCTCATTTTCGCTCTCTCCAGCCTTGTCGTACTCTTTCTCATCAAGC
GAAGACTCTATTTCTCACATTTTTTGGTGACAGCTCTCGGTTTAGCAGGAGGCTTATTTACTCTCAACTCCGCATCGAAA
ATTCTTCAGCCACACCAGATGAAACGTATACAAACATTTCTGGATCCGATGTCCGATCCTCTCGGTGCAGGCTACAACGC
TCTCCAGGCAAAAATCGCTATCGGCTCAGGAGGATTTTTCGGCAAAGGGTTTCTGGAGGGGACCCAGACCCAGTTACGCT
TTATACCCGCTCAGTGGACTGACTTTATTTTCTGTGTTATCGGTGAAGAGCTCGGCCTTCTCGGGGCGATCGTTCTGCTC
AGCCTCTTTCTGGCGCTTTTGCTCAGATTGCTCTGGATGGTCAGTGTCATCAAAAATAAATTCGTCGAGCTAACCCTTGT
CGGCTTCGTCTCGCTCCTCCTCGTCCATGTCATGATCAACATCGGCATGACCATCGGTCTTTTTCCCGTCATCGGCGTTC
CACTCCCATTCCTCTCCTACGGAGGATCCTCACTCCTCGGCAACATGCTCATGGTAGCCCTCGCACTCAACTTCAACCGC
AACAAACGCAATCTCGGGTATTGA

Upstream 100 bases:

>100_bases
CTCATGATATGAAGGAACAGTTTTTGGTTGCCTCGAATGAGAAAAAAACAGTGTTCCTGTCTGAACTCTCTATTTATGAT
TTAATACGGAATCAGGTGCA

Downstream 100 bases:

>100_bases
AGAGGGGAATAGTGATTGGTGAATCGTTACCCGTTATTCGTTACCAGTTTGCGCCGACAGGCGCAAACCCGTCACGTGTC
ACTTGTCACGTGTCACTGCC

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MNQYNTLDGWLLGLMFGLIFLGLMAIYSASNGVGSVDLFYKQLMWFGIGLIVMAMVYYLDTNIIKEYVVVYYIIGLIFLV
LVLLFGTKVAGATSWVRIGFISIQPSEIAKVTTILMLAKYLATDDTDITSPRHILIAIAIAVVPAMLVMLQPDMGTTLTY
LSYLFPVMIMAGFNAYYLMLFGVPVLLTVIGFFNIYLLLIFALSSLVVLFLIKRRLYFSHFLVTALGLAGGLFTLNSASK
ILQPHQMKRIQTFLDPMSDPLGAGYNALQAKIAIGSGGFFGKGFLEGTQTQLRFIPAQWTDFIFCVIGEELGLLGAIVLL
SLFLALLLRLLWMVSVIKNKFVELTLVGFVSLLLVHVMINIGMTIGLFPVIGVPLPFLSYGGSSLLGNMLMVALALNFNR
NKRNLGY

Sequences:

>Translated_407_residues
MNQYNTLDGWLLGLMFGLIFLGLMAIYSASNGVGSVDLFYKQLMWFGIGLIVMAMVYYLDTNIIKEYVVVYYIIGLIFLV
LVLLFGTKVAGATSWVRIGFISIQPSEIAKVTTILMLAKYLATDDTDITSPRHILIAIAIAVVPAMLVMLQPDMGTTLTY
LSYLFPVMIMAGFNAYYLMLFGVPVLLTVIGFFNIYLLLIFALSSLVVLFLIKRRLYFSHFLVTALGLAGGLFTLNSASK
ILQPHQMKRIQTFLDPMSDPLGAGYNALQAKIAIGSGGFFGKGFLEGTQTQLRFIPAQWTDFIFCVIGEELGLLGAIVLL
SLFLALLLRLLWMVSVIKNKFVELTLVGFVSLLLVHVMINIGMTIGLFPVIGVPLPFLSYGGSSLLGNMLMVALALNFNR
NKRNLGY
>Mature_407_residues
MNQYNTLDGWLLGLMFGLIFLGLMAIYSASNGVGSVDLFYKQLMWFGIGLIVMAMVYYLDTNIIKEYVVVYYIIGLIFLV
LVLLFGTKVAGATSWVRIGFISIQPSEIAKVTTILMLAKYLATDDTDITSPRHILIAIAIAVVPAMLVMLQPDMGTTLTY
LSYLFPVMIMAGFNAYYLMLFGVPVLLTVIGFFNIYLLLIFALSSLVVLFLIKRRLYFSHFLVTALGLAGGLFTLNSASK
ILQPHQMKRIQTFLDPMSDPLGAGYNALQAKIAIGSGGFFGKGFLEGTQTQLRFIPAQWTDFIFCVIGEELGLLGAIVLL
SLFLALLLRLLWMVSVIKNKFVELTLVGFVSLLLVHVMINIGMTIGLFPVIGVPLPFLSYGGSSLLGNMLMVALALNFNR
NKRNLGY

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=385, Percent_Identity=35.8441558441558, Blast_Score=191, Evalue=8e-50,
Organism=Escherichia coli, GI1786277, Length=391, Percent_Identity=26.8542199488491, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44929; Mature: 44929

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQYNTLDGWLLGLMFGLIFLGLMAIYSASNGVGSVDLFYKQLMWFGIGLIVMAMVYYLD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TNIIKEYVVVYYIIGLIFLVLVLLFGTKVAGATSWVRIGFISIQPSEIAKVTTILMLAKY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHH
LATDDTDITSPRHILIAIAIAVVPAMLVMLQPDMGTTLTYLSYLFPVMIMAGFNAYYLML
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
FGVPVLLTVIGFFNIYLLLIFALSSLVVLFLIKRRLYFSHFLVTALGLAGGLFTLNSASK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCHHH
ILQPHQMKRIQTFLDPMSDPLGAGYNALQAKIAIGSGGFFGKGFLEGTQTQLRFIPAQWT
HHCHHHHHHHHHHHHHCCCCCCCCHHHHHEEEEECCCCCCCCCHHCCCHHHHEEECCHHH
DFIFCVIGEELGLLGAIVLLSLFLALLLRLLWMVSVIKNKFVELTLVGFVSLLLVHVMIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGMTIGLFPVIGVPLPFLSYGGSSLLGNMLMVALALNFNRNKRNLGY
HCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNQYNTLDGWLLGLMFGLIFLGLMAIYSASNGVGSVDLFYKQLMWFGIGLIVMAMVYYLD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TNIIKEYVVVYYIIGLIFLVLVLLFGTKVAGATSWVRIGFISIQPSEIAKVTTILMLAKY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHH
LATDDTDITSPRHILIAIAIAVVPAMLVMLQPDMGTTLTYLSYLFPVMIMAGFNAYYLML
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
FGVPVLLTVIGFFNIYLLLIFALSSLVVLFLIKRRLYFSHFLVTALGLAGGLFTLNSASK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCHHH
ILQPHQMKRIQTFLDPMSDPLGAGYNALQAKIAIGSGGFFGKGFLEGTQTQLRFIPAQWT
HHCHHHHHHHHHHHHHCCCCCCCCHHHHHEEEEECCCCCCCCCHHCCCHHHHEEECCHHH
DFIFCVIGEELGLLGAIVLLSLFLALLLRLLWMVSVIKNKFVELTLVGFVSLLLVHVMIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGMTIGLFPVIGVPLPFLSYGGSSLLGNMLMVALALNFNRNKRNLGY
HCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]