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The map label for this gene is idsA [H]

Identifier: 193213417

GI number: 193213417

Start: 1952005

End: 1953003

Strand: Direct

Name: idsA [H]

Synonym: Cpar_1778

Alternate gene names: 193213417

Gene position: 1952005-1953003 (Clockwise)

Preceding gene: 193213416

Following gene: 193213418

Centisome position: 85.27

GC content: 58.96

Gene sequence:

>999_bases
ATGTCTTCACCAATCACCCAAGCACAGGTTGAAACCAGATACCAGCAATACCACGCCAAAATCAACGAGGCCCTTGCTGC
ATGTTTCCCGAAACAGAGCCCGGAAACCCTCTACGCCCCGGCGCGGTACATCCTCGAAGGAAAAGGCAAGCGAATCCGCC
CGTTCCTGACCCTGCTGGCATCTGAAGCGGTCAGCGGCTCTTCGGAGAACGCCCTTGGCGTAGCCCTCGGCATCGAGGTG
CTGCACAACTTCACCCTGATGCACGACGACATCATGGATGCTGCCGACCTTCGTCACGGCCGTCCGACCGTGCACAAGCA
GTGGGATGTCAACGCGGCCATTCTCTCAGGCGACATGATGATCGCCTACGCTTACGAACTGGCGCTCAAGGCGATCAGTT
CGCGCCACGCCGAGATGATTCACATCTTCAACGATGCCAACATCACCATCTGTGAAGGTCAGGCGCTCGACATGGAGCTT
GAACAGCGTAAGGATGTCACCATCGCCGACTACCTCGACATGATCTCCAAAAAGACCGGACGCCTGATCTCGGCTGCGCT
TGAAGCGGGTGGCGTGGCCGGCAACGGCACACCGGAGCAGATCGCGGCGCTGGTCACGTTCGGCGAAAAGATCGGACGCG
CCTTCCAGATTCAGGACGACTACCTCGACATCATGGCCGGTGACGGCAAGTCGGGCAAGGTACCGGGCGGTGACGTCATC
AACGGCAAAAAGACCTGGCTGCTGCTCCGTTCGCTCGAACTAGCCGAAGGCGCTGACCGCGAACTGCTGCAATCGATCTT
CGACAACAACGGCACCTCGCCGGAGAACGTCCCTGCGGTCAAGGCGATTTTCGAACAATGCGGCGTACTGGAAGAAACCA
GAGCGAAGATCAACGAGGATACCGAGGCAGCCCTCGACGCGCTCGAAAGCCTGCCCTTCGAGGAGGGCCGCGGCTATCTG
AGAGGCTTTGCCAACATCCTCATGAAGCGCGATTTCTGA

Upstream 100 bases:

>100_bases
TCTCCGGGCAGCCATGTTCCTGACCGGTTCGGCCACCACGGCACAGCTTAAACACGCACCAATCTACCGTAAACCCTGAC
TACAGGAGACTACAGGAGTT

Downstream 100 bases:

>100_bases
ATTCTGTCCGGGGGGAACCCCTCCCCCCGGCACCTCTTCAATTCCCCTGCCCCCGACCATGACAACCACCCCTGAATCGA
ACGAAACGCTCGTCCGGATC

Product: polyprenyl synthetase

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSSPITQAQVETRYQQYHAKINEALAACFPKQSPETLYAPARYILEGKGKRIRPFLTLLASEAVSGSSENALGVALGIEV
LHNFTLMHDDIMDAADLRHGRPTVHKQWDVNAAILSGDMMIAYAYELALKAISSRHAEMIHIFNDANITICEGQALDMEL
EQRKDVTIADYLDMISKKTGRLISAALEAGGVAGNGTPEQIAALVTFGEKIGRAFQIQDDYLDIMAGDGKSGKVPGGDVI
NGKKTWLLLRSLELAEGADRELLQSIFDNNGTSPENVPAVKAIFEQCGVLEETRAKINEDTEAALDALESLPFEEGRGYL
RGFANILMKRDF

Sequences:

>Translated_332_residues
MSSPITQAQVETRYQQYHAKINEALAACFPKQSPETLYAPARYILEGKGKRIRPFLTLLASEAVSGSSENALGVALGIEV
LHNFTLMHDDIMDAADLRHGRPTVHKQWDVNAAILSGDMMIAYAYELALKAISSRHAEMIHIFNDANITICEGQALDMEL
EQRKDVTIADYLDMISKKTGRLISAALEAGGVAGNGTPEQIAALVTFGEKIGRAFQIQDDYLDIMAGDGKSGKVPGGDVI
NGKKTWLLLRSLELAEGADRELLQSIFDNNGTSPENVPAVKAIFEQCGVLEETRAKINEDTEAALDALESLPFEEGRGYL
RGFANILMKRDF
>Mature_331_residues
SSPITQAQVETRYQQYHAKINEALAACFPKQSPETLYAPARYILEGKGKRIRPFLTLLASEAVSGSSENALGVALGIEVL
HNFTLMHDDIMDAADLRHGRPTVHKQWDVNAAILSGDMMIAYAYELALKAISSRHAEMIHIFNDANITICEGQALDMELE
QRKDVTIADYLDMISKKTGRLISAALEAGGVAGNGTPEQIAALVTFGEKIGRAFQIQDDYLDIMAGDGKSGKVPGGDVIN
GKKTWLLLRSLELAEGADRELLQSIFDNNGTSPENVPAVKAIFEQCGVLEETRAKINEDTEAALDALESLPFEEGRGYLR
GFANILMKRDF

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=212, Percent_Identity=30.188679245283, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI209571582, Length=235, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI4503685, Length=235, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI4758430, Length=210, Percent_Identity=27.6190476190476, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI83700220, Length=210, Percent_Identity=27.6190476190476, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI209571584, Length=235, Percent_Identity=27.6595744680851, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789578, Length=289, Percent_Identity=32.1799307958478, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1786623, Length=227, Percent_Identity=37.4449339207048, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17505681, Length=303, Percent_Identity=23.1023102310231, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17508563, Length=279, Percent_Identity=25.4480286738351, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325188, Length=245, Percent_Identity=28.1632653061224, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6322294, Length=273, Percent_Identity=24.1758241758242, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24651612, Length=302, Percent_Identity=24.8344370860927, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17137582, Length=274, Percent_Identity=27.7372262773723, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281365769, Length=277, Percent_Identity=25.9927797833935, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24660002, Length=277, Percent_Identity=25.9927797833935, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 36303; Mature: 36172

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPITQAQVETRYQQYHAKINEALAACFPKQSPETLYAPARYILEGKGKRIRPFLTLLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
SEAVSGSSENALGVALGIEVLHNFTLMHDDIMDAADLRHGRPTVHKQWDVNAAILSGDMM
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCH
IAYAYELALKAISSRHAEMIHIFNDANITICEGQALDMELEQRKDVTIADYLDMISKKTG
HHHHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHH
RLISAALEAGGVAGNGTPEQIAALVTFGEKIGRAFQIQDDYLDIMAGDGKSGKVPGGDVI
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCCCCCCC
NGKKTWLLLRSLELAEGADRELLQSIFDNNGTSPENVPAVKAIFEQCGVLEETRAKINED
CCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCC
TEAALDALESLPFEEGRGYLRGFANILMKRDF
HHHHHHHHHHCCCHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSPITQAQVETRYQQYHAKINEALAACFPKQSPETLYAPARYILEGKGKRIRPFLTLLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
SEAVSGSSENALGVALGIEVLHNFTLMHDDIMDAADLRHGRPTVHKQWDVNAAILSGDMM
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCH
IAYAYELALKAISSRHAEMIHIFNDANITICEGQALDMELEQRKDVTIADYLDMISKKTG
HHHHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHH
RLISAALEAGGVAGNGTPEQIAALVTFGEKIGRAFQIQDDYLDIMAGDGKSGKVPGGDVI
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCCCCCCC
NGKKTWLLLRSLELAEGADRELLQSIFDNNGTSPENVPAVKAIFEQCGVLEETRAKINED
CCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCCC
TEAALDALESLPFEEGRGYLRGFANILMKRDF
HHHHHHHHHHCCCHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]