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The map label for this gene is phr [H]

Identifier: 193213030

GI number: 193213030

Start: 1507134

End: 1508513

Strand: Direct

Name: phr [H]

Synonym: Cpar_1382

Alternate gene names: 193213030

Gene position: 1507134-1508513 (Clockwise)

Preceding gene: 193213029

Following gene: 193213031

Centisome position: 65.84

GC content: 63.19

Gene sequence:

>1380_bases
ATGGCCAAAGCAATAACAATCGACGAGCGTCGCGTGCGACACCTGAACCAGATCGAAGACCAGCACGGCACGGTCATCTA
CTGGATGTCGCGCGACCAGCGCGTGCGCCACAACTGGGCGCTGCTCTTCGCCAGCCAAAAGGCCAACCAGCTCGGCCAGC
CGCTCGAAGTGGTGTTCACCCTCGCGCCCGGCTTTCTCGGCGCGCCGATGCGCCACTACGACTTCATGTTCCGCGGACTT
CGTGAGGTGGAAACGAGACTGCGTGAGCTGGGCGTGCTGTTCACTGCGCTCTACGGCGAGCCGGGCAAAACGCTGCCGGA
GTATGCCGCCAGCCGGAACGCAGGAGCGCTCGTCGCGGACTTCTCGCCGCTGAAGCTGGTGCGCGACTGGAAGCAGGAAG
TCGCGCCAGGCCTCTCGTGCACGTTTTACGAAGTCGATGCGCACAACATCGTGCCGTGCTGGCTCGCCTCGCCAAAGCAG
GAGTACGCCGCGCGCACGATCCGCCCGAAACTCAACACCCTGCGCGAGGAGTTTCTGACAGACTTCCCCGAACCGGAACT
CCAGCATCAACCCGACAAGCTTCCGCCGCCGGTGGAGTGGGATGAGATGGAAACGCTGCTCAAGGTTGATCGCTCGGTCA
AAGCCGTACCCGCGCTGGAGCCGGGCGAAGCGGCGGCGGAATTGCACCTGCGAGACTTCGTCGATGGCCGCCTGAGCCGC
TACGCCGACGAGCGCAACGATCCAAACTCCGGCGCGGTTTCAGGCTTGTCGCCCTACCTGCACTTCGGCCAGCTTAGCGC
CCAGCACGCCGCTTTCGAGGCTGCTCGGAGCAAAGCTTCGGAAGCTAACCGCGAAGCCTTCGTCGAAGAGCTGTTCATCC
GACGGGAGCTATCGGAGAACTACTGCTACTACAACGAGCGGTACGACTCGTTCGACGGCATCCCCGAGTGGGCAAAAAAG
ACGCTGCTGGAACACACCGGCGACCGCCGCGACGCCATCTACACGCCAGAGCAGTTCGAGCAGGCGCAAACCCACGATCC
ACTCTGGAACGCCGCCCAGACGCAGTTGCTCGAAACCGGCGTCATCCACGGCTACATGCGCATGTACTGGGCCAAAAAGA
TTCTCGAATGGAGCGCCACCCCGGCGGCAGCCTTCGACATCGCGCTCATGCTCAACGATCGCTACGCCCTCGACGGACGC
GATCCCAACGGCTACGTCGGCGTCGCCTGGTCAATCGGCGGCCTCCACGACCGCCCCTGGGTCGAGCGCCCGATCTATGG
CACCATCCGCTACATGAACGCCAACGGCTGCAAAAGAAAATTCGACGTCCCCCGCTACATCGCCGAGATGAGCGGCTCGT
CGCAGGCTACACTGTTCTGA

Upstream 100 bases:

>100_bases
TCAAAGAAAGAAATTGGGCTAAAGCCCTTATTTTATATTGTTTTATCCGCATACCCCGTCCCGAAAGCTTTCGGGACGGG
GCAATTGTTTAAGAGTTTTA

Downstream 100 bases:

>100_bases
GATGGGAGGACAAATGGCAGGGTTGAAATCTTTACGCTATTTTTTTACTGTTGATGGTTAAGAATCTGCGAATGGGTAAA
CAAATCAGTAGCGAAGGTTA

Product: deoxyribodipyrimidine photolyase

Products: NA

Alternate protein names: DNA photolyase; Photoreactivating enzyme [H]

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MAKAITIDERRVRHLNQIEDQHGTVIYWMSRDQRVRHNWALLFASQKANQLGQPLEVVFTLAPGFLGAPMRHYDFMFRGL
REVETRLRELGVLFTALYGEPGKTLPEYAASRNAGALVADFSPLKLVRDWKQEVAPGLSCTFYEVDAHNIVPCWLASPKQ
EYAARTIRPKLNTLREEFLTDFPEPELQHQPDKLPPPVEWDEMETLLKVDRSVKAVPALEPGEAAAELHLRDFVDGRLSR
YADERNDPNSGAVSGLSPYLHFGQLSAQHAAFEAARSKASEANREAFVEELFIRRELSENYCYYNERYDSFDGIPEWAKK
TLLEHTGDRRDAIYTPEQFEQAQTHDPLWNAAQTQLLETGVIHGYMRMYWAKKILEWSATPAAAFDIALMLNDRYALDGR
DPNGYVGVAWSIGGLHDRPWVERPIYGTIRYMNANGCKRKFDVPRYIAEMSGSSQATLF

Sequences:

>Translated_459_residues
MAKAITIDERRVRHLNQIEDQHGTVIYWMSRDQRVRHNWALLFASQKANQLGQPLEVVFTLAPGFLGAPMRHYDFMFRGL
REVETRLRELGVLFTALYGEPGKTLPEYAASRNAGALVADFSPLKLVRDWKQEVAPGLSCTFYEVDAHNIVPCWLASPKQ
EYAARTIRPKLNTLREEFLTDFPEPELQHQPDKLPPPVEWDEMETLLKVDRSVKAVPALEPGEAAAELHLRDFVDGRLSR
YADERNDPNSGAVSGLSPYLHFGQLSAQHAAFEAARSKASEANREAFVEELFIRRELSENYCYYNERYDSFDGIPEWAKK
TLLEHTGDRRDAIYTPEQFEQAQTHDPLWNAAQTQLLETGVIHGYMRMYWAKKILEWSATPAAAFDIALMLNDRYALDGR
DPNGYVGVAWSIGGLHDRPWVERPIYGTIRYMNANGCKRKFDVPRYIAEMSGSSQATLF
>Mature_458_residues
AKAITIDERRVRHLNQIEDQHGTVIYWMSRDQRVRHNWALLFASQKANQLGQPLEVVFTLAPGFLGAPMRHYDFMFRGLR
EVETRLRELGVLFTALYGEPGKTLPEYAASRNAGALVADFSPLKLVRDWKQEVAPGLSCTFYEVDAHNIVPCWLASPKQE
YAARTIRPKLNTLREEFLTDFPEPELQHQPDKLPPPVEWDEMETLLKVDRSVKAVPALEPGEAAAELHLRDFVDGRLSRY
ADERNDPNSGAVSGLSPYLHFGQLSAQHAAFEAARSKASEANREAFVEELFIRRELSENYCYYNERYDSFDGIPEWAKKT
LLEHTGDRRDAIYTPEQFEQAQTHDPLWNAAQTQLLETGVIHGYMRMYWAKKILEWSATPAAAFDIALMLNDRYALDGRD
PNGYVGVAWSIGGLHDRPWVERPIYGTIRYMNANGCKRKFDVPRYIAEMSGSSQATLF

Specific function: Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ul

COG id: COG0415

COG function: function code L; Deoxyribodipyrimidine photolyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DNA photolyase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI24586396, Length=458, Percent_Identity=49.3449781659389, Blast_Score=457, Evalue=1e-129,
Organism=Drosophila melanogaster, GI24586398, Length=458, Percent_Identity=49.3449781659389, Blast_Score=456, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24586404, Length=155, Percent_Identity=56.1290322580645, Blast_Score=209, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008148
- InterPro:   IPR006050
- InterPro:   IPR005101
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00875 DNA_photolyase; PF03441 FAD_binding_7 [H]

EC number: =4.1.99.3 [H]

Molecular weight: Translated: 52489; Mature: 52358

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAITIDERRVRHLNQIEDQHGTVIYWMSRDQRVRHNWALLFASQKANQLGQPLEVVFT
CCCEEECCHHHHHHHHHHHHCCCCEEEEECCCCHHHCCEEEEEECHHHHHHCCHHHHHHH
LAPGFLGAPMRHYDFMFRGLREVETRLRELGVLFTALYGEPGKTLPEYAASRNAGALVAD
HCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEEEC
FSPLKLVRDWKQEVAPGLSCTFYEVDAHNIVPCWLASPKQEYAARTIRPKLNTLREEFLT
CCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
DFPEPELQHQPDKLPPPVEWDEMETLLKVDRSVKAVPALEPGEAAAELHLRDFVDGRLSR
CCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHCHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YADERNDPNSGAVSGLSPYLHFGQLSAQHAAFEAARSKASEANREAFVEELFIRRELSEN
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YCYYNERYDSFDGIPEWAKKTLLEHTGDRRDAIYTPEQFEQAQTHDPLWNAAQTQLLETG
CEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
VIHGYMRMYWAKKILEWSATPAAAFDIALMLNDRYALDGRDPNGYVGVAWSIGGLHDRPW
HHHHHHHHHHHHHHHHCCCCCHHHHEEEEEECCCEEECCCCCCCEEEEEEEECCCCCCCC
VERPIYGTIRYMNANGCKRKFDVPRYIAEMSGSSQATLF
CCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AKAITIDERRVRHLNQIEDQHGTVIYWMSRDQRVRHNWALLFASQKANQLGQPLEVVFT
CCEEECCHHHHHHHHHHHHCCCCEEEEECCCCHHHCCEEEEEECHHHHHHCCHHHHHHH
LAPGFLGAPMRHYDFMFRGLREVETRLRELGVLFTALYGEPGKTLPEYAASRNAGALVAD
HCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEEEC
FSPLKLVRDWKQEVAPGLSCTFYEVDAHNIVPCWLASPKQEYAARTIRPKLNTLREEFLT
CCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
DFPEPELQHQPDKLPPPVEWDEMETLLKVDRSVKAVPALEPGEAAAELHLRDFVDGRLSR
CCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHCHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YADERNDPNSGAVSGLSPYLHFGQLSAQHAAFEAARSKASEANREAFVEELFIRRELSEN
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YCYYNERYDSFDGIPEWAKKTLLEHTGDRRDAIYTPEQFEQAQTHDPLWNAAQTQLLETG
CEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
VIHGYMRMYWAKKILEWSATPAAAFDIALMLNDRYALDGRDPNGYVGVAWSIGGLHDRPW
HHHHHHHHHHHHHHHHCCCCCHHHHEEEEEECCCEEECCCCCCCEEEEEEEECCCCCCCC
VERPIYGTIRYMNANGCKRKFDVPRYIAEMSGSSQATLF
CCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2668276 [H]