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The map label for this gene is fabG [H]

Identifier: 194333268

GI number: 194333268

Start: 457005

End: 457748

Strand: Reverse

Name: fabG [H]

Synonym: Paes_0424

Alternate gene names: 194333268

Gene position: 457748-457005 (Counterclockwise)

Preceding gene: 194333273

Following gene: 194333267

Centisome position: 18.22

GC content: 50.13

Gene sequence:

>744_bases
ATGGCAGAACAGCAACATAAAGTCTGTTTCATGACAGGAGGTTCGGGACGGCTCGGAAAACAGATTGCCAGCGCAATGGC
CCGTGAGGGGTACGATATCTTCTTTACATGGCACTCGTCGCACGCTGAAGCCCGCAATACCCTTGAAGCGATACAAGCCA
TAAGCCCTTCTTCGGCAATGGTGTCGTGCGACATATCGAACGTCGATGAAATCAAAAAGGCTTTTGCCGAATTTCAGGCC
CGTTTCAACCGTCTTGACCTGCTTATCACCAGTGCATCGAATTTTTTCGGTACCCCGCTTCCGGATGTGACAGAACATGA
ATGGGACAGGCTGGTAGACACCAATATGAAGGGAACGTTTTTCACCATGCAGGAAGGCGCGTCAATCATGCGCAACCAGA
ACTTTGTATCGAGAATTATCACGATAACCGATATAGCCGCAGAGCTGACATGGAAAAACTTCGCCCCCTACACCGCGTCC
AAAGCTGCTGTTCAGCACCTGACGAGAGTATTCGCCAAAGTATTCGCGCCATCGATACTGGTCAACTCTATAGCCCCGGG
AACCTTCACCATAAACCCGGAATGGAACAATGGCCAGGAACTTGACGATGAACTGGCCAACAAGATACCGCTTAAACGTA
TGGGCGACCCGGAGGATATCATCAGAACCATACGTTTTCTCTCGCAAAACGACTACGTCACCGGACAGATCATCAACGTC
GATGGCGGAAGACTGCTCTCATAA

Upstream 100 bases:

>100_bases
CTGGAATAAGAGCGATTCGACACTCAACTTTTTACCTGTAACCGCCGTTTATAGAAACAGACATCAATAAAACGCAGAGA
CTCTCATCCAGCACTCATCT

Downstream 100 bases:

>100_bases
GCAGTTATTGACCGGGCGGATGAAAAACCGGATTGAGCAGATAAAAAGTTATAACCTTCATTTCATATATTCTATTCAAA
GAGAGCGTTCAAGAGACAAC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MAEQQHKVCFMTGGSGRLGKQIASAMAREGYDIFFTWHSSHAEARNTLEAIQAISPSSAMVSCDISNVDEIKKAFAEFQA
RFNRLDLLITSASNFFGTPLPDVTEHEWDRLVDTNMKGTFFTMQEGASIMRNQNFVSRIITITDIAAELTWKNFAPYTAS
KAAVQHLTRVFAKVFAPSILVNSIAPGTFTINPEWNNGQELDDELANKIPLKRMGDPEDIIRTIRFLSQNDYVTGQIINV
DGGRLLS

Sequences:

>Translated_247_residues
MAEQQHKVCFMTGGSGRLGKQIASAMAREGYDIFFTWHSSHAEARNTLEAIQAISPSSAMVSCDISNVDEIKKAFAEFQA
RFNRLDLLITSASNFFGTPLPDVTEHEWDRLVDTNMKGTFFTMQEGASIMRNQNFVSRIITITDIAAELTWKNFAPYTAS
KAAVQHLTRVFAKVFAPSILVNSIAPGTFTINPEWNNGQELDDELANKIPLKRMGDPEDIIRTIRFLSQNDYVTGQIINV
DGGRLLS
>Mature_246_residues
AEQQHKVCFMTGGSGRLGKQIASAMAREGYDIFFTWHSSHAEARNTLEAIQAISPSSAMVSCDISNVDEIKKAFAEFQAR
FNRLDLLITSASNFFGTPLPDVTEHEWDRLVDTNMKGTFFTMQEGASIMRNQNFVSRIITITDIAAELTWKNFAPYTASK
AAVQHLTRVFAKVFAPSILVNSIAPGTFTINPEWNNGQELDDELANKIPLKRMGDPEDIIRTIRFLSQNDYVTGQIINVD
GGRLLS

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=29.2181069958848, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=26.9076305220884, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=26.7206477732794, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=25.78125, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=24.1935483870968, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=25.4098360655738, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI59889578, Length=198, Percent_Identity=26.7676767676768, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4758504, Length=250, Percent_Identity=24.4, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=26, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=29.0983606557377, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=31.2, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=27.8225806451613, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=25.3061224489796, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=27.2727272727273, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=29.718875502008, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=24.4979919678715, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=25.609756097561, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=25.1937984496124, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=26.1410788381743, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787891, Length=251, Percent_Identity=25.4980079681275, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=23.8461538461538, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=242, Percent_Identity=26.8595041322314, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=27.3809523809524, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=26.5917602996255, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=262, Percent_Identity=25.5725190839695, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=25.7936507936508, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=23.5059760956175, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=271, Percent_Identity=26.5682656826568, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=25.3846153846154, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=190, Percent_Identity=25.7894736842105, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=171, Percent_Identity=27.4853801169591, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=23.5294117647059, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=25.7028112449799, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24639444, Length=242, Percent_Identity=29.3388429752066, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=27.6679841897233, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=23.7354085603113, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17737361, Length=252, Percent_Identity=24.6031746031746, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=22.8, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=24.8062015503876, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=24.1935483870968, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27544; Mature: 27412

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQQHKVCFMTGGSGRLGKQIASAMAREGYDIFFTWHSSHAEARNTLEAIQAISPSSAM
CCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCE
VSCDISNVDEIKKAFAEFQARFNRLDLLITSASNFFGTPLPDVTEHEWDRLVDTNMKGTF
EEECCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCEE
FTMQEGASIMRNQNFVSRIITITDIAAELTWKNFAPYTASKAAVQHLTRVFAKVFAPSIL
EEHHHCHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VNSIAPGTFTINPEWNNGQELDDELANKIPLKRMGDPEDIIRTIRFLSQNDYVTGQIINV
HHCCCCCEEEECCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEC
DGGRLLS
CCCEECC
>Mature Secondary Structure 
AEQQHKVCFMTGGSGRLGKQIASAMAREGYDIFFTWHSSHAEARNTLEAIQAISPSSAM
CCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCE
VSCDISNVDEIKKAFAEFQARFNRLDLLITSASNFFGTPLPDVTEHEWDRLVDTNMKGTF
EEECCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCEE
FTMQEGASIMRNQNFVSRIITITDIAAELTWKNFAPYTASKAAVQHLTRVFAKVFAPSIL
EEHHHCHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VNSIAPGTFTINPEWNNGQELDDELANKIPLKRMGDPEDIIRTIRFLSQNDYVTGQIINV
HHCCCCCEEEECCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEC
DGGRLLS
CCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA