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The map label for this gene is wzc [H]

Identifier: 194334575

GI number: 194334575

Start: 1933745

End: 1936156

Strand: Reverse

Name: wzc [H]

Synonym: Paes_1775

Alternate gene names: 194334575

Gene position: 1936156-1933745 (Counterclockwise)

Preceding gene: 194334576

Following gene: 194334574

Centisome position: 77.05

GC content: 55.56

Gene sequence:

>2412_bases
ATGACGAATAACGATCCCAACCAGTTTGAACAGGAAATAAACATCCAGGAACTCCTGCAGGTTCTCTGGAACAACAAGCT
TATCATCGGTGCTGTTACCGGCCTTGTGGTGATGCTTGTGCTGCTCTACCACTTTTCGGCCACACCTGAATACCGCTCGA
CTTCCATGGTTCTTATCAAGCAGGACAAGGGCGGTGCGATGGGGGAGATGATCAATCCTTTCGGGTCACTGACCGGCTTC
GACCTGCAGAACGACATCGAACTGGTCAAGTCCTTTCCGCTGGCTGAAGAGGTTGTTCGTAATCTCTACACCAAAAAGGA
TCGTGATACCCTGCAGCTCTTTGGGGAACGAAACTATGTGTCGCCGATCGGCGGCCTGTTCGGCTGGTTGAGCTTTGGCG
GCGCCGCCGAAAAAGACAGCGTCGATTACGACGTCCAGATGCGCAAATATGCTGCTGCTCTGCAGGAGCGCATCAAGGTC
GGTAACAGCCGCGACACCGATATTCTCAACGTTTCCGTCTCCAGCCCCTTCCCTGAAGAAGCAGCCCTGCTCACCAACGC
CATTTGCCAGGCCTACATGCGCAAGGATATCGAGTGGAATGCCGATCAGGCCATGTCGGTCAAAGAGTTTGTAGGTGAAC
AGCTTGCCCAGCAGCAGCGCGAGATTTCAAGCGTGGAAAACAAGCTCTCGTCCTACATGAAGAACCAGAATATCTACGAG
CTGACCGGTAACGCCGAAAAGCTGCTTGAAAAACTGGTTGAAGCCGAGTCCCGCTACAACGACGCCCAGGCGGAGTACAA
TATTCTGAAGAAGCGGCAGGATTTTCTGGTGCAGAAGCTCTCCGACGAGGAGAAGCAGATCAGCGCCAGGATCGCCAAAA
ACGTCGATCAGCAGTCCATCGACCTGAAGAGCCGCATCAAGAAGGAGGAAAAAGCCCTGATCGAGCTGGCTAACAGCACC
GGTACAGAGGACGGATCCTACATTGCAAAAAAGCAGCAGCTCGACGTGCTCAAGCAGCGCCTGCAGGAGCTCACCCGCAA
CATGATCGCCGGTGAACTCTCCTACACCAGCCGTGCGCGCCAGTTTCAGTTCGATCTTATCTCCGAACAGCTCCAGACCG
ACCTGCGCATGGCTGAGCTCGGCTATGTTGCCCAGGAGTACCTGCGAGCCAAGAACTACTACGAAAGCCAGCTCAACCGC
CTGCCGCAGAAGCAGCTCAACTACGCCCGTCTCCAGCGCGACAGGGAGGTGCTCAACAACACCTACACTTTCCTGAAAGA
GAAACTCGAAGAGTCGCGCATCAAGATCGCCTCGGAAGTCGGCAAGGTGGTCATCGTTGGCGCGGCCTATCCTGAGCTTG
CCCCTGTTGCTCCGTCGCTGAAAAAGAATCTGCTCATCGGGCTGATCCTCGGTCTTGGCCTCGGCGGCGCGCTTGTCTTT
GTGCGCGAGATGCTCGACCACTCCCTCAAGGACGACAGCTTCCTCGAAGACCACGGCTTCACCCCGCTTGCAGCCATTCC
CTTTGTGGATTCAGATGGGGGGGGGAGCATGCAGGCCTCCATGAAGAAGTCGCTCAAAGACTTTGCCAGCGTCTTCCCGT
TCTTATCCGGCAACACAGACGGCAAAAAAGATCAGCACCAGAAGAAAAACAGTTACGGCAAACCGGTCGAATCGACCCGA
AACAAGCAGCCGCTCCTCATCGCAGACAGCCTTTCGTCTGCATTCGCTGAGTCATTCCGGGATCTGCGAACGAACATCAC
TTTTTCGCAGGCCGATCGTACGCTCAAATCAATCCTTGTCACCGGTACCGAGATCAGCGAAGGAAAGTCCACGGTGTGCA
CCAATCTCGCCTTCGCCTTTGCGCTCACCGGCAAGAAAGTGCTTATCGTCGATTGCGACCTTCGCCGCCCCAGTCAGCAC
CGTAACCTCAATACCATGAGGATGCCCGGTCTCTCCGATTACCTCGCCGGGCAGGAAAAAGATATCAATGCCGTTCTGCA
GCCGACCATGCACGAGAACCTCTCCGTCCTCCCGGCCGGCAGCCAGACCCCGAGCCCGAACGAACTGCTCGGATCCAACA
AAATGACCGAACTCGTCAAAAAGCTCGAAGAAGAGTGGGACTACGTCATTCTCGACACCCCGCCAGTACTCCTGCTCAGC
GACGCAACCCTGCTCTCACGAACCGCCGACGGCATCCTGATGGTCGTCCGCATGGGCTACACCAACAAAAACCTCCTCAA
AGAGGTTCAGAAACTCGACTATCTCAAACACCGCCTCCTCGGAGTAGCCATCATCGGCCCCTCCGACAAATCCGGCTACA
GCAACTACGGCCGCTACTACGGCCGCTACGGCTACAAAGGATACTACAGCTACAAATCCTACAACGCCTACCTCGAACCG
GAGAAAGGGTGA

Upstream 100 bases:

>100_bases
GGATAACGAACAACGAACAACGGACAACGAACAACGGACAACGAATAACGAATAACGGCTAACAAATAACGAACCACGGA
TAACGGGTAACGAATAACGA

Downstream 100 bases:

>100_bases
GGAGAGGTGAATAGTGAAGGGGGAATAGTGAAGGGGGAATAGTGAAGAGTGAATAGTGATTGGTGATTGGTGATTGGTGA
TTGGTGAATAGTGAAGAGGG

Product: capsular exopolysaccharide family

Products: ADP; protein tyrosine phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 803; Mature: 802

Protein sequence:

>803_residues
MTNNDPNQFEQEINIQELLQVLWNNKLIIGAVTGLVVMLVLLYHFSATPEYRSTSMVLIKQDKGGAMGEMINPFGSLTGF
DLQNDIELVKSFPLAEEVVRNLYTKKDRDTLQLFGERNYVSPIGGLFGWLSFGGAAEKDSVDYDVQMRKYAAALQERIKV
GNSRDTDILNVSVSSPFPEEAALLTNAICQAYMRKDIEWNADQAMSVKEFVGEQLAQQQREISSVENKLSSYMKNQNIYE
LTGNAEKLLEKLVEAESRYNDAQAEYNILKKRQDFLVQKLSDEEKQISARIAKNVDQQSIDLKSRIKKEEKALIELANST
GTEDGSYIAKKQQLDVLKQRLQELTRNMIAGELSYTSRARQFQFDLISEQLQTDLRMAELGYVAQEYLRAKNYYESQLNR
LPQKQLNYARLQRDREVLNNTYTFLKEKLEESRIKIASEVGKVVIVGAAYPELAPVAPSLKKNLLIGLILGLGLGGALVF
VREMLDHSLKDDSFLEDHGFTPLAAIPFVDSDGGGSMQASMKKSLKDFASVFPFLSGNTDGKKDQHQKKNSYGKPVESTR
NKQPLLIADSLSSAFAESFRDLRTNITFSQADRTLKSILVTGTEISEGKSTVCTNLAFAFALTGKKVLIVDCDLRRPSQH
RNLNTMRMPGLSDYLAGQEKDINAVLQPTMHENLSVLPAGSQTPSPNELLGSNKMTELVKKLEEEWDYVILDTPPVLLLS
DATLLSRTADGILMVVRMGYTNKNLLKEVQKLDYLKHRLLGVAIIGPSDKSGYSNYGRYYGRYGYKGYYSYKSYNAYLEP
EKG

Sequences:

>Translated_803_residues
MTNNDPNQFEQEINIQELLQVLWNNKLIIGAVTGLVVMLVLLYHFSATPEYRSTSMVLIKQDKGGAMGEMINPFGSLTGF
DLQNDIELVKSFPLAEEVVRNLYTKKDRDTLQLFGERNYVSPIGGLFGWLSFGGAAEKDSVDYDVQMRKYAAALQERIKV
GNSRDTDILNVSVSSPFPEEAALLTNAICQAYMRKDIEWNADQAMSVKEFVGEQLAQQQREISSVENKLSSYMKNQNIYE
LTGNAEKLLEKLVEAESRYNDAQAEYNILKKRQDFLVQKLSDEEKQISARIAKNVDQQSIDLKSRIKKEEKALIELANST
GTEDGSYIAKKQQLDVLKQRLQELTRNMIAGELSYTSRARQFQFDLISEQLQTDLRMAELGYVAQEYLRAKNYYESQLNR
LPQKQLNYARLQRDREVLNNTYTFLKEKLEESRIKIASEVGKVVIVGAAYPELAPVAPSLKKNLLIGLILGLGLGGALVF
VREMLDHSLKDDSFLEDHGFTPLAAIPFVDSDGGGSMQASMKKSLKDFASVFPFLSGNTDGKKDQHQKKNSYGKPVESTR
NKQPLLIADSLSSAFAESFRDLRTNITFSQADRTLKSILVTGTEISEGKSTVCTNLAFAFALTGKKVLIVDCDLRRPSQH
RNLNTMRMPGLSDYLAGQEKDINAVLQPTMHENLSVLPAGSQTPSPNELLGSNKMTELVKKLEEEWDYVILDTPPVLLLS
DATLLSRTADGILMVVRMGYTNKNLLKEVQKLDYLKHRLLGVAIIGPSDKSGYSNYGRYYGRYGYKGYYSYKSYNAYLEP
EKG
>Mature_802_residues
TNNDPNQFEQEINIQELLQVLWNNKLIIGAVTGLVVMLVLLYHFSATPEYRSTSMVLIKQDKGGAMGEMINPFGSLTGFD
LQNDIELVKSFPLAEEVVRNLYTKKDRDTLQLFGERNYVSPIGGLFGWLSFGGAAEKDSVDYDVQMRKYAAALQERIKVG
NSRDTDILNVSVSSPFPEEAALLTNAICQAYMRKDIEWNADQAMSVKEFVGEQLAQQQREISSVENKLSSYMKNQNIYEL
TGNAEKLLEKLVEAESRYNDAQAEYNILKKRQDFLVQKLSDEEKQISARIAKNVDQQSIDLKSRIKKEEKALIELANSTG
TEDGSYIAKKQQLDVLKQRLQELTRNMIAGELSYTSRARQFQFDLISEQLQTDLRMAELGYVAQEYLRAKNYYESQLNRL
PQKQLNYARLQRDREVLNNTYTFLKEKLEESRIKIASEVGKVVIVGAAYPELAPVAPSLKKNLLIGLILGLGLGGALVFV
REMLDHSLKDDSFLEDHGFTPLAAIPFVDSDGGGSMQASMKKSLKDFASVFPFLSGNTDGKKDQHQKKNSYGKPVESTRN
KQPLLIADSLSSAFAESFRDLRTNITFSQADRTLKSILVTGTEISEGKSTVCTNLAFAFALTGKKVLIVDCDLRRPSQHR
NLNTMRMPGLSDYLAGQEKDINAVLQPTMHENLSVLPAGSQTPSPNELLGSNKMTELVKKLEEEWDYVILDTPPVLLLSD
ATLLSRTADGILMVVRMGYTNKNLLKEVQKLDYLKHRLLGVAIIGPSDKSGYSNYGRYYGRYGYKGYYSYKSYNAYLEPE
KG

Specific function: Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium [H]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the etk/wzc family [H]

Homologues:

Organism=Escherichia coli, GI87082032, Length=528, Percent_Identity=28.219696969697, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1787216, Length=358, Percent_Identity=29.8882681564246, Blast_Score=155, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR005702
- InterPro:   IPR003856 [H]

Pfam domain/function: PF01656 CbiA; PF02706 Wzz [H]

EC number: 2.7.1.112 [C]

Molecular weight: Translated: 90337; Mature: 90206

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00133 CARBOXYPEPT_ZN_2 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNNDPNQFEQEINIQELLQVLWNNKLIIGAVTGLVVMLVLLYHFSATPEYRSTSMVLIK
CCCCCHHHHHHHCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
QDKGGAMGEMINPFGSLTGFDLQNDIELVKSFPLAEEVVRNLYTKKDRDTLQLFGERNYV
ECCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHCCCCCC
SPIGGLFGWLSFGGAAEKDSVDYDVQMRKYAAALQERIKVGNSRDTDILNVSVSSPFPEE
CHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHH
AALLTNAICQAYMRKDIEWNADQAMSVKEFVGEQLAQQQREISSVENKLSSYMKNQNIYE
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LTGNAEKLLEKLVEAESRYNDAQAEYNILKKRQDFLVQKLSDEEKQISARIAKNVDQQSI
ECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHH
DLKSRIKKEEKALIELANSTGTEDGSYIAKKQQLDVLKQRLQELTRNMIAGELSYTSRAR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFQFDLISEQLQTDLRMAELGYVAQEYLRAKNYYESQLNRLPQKQLNYARLQRDREVLNN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
TYTFLKEKLEESRIKIASEVGKVVIVGAAYPELAPVAPSLKKNLLIGLILGLGLGGALVF
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
VREMLDHSLKDDSFLEDHGFTPLAAIPFVDSDGGGSMQASMKKSLKDFASVFPFLSGNTD
HHHHHHHCCCCCCCHHHCCCCCEEEECEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
GKKDQHQKKNSYGKPVESTRNKQPLLIADSLSSAFAESFRDLRTNITFSQADRTLKSILV
CCCHHHHHHCCCCCCHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TGTEISEGKSTVCTNLAFAFALTGKKVLIVDCDLRRPSQHRNLNTMRMPGLSDYLAGQEK
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHCCCCCEECCCCHHHHCCCCC
DINAVLQPTMHENLSVLPAGSQTPSPNELLGSNKMTELVKKLEEEWDYVILDTPPVLLLS
CCHHHHCCHHHCCCEEEECCCCCCCCHHHHCCHHHHHHHHHHHHCCCEEEECCCCEEEEC
DATLLSRTADGILMVVRMGYTNKNLLKEVQKLDYLKHRLLGVAIIGPSDKSGYSNYGRYY
CHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHH
GRYGYKGYYSYKSYNAYLEPEKG
HCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TNNDPNQFEQEINIQELLQVLWNNKLIIGAVTGLVVMLVLLYHFSATPEYRSTSMVLIK
CCCCHHHHHHHCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
QDKGGAMGEMINPFGSLTGFDLQNDIELVKSFPLAEEVVRNLYTKKDRDTLQLFGERNYV
ECCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHCCCCCC
SPIGGLFGWLSFGGAAEKDSVDYDVQMRKYAAALQERIKVGNSRDTDILNVSVSSPFPEE
CHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHH
AALLTNAICQAYMRKDIEWNADQAMSVKEFVGEQLAQQQREISSVENKLSSYMKNQNIYE
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LTGNAEKLLEKLVEAESRYNDAQAEYNILKKRQDFLVQKLSDEEKQISARIAKNVDQQSI
ECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHH
DLKSRIKKEEKALIELANSTGTEDGSYIAKKQQLDVLKQRLQELTRNMIAGELSYTSRAR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFQFDLISEQLQTDLRMAELGYVAQEYLRAKNYYESQLNRLPQKQLNYARLQRDREVLNN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
TYTFLKEKLEESRIKIASEVGKVVIVGAAYPELAPVAPSLKKNLLIGLILGLGLGGALVF
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
VREMLDHSLKDDSFLEDHGFTPLAAIPFVDSDGGGSMQASMKKSLKDFASVFPFLSGNTD
HHHHHHHCCCCCCCHHHCCCCCEEEECEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
GKKDQHQKKNSYGKPVESTRNKQPLLIADSLSSAFAESFRDLRTNITFSQADRTLKSILV
CCCHHHHHHCCCCCCHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TGTEISEGKSTVCTNLAFAFALTGKKVLIVDCDLRRPSQHRNLNTMRMPGLSDYLAGQEK
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHCCCCCEECCCCHHHHCCCCC
DINAVLQPTMHENLSVLPAGSQTPSPNELLGSNKMTELVKKLEEEWDYVILDTPPVLLLS
CCHHHHCCHHHCCCEEEECCCCCCCCHHHHCCHHHHHHHHHHHHCCCEEEECCCCEEEEC
DATLLSRTADGILMVVRMGYTNKNLLKEVQKLDYLKHRLLGVAIIGPSDKSGYSNYGRYY
CHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHH
GRYGYKGYYSYKSYNAYLEPEKG
HCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; a protein tyrosine [C]

Specific reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]