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The map label for this gene is yfnA [H]

Identifier: 192289020

GI number: 192289020

Start: 642477

End: 643946

Strand: Reverse

Name: yfnA [H]

Synonym: Rpal_0590

Alternate gene names: 192289020

Gene position: 643946-642477 (Counterclockwise)

Preceding gene: 192289021

Following gene: 192289019

Centisome position: 11.21

GC content: 67.55

Gene sequence:

>1470_bases
GTGGCCGGGATCTGGACGCGTAAATCTCTGAGCAGCCTGCAAATCGAGGCTGCGGCCGGGGACAGCGGCGACGGCGAGGT
CCGCCACCTGAAGCGGTCGCTGTCGGCGGTCAATCTGGTCGCCCTCGGGGTCGGTGGCATCATCGGTGCCGGCATCTTCG
TGCTCACCGGCCACGCCGCCGCCGCCAATGCCGGGCCGGCGGTGTCGCTGTCGTTCCTGCTCGGCGCGATCACCTGCGCG
TTCGCCGGGCTGTGCTACGCCGAGATGGCCTCGACCGTGCCGGTTTCTGGCAGCGCCTACACCTATGCGTATGCGACGAT
CGGCGAGCTGGTGGCCTGGATCATCGGGTGGGACCTGATCCTGGAATACGCGGTCGGCGCCATCACGGTGGCGATCGGCT
GGTCCGGTTACTTCGTCAGCCTGCTCGGCAATTTCGGCATCCATCTGCTGCCGCAGTTCACCACGGCGCCGCTCGCTTAC
GACGCCGCAACCCACGCCTGGTCGACCACCGGGGCGTTTCTCAACCTGCCGGCAATAGCGATCGTCGTCGCGATCGCCAC
ACTGCTGGTGATCGGCATCCAGGAATCGGCGCGGTTCAACAACGTCATCGTCGGCATCAAGCTGACGGTGATCGCGCTGT
TTCTGATCTTCGCCGCTCCGATGGTGACGCCGGCCAACTGGGTGACGGCGGCCAATCCGGATGGCGCGTTCATTCCACCG
GCGCAGGAGAACGGCATCTTCGGCTGGTCCGGCGTGCTGCGCGGCGCCGCGGTGGTGTTCTTCGCCTTCATCGGGTTCGA
CGCGGTCTCGACCGCCGCCCAGGAAGCCAAGAACCCGCAGCGCGACATGCCGCTCGGCATCCTCGGCTCGCTGGCGATCT
GCACCGTGCTGTATGTCTCGGTCGCATTCGTGCTGACCGGGATCGTGCCGTACGACCGGCTCAACGTGCCCGATCCGATC
GCGGTCGGGATCGACGCCGCCGGGATCGGCTGGCTGTCCTCGATCGTCAAGATCGGCGTCGTCACCGGGCTGACCTCGGT
AATCCTGGTGCTGATGCTCGGGCAGACCCGCGTGCTGCGGGCGATGGCGCATGACGGCCTGATGCCGAGGGGCGCCGCCG
CCACCCACCCGCGCTTCCGCACCCCGCATGTCGCCACCATCGGCACCGGCGTGATCGTCGCCGGCCTTGCCGGGGTGCTG
CCGATCGGACTGGTCGGCGAATTGGTCAGCATCGGCACGCTGTTCGCGTTCGCGGTGGTCTGCGTCGGCGTGCTGGCGCT
GCGGATCAAGCATCCCGAGCAGCACCGCCCGTTCAAGGTGCCGGCGATCTGGCTGGTGGCGCCGGCCGGGGCGATCGTAT
CGTTCATCCTGATGCTTGGCCTGCCGCTCGATACCTGGATACGGCTGGCGGTGTGGCTGGCGATCTACTTCCTGTACGGC
CGTCATCACAGCAAGCCCGCGAGGCGCTAA

Upstream 100 bases:

>100_bases
ATGGTGCCGCCAGAGGCGAGCGCCGGCGCAATGGAACCCGGCGGCCGTCGCCGCGCTTGAGATCGAGCGGGTTCCGCCGC
AGGGCAATGGGGGTTCGAGA

Downstream 100 bases:

>100_bases
GCTCAGCGGATGACGGCCAGGAGGCCCCGATGAGCACGAGCCCCGAACACAAACGCACCGCGCTGGTCACCGGCGCCAAT
TCCGGCCTCGGCAAGGCCAT

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MAGIWTRKSLSSLQIEAAAGDSGDGEVRHLKRSLSAVNLVALGVGGIIGAGIFVLTGHAAAANAGPAVSLSFLLGAITCA
FAGLCYAEMASTVPVSGSAYTYAYATIGELVAWIIGWDLILEYAVGAITVAIGWSGYFVSLLGNFGIHLLPQFTTAPLAY
DAATHAWSTTGAFLNLPAIAIVVAIATLLVIGIQESARFNNVIVGIKLTVIALFLIFAAPMVTPANWVTAANPDGAFIPP
AQENGIFGWSGVLRGAAVVFFAFIGFDAVSTAAQEAKNPQRDMPLGILGSLAICTVLYVSVAFVLTGIVPYDRLNVPDPI
AVGIDAAGIGWLSSIVKIGVVTGLTSVILVLMLGQTRVLRAMAHDGLMPRGAAATHPRFRTPHVATIGTGVIVAGLAGVL
PIGLVGELVSIGTLFAFAVVCVGVLALRIKHPEQHRPFKVPAIWLVAPAGAIVSFILMLGLPLDTWIRLAVWLAIYFLYG
RHHSKPARR

Sequences:

>Translated_489_residues
MAGIWTRKSLSSLQIEAAAGDSGDGEVRHLKRSLSAVNLVALGVGGIIGAGIFVLTGHAAAANAGPAVSLSFLLGAITCA
FAGLCYAEMASTVPVSGSAYTYAYATIGELVAWIIGWDLILEYAVGAITVAIGWSGYFVSLLGNFGIHLLPQFTTAPLAY
DAATHAWSTTGAFLNLPAIAIVVAIATLLVIGIQESARFNNVIVGIKLTVIALFLIFAAPMVTPANWVTAANPDGAFIPP
AQENGIFGWSGVLRGAAVVFFAFIGFDAVSTAAQEAKNPQRDMPLGILGSLAICTVLYVSVAFVLTGIVPYDRLNVPDPI
AVGIDAAGIGWLSSIVKIGVVTGLTSVILVLMLGQTRVLRAMAHDGLMPRGAAATHPRFRTPHVATIGTGVIVAGLAGVL
PIGLVGELVSIGTLFAFAVVCVGVLALRIKHPEQHRPFKVPAIWLVAPAGAIVSFILMLGLPLDTWIRLAVWLAIYFLYG
RHHSKPARR
>Mature_488_residues
AGIWTRKSLSSLQIEAAAGDSGDGEVRHLKRSLSAVNLVALGVGGIIGAGIFVLTGHAAAANAGPAVSLSFLLGAITCAF
AGLCYAEMASTVPVSGSAYTYAYATIGELVAWIIGWDLILEYAVGAITVAIGWSGYFVSLLGNFGIHLLPQFTTAPLAYD
AATHAWSTTGAFLNLPAIAIVVAIATLLVIGIQESARFNNVIVGIKLTVIALFLIFAAPMVTPANWVTAANPDGAFIPPA
QENGIFGWSGVLRGAAVVFFAFIGFDAVSTAAQEAKNPQRDMPLGILGSLAICTVLYVSVAFVLTGIVPYDRLNVPDPIA
VGIDAAGIGWLSSIVKIGVVTGLTSVILVLMLGQTRVLRAMAHDGLMPRGAAATHPRFRTPHVATIGTGVIVAGLAGVLP
IGLVGELVSIGTLFAFAVVCVGVLALRIKHPEQHRPFKVPAIWLVAPAGAIVSFILMLGLPLDTWIRLAVWLAIYFLYGR
HHSKPARR

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI114326544, Length=428, Percent_Identity=38.3177570093458, Blast_Score=249, Evalue=6e-66,
Organism=Homo sapiens, GI114326550, Length=428, Percent_Identity=38.3177570093458, Blast_Score=249, Evalue=6e-66,
Organism=Homo sapiens, GI258614003, Length=419, Percent_Identity=35.0835322195704, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI258614005, Length=419, Percent_Identity=35.0835322195704, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI258645169, Length=419, Percent_Identity=36.0381861575179, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI4507047, Length=438, Percent_Identity=36.5296803652968, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI181337167, Length=408, Percent_Identity=37.5, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI110347453, Length=403, Percent_Identity=36.2282878411911, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI186910308, Length=496, Percent_Identity=24.7983870967742, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI186910306, Length=496, Percent_Identity=24.7983870967742, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI186910304, Length=496, Percent_Identity=24.7983870967742, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI115648063, Length=441, Percent_Identity=23.5827664399093, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI115648022, Length=441, Percent_Identity=23.5827664399093, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI33286428, Length=489, Percent_Identity=24.9488752556237, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI7657683, Length=400, Percent_Identity=25.75, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI87081869, Length=491, Percent_Identity=23.8289205702648, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI87081708, Length=491, Percent_Identity=23.0142566191446, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786602, Length=481, Percent_Identity=24.3243243243243, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87082250, Length=453, Percent_Identity=25.3863134657837, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788480, Length=397, Percent_Identity=25.1889168765743, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081915, Length=431, Percent_Identity=25.0580046403712, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786302, Length=448, Percent_Identity=22.3214285714286, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786694, Length=402, Percent_Identity=24.6268656716418, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790653, Length=457, Percent_Identity=21.8818380743982, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789017, Length=365, Percent_Identity=24.3835616438356, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87082023, Length=253, Percent_Identity=25.6916996047431, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=403, Percent_Identity=34.4913151364764, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17531343, Length=411, Percent_Identity=32.360097323601, Blast_Score=194, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI17533459, Length=412, Percent_Identity=32.7669902912621, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17540018, Length=482, Percent_Identity=26.3485477178423, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17537453, Length=422, Percent_Identity=23.2227488151659, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17568033, Length=392, Percent_Identity=23.7244897959184, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32566699, Length=394, Percent_Identity=23.0964467005076, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24668806, Length=449, Percent_Identity=36.7483296213808, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI21356285, Length=449, Percent_Identity=36.7483296213808, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24668802, Length=449, Percent_Identity=36.7483296213808, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24666159, Length=422, Percent_Identity=36.2559241706161, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI221512776, Length=422, Percent_Identity=36.2559241706161, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24667468, Length=415, Percent_Identity=33.4939759036145, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI281366235, Length=409, Percent_Identity=35.4523227383863, Blast_Score=212, Evalue=5e-55,
Organism=Drosophila melanogaster, GI116007820, Length=409, Percent_Identity=35.4523227383863, Blast_Score=212, Evalue=5e-55,
Organism=Drosophila melanogaster, GI116007818, Length=413, Percent_Identity=35.8353510895884, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI85725152, Length=413, Percent_Identity=35.8353510895884, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI161077963, Length=424, Percent_Identity=33.4905660377358, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI221331183, Length=444, Percent_Identity=25.4504504504505, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17647653, Length=444, Percent_Identity=25.4504504504505, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24664379, Length=444, Percent_Identity=25.4504504504505, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45550968, Length=448, Percent_Identity=24.1071428571429, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19921172, Length=448, Percent_Identity=24.1071428571429, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24651635, Length=446, Percent_Identity=22.6457399103139, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24651633, Length=446, Percent_Identity=22.6457399103139, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357367, Length=443, Percent_Identity=21.8961625282167, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50928; Mature: 50796

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGIWTRKSLSSLQIEAAAGDSGDGEVRHLKRSLSAVNLVALGVGGIIGAGIFVLTGHAA
CCCCCCCCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
AANAGPAVSLSFLLGAITCAFAGLCYAEMASTVPVSGSAYTYAYATIGELVAWIIGWDLI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LEYAVGAITVAIGWSGYFVSLLGNFGIHLLPQFTTAPLAYDAATHAWSTTGAFLNLPAIA
HHHHHHHEEEEECCHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHCCCCCCCHHHHHHHH
IVVAIATLLVIGIQESARFNNVIVGIKLTVIALFLIFAAPMVTPANWVTAANPDGAFIPP
HHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCC
AQENGIFGWSGVLRGAAVVFFAFIGFDAVSTAAQEAKNPQRDMPLGILGSLAICTVLYVS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VAFVLTGIVPYDRLNVPDPIAVGIDAAGIGWLSSIVKIGVVTGLTSVILVLMLGQTRVLR
HHHHHHHCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AMAHDGLMPRGAAATHPRFRTPHVATIGTGVIVAGLAGVLPIGLVGELVSIGTLFAFAVV
HHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CVGVLALRIKHPEQHRPFKVPAIWLVAPAGAIVSFILMLGLPLDTWIRLAVWLAIYFLYG
HHHHHHHHHCCCCCCCCEECCEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RHHSKPARR
CCCCCCCCC
>Mature Secondary Structure 
AGIWTRKSLSSLQIEAAAGDSGDGEVRHLKRSLSAVNLVALGVGGIIGAGIFVLTGHAA
CCCCCCCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
AANAGPAVSLSFLLGAITCAFAGLCYAEMASTVPVSGSAYTYAYATIGELVAWIIGWDLI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LEYAVGAITVAIGWSGYFVSLLGNFGIHLLPQFTTAPLAYDAATHAWSTTGAFLNLPAIA
HHHHHHHEEEEECCHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHCCCCCCCHHHHHHHH
IVVAIATLLVIGIQESARFNNVIVGIKLTVIALFLIFAAPMVTPANWVTAANPDGAFIPP
HHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCC
AQENGIFGWSGVLRGAAVVFFAFIGFDAVSTAAQEAKNPQRDMPLGILGSLAICTVLYVS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VAFVLTGIVPYDRLNVPDPIAVGIDAAGIGWLSSIVKIGVVTGLTSVILVLMLGQTRVLR
HHHHHHHCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AMAHDGLMPRGAAATHPRFRTPHVATIGTGVIVAGLAGVLPIGLVGELVSIGTLFAFAVV
HHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CVGVLALRIKHPEQHRPFKVPAIWLVAPAGAIVSFILMLGLPLDTWIRLAVWLAIYFLYG
HHHHHHHHHCCCCCCCCEECCEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RHHSKPARR
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]