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The map label for this gene is dnaK [H]

Identifier: 193213064

GI number: 193213064

Start: 1547691

End: 1549310

Strand: Direct

Name: dnaK [H]

Synonym: Cpar_1417

Alternate gene names: 193213064

Gene position: 1547691-1549310 (Clockwise)

Preceding gene: 193213063

Following gene: 193213065

Centisome position: 67.61

GC content: 65.06

Gene sequence:

>1620_bases
ATGCCTCTTGCGTTTGATTTTGGTACCTGTAACAGCGTGGTCACTCGCTGGAACGAGGCCCTGAACGACATAGAAACTCC
CGAGCTGCCCAACCTCGGCATCCGCTACCCCCAGCCGGGCGGGGCCGATGCGCGGGTCATTCCCTCCATGATCCATTTCG
GCGATGGCGACACGCCGTTGGTCGGCAGCCAGGTTGCCGGAGCGGGATTGGCGAACCATCCGGGCACGTTCCGCTGGCTG
AAAATGGATATGCTGCGCACCGGCGGGGCCAACCGCGGGCGGCGGGTGAACGGCAGGGTGATCTACCCCCGGCTGGCGGC
GGACGATCTGGTGGATCGCATCCTGATGTTCGTGCGTGGCGCGTTCGGCGACATCGACGACGAGCTGGTGCTGACCGTGC
CGGTCGAGGCGTTCGACCACTACATCGACTGGCTGCGCGAGGCGGCGATCAAACGCTTTCCTGGCGGCATCAGCATCATC
GACGAGGCGACCGCCTGTATGCTCGGCTACAGCGAAGAAGTTCTCGACAACGAGCCGTACGGCATCGTCGATTTCGGCGG
CGGCACGCTCGACGTCTCCATCGTCCGCACCGACCTGCGGAGCGCTTCGCACGCCCGCTGCCGCATTCTCGGGCGCGCGG
GCGAAGAGATCGGCGGCATCATGATCGACAACTGGCTGCTGGAGCATATCCAGCAAGAGCAAGCGCTCAGCGACGAGGAT
ATCGCCTCCATTGGCCCGTCGCTGCTAGAAGCGGTCGAAGAGGCCAAAATCGCCCTCTCGAACGGTAGTCCGGAGGCCTC
CTTCACCCGCTTCAACGACGTGACGGGCCGGTTGATCGACGTGACGCTCACCGCCGCCACGCTGCAAGCGGTGCTCGAAA
AAAAGCGCGAGCCGGGCATGAACAACCTCTACCAGCACATCGTCCGCACGCTCGACCGCGCTCTCGATCAGGCGCGCGAC
CGGGCGGGCATCCGCAAGGAGGAGCTGAAGGGAATTTTCCTGGTCGGCGGCAGCAGCCTGCTGCCCGGCATCCAGCAAAA
AATCCGGGAGTACTTCCCCGGCACGGAGGTTCACGCAGGCCGCCCGTTCGAAGCCATTGCGCGTGGCGCGTGCCGCTTTT
CGGGCGGCGTGATCGACCAGACGCTGACGCACGACTACTGCCTGCGGAGCTGGAACCGCGAGTTGCGCGACTTCGAGCTG
GTACCGGTGGTTCCGCGCGGCACGCCCTACCCGACCGGCAAACCGGTGTGCAGCAAGTACATCAAGGCCGCCTCGGACGT
GCAGGAGGTGCTCGGGCTGGTGATTTACGAGCGCACGCTGATGAGCCGCCCGCTCATTTCCTACGTCAACGGCGCGGACG
GGCTGCGTCCGGTCAAAGAGGGCGAGCGGCTGGAGTCGCGGCACAAAGCGCTCAATCCCGAAGACAGCGAATTCATCCAT
GCCGTGCCACCATGCCGCTCGGGCGACCGCCGCTTTGTCGCCGGATTCGGAGTGGACAAGAACCGCCGCCTCACGCTCTG
GCTCCGCGACACCGAGCCGGGTAACCAGTCAACGATCCGGTTGCGCGACGGCTCCACTCTCCCACTGCCGGTGGCCGACT
TGCCGGTCGTGAAGCTTTAA

Upstream 100 bases:

>100_bases
CCGCGAAAGCGGGAACCCATGTGCTTATTCCGAATTTTGGATTCCCGCTTGCGCGGGAATGACGAGGAAACGGCATTTTA
TACCTTTGAGTAGCTAATCT

Downstream 100 bases:

>100_bases
ATTCTGGTCATTTAAACTCTTAAATAATTGCCCCGGACTTTAGTCCGGGGTGTATGGATAAAACAAAATAAATCATGGCT
TTAGCCCAATTTCTTTCTAC

Product: DnaK like protein

Products: NA

Alternate protein names: HSP70; Heat shock 70 kDa protein; Heat shock protein 70 [H]

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MPLAFDFGTCNSVVTRWNEALNDIETPELPNLGIRYPQPGGADARVIPSMIHFGDGDTPLVGSQVAGAGLANHPGTFRWL
KMDMLRTGGANRGRRVNGRVIYPRLAADDLVDRILMFVRGAFGDIDDELVLTVPVEAFDHYIDWLREAAIKRFPGGISII
DEATACMLGYSEEVLDNEPYGIVDFGGGTLDVSIVRTDLRSASHARCRILGRAGEEIGGIMIDNWLLEHIQQEQALSDED
IASIGPSLLEAVEEAKIALSNGSPEASFTRFNDVTGRLIDVTLTAATLQAVLEKKREPGMNNLYQHIVRTLDRALDQARD
RAGIRKEELKGIFLVGGSSLLPGIQQKIREYFPGTEVHAGRPFEAIARGACRFSGGVIDQTLTHDYCLRSWNRELRDFEL
VPVVPRGTPYPTGKPVCSKYIKAASDVQEVLGLVIYERTLMSRPLISYVNGADGLRPVKEGERLESRHKALNPEDSEFIH
AVPPCRSGDRRFVAGFGVDKNRRLTLWLRDTEPGNQSTIRLRDGSTLPLPVADLPVVKL

Sequences:

>Translated_539_residues
MPLAFDFGTCNSVVTRWNEALNDIETPELPNLGIRYPQPGGADARVIPSMIHFGDGDTPLVGSQVAGAGLANHPGTFRWL
KMDMLRTGGANRGRRVNGRVIYPRLAADDLVDRILMFVRGAFGDIDDELVLTVPVEAFDHYIDWLREAAIKRFPGGISII
DEATACMLGYSEEVLDNEPYGIVDFGGGTLDVSIVRTDLRSASHARCRILGRAGEEIGGIMIDNWLLEHIQQEQALSDED
IASIGPSLLEAVEEAKIALSNGSPEASFTRFNDVTGRLIDVTLTAATLQAVLEKKREPGMNNLYQHIVRTLDRALDQARD
RAGIRKEELKGIFLVGGSSLLPGIQQKIREYFPGTEVHAGRPFEAIARGACRFSGGVIDQTLTHDYCLRSWNRELRDFEL
VPVVPRGTPYPTGKPVCSKYIKAASDVQEVLGLVIYERTLMSRPLISYVNGADGLRPVKEGERLESRHKALNPEDSEFIH
AVPPCRSGDRRFVAGFGVDKNRRLTLWLRDTEPGNQSTIRLRDGSTLPLPVADLPVVKL
>Mature_538_residues
PLAFDFGTCNSVVTRWNEALNDIETPELPNLGIRYPQPGGADARVIPSMIHFGDGDTPLVGSQVAGAGLANHPGTFRWLK
MDMLRTGGANRGRRVNGRVIYPRLAADDLVDRILMFVRGAFGDIDDELVLTVPVEAFDHYIDWLREAAIKRFPGGISIID
EATACMLGYSEEVLDNEPYGIVDFGGGTLDVSIVRTDLRSASHARCRILGRAGEEIGGIMIDNWLLEHIQQEQALSDEDI
ASIGPSLLEAVEEAKIALSNGSPEASFTRFNDVTGRLIDVTLTAATLQAVLEKKREPGMNNLYQHIVRTLDRALDQARDR
AGIRKEELKGIFLVGGSSLLPGIQQKIREYFPGTEVHAGRPFEAIARGACRFSGGVIDQTLTHDYCLRSWNRELRDFELV
PVVPRGTPYPTGKPVCSKYIKAASDVQEVLGLVIYERTLMSRPLISYVNGADGLRPVKEGERLESRHKALNPEDSEFIHA
VPPCRSGDRRFVAGFGVDKNRRLTLWLRDTEPGNQSTIRLRDGSTLPLPVADLPVVKL

Specific function: Acts as a chaperone [H]

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Homo sapiens, GI16507237, Length=405, Percent_Identity=26.1728395061728, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI13676857, Length=441, Percent_Identity=24.0362811791383, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI167466173, Length=438, Percent_Identity=24.6575342465753, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI194248072, Length=438, Percent_Identity=24.6575342465753, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI124256496, Length=437, Percent_Identity=23.5697940503432, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1786196, Length=569, Percent_Identity=23.3743409490334, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788875, Length=428, Percent_Identity=23.8317757009346, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17507981, Length=412, Percent_Identity=26.6990291262136, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17534771, Length=406, Percent_Identity=26.8472906403941, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17534015, Length=409, Percent_Identity=26.4058679706601, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17534013, Length=409, Percent_Identity=26.4058679706601, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322426, Length=407, Percent_Identity=24.3243243243243, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319396, Length=410, Percent_Identity=25.609756097561, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324120, Length=428, Percent_Identity=25, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319972, Length=449, Percent_Identity=24.7216035634744, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641406, Length=403, Percent_Identity=25.8064516129032, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641408, Length=403, Percent_Identity=25.8064516129032, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641402, Length=403, Percent_Identity=25.8064516129032, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641404, Length=403, Percent_Identity=25.8064516129032, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17738165, Length=408, Percent_Identity=26.7156862745098, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571678, Length=435, Percent_Identity=24.8275862068966, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24646324, Length=438, Percent_Identity=25.1141552511416, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24646322, Length=438, Percent_Identity=25.1141552511416, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24646318, Length=438, Percent_Identity=25.1141552511416, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24647034, Length=436, Percent_Identity=25.2293577981651, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24647038, Length=436, Percent_Identity=25.2293577981651, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24647036, Length=436, Percent_Identity=25.2293577981651, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17737967, Length=436, Percent_Identity=25.2293577981651, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28571721, Length=436, Percent_Identity=25.2293577981651, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28571719, Length=436, Percent_Identity=25.2293577981651, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646137, Length=438, Percent_Identity=24.8858447488584, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24646135, Length=438, Percent_Identity=24.8858447488584, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17647515, Length=437, Percent_Identity=24.0274599542334, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24663992, Length=437, Percent_Identity=24.0274599542334, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24663988, Length=437, Percent_Identity=24.0274599542334, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737941, Length=254, Percent_Identity=29.5275590551181, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24653595, Length=317, Percent_Identity=25.2365930599369, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 320 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 500 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stati

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012725
- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 59415; Mature: 59284

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00329 HSP70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLAFDFGTCNSVVTRWNEALNDIETPELPNLGIRYPQPGGADARVIPSMIHFGDGDTPL
CCCEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
VGSQVAGAGLANHPGTFRWLKMDMLRTGGANRGRRVNGRVIYPRLAADDLVDRILMFVRG
CCCHHCCCCCCCCCCCEEHEEHHHHHCCCCCCCCEECCEEEECCHHHHHHHHHHHHHHHH
AFGDIDDELVLTVPVEAFDHYIDWLREAAIKRFPGGISIIDEATACMLGYSEEVLDNEPY
HCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCHHHHCCCCC
GIVDFGGGTLDVSIVRTDLRSASHARCRILGRAGEEIGGIMIDNWLLEHIQQEQALSDED
EEEECCCCEEEEEEEEHHHHCCCCCCEEEEECCCHHHCCCHHHHHHHHHHHHHHCCCCCH
IASIGPSLLEAVEEAKIALSNGSPEASFTRFNDVTGRLIDVTLTAATLQAVLEKKREPGM
HHHCCHHHHHHHHHHHEEECCCCCCCCHHHHHCCCCEEEEEEHHHHHHHHHHHHHCCCCH
NNLYQHIVRTLDRALDQARDRAGIRKEELKGIFLVGGSSLLPGIQQKIREYFPGTEVHAG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEEECCCHHCHHHHHHHHHHCCCCCCCCC
RPFEAIARGACRFSGGVIDQTLTHDYCLRSWNRELRDFELVPVVPRGTPYPTGKPVCSKY
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHH
IKAASDVQEVLGLVIYERTLMSRPLISYVNGADGLRPVKEGERLESRHKALNPEDSEFIH
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
AVPPCRSGDRRFVAGFGVDKNRRLTLWLRDTEPGNQSTIRLRDGSTLPLPVADLPVVKL
ECCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLAFDFGTCNSVVTRWNEALNDIETPELPNLGIRYPQPGGADARVIPSMIHFGDGDTPL
CCEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
VGSQVAGAGLANHPGTFRWLKMDMLRTGGANRGRRVNGRVIYPRLAADDLVDRILMFVRG
CCCHHCCCCCCCCCCCEEHEEHHHHHCCCCCCCCEECCEEEECCHHHHHHHHHHHHHHHH
AFGDIDDELVLTVPVEAFDHYIDWLREAAIKRFPGGISIIDEATACMLGYSEEVLDNEPY
HCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCHHHHCCCCC
GIVDFGGGTLDVSIVRTDLRSASHARCRILGRAGEEIGGIMIDNWLLEHIQQEQALSDED
EEEECCCCEEEEEEEEHHHHCCCCCCEEEEECCCHHHCCCHHHHHHHHHHHHHHCCCCCH
IASIGPSLLEAVEEAKIALSNGSPEASFTRFNDVTGRLIDVTLTAATLQAVLEKKREPGM
HHHCCHHHHHHHHHHHEEECCCCCCCCHHHHHCCCCEEEEEEHHHHHHHHHHHHHCCCCH
NNLYQHIVRTLDRALDQARDRAGIRKEELKGIFLVGGSSLLPGIQQKIREYFPGTEVHAG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEEECCCHHCHHHHHHHHHHCCCCCCCCC
RPFEAIARGACRFSGGVIDQTLTHDYCLRSWNRELRDFELVPVVPRGTPYPTGKPVCSKY
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHH
IKAASDVQEVLGLVIYERTLMSRPLISYVNGADGLRPVKEGERLESRHKALNPEDSEFIH
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
AVPPCRSGDRRFVAGFGVDKNRRLTLWLRDTEPGNQSTIRLRDGSTLPLPVADLPVVKL
ECCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA