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The map label for this gene is virA [H]

Identifier: 193213573

GI number: 193213573

Start: 2133654

End: 2135432

Strand: Direct

Name: virA [H]

Synonym: Cpar_1934

Alternate gene names: 193213573

Gene position: 2133654-2135432 (Clockwise)

Preceding gene: 193213572

Following gene: 193213574

Centisome position: 93.2

GC content: 51.04

Gene sequence:

>1779_bases
ATGATCGTGAACGAGCCATCAAATCTCTCGAAGAACAAGCGGCTGGAAAATCCAGCTCATTGTGGAACTACGATGAGGGG
GCATCACAAATGCGGATGCTGGGGCAGTATCCTTGATCGTGAAAAAATCCTGCATCACGACATGAACAGCAAGCCGCTGA
GTATTGCCGGATCACGGCGGCCCATCAATACAATCAGAACCGAAAACACGTCAACAATGGAAAACTGCGCCCTGGAATTG
CGCTCCTTGATCGAAAACATCCCGGGGACGATCTATCAAATCGACACTTCAGGTAAAACCACCCTGCTATCCCGCCCCCC
GGCTTTTCTGAAGGAGGCGTCTGCTGAGCAGTACACCAGGCATCTGTTCGATACCCTCTCGATAATACACCCTGATGATC
GGCAAATGGTAGCCGAGTCGTACAAAAAACTCAAATCAGCCCCACAATCGATCAAGATATCCTACAGGGTTGTCACACCA
GAGAACGCCATCCGCTGGCTCGAAGACCAGAAAACCTCGACATTCTCGGATAACGGAACCTTCAAAAGCATCGGAGGAAT
TCTGTTTGATATCACCGATCGAATTGCTGCTATTGAAGAAAACCGCAGATTGGAATCGCAAGTACGGAAATCGCAGCGCC
TCGAAACCATCGGCACACTTGCAGGCGGCATAGCCCACGATTTCAACAACATCCTGACCCCAATCCTCGGATATTCTGAA
ATGGGCCTTGGCAGTCTCGACGAAGATGACCCGATGTATGAGTACTTCACCGAAATCATGCAAGCTGCCGAACGCGCCCA
GAAGCTTGTTTCACAGATTCTGACTTTCAGCCGAGCACAGGACGGCAATCCTGCCCCAGTGCTTATACAAGACATCATCG
GCGAAGCGCTCAAGCTGCTCAGGCCATCTCTGCCATCGACCATCTCAATCGAACAACGCATCGATCAGGCCTGCCGGAGT
GTACTGGCCGATCCGTCGCAGATTCATCAGGTTATCATCAACCTCTGCACCAATGCGTTCCATGCCATGGAGCATACCGG
CGGCACCCTGACCATCGGCCTGAAAGAAATACTGCCTGGAGAACAGCAAGCCGCCTCGCTGCCAGATCTTCTGGAATCCG
GCTACGTCAAGCTAACGGTTTCAGATACGGGAAACGGCATAGACGAGGCAACCATGGAACGTATTTTCGAGCCCTTTTTT
ACGACCAAATCGATCGAAAAAGGCACCGGGCTCGGGCTTTCGGTCGTGCACGGTATCGTCACCGGTGCTGGCGGACAGAT
CATCGCTGAAAGCAGCCGAGGCAAAGGCTCGGCATTCCATGTCTACTTACCGGTTATCAACGAAAACAAAGCCCCCGAAC
CGCCCCAAAAACTGCAGTTCAACAAACATAATGCCAATATTCTTTTTGTTGATGACGAGCCTGCGGCAGTTCAGATGATG
ACCATTATGATGCAAAAACTTGGCTATACGATCCATGCCGAGAAATCACCCATCGAAGCGCTCAGGCGATTCCGGGAAAA
CCCGGAACAGTACGACCTGATCATTACGGACCTGACCATGCCGGAAATGACTGGCACTCAACTTGCTGAAAAACTGCACA
AGCTCATGCCATCAACCCCGATCATCCTGATGACCGGCTATGGCAAACTCATCGGTCATGAAACACCGTTAAACCATTAC
GGCATCAACCGCCTCCTCAAAAAGCCAGTCAAGCTGCATCAATTGGCATCAACAGTCCATGAAGTACTCAACGAAACCAA
CCACTGTAAAACGCAATGA

Upstream 100 bases:

>100_bases
AAGCAATAAAGGACGCTAAGATGGCCCACTGGGAGTGGGTTACGCCGGGGAAGGTCTTACCCCCATAACCATAGAACGAT
GGAAACAACAGCTCCCCCAG

Downstream 100 bases:

>100_bases
AAATACTAGTCATCGACGACGATCCATCCGTCAGAAAGTTTATCGCCACAACCCTGAAAAATGAGAACTATACAGTCACC
GAAGCGGAAAATGGCGAGGA

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: WHR virA [H]

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MIVNEPSNLSKNKRLENPAHCGTTMRGHHKCGCWGSILDREKILHHDMNSKPLSIAGSRRPINTIRTENTSTMENCALEL
RSLIENIPGTIYQIDTSGKTTLLSRPPAFLKEASAEQYTRHLFDTLSIIHPDDRQMVAESYKKLKSAPQSIKISYRVVTP
ENAIRWLEDQKTSTFSDNGTFKSIGGILFDITDRIAAIEENRRLESQVRKSQRLETIGTLAGGIAHDFNNILTPILGYSE
MGLGSLDEDDPMYEYFTEIMQAAERAQKLVSQILTFSRAQDGNPAPVLIQDIIGEALKLLRPSLPSTISIEQRIDQACRS
VLADPSQIHQVIINLCTNAFHAMEHTGGTLTIGLKEILPGEQQAASLPDLLESGYVKLTVSDTGNGIDEATMERIFEPFF
TTKSIEKGTGLGLSVVHGIVTGAGGQIIAESSRGKGSAFHVYLPVINENKAPEPPQKLQFNKHNANILFVDDEPAAVQMM
TIMMQKLGYTIHAEKSPIEALRRFRENPEQYDLIITDLTMPEMTGTQLAEKLHKLMPSTPIILMTGYGKLIGHETPLNHY
GINRLLKKPVKLHQLASTVHEVLNETNHCKTQ

Sequences:

>Translated_592_residues
MIVNEPSNLSKNKRLENPAHCGTTMRGHHKCGCWGSILDREKILHHDMNSKPLSIAGSRRPINTIRTENTSTMENCALEL
RSLIENIPGTIYQIDTSGKTTLLSRPPAFLKEASAEQYTRHLFDTLSIIHPDDRQMVAESYKKLKSAPQSIKISYRVVTP
ENAIRWLEDQKTSTFSDNGTFKSIGGILFDITDRIAAIEENRRLESQVRKSQRLETIGTLAGGIAHDFNNILTPILGYSE
MGLGSLDEDDPMYEYFTEIMQAAERAQKLVSQILTFSRAQDGNPAPVLIQDIIGEALKLLRPSLPSTISIEQRIDQACRS
VLADPSQIHQVIINLCTNAFHAMEHTGGTLTIGLKEILPGEQQAASLPDLLESGYVKLTVSDTGNGIDEATMERIFEPFF
TTKSIEKGTGLGLSVVHGIVTGAGGQIIAESSRGKGSAFHVYLPVINENKAPEPPQKLQFNKHNANILFVDDEPAAVQMM
TIMMQKLGYTIHAEKSPIEALRRFRENPEQYDLIITDLTMPEMTGTQLAEKLHKLMPSTPIILMTGYGKLIGHETPLNHY
GINRLLKKPVKLHQLASTVHEVLNETNHCKTQ
>Mature_592_residues
MIVNEPSNLSKNKRLENPAHCGTTMRGHHKCGCWGSILDREKILHHDMNSKPLSIAGSRRPINTIRTENTSTMENCALEL
RSLIENIPGTIYQIDTSGKTTLLSRPPAFLKEASAEQYTRHLFDTLSIIHPDDRQMVAESYKKLKSAPQSIKISYRVVTP
ENAIRWLEDQKTSTFSDNGTFKSIGGILFDITDRIAAIEENRRLESQVRKSQRLETIGTLAGGIAHDFNNILTPILGYSE
MGLGSLDEDDPMYEYFTEIMQAAERAQKLVSQILTFSRAQDGNPAPVLIQDIIGEALKLLRPSLPSTISIEQRIDQACRS
VLADPSQIHQVIINLCTNAFHAMEHTGGTLTIGLKEILPGEQQAASLPDLLESGYVKLTVSDTGNGIDEATMERIFEPFF
TTKSIEKGTGLGLSVVHGIVTGAGGQIIAESSRGKGSAFHVYLPVINENKAPEPPQKLQFNKHNANILFVDDEPAAVQMM
TIMMQKLGYTIHAEKSPIEALRRFRENPEQYDLIITDLTMPEMTGTQLAEKLHKLMPSTPIILMTGYGKLIGHETPLNHY
GINRLLKKPVKLHQLASTVHEVLNETNHCKTQ

Specific function: Activates virG, by phosphorylating it, in the presence of acetosyringone or hydroxysyringone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=252, Percent_Identity=30.1587301587302, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788549, Length=262, Percent_Identity=29.0076335877863, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1788713, Length=439, Percent_Identity=25.5125284738041, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI48994928, Length=550, Percent_Identity=21.2727272727273, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI87081816, Length=242, Percent_Identity=29.3388429752066, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1790300, Length=341, Percent_Identity=26.6862170087977, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786912, Length=257, Percent_Identity=28.0155642023346, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788905, Length=122, Percent_Identity=31.9672131147541, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65756; Mature: 65756

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVNEPSNLSKNKRLENPAHCGTTMRGHHKCGCWGSILDREKILHHDMNSKPLSIAGSRR
CCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCC
PINTIRTENTSTMENCALELRSLIENIPGTIYQIDTSGKTTLLSRPPAFLKEASAEQYTR
CCHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCHHHHHCCHHHHHH
HLFDTLSIIHPDDRQMVAESYKKLKSAPQSIKISYRVVTPENAIRWLEDQKTSTFSDNGT
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHCCCCCCCCCCC
FKSIGGILFDITDRIAAIEENRRLESQVRKSQRLETIGTLAGGIAHDFNNILTPILGYSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
MGLGSLDEDDPMYEYFTEIMQAAERAQKLVSQILTFSRAQDGNPAPVLIQDIIGEALKLL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
RPSLPSTISIEQRIDQACRSVLADPSQIHQVIINLCTNAFHAMEHTGGTLTIGLKEILPG
CCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHCCC
EQQAASLPDLLESGYVKLTVSDTGNGIDEATMERIFEPFFTTKSIEKGTGLGLSVVHGIV
CHHHHCCHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
TGAGGQIIAESSRGKGSAFHVYLPVINENKAPEPPQKLQFNKHNANILFVDDEPAAVQMM
HCCCCCEEEECCCCCCCEEEEEEEEECCCCCCCCHHHCEECCCCCEEEEECCCCHHHHHH
TIMMQKLGYTIHAEKSPIEALRRFRENPEQYDLIITDLTMPEMTGTQLAEKLHKLMPSTP
HHHHHHCCCEEECCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCC
IILMTGYGKLIGHETPLNHYGINRLLKKPVKLHQLASTVHEVLNETNHCKTQ
EEEEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MIVNEPSNLSKNKRLENPAHCGTTMRGHHKCGCWGSILDREKILHHDMNSKPLSIAGSRR
CCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCC
PINTIRTENTSTMENCALELRSLIENIPGTIYQIDTSGKTTLLSRPPAFLKEASAEQYTR
CCHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCHHHHHCCHHHHHH
HLFDTLSIIHPDDRQMVAESYKKLKSAPQSIKISYRVVTPENAIRWLEDQKTSTFSDNGT
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHCCCCCCCCCCC
FKSIGGILFDITDRIAAIEENRRLESQVRKSQRLETIGTLAGGIAHDFNNILTPILGYSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
MGLGSLDEDDPMYEYFTEIMQAAERAQKLVSQILTFSRAQDGNPAPVLIQDIIGEALKLL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
RPSLPSTISIEQRIDQACRSVLADPSQIHQVIINLCTNAFHAMEHTGGTLTIGLKEILPG
CCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHCCC
EQQAASLPDLLESGYVKLTVSDTGNGIDEATMERIFEPFFTTKSIEKGTGLGLSVVHGIV
CHHHHCCHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
TGAGGQIIAESSRGKGSAFHVYLPVINENKAPEPPQKLQFNKHNANILFVDDEPAAVQMM
HCCCCCEEEECCCCCCCEEEEEEEEECCCCCCCCHHHCEECCCCCEEEEECCCCHHHHHH
TIMMQKLGYTIHAEKSPIEALRRFRENPEQYDLIITDLTMPEMTGTQLAEKLHKLMPSTP
HHHHHHCCCEEECCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCC
IILMTGYGKLIGHETPLNHYGINRLLKKPVKLHQLASTVHEVLNETNHCKTQ
EEEEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2796735; 2194232; 11743193; 11743194 [H]