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The map label for this gene is argD [H]

Identifier: 193213155

GI number: 193213155

Start: 1653290

End: 1654507

Strand: Direct

Name: argD [H]

Synonym: Cpar_1510

Alternate gene names: 193213155

Gene position: 1653290-1654507 (Clockwise)

Preceding gene: 193213154

Following gene: 193213156

Centisome position: 72.22

GC content: 57.72

Gene sequence:

>1218_bases
ATGATAACCATGCACACTCCTGCAATAAATCTCGAAACCGAACAGCAGCTTTTCTTCCACAACTATGCAAGGCTGCCTCT
CGATATCGCTTACGCCAAAGGCTCATTTCTCTACACGAGTGGAGGCGACCGTTACCTCGACATGATCGCGGGCATCGGCG
TCAACGCTATCGGCTACGGCGACCAGCGCCTTGAACACGCCATCACGGAACAGGCCGCCAAATACATTCACGTCTCGAAC
CTCTTCATGCAGAAGCCGCAGTTCGACCTGGCCGCGACGTTGCTGGAGATTTCCGGGATGTCGAAGGTCTTCTTCTGCAA
CAGCGGGACCGAAGCGATCGAGGCAGCCATCAAGCTGGCGAGAAGATTCGCCGCCCGCAATGGCGACACATCGAAAACGC
AGGTGCTCTCACTAACCAACTGCTTCCACGGCAGAACCTACGGCGCGCTCTCGCTGACCGCCAAACCGAAATATGTCGGC
GGCTTCGAACCGCTCGTGCCCGAAACCGGCATGATCGATTTCAACAACATTGAGGATCTGGAACGCAAGGTCTCCAGCCG
CACGGCTGCGGTGTTTGTCGAGTTCGTGCAGGGCGAGGGCGGCATCCACAAGGTAAGCGAAGCCTTCATCGCGCGGCTGA
AAGAGCTGGCAGCGGAGCACGACTTCCTCATCGTTGCTGATGAAATCCAGGCCGGTTGCGGACGTACGGGCAGCTTCTTC
AGCTACATGCCGTTTGACATCCAGCCCGATCTGGTCTGCGTAGCCAAACCGCTCGGCGGCGGCCTGCCGCTCGGCGCGAT
CATCGGCACTGAAAAAGTTGCGGAGGTCTTCACGCCCGGCAGCCACGGCACCACTTTCGGCGGCAACCCGGTCGCCTGCG
CGGCAGGCTTGGCCATGATCGAGGCAATCAAAGCAGACAAGCTCATGGAAAACGCCATCGAAACCGGCGCGATGATGAGA
GCCGCGTTTGAAAAGATGGCTGAAAAGCATGCGCAGATTCTCGAAATCCGCCAGTACGGCCTGATGATCGGCATCACGGT
CAACCGCGAGGCCAAATATTATGTCGATGAGGCGCTGAAAAGAAACGTGCTGGTGAATGCTACCAGCCAGAACGTCATCC
GCCTGCTTCCGCCGCTGTCGATCAGCAAGGAGGAGGCGCAACTCTGTCTCGATACGCTCGATGCCATCTTCAGCGAAGAA
AAACAGGCGCAAGGCTAA

Upstream 100 bases:

>100_bases
GTCTGGCGCGCGATCCGGAGCGTGATTCGTCATCGCCAAAACCAGCAGAACGAGAACAACTGAAGCACCGTTTTACAGAT
TTGTCATCTTTCAAGAATTA

Downstream 100 bases:

>100_bases
AGCCGAAACGGCAAAGCCGCCAGCGGCTGCGAAGCCGACACCTGCCGTCATGCCGCTCGGTGCAGTGAACTACCTGTTCA
TCGCACTGGGCGCGGCAGTG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MITMHTPAINLETEQQLFFHNYARLPLDIAYAKGSFLYTSGGDRYLDMIAGIGVNAIGYGDQRLEHAITEQAAKYIHVSN
LFMQKPQFDLAATLLEISGMSKVFFCNSGTEAIEAAIKLARRFAARNGDTSKTQVLSLTNCFHGRTYGALSLTAKPKYVG
GFEPLVPETGMIDFNNIEDLERKVSSRTAAVFVEFVQGEGGIHKVSEAFIARLKELAAEHDFLIVADEIQAGCGRTGSFF
SYMPFDIQPDLVCVAKPLGGGLPLGAIIGTEKVAEVFTPGSHGTTFGGNPVACAAGLAMIEAIKADKLMENAIETGAMMR
AAFEKMAEKHAQILEIRQYGLMIGITVNREAKYYVDEALKRNVLVNATSQNVIRLLPPLSISKEEAQLCLDTLDAIFSEE
KQAQG

Sequences:

>Translated_405_residues
MITMHTPAINLETEQQLFFHNYARLPLDIAYAKGSFLYTSGGDRYLDMIAGIGVNAIGYGDQRLEHAITEQAAKYIHVSN
LFMQKPQFDLAATLLEISGMSKVFFCNSGTEAIEAAIKLARRFAARNGDTSKTQVLSLTNCFHGRTYGALSLTAKPKYVG
GFEPLVPETGMIDFNNIEDLERKVSSRTAAVFVEFVQGEGGIHKVSEAFIARLKELAAEHDFLIVADEIQAGCGRTGSFF
SYMPFDIQPDLVCVAKPLGGGLPLGAIIGTEKVAEVFTPGSHGTTFGGNPVACAAGLAMIEAIKADKLMENAIETGAMMR
AAFEKMAEKHAQILEIRQYGLMIGITVNREAKYYVDEALKRNVLVNATSQNVIRLLPPLSISKEEAQLCLDTLDAIFSEE
KQAQG
>Mature_405_residues
MITMHTPAINLETEQQLFFHNYARLPLDIAYAKGSFLYTSGGDRYLDMIAGIGVNAIGYGDQRLEHAITEQAAKYIHVSN
LFMQKPQFDLAATLLEISGMSKVFFCNSGTEAIEAAIKLARRFAARNGDTSKTQVLSLTNCFHGRTYGALSLTAKPKYVG
GFEPLVPETGMIDFNNIEDLERKVSSRTAAVFVEFVQGEGGIHKVSEAFIARLKELAAEHDFLIVADEIQAGCGRTGSFF
SYMPFDIQPDLVCVAKPLGGGLPLGAIIGTEKVAEVFTPGSHGTTFGGNPVACAAGLAMIEAIKADKLMENAIETGAMMR
AAFEKMAEKHAQILEIRQYGLMIGITVNREAKYYVDEALKRNVLVNATSQNVIRLLPPLSISKEEAQLCLDTLDAIFSEE
KQAQG

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=393, Percent_Identity=29.5165394402036, Blast_Score=188, Evalue=8e-48,
Organism=Homo sapiens, GI284507298, Length=297, Percent_Identity=31.986531986532, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI13994255, Length=440, Percent_Identity=27.2727272727273, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI226442705, Length=424, Percent_Identity=26.8867924528302, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI37574042, Length=430, Percent_Identity=26.9767441860465, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI226442709, Length=356, Percent_Identity=28.6516853932584, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI24119277, Length=432, Percent_Identity=27.3148148148148, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI188536080, Length=443, Percent_Identity=23.0248306997743, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI38679950, Length=443, Percent_Identity=23.0248306997743, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI38679946, Length=443, Percent_Identity=23.0248306997743, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1788044, Length=391, Percent_Identity=37.0843989769821, Blast_Score=271, Evalue=7e-74,
Organism=Escherichia coli, GI1789759, Length=382, Percent_Identity=33.5078534031414, Blast_Score=234, Evalue=7e-63,
Organism=Escherichia coli, GI145693181, Length=380, Percent_Identity=35.2631578947368, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1789016, Length=409, Percent_Identity=29.5843520782396, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1787560, Length=389, Percent_Identity=30.0771208226221, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1786991, Length=415, Percent_Identity=26.9879518072289, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1786349, Length=341, Percent_Identity=26.3929618768328, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25144271, Length=394, Percent_Identity=29.4416243654822, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI32564660, Length=427, Percent_Identity=28.8056206088993, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI25144274, Length=258, Percent_Identity=30.6201550387597, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=428, Percent_Identity=26.1682242990654, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17541228, Length=433, Percent_Identity=23.3256351039261, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71981843, Length=170, Percent_Identity=27.6470588235294, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324432, Length=390, Percent_Identity=32.5641025641026, Blast_Score=216, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6323470, Length=407, Percent_Identity=32.6781326781327, Blast_Score=202, Evalue=9e-53,
Organism=Saccharomyces cerevisiae, GI6324386, Length=364, Percent_Identity=27.4725274725275, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=421, Percent_Identity=23.2779097387173, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21357415, Length=380, Percent_Identity=29.7368421052632, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI161085790, Length=427, Percent_Identity=29.5081967213115, Blast_Score=181, Evalue=7e-46,
Organism=Drosophila melanogaster, GI28574759, Length=429, Percent_Identity=29.3706293706294, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI21356575, Length=415, Percent_Identity=28.6746987951807, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI281366494, Length=443, Percent_Identity=22.5733634311512, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24667139, Length=443, Percent_Identity=22.5733634311512, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24667143, Length=443, Percent_Identity=22.5733634311512, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 44080; Mature: 44080

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITMHTPAINLETEQQLFFHNYARLPLDIAYAKGSFLYTSGGDRYLDMIAGIGVNAIGYG
CEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCEEEECCCCHHHHHHHCCCCCEECCC
DQRLEHAITEQAAKYIHVSNLFMQKPQFDLAATLLEISGMSKVFFCNSGTEAIEAAIKLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHH
RRFAARNGDTSKTQVLSLTNCFHGRTYGALSLTAKPKYVGGFEPLVPETGMIDFNNIEDL
HHHHHCCCCCCHHHHEEHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHH
ERKVSSRTAAVFVEFVQGEGGIHKVSEAFIARLKELAAEHDFLIVADEIQAGCGRTGSFF
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCCCCCCC
SYMPFDIQPDLVCVAKPLGGGLPLGAIIGTEKVAEVFTPGSHGTTFGGNPVACAAGLAMI
EECCCCCCCCEEEEECCCCCCCCHHHHHCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
EAIKADKLMENAIETGAMMRAAFEKMAEKHAQILEIRQYGLMIGITVNREAKYYVDEALK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHH
RNVLVNATSQNVIRLLPPLSISKEEAQLCLDTLDAIFSEEKQAQG
CCEEEEECCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITMHTPAINLETEQQLFFHNYARLPLDIAYAKGSFLYTSGGDRYLDMIAGIGVNAIGYG
CEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCEEEECCCCHHHHHHHCCCCCEECCC
DQRLEHAITEQAAKYIHVSNLFMQKPQFDLAATLLEISGMSKVFFCNSGTEAIEAAIKLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHH
RRFAARNGDTSKTQVLSLTNCFHGRTYGALSLTAKPKYVGGFEPLVPETGMIDFNNIEDL
HHHHHCCCCCCHHHHEEHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHH
ERKVSSRTAAVFVEFVQGEGGIHKVSEAFIARLKELAAEHDFLIVADEIQAGCGRTGSFF
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCCCCCCC
SYMPFDIQPDLVCVAKPLGGGLPLGAIIGTEKVAEVFTPGSHGTTFGGNPVACAAGLAMI
EECCCCCCCCEEEEECCCCCCCCHHHHHCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
EAIKADKLMENAIETGAMMRAAFEKMAEKHAQILEIRQYGLMIGITVNREAKYYVDEALK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHH
RNVLVNATSQNVIRLLPPLSISKEEAQLCLDTLDAIFSEEKQAQG
CCEEEEECCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]