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The map label for this gene is rpe [H]

Identifier: 194333334

GI number: 194333334

Start: 528604

End: 529269

Strand: Reverse

Name: rpe [H]

Synonym: Paes_0491

Alternate gene names: 194333334

Gene position: 529269-528604 (Counterclockwise)

Preceding gene: 194333335

Following gene: 194333329

Centisome position: 21.06

GC content: 52.55

Gene sequence:

>666_bases
ATGCAAGCAAAGACGACACTTCTTGCCCCCTCGATTCTTTCTGCGGATTTCACGCAGCTCGGCAACTCGATACAGCTTGC
CGAAAAGGCCGGTGCAGACTGGCTTCACTGCGATGTCATGGACGGACATTTCGTCCCGAACATCACCTTCGGCCCATTTA
TCATTCAGGCTATCGCCAAATGCAGCTCTATGACCATCGATACGCATTTGATGATCAGCGATCCAGACCGCTACATTCCT
GACTTCATCAAAGCGGGTTCTCACCAGGTCACCGTTCACCAGGAAACCTGTCCTCACCTGCACAGAAGCGTACAGCTGAT
CAAGAGCCTCGGAGCGAAAGCCGGTGTATCGATCAATCCCGGAACCCCGATCTCGACACTTGAAGCCATTATCGGTGAGC
TGGACATGGTCCTTCTGATGTCGGTGAATCCCGGTTTCGGCGGCCAGAAATTCATACCGTCATCGGTTGAGAAGATCAAA
AAGCTTCATGAAATGCGCAACGCCATGAACCCGGATATGGTCATTGCTGTCGATGGTGGTGTAACAGTGGATAACGCGCA
GGAACTCGTCAGCGCTGGCGCCGACGCGCTTATAGCAGGAACAGCATTTTTCAAGGCTGAAAACCCGGCAGAAGCTGCCG
CACAGATTAAATCCGCTTCCAGGTAA

Upstream 100 bases:

>100_bases
CCTGGAGACTATACCTTCAATTTTGGAATTGGGGAGCCGTTTTAATATCTACCTACACAGGACAAACCGCAATTTCTCAA
TATTAAAAGCATCATTGTTC

Downstream 100 bases:

>100_bases
ACCCCTGAAGTTCCTCTCCGAGCAATCCCTCCCCGATCAGGACGGCATCGAACGATGCCTCCTGCATCATCATCACGTCA
GACGAGCGCTTCAGACCGCT

Product: Ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MQAKTTLLAPSILSADFTQLGNSIQLAEKAGADWLHCDVMDGHFVPNITFGPFIIQAIAKCSSMTIDTHLMISDPDRYIP
DFIKAGSHQVTVHQETCPHLHRSVQLIKSLGAKAGVSINPGTPISTLEAIIGELDMVLLMSVNPGFGGQKFIPSSVEKIK
KLHEMRNAMNPDMVIAVDGGVTVDNAQELVSAGADALIAGTAFFKAENPAEAAAQIKSASR

Sequences:

>Translated_221_residues
MQAKTTLLAPSILSADFTQLGNSIQLAEKAGADWLHCDVMDGHFVPNITFGPFIIQAIAKCSSMTIDTHLMISDPDRYIP
DFIKAGSHQVTVHQETCPHLHRSVQLIKSLGAKAGVSINPGTPISTLEAIIGELDMVLLMSVNPGFGGQKFIPSSVEKIK
KLHEMRNAMNPDMVIAVDGGVTVDNAQELVSAGADALIAGTAFFKAENPAEAAAQIKSASR
>Mature_221_residues
MQAKTTLLAPSILSADFTQLGNSIQLAEKAGADWLHCDVMDGHFVPNITFGPFIIQAIAKCSSMTIDTHLMISDPDRYIP
DFIKAGSHQVTVHQETCPHLHRSVQLIKSLGAKAGVSINPGTPISTLEAIIGELDMVLLMSVNPGFGGQKFIPSSVEKIK
KLHEMRNAMNPDMVIAVDGGVTVDNAQELVSAGADALIAGTAFFKAENPAEAAAQIKSASR

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=226, Percent_Identity=36.7256637168142, Blast_Score=151, Evalue=4e-37,
Organism=Homo sapiens, GI219879828, Length=226, Percent_Identity=35.3982300884956, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI24307923, Length=159, Percent_Identity=31.4465408805031, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1789788, Length=216, Percent_Identity=44.9074074074074, Blast_Score=202, Evalue=1e-53,
Organism=Escherichia coli, GI1790523, Length=220, Percent_Identity=35.4545454545455, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1790754, Length=212, Percent_Identity=33.4905660377358, Blast_Score=110, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17552948, Length=218, Percent_Identity=38.5321100917431, Blast_Score=160, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6322341, Length=225, Percent_Identity=39.5555555555556, Blast_Score=164, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24586301, Length=218, Percent_Identity=36.697247706422, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 23489; Mature: 23489

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAKTTLLAPSILSADFTQLGNSIQLAEKAGADWLHCDVMDGHFVPNITFGPFIIQAIAK
CCCCCCCCCHHHHHHHHHHCCCCEEHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHH
CSSMTIDTHLMISDPDRYIPDFIKAGSHQVTVHQETCPHLHRSVQLIKSLGAKAGVSINP
HHCCEEEEEEEECCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCEECC
GTPISTLEAIIGELDMVLLMSVNPGFGGQKFIPSSVEKIKKLHEMRNAMNPDMVIAVDGG
CCCHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCC
VTVDNAQELVSAGADALIAGTAFFKAENPAEAAAQIKSASR
EEECCHHHHHHCCCCCEEEHHHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MQAKTTLLAPSILSADFTQLGNSIQLAEKAGADWLHCDVMDGHFVPNITFGPFIIQAIAK
CCCCCCCCCHHHHHHHHHHCCCCEEHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHH
CSSMTIDTHLMISDPDRYIPDFIKAGSHQVTVHQETCPHLHRSVQLIKSLGAKAGVSINP
HHCCEEEEEEEECCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCEECC
GTPISTLEAIIGELDMVLLMSVNPGFGGQKFIPSSVEKIKKLHEMRNAMNPDMVIAVDGG
CCCHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCC
VTVDNAQELVSAGADALIAGTAFFKAENPAEAAAQIKSASR
EEECCHHHHHHCCCCCEEEHHHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]