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The map label for this gene is mtnA [H]

Identifier: 193213298

GI number: 193213298

Start: 1808683

End: 1809747

Strand: Direct

Name: mtnA [H]

Synonym: Cpar_1656

Alternate gene names: 193213298

Gene position: 1808683-1809747 (Clockwise)

Preceding gene: 193213297

Following gene: 193213299

Centisome position: 79.01

GC content: 60.09

Gene sequence:

>1065_bases
ATGATAGACGCTATCTCATTTAAAAACGGCACTTTCCGTTACCTCGACCAGCGCTTCCTGCCCCTGCAGGAGATCCATGT
TGAAACGAAGGATCACCAGGAAGCCATCGAAGCCATCAAAACCCTCGCCGTGCGCGGCGCTCCGCTTATCGGCGCTTCGG
CAGGCTACACGGTCGTGCTCGGCATCAACGAATACACGGGCGACAAGGCAGGCTTCCCGGCCTATTTCGAGAAGCTGATC
GCCGATGTGAACGCTTCGCGCCCGACCGCCGTAAACCTCTTCTTCGCCACGAAAAAAATGCAGGAGGTTTATGACGCCAA
CTTCGAGAACGATTCGCTCGAAACGCTCTTCGCGAAGATGACCGACATGGCGCACAAAATCTACAACGACGAAGTCGACA
ACTGCGACAAGATCGCGCGCCACGGCGTCGATCTCATCAAGCAGGATTTCGCCGAGGTGCTCAAGACCCGCAAGCTCAAC
GTACTCACCCACTGCAACACCGGCACGCTCGCCTGCTGCGGCATCGGTACGGCGCTTGGCGTCATCCGCTTGGCGTATCA
GGAAGGGCTGATCGAGCGCGTGATTTCCGCCGAGAGCCGCCCGCTCTTGCAGGGCCTGCGCCTCACCGCCTGGGAACTGG
AACATGATGGCATTCCGTTCGCCTCGATTTCCGACTCTTCGTCGGCGATTCTGATGCAGCGTGGCATGATCGACTTTGCC
GTCACCGGCGCTGACCGCATCACGGCCAACGGCGACACGGCCAACAAGATCGGTACCTTCGCCCACGCCATCAGCGCGAA
GTACCACGGGCTGCCGTTCTACATCGCGGCTCCGGTCTCGACCATCGACATCACCATGGCCGAAGGCTCGGAGATTCCGA
TCGAAGAGCGCAACGCCGACGAACTGCGCCAGATCTTCGGCACGCAGGTCGCCACCCCGACCACCCCGGTGGTGAACTAT
GCTTTCGACGTCACCCCCGGCACCCTCATCCGCGGCATCATCACCGAGAAAGAGGCCGTCGTGGGCAACTACAACGAAGG
ACTGACCAGGGTCGTCAACGGCTGA

Upstream 100 bases:

>100_bases
ATCATCGAAGTCTCCAACCGCGCCGAGCCGAACATGACCACCATTTTCAGGAACGTCGTAGCCAATCTTTAATCCTTAAC
AAGGCAATACCTGTTCTCTC

Downstream 100 bases:

>100_bases
ACCGGTCTGGACTGACAAGATCGATAGGCAACAAGGCTCCCTCACAAAGGGGGCCTTGTGCGTTTACGGCTTCAGCCACC
AGCCTGTCGCCGGGACAGAT

Product: translation initiation factor, aIF-2BI family

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MIDAISFKNGTFRYLDQRFLPLQEIHVETKDHQEAIEAIKTLAVRGAPLIGASAGYTVVLGINEYTGDKAGFPAYFEKLI
ADVNASRPTAVNLFFATKKMQEVYDANFENDSLETLFAKMTDMAHKIYNDEVDNCDKIARHGVDLIKQDFAEVLKTRKLN
VLTHCNTGTLACCGIGTALGVIRLAYQEGLIERVISAESRPLLQGLRLTAWELEHDGIPFASISDSSSAILMQRGMIDFA
VTGADRITANGDTANKIGTFAHAISAKYHGLPFYIAAPVSTIDITMAEGSEIPIEERNADELRQIFGTQVATPTTPVVNY
AFDVTPGTLIRGIITEKEAVVGNYNEGLTRVVNG

Sequences:

>Translated_354_residues
MIDAISFKNGTFRYLDQRFLPLQEIHVETKDHQEAIEAIKTLAVRGAPLIGASAGYTVVLGINEYTGDKAGFPAYFEKLI
ADVNASRPTAVNLFFATKKMQEVYDANFENDSLETLFAKMTDMAHKIYNDEVDNCDKIARHGVDLIKQDFAEVLKTRKLN
VLTHCNTGTLACCGIGTALGVIRLAYQEGLIERVISAESRPLLQGLRLTAWELEHDGIPFASISDSSSAILMQRGMIDFA
VTGADRITANGDTANKIGTFAHAISAKYHGLPFYIAAPVSTIDITMAEGSEIPIEERNADELRQIFGTQVATPTTPVVNY
AFDVTPGTLIRGIITEKEAVVGNYNEGLTRVVNG
>Mature_354_residues
MIDAISFKNGTFRYLDQRFLPLQEIHVETKDHQEAIEAIKTLAVRGAPLIGASAGYTVVLGINEYTGDKAGFPAYFEKLI
ADVNASRPTAVNLFFATKKMQEVYDANFENDSLETLFAKMTDMAHKIYNDEVDNCDKIARHGVDLIKQDFAEVLKTRKLN
VLTHCNTGTLACCGIGTALGVIRLAYQEGLIERVISAESRPLLQGLRLTAWELEHDGIPFASISDSSSAILMQRGMIDFA
VTGADRITANGDTANKIGTFAHAISAKYHGLPFYIAAPVSTIDITMAEGSEIPIEERNADELRQIFGTQVATPTTPVVNY
AFDVTPGTLIRGIITEKEAVVGNYNEGLTRVVNG

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=344, Percent_Identity=39.8255813953488, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI23943880, Length=338, Percent_Identity=34.6153846153846, Blast_Score=158, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17557462, Length=350, Percent_Identity=35.1428571428571, Blast_Score=197, Evalue=9e-51,
Organism=Saccharomyces cerevisiae, GI6325375, Length=392, Percent_Identity=31.8877551020408, Blast_Score=162, Evalue=9e-41,
Organism=Drosophila melanogaster, GI21357667, Length=344, Percent_Identity=36.046511627907, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24651647, Length=344, Percent_Identity=36.046511627907, Blast_Score=213, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 38654; Mature: 38654

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDAISFKNGTFRYLDQRFLPLQEIHVETKDHQEAIEAIKTLAVRGAPLIGASAGYTVVL
CCCCEECCCCCHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCEEECCCCCEEEE
GINEYTGDKAGFPAYFEKLIADVNASRPTAVNLFFATKKMQEVYDANFENDSLETLFAKM
ECCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHCCCCCCCHHHHHHHHH
TDMAHKIYNDEVDNCDKIARHGVDLIKQDFAEVLKTRKLNVLTHCNTGTLACCGIGTALG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHHH
VIRLAYQEGLIERVISAESRPLLQGLRLTAWELEHDGIPFASISDSSSAILMQRGMIDFA
HHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEECCCCCCEEECCCCCCCHHHHCCCEEEE
VTGADRITANGDTANKIGTFAHAISAKYHGLPFYIAAPVSTIDITMAEGSEIPIEERNAD
EECCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCCCCCCCHH
ELRQIFGTQVATPTTPVVNYAFDVTPGTLIRGIITEKEAVVGNYNEGLTRVVNG
HHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCHHHHCCCCCCHHHHCCC
>Mature Secondary Structure
MIDAISFKNGTFRYLDQRFLPLQEIHVETKDHQEAIEAIKTLAVRGAPLIGASAGYTVVL
CCCCEECCCCCHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCEEECCCCCEEEE
GINEYTGDKAGFPAYFEKLIADVNASRPTAVNLFFATKKMQEVYDANFENDSLETLFAKM
ECCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHCCCCCCCHHHHHHHHH
TDMAHKIYNDEVDNCDKIARHGVDLIKQDFAEVLKTRKLNVLTHCNTGTLACCGIGTALG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHHH
VIRLAYQEGLIERVISAESRPLLQGLRLTAWELEHDGIPFASISDSSSAILMQRGMIDFA
HHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEECCCCCCEEECCCCCCCHHHHCCCEEEE
VTGADRITANGDTANKIGTFAHAISAKYHGLPFYIAAPVSTIDITMAEGSEIPIEERNAD
EECCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCCCCCCCHH
ELRQIFGTQVATPTTPVVNYAFDVTPGTLIRGIITEKEAVVGNYNEGLTRVVNG
HHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCHHHHCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]