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The map label for this gene is 193212963

Identifier: 193212963

GI number: 193212963

Start: 1425672

End: 1426196

Strand: Direct

Name: 193212963

Synonym: Cpar_1313

Alternate gene names: NA

Gene position: 1425672-1426196 (Clockwise)

Preceding gene: 193212943

Following gene: 193212964

Centisome position: 62.28

GC content: 55.62

Gene sequence:

>525_bases
ATGCAACGAATGTACTCCCCCTGGCGCGAAGTGTATATGGACTCGTTCAAGGATGAAAAACACCCGAAGCCGGAGAAAGG
CAAGTCCGTCTTCGCCGATATTCCGCCGGAGCAGGATGAAGAGCGCTACGTGCTCACTCGTGGTGAGTACTGCTTCGCCA
TTCTGAATCTCTACCCGTACAACTGCGGGCACCTGATGGTCATTCCTTACCGCCAGACTCCGGAATTCAGCGATCTTGAC
GACAAGACGATGCTTGAAATCATGCAAATCTCCGACCTCTGCATGAGAGCGCTCAAAATCACCCACAAGCCGCAGGGATT
CAACTTCGGCGCCAACCTCGGCAAGGTTGCGGGCGGCAGCGTCGATACGCACATCCACTTCCACATCGTGCCCCGCTGGG
AGGGCGACACCAACTTCATGCCGGTGCTCGGTGAAACCAAGGTGCTCTCCAACGACCTGCGCAGAACCTACGTCCAGCTC
AAAGAGGCCATCGACAAGCTCAAAAGCGAGCAGAAAGCTTCGTAA

Upstream 100 bases:

>100_bases
TCCCACCTTTGGTACGCAGTGATTGTTCAAGCCCCCTCTAAAATGTGTCATGATCCCGGCAACCCGTAAGACCGGATCAC
AAGATCAGCAGAGATTTCCC

Downstream 100 bases:

>100_bases
CCCGAGCACATGGAATCGGCCCCCTGCCCCCTCTCCGGAAACCGGGAGTTCACCCCGCTGATGCAGGTTCCCGACCGATT
CAACCTTTCCGGCAAACCGT

Product: histidine triad (HIT) protein

Products: NA

Alternate protein names: ATP adenylyltransferase; Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase; AP,A phosphorylase [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MQRMYSPWREVYMDSFKDEKHPKPEKGKSVFADIPPEQDEERYVLTRGEYCFAILNLYPYNCGHLMVIPYRQTPEFSDLD
DKTMLEIMQISDLCMRALKITHKPQGFNFGANLGKVAGGSVDTHIHFHIVPRWEGDTNFMPVLGETKVLSNDLRRTYVQL
KEAIDKLKSEQKAS

Sequences:

>Translated_174_residues
MQRMYSPWREVYMDSFKDEKHPKPEKGKSVFADIPPEQDEERYVLTRGEYCFAILNLYPYNCGHLMVIPYRQTPEFSDLD
DKTMLEIMQISDLCMRALKITHKPQGFNFGANLGKVAGGSVDTHIHFHIVPRWEGDTNFMPVLGETKVLSNDLRRTYVQL
KEAIDKLKSEQKAS
>Mature_174_residues
MQRMYSPWREVYMDSFKDEKHPKPEKGKSVFADIPPEQDEERYVLTRGEYCFAILNLYPYNCGHLMVIPYRQTPEFSDLD
DKTMLEIMQISDLCMRALKITHKPQGFNFGANLGKVAGGSVDTHIHFHIVPRWEGDTNFMPVLGETKVLSNDLRRTYVQL
KEAIDKLKSEQKAS

Specific function: Catabolizes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) into ADP and ATP. It does not catalyze the reverse phosphorolysis reaction. The optimum substrates are dinucleoside polyphosphates containing four or five phosphate residues [H]

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: =2.7.7.53 [H]

Molecular weight: Translated: 20219; Mature: 20219

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRMYSPWREVYMDSFKDEKHPKPEKGKSVFADIPPEQDEERYVLTRGEYCFAILNLYPY
CCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCEEEEEECCCC
NCGHLMVIPYRQTPEFSDLDDKTMLEIMQISDLCMRALKITHKPQGFNFGANLGKVAGGS
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
VDTHIHFHIVPRWEGDTNFMPVLGETKVLSNDLRRTYVQLKEAIDKLKSEQKAS
EEEEEEEEEEECCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQRMYSPWREVYMDSFKDEKHPKPEKGKSVFADIPPEQDEERYVLTRGEYCFAILNLYPY
CCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCEEEEEECCCC
NCGHLMVIPYRQTPEFSDLDDKTMLEIMQISDLCMRALKITHKPQGFNFGANLGKVAGGS
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
VDTHIHFHIVPRWEGDTNFMPVLGETKVLSNDLRRTYVQLKEAIDKLKSEQKAS
EEEEEEEEEEECCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]