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The map label for this gene is cfa [H]

Identifier: 193212893

GI number: 193212893

Start: 1356069

End: 1357241

Strand: Direct

Name: cfa [H]

Synonym: Cpar_1241

Alternate gene names: 193212893

Gene position: 1356069-1357241 (Clockwise)

Preceding gene: 193212891

Following gene: 193212906

Centisome position: 59.24

GC content: 56.86

Gene sequence:

>1173_bases
ATGCTTGACGACCTCTTTCGCGATCGGCTCAAAACACTTCTTGACACCGCAGGTGTAACCATCGACGGCCCCAATCCGTG
GGATGTCCGCGTGCACGATCCCCGCATGTTCAGAAAAACCGTGCTTGAGGGCAACCTCGGCTTTGGCGAGTCCTATATGG
ATGGCTGGTGGGAGTGCGACGATCTCGACGAGCTGTTTTACCGGATTCTCTCCTCCGGCATCGACCAGCAGCTTGTCACG
CTCACCAAAGCGGTCAAAACGCTCCAGAGCACGGTTCGAAACCTGCAAAAACCCGCACGAGCCTTCACAGTGGGCAAACG
GCATTACGATGCGGGCAATGACCTTTTCCTGGCTATGCTCGATCCCCTGATGCTCTACAGTTGCGCCTGCTGGAACAAGA
CCAGCGAACTCGCTCAGGCGCAGCGCAACAAGCTGACGCTGGTATTCAACAAGCTCGGCCTCGAACCGGGCATGAAGCTG
CTCGACATCGGTTGCGGCTGGGGCGGAACCGCGCGGTTTGCCGCAGAACAGTATGGAGCGAAAGTGGTCGGCATTACCGT
TTCCGAAGAACAGGCAAGCTTCGCGAGGAAGTTCTGCGCAAACCTCGATGTCGAAATCAGGCTGATGGATTACCGCAAGC
TCGAAGGCACGTTCGACCGCATCGTCTCCCTCGGCATGCTCGAACATGTGGGATATCGGAACTACCGCACCTTTTTCGAA
ACCGCCCGTCACTGCCTTCATCACGATGGGCGTCTCCTCGTGCAGAGCATTGGCAGCAATACCCCCTCAATGGCGAACGA
TCCCTGGATCGAAAAATATATCTTCCCGAACTCCCTTTTGCCCGCGGCCAGCCAGATCACCCGTGCGTATGAACGCTGCT
TTATCCTCGAAGACTGGCACTCTTTCGGCCACGACTACTCACTGACGCTCAAGGCCTGGGAAGAGAATTTCAGACGCAAC
TGGCCGCGACTTGAAAAGAACTATGATAACCGGTTCTACCGCATGTGGCGCTACTACCTGTTAAGCTGTTCGGGCGCTTT
CCGGGCGCGCGCCATCCAGCTATGGCAGATTCTGCTCAGCCCGAGCGGCATCAGGGGCAAGTGCCTGATTCCGCACGAGC
CATCCGCATCAGGGTTCAGGGATAGAGAAAGCGACCGTGGTTCTTCTCGTTGA

Upstream 100 bases:

>100_bases
CTTTTTTTAGCGTCTACACTATTTTTTGAACGGTGGTCAGTACCTTGCCGCCTTCTCTTGAAAAACGAACTGTTTTATCC
AGAGAAAGGAGCGCCTTGCC

Downstream 100 bases:

>100_bases
ATTTGCGCACCTCTTTCTGCGCAGTATGGAGAATCTTGTCGATCGGCTTCTTCCTGACAAGCATATGTCGATAGCGATCG
GTTCCGGCAAGCTTGTCGAA

Product: cyclopropane fatty acyl phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MLDDLFRDRLKTLLDTAGVTIDGPNPWDVRVHDPRMFRKTVLEGNLGFGESYMDGWWECDDLDELFYRILSSGIDQQLVT
LTKAVKTLQSTVRNLQKPARAFTVGKRHYDAGNDLFLAMLDPLMLYSCACWNKTSELAQAQRNKLTLVFNKLGLEPGMKL
LDIGCGWGGTARFAAEQYGAKVVGITVSEEQASFARKFCANLDVEIRLMDYRKLEGTFDRIVSLGMLEHVGYRNYRTFFE
TARHCLHHDGRLLVQSIGSNTPSMANDPWIEKYIFPNSLLPAASQITRAYERCFILEDWHSFGHDYSLTLKAWEENFRRN
WPRLEKNYDNRFYRMWRYYLLSCSGAFRARAIQLWQILLSPSGIRGKCLIPHEPSASGFRDRESDRGSSR

Sequences:

>Translated_390_residues
MLDDLFRDRLKTLLDTAGVTIDGPNPWDVRVHDPRMFRKTVLEGNLGFGESYMDGWWECDDLDELFYRILSSGIDQQLVT
LTKAVKTLQSTVRNLQKPARAFTVGKRHYDAGNDLFLAMLDPLMLYSCACWNKTSELAQAQRNKLTLVFNKLGLEPGMKL
LDIGCGWGGTARFAAEQYGAKVVGITVSEEQASFARKFCANLDVEIRLMDYRKLEGTFDRIVSLGMLEHVGYRNYRTFFE
TARHCLHHDGRLLVQSIGSNTPSMANDPWIEKYIFPNSLLPAASQITRAYERCFILEDWHSFGHDYSLTLKAWEENFRRN
WPRLEKNYDNRFYRMWRYYLLSCSGAFRARAIQLWQILLSPSGIRGKCLIPHEPSASGFRDRESDRGSSR
>Mature_390_residues
MLDDLFRDRLKTLLDTAGVTIDGPNPWDVRVHDPRMFRKTVLEGNLGFGESYMDGWWECDDLDELFYRILSSGIDQQLVT
LTKAVKTLQSTVRNLQKPARAFTVGKRHYDAGNDLFLAMLDPLMLYSCACWNKTSELAQAQRNKLTLVFNKLGLEPGMKL
LDIGCGWGGTARFAAEQYGAKVVGITVSEEQASFARKFCANLDVEIRLMDYRKLEGTFDRIVSLGMLEHVGYRNYRTFFE
TARHCLHHDGRLLVQSIGSNTPSMANDPWIEKYIFPNSLLPAASQITRAYERCFILEDWHSFGHDYSLTLKAWEENFRRN
WPRLEKNYDNRFYRMWRYYLLSCSGAFRARAIQLWQILLSPSGIRGKCLIPHEPSASGFRDRESDRGSSR

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=349, Percent_Identity=51.2893982808023, Blast_Score=376, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI133904226, Length=380, Percent_Identity=28.6842105263158, Blast_Score=143, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 44994; Mature: 44994

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDDLFRDRLKTLLDTAGVTIDGPNPWDVRVHDPRMFRKTVLEGNLGFGESYMDGWWECD
CCHHHHHHHHHHHHHHCCCEECCCCCCCEEECCHHHHHHHHHCCCCCCCHHHHCCCCCCC
DLDELFYRILSSGIDQQLVTLTKAVKTLQSTVRNLQKPARAFTVGKRHYDAGNDLFLAML
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHH
DPLMLYSCACWNKTSELAQAQRNKLTLVFNKLGLEPGMKLLDIGCGWGGTARFAAEQYGA
HHHHHHHHHHCCCHHHHHHHHHCCEEEEEEHHCCCCCCEEEEECCCCCCHHHHHHHHHCC
KVVGITVSEEQASFARKFCANLDVEIRLMDYRKLEGTFDRIVSLGMLEHVGYRNYRTFFE
EEEEEEECHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
TARHCLHHDGRLLVQSIGSNTPSMANDPWIEKYIFPNSLLPAASQITRAYERCFILEDWH
HHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
SFGHDYSLTLKAWEENFRRNWPRLEKNYDNRFYRMWRYYLLSCSGAFRARAIQLWQILLS
HCCCCEEEEHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
PSGIRGKCLIPHEPSASGFRDRESDRGSSR
CCCCCCEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLDDLFRDRLKTLLDTAGVTIDGPNPWDVRVHDPRMFRKTVLEGNLGFGESYMDGWWECD
CCHHHHHHHHHHHHHHCCCEECCCCCCCEEECCHHHHHHHHHCCCCCCCHHHHCCCCCCC
DLDELFYRILSSGIDQQLVTLTKAVKTLQSTVRNLQKPARAFTVGKRHYDAGNDLFLAML
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHH
DPLMLYSCACWNKTSELAQAQRNKLTLVFNKLGLEPGMKLLDIGCGWGGTARFAAEQYGA
HHHHHHHHHHCCCHHHHHHHHHCCEEEEEEHHCCCCCCEEEEECCCCCCHHHHHHHHHCC
KVVGITVSEEQASFARKFCANLDVEIRLMDYRKLEGTFDRIVSLGMLEHVGYRNYRTFFE
EEEEEEECHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
TARHCLHHDGRLLVQSIGSNTPSMANDPWIEKYIFPNSLLPAASQITRAYERCFILEDWH
HHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
SFGHDYSLTLKAWEENFRRNWPRLEKNYDNRFYRMWRYYLLSCSGAFRARAIQLWQILLS
HCCCCEEEEHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
PSGIRGKCLIPHEPSASGFRDRESDRGSSR
CCCCCCEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]