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The map label for this gene is pepN [H]

Identifier: 194333490

GI number: 194333490

Start: 690823

End: 693384

Strand: Reverse

Name: pepN [H]

Synonym: Paes_0653

Alternate gene names: 194333490

Gene position: 693384-690823 (Counterclockwise)

Preceding gene: 194333491

Following gene: 194333488

Centisome position: 27.59

GC content: 52.38

Gene sequence:

>2562_bases
ATGACTTTTTCCATAGACACTGAAAACATGCTCACCCGGCAAGCGGCGGAAACCCGCAGCACCCTGGTTTCCAACACCAG
CTATACCCTTGAACTCACCCTGAAAGAACATGCTGCCGAGTACAAGGGGCGCTGCCGTGTGGCGTTTGACTATCACCGTG
GCGGTACAGACCACCTCAAACTTGATTTTATCACCAGACAGATCCATTCGGTTACGCTCAATGGCAGGGCGACGGAGGAG
TATCTGAAGGGTGATTTCGCCATCTATCTCAATGAAGATCATCTGACAGAGGGCCGCAATACGCTGGAGATCACCTACAC
CAGCCTGTTCGATAATACCGGTTCGGGCTTTCATAAATTTCACGATCCCGAAGACAATGAAGAGTACATGCATACCGACT
TTGAGCCTTACGACGCGCACTGCCTGTTCCCGTGCTTCGATCAGCCCGATATCAAAGCCTCGTACCAGCTCACGGTAAAC
GGACCCTCAAAATGGACCTATATCCACAACACCCTGCCTGAGCATACCCAAACAAACGATGATGAGGTAACGATTGCGTT
CAAGCGCACGCCTCTCTTTTCCACCTACCTCTTTGCCCTGGTTGTGGGCCCTTACACCAGATGGGAAGAGCGTTACAAGC
AGATTCCGCTTGGGATTTACTGCCGAAAGTCGCTCGCGAAATACATGGATCAGGACAATATCTTTGCTATCACCAGGGAA
GCCATGGCTACCCTGGTGGACTATTTCGACTACCCCTATCCGTACGACAAGTACGACCAGGTTTTTGTCCCGGAATTCAA
TTTCGGTGCCATGGAAAATGTAGGTTGCGTCACCTTCAGCGAACACTATATCTTCCGCAATAAAAAGCTCTACAGCGAGC
ACCTGAACCGCGCCAACACCATCACCCATGAAATGGTACACATGTGGTTCGGCGACCTGGTAACCATGAAATGGTGGAAC
GACCTCTGGCTCAACGAAAGCTTTGCCGACTACCTCTCCTATTTCGCCATGTCCAAAGGCAAGCTGTTCAGTGATGCGCT
GGAACATATGTACGCCCGCAAAGAGTGGGCCTATCAGCAGGATCAGTATGCAACCACCCACCCCATAGCCGCTTCGGCCC
GCGATACCATCGAGGCCTTCAGCAATTTTGACGGCATCAGCTACTCCAAAGGCGCCTCGGTACTTCGACAGCTTCAGTAC
TATATCGGTGACGAGGCCTTCCGCGCCTCCATTGGGCACTACTTCAAACGATTCGCTGAACAGAACACCACCCTGGATGA
TTTTCTTTCAATCATGTCAGAGAACAGCGGCATCGACATTGTCGCCTGGAGCCATCAATGGCTGGAAACCACCGGCGTCA
ATACCCTCTTGAGCCGCATCAAGAACGGCAGGCTCATGATCGAGCAGCAGGGCTCGGCCAACAACAACCTCATCCGGCAG
CATGCCATCGAATTTACCGGCTACCGTCAGAGCAATGGAGCGCTCGTCGAAAATGAAACCAAAAAAATCATCATCAACGG
GAAAACCGCCGAGGCGCCGCTGAAACTCGATACCGCGTTCGTGATCCTCAATACACACGACCACGATTACGTGAAAGTAT
TTTACAGCAATGATGCTATCGCCATCGCCCGTAGGTCACTGCATACCATTGAAGACCCGTTTGCCCGGAGGCTGGTCTGG
GGAAGCCTCTGGCAGATGGTGCGCGACAATGCACTTGCCCCGACCGAGTTCATCCGGATGGGTATTGAACTGGGCCTGAA
AGAAAAGGACTTGTCGATCCTGAACAGCCATATTATCGCAAAGATCAAAGCCATCGTGTCGGTCTACCTGACTGATGACA
ACAGAGCAATCTGGATGCCGAGGCTCAACACCATGGCCCGCGAGCGCCTTGCCGAGACTGAAAACAGCGAAGAGCAACAG
ATCATCTGGTTCGGCCTCCTGCTTGAAACCGCTCTCCTCTCCGACGAGCTGGACTACCTGCACGCCCTTGTCACGGGAGC
CGAGTCCATAGCATCGCTCGTGATCGACCAGGAAAAGCGCTGGAACATCATTGCCCGTCTGATGGCCTACGGCCATGCAG
AAGCCGAAACCCTGTTCAGCAACGAAAAAGAGCTGGATAAAAGCGACCTTGGGCTGAAAAAAGCCTTTATGGTGCAAGCC
TCAAGGCCCGACAGCGCTGAAAAGGAAACCTGCTGGCAGGCTTTTACAGAACCATCATCCCGCTCCACAGATTTTCTCCG
TTACGGAATGAATGGCTTTCACTGGCGCACGCAGAAGGATATTCTGGCGCCGTATGTCGACCGGTACTTTGAAGCTGTTG
AGAAGGTCTATACCGAGCGTGATGTGCATTACACAGAAGCCTTTGGACAACTCCTCTTTCCGCACTGGGACCAAACCCGG
AAGATGCTCCACACCATTGAAGCCTTTTTGGATGAGAAAGACAAAAAAGGCGACGAGCCACCGGCATTGCTCAGAAAAAA
GCTCATCGAACAAGCCGACGACCTGAAACGAATCCTTCCGATCCTGGAAAAACAGCAGACCGAGGTGCGTTTGAAGGAGT
AG

Upstream 100 bases:

>100_bases
CTGCTCTTCTTTCTGTGGGAAAGAACAAACTTTTTCGCATACTGAAAACGACATCCAAACCTGTTAAAGGGCATCTCTAT
CAACCACCTTCATTTGCCTC

Downstream 100 bases:

>100_bases
ATATTTTTACAGGTGATGAAATATGTCACACATGGCATATTTCATCGTTTTTGTCGGCGGAGGCAAAACGGCCTCAACAC
GCAATCAGACGAAATACTTG

Product: aminopeptidase N

Products: NA

Alternate protein names: Alanine aminopeptidase; Lysyl aminopeptidase; Lys-AP [H]

Number of amino acids: Translated: 853; Mature: 852

Protein sequence:

>853_residues
MTFSIDTENMLTRQAAETRSTLVSNTSYTLELTLKEHAAEYKGRCRVAFDYHRGGTDHLKLDFITRQIHSVTLNGRATEE
YLKGDFAIYLNEDHLTEGRNTLEITYTSLFDNTGSGFHKFHDPEDNEEYMHTDFEPYDAHCLFPCFDQPDIKASYQLTVN
GPSKWTYIHNTLPEHTQTNDDEVTIAFKRTPLFSTYLFALVVGPYTRWEERYKQIPLGIYCRKSLAKYMDQDNIFAITRE
AMATLVDYFDYPYPYDKYDQVFVPEFNFGAMENVGCVTFSEHYIFRNKKLYSEHLNRANTITHEMVHMWFGDLVTMKWWN
DLWLNESFADYLSYFAMSKGKLFSDALEHMYARKEWAYQQDQYATTHPIAASARDTIEAFSNFDGISYSKGASVLRQLQY
YIGDEAFRASIGHYFKRFAEQNTTLDDFLSIMSENSGIDIVAWSHQWLETTGVNTLLSRIKNGRLMIEQQGSANNNLIRQ
HAIEFTGYRQSNGALVENETKKIIINGKTAEAPLKLDTAFVILNTHDHDYVKVFYSNDAIAIARRSLHTIEDPFARRLVW
GSLWQMVRDNALAPTEFIRMGIELGLKEKDLSILNSHIIAKIKAIVSVYLTDDNRAIWMPRLNTMARERLAETENSEEQQ
IIWFGLLLETALLSDELDYLHALVTGAESIASLVIDQEKRWNIIARLMAYGHAEAETLFSNEKELDKSDLGLKKAFMVQA
SRPDSAEKETCWQAFTEPSSRSTDFLRYGMNGFHWRTQKDILAPYVDRYFEAVEKVYTERDVHYTEAFGQLLFPHWDQTR
KMLHTIEAFLDEKDKKGDEPPALLRKKLIEQADDLKRILPILEKQQTEVRLKE

Sequences:

>Translated_853_residues
MTFSIDTENMLTRQAAETRSTLVSNTSYTLELTLKEHAAEYKGRCRVAFDYHRGGTDHLKLDFITRQIHSVTLNGRATEE
YLKGDFAIYLNEDHLTEGRNTLEITYTSLFDNTGSGFHKFHDPEDNEEYMHTDFEPYDAHCLFPCFDQPDIKASYQLTVN
GPSKWTYIHNTLPEHTQTNDDEVTIAFKRTPLFSTYLFALVVGPYTRWEERYKQIPLGIYCRKSLAKYMDQDNIFAITRE
AMATLVDYFDYPYPYDKYDQVFVPEFNFGAMENVGCVTFSEHYIFRNKKLYSEHLNRANTITHEMVHMWFGDLVTMKWWN
DLWLNESFADYLSYFAMSKGKLFSDALEHMYARKEWAYQQDQYATTHPIAASARDTIEAFSNFDGISYSKGASVLRQLQY
YIGDEAFRASIGHYFKRFAEQNTTLDDFLSIMSENSGIDIVAWSHQWLETTGVNTLLSRIKNGRLMIEQQGSANNNLIRQ
HAIEFTGYRQSNGALVENETKKIIINGKTAEAPLKLDTAFVILNTHDHDYVKVFYSNDAIAIARRSLHTIEDPFARRLVW
GSLWQMVRDNALAPTEFIRMGIELGLKEKDLSILNSHIIAKIKAIVSVYLTDDNRAIWMPRLNTMARERLAETENSEEQQ
IIWFGLLLETALLSDELDYLHALVTGAESIASLVIDQEKRWNIIARLMAYGHAEAETLFSNEKELDKSDLGLKKAFMVQA
SRPDSAEKETCWQAFTEPSSRSTDFLRYGMNGFHWRTQKDILAPYVDRYFEAVEKVYTERDVHYTEAFGQLLFPHWDQTR
KMLHTIEAFLDEKDKKGDEPPALLRKKLIEQADDLKRILPILEKQQTEVRLKE
>Mature_852_residues
TFSIDTENMLTRQAAETRSTLVSNTSYTLELTLKEHAAEYKGRCRVAFDYHRGGTDHLKLDFITRQIHSVTLNGRATEEY
LKGDFAIYLNEDHLTEGRNTLEITYTSLFDNTGSGFHKFHDPEDNEEYMHTDFEPYDAHCLFPCFDQPDIKASYQLTVNG
PSKWTYIHNTLPEHTQTNDDEVTIAFKRTPLFSTYLFALVVGPYTRWEERYKQIPLGIYCRKSLAKYMDQDNIFAITREA
MATLVDYFDYPYPYDKYDQVFVPEFNFGAMENVGCVTFSEHYIFRNKKLYSEHLNRANTITHEMVHMWFGDLVTMKWWND
LWLNESFADYLSYFAMSKGKLFSDALEHMYARKEWAYQQDQYATTHPIAASARDTIEAFSNFDGISYSKGASVLRQLQYY
IGDEAFRASIGHYFKRFAEQNTTLDDFLSIMSENSGIDIVAWSHQWLETTGVNTLLSRIKNGRLMIEQQGSANNNLIRQH
AIEFTGYRQSNGALVENETKKIIINGKTAEAPLKLDTAFVILNTHDHDYVKVFYSNDAIAIARRSLHTIEDPFARRLVWG
SLWQMVRDNALAPTEFIRMGIELGLKEKDLSILNSHIIAKIKAIVSVYLTDDNRAIWMPRLNTMARERLAETENSEEQQI
IWFGLLLETALLSDELDYLHALVTGAESIASLVIDQEKRWNIIARLMAYGHAEAETLFSNEKELDKSDLGLKKAFMVQAS
RPDSAEKETCWQAFTEPSSRSTDFLRYGMNGFHWRTQKDILAPYVDRYFEAVEKVYTERDVHYTEAFGQLLFPHWDQTRK
MLHTIEAFLDEKDKKGDEPPALLRKKLIEQADDLKRILPILEKQQTEVRLKE

Specific function: Aminopeptidase with broad substrate specificity to several peptides. Shows strong preference for leucine but cleaves also next to Arg and lysine in peptide-bond-containing substrates [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=632, Percent_Identity=27.8481012658228, Blast_Score=207, Evalue=3e-53,
Organism=Homo sapiens, GI157266300, Length=419, Percent_Identity=31.5035799522673, Blast_Score=184, Evalue=3e-46,
Organism=Homo sapiens, GI310123622, Length=371, Percent_Identity=33.9622641509434, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI61742775, Length=397, Percent_Identity=30.9823677581864, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI61742777, Length=397, Percent_Identity=30.9823677581864, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI132814467, Length=381, Percent_Identity=30.4461942257218, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI310133497, Length=400, Percent_Identity=32, Blast_Score=173, Evalue=5e-43,
Organism=Homo sapiens, GI94818901, Length=351, Percent_Identity=31.0541310541311, Blast_Score=168, Evalue=2e-41,
Organism=Homo sapiens, GI94818891, Length=351, Percent_Identity=31.0541310541311, Blast_Score=168, Evalue=2e-41,
Organism=Homo sapiens, GI7019561, Length=409, Percent_Identity=28.361858190709, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI194306629, Length=318, Percent_Identity=32.3899371069182, Blast_Score=154, Evalue=4e-37,
Organism=Homo sapiens, GI11641261, Length=318, Percent_Identity=32.3899371069182, Blast_Score=154, Evalue=4e-37,
Organism=Homo sapiens, GI194239713, Length=334, Percent_Identity=30.2395209580838, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI4505029, Length=312, Percent_Identity=28.525641025641, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI40316915, Length=343, Percent_Identity=25.6559766763848, Blast_Score=91, Evalue=4e-18,
Organism=Escherichia coli, GI1787163, Length=273, Percent_Identity=26.7399267399267, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115533276, Length=513, Percent_Identity=29.0448343079922, Blast_Score=181, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI115533278, Length=510, Percent_Identity=29.2156862745098, Blast_Score=181, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI71989076, Length=431, Percent_Identity=26.4501160092807, Blast_Score=163, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI71989071, Length=433, Percent_Identity=26.3279445727483, Blast_Score=162, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17565628, Length=421, Percent_Identity=28.978622327791, Blast_Score=158, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI71990873, Length=366, Percent_Identity=30.327868852459, Blast_Score=153, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17569221, Length=367, Percent_Identity=30.5177111716621, Blast_Score=144, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI193206928, Length=412, Percent_Identity=26.6990291262136, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI193206926, Length=412, Percent_Identity=26.6990291262136, Blast_Score=141, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI133903840, Length=330, Percent_Identity=29.0909090909091, Blast_Score=138, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17569225, Length=400, Percent_Identity=26, Blast_Score=127, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17544504, Length=430, Percent_Identity=26.2790697674419, Blast_Score=117, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71984353, Length=460, Percent_Identity=22.8260869565217, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71984339, Length=461, Percent_Identity=22.7765726681128, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71993840, Length=299, Percent_Identity=25.4180602006689, Blast_Score=88, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI9755335, Length=455, Percent_Identity=29.4505494505495, Blast_Score=203, Evalue=7e-53,
Organism=Saccharomyces cerevisiae, GI6321837, Length=475, Percent_Identity=28, Blast_Score=184, Evalue=6e-47,
Organism=Saccharomyces cerevisiae, GI6322054, Length=453, Percent_Identity=24.0618101545254, Blast_Score=117, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6324283, Length=342, Percent_Identity=23.9766081871345, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24655274, Length=553, Percent_Identity=27.3056057866184, Blast_Score=192, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24655260, Length=553, Percent_Identity=27.3056057866184, Blast_Score=192, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24655265, Length=553, Percent_Identity=27.3056057866184, Blast_Score=192, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24655268, Length=553, Percent_Identity=27.3056057866184, Blast_Score=192, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24655252, Length=553, Percent_Identity=27.3056057866184, Blast_Score=192, Evalue=8e-49,
Organism=Drosophila melanogaster, GI24655257, Length=553, Percent_Identity=27.3056057866184, Blast_Score=192, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24646518, Length=486, Percent_Identity=29.2181069958848, Blast_Score=182, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24646516, Length=469, Percent_Identity=29.637526652452, Blast_Score=182, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24646514, Length=427, Percent_Identity=29.7423887587822, Blast_Score=180, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24646510, Length=353, Percent_Identity=33.7110481586402, Blast_Score=173, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24646512, Length=353, Percent_Identity=33.7110481586402, Blast_Score=173, Evalue=4e-43,
Organism=Drosophila melanogaster, GI28571901, Length=355, Percent_Identity=32.9577464788732, Blast_Score=170, Evalue=5e-42,
Organism=Drosophila melanogaster, GI161078673, Length=355, Percent_Identity=32.9577464788732, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24651025, Length=315, Percent_Identity=31.1111111111111, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24651023, Length=315, Percent_Identity=31.1111111111111, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24651021, Length=315, Percent_Identity=31.1111111111111, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24651016, Length=289, Percent_Identity=34.2560553633218, Blast_Score=163, Evalue=5e-40,
Organism=Drosophila melanogaster, GI221379089, Length=446, Percent_Identity=29.372197309417, Blast_Score=162, Evalue=1e-39,
Organism=Drosophila melanogaster, GI45550850, Length=395, Percent_Identity=27.8481012658228, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24650973, Length=395, Percent_Identity=27.8481012658228, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI21358341, Length=394, Percent_Identity=30.4568527918782, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24648786, Length=365, Percent_Identity=30.958904109589, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24648790, Length=465, Percent_Identity=27.741935483871, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24648784, Length=326, Percent_Identity=29.4478527607362, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI28571792, Length=311, Percent_Identity=29.903536977492, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI281362221, Length=325, Percent_Identity=29.5384615384615, Blast_Score=140, Evalue=5e-33,
Organism=Drosophila melanogaster, GI221330574, Length=369, Percent_Identity=27.6422764227642, Blast_Score=134, Evalue=3e-31,
Organism=Drosophila melanogaster, GI221458256, Length=382, Percent_Identity=26.9633507853403, Blast_Score=130, Evalue=5e-30,
Organism=Drosophila melanogaster, GI281362224, Length=382, Percent_Identity=26.9633507853403, Blast_Score=129, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24641062, Length=386, Percent_Identity=23.8341968911917, Blast_Score=116, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24585062, Length=356, Percent_Identity=24.1573033707865, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24585064, Length=356, Percent_Identity=24.1573033707865, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24585066, Length=356, Percent_Identity=24.1573033707865, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45550350, Length=356, Percent_Identity=24.1573033707865, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24584504, Length=349, Percent_Identity=24.6418338108883, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641060, Length=305, Percent_Identity=24.5901639344262, Blast_Score=83, Evalue=7e-16,
Organism=Drosophila melanogaster, GI116007874, Length=393, Percent_Identity=22.3918575063613, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012778
- InterPro:   IPR001930
- InterPro:   IPR014782 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 99108; Mature: 98976

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSIDTENMLTRQAAETRSTLVSNTSYTLELTLKEHAAEYKGRCRVAFDYHRGGTDHLK
CEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHCCCEEEEEEECCCCCCCEE
LDFITRQIHSVTLNGRATEEYLKGDFAIYLNEDHLTEGRNTLEITYTSLFDNTGSGFHKF
EHHHHHHHHEEEECCCCHHHHHCCCEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCC
HDPEDNEEYMHTDFEPYDAHCLFPCFDQPDIKASYQLTVNGPSKWTYIHNTLPEHTQTND
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCC
DEVTIAFKRTPLFSTYLFALVVGPYTRWEERYKQIPLGIYCRKSLAKYMDQDNIFAITRE
CEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEHHH
AMATLVDYFDYPYPYDKYDQVFVPEFNFGAMENVGCVTFSEHYIFRNKKLYSEHLNRANT
HHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCEEEEECHHEECCCHHHHHHCCHHHH
ITHEMVHMWFGDLVTMKWWNDLWLNESFADYLSYFAMSKGKLFSDALEHMYARKEWAYQQ
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
DQYATTHPIAASARDTIEAFSNFDGISYSKGASVLRQLQYYIGDEAFRASIGHYFKRFAE
CCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
QNTTLDDFLSIMSENSGIDIVAWSHQWLETTGVNTLLSRIKNGRLMIEQQGSANNNLIRQ
CCCCHHHHHHHHCCCCCEEEEEECCHHHHHCCHHHHHHHHCCCEEEEEECCCCCCCHHHH
HAIEFTGYRQSNGALVENETKKIIINGKTAEAPLKLDTAFVILNTHDHDYVKVFYSNDAI
HHHHHCCEECCCCCEEECCCCEEEEECCCCCCCEEEEEEEEEEECCCCCEEEEEECCCCH
AIARRSLHTIEDPFARRLVWGSLWQMVRDNALAPTEFIRMGIELGLKEKDLSILNSHIIA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
KIKAIVSVYLTDDNRAIWMPRLNTMARERLAETENSEEQQIIWFGLLLETALLSDELDYL
HHHHHHEEEEECCCCEEECCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHH
HALVTGAESIASLVIDQEKRWNIIARLMAYGHAEAETLFSNEKELDKSDLGLKKAFMVQA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHCCCHHCCHHHCCCCEEEEEEC
SRPDSAEKETCWQAFTEPSSRSTDFLRYGMNGFHWRTQKDILAPYVDRYFEAVEKVYTER
CCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHC
DVHYTEAFGQLLFPHWDQTRKMLHTIEAFLDEKDKKGDEPPALLRKKLIEQADDLKRILP
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
ILEKQQTEVRLKE
HHHCCCCCCCCCC
>Mature Secondary Structure 
TFSIDTENMLTRQAAETRSTLVSNTSYTLELTLKEHAAEYKGRCRVAFDYHRGGTDHLK
EEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHCCCEEEEEEECCCCCCCEE
LDFITRQIHSVTLNGRATEEYLKGDFAIYLNEDHLTEGRNTLEITYTSLFDNTGSGFHKF
EHHHHHHHHEEEECCCCHHHHHCCCEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCC
HDPEDNEEYMHTDFEPYDAHCLFPCFDQPDIKASYQLTVNGPSKWTYIHNTLPEHTQTND
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCC
DEVTIAFKRTPLFSTYLFALVVGPYTRWEERYKQIPLGIYCRKSLAKYMDQDNIFAITRE
CEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEHHH
AMATLVDYFDYPYPYDKYDQVFVPEFNFGAMENVGCVTFSEHYIFRNKKLYSEHLNRANT
HHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCEEEEECHHEECCCHHHHHHCCHHHH
ITHEMVHMWFGDLVTMKWWNDLWLNESFADYLSYFAMSKGKLFSDALEHMYARKEWAYQQ
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
DQYATTHPIAASARDTIEAFSNFDGISYSKGASVLRQLQYYIGDEAFRASIGHYFKRFAE
CCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
QNTTLDDFLSIMSENSGIDIVAWSHQWLETTGVNTLLSRIKNGRLMIEQQGSANNNLIRQ
CCCCHHHHHHHHCCCCCEEEEEECCHHHHHCCHHHHHHHHCCCEEEEEECCCCCCCHHHH
HAIEFTGYRQSNGALVENETKKIIINGKTAEAPLKLDTAFVILNTHDHDYVKVFYSNDAI
HHHHHCCEECCCCCEEECCCCEEEEECCCCCCCEEEEEEEEEEECCCCCEEEEEECCCCH
AIARRSLHTIEDPFARRLVWGSLWQMVRDNALAPTEFIRMGIELGLKEKDLSILNSHIIA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
KIKAIVSVYLTDDNRAIWMPRLNTMARERLAETENSEEQQIIWFGLLLETALLSDELDYL
HHHHHHEEEEECCCCEEECCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHH
HALVTGAESIASLVIDQEKRWNIIARLMAYGHAEAETLFSNEKELDKSDLGLKKAFMVQA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHCCCHHCCHHHCCCCEEEEEEC
SRPDSAEKETCWQAFTEPSSRSTDFLRYGMNGFHWRTQKDILAPYVDRYFEAVEKVYTER
CCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHC
DVHYTEAFGQLLFPHWDQTRKMLHTIEAFLDEKDKKGDEPPALLRKKLIEQADDLKRILP
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
ILEKQQTEVRLKE
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7909302; 7765336 [H]