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The map label for this gene is 192288992

Identifier: 192288992

GI number: 192288992

Start: 611033

End: 612454

Strand: Reverse

Name: 192288992

Synonym: Rpal_0562

Alternate gene names: NA

Gene position: 612454-611033 (Counterclockwise)

Preceding gene: 192288993

Following gene: 192288991

Centisome position: 10.66

GC content: 67.44

Gene sequence:

>1422_bases
ATGCCGATAGCCACCACTGCAGACCGCGCTTCGGAATTTCTCGGCGGCTTGTTCAACAGCCTCACCGAACGCGGCCGCAG
CCTGTTCGGGCTGACCAGCTCACAGCCGATGTCCGGGGACGAACTGATCGCGCTTAGTGAGACGCTGCTGTCGCGGCGGG
GTGAAGCATCCGGCGTCGCGCTGGCCGCATCGCTGCTCGCCGGCTACGAGGCTGCCGACGAAGACGACAAGCTGGCGTTT
CTCGATGCGCTCGCCGAACAGTTCGGGCCCGACCTCGCCGAACTCAACGCCGCGATCGAGGCGTTTCGCGCCGACGCCTC
GGCCGAGGCGACCGGTGAATTGCTCCGCGCCGCCGAGCCGCGCCGGCAGGAGCTGATCCGCCGCCTCAATCACGCGCCGG
GCGGCACCGCGGCGCTGGTGAAGATGCGCGAGGCGGTGCTGGCCCGCATCGCCGCGCATCCGCAGCTTCGTCACGTCGAC
GACGATTTCGTGCATCTGTTCACGTCGTGGTTCAATCGGGGATTTCTCGTGCTGCAGCGGATCGACTGGACGACGCCGGC
CAACATCCTGGAAAAGATAATCCGCTACGAGCAGGTACACACCATCCACGACTGGGACGATCTGCGCGCGCGGCTGGCCC
CGCCGGACCGGCGTTGCTACGGCTTCTTCCATCCGCGGCTGGTCGACGAGCCGCTGATCTTCGTCGAGGTCGCGCTGACC
AAGGACAGCCCGGCCGCGATCGCACCGCTGCTCGATCTCGAACGCGAGCCGATCGCCGCCAGCGATGCAACGACTGCGGT
GTTCTATTCGATCTCCAACACCCAGCAGGGCCTCGCCGGGATCTCGTTCGGCAATTTCCTGATCAAGCAGGTGGTGGAGG
AGATCAAGCGCGAGCTGCCGAACGTCCAGACCTTCGTGACGCTGTCGCCGGTGCCGGGCTTCGCCAAGTGGCTGAAGCGC
GAACGCGACAATCCGGACTCGACGCTGCTCGATGCCTCCGCGCGCACCGCGCTCGAAGCGCTCGATACGCCGAACTGGTT
CGACGATGCCGACACCGCCGACCGGCTGAAGCCGATCGTGCTGCAGCTCGCCGCGGCTTACTTCCTGCAGGCCAAGGGGC
CGAACGGCCGGCCGCTCGATCCGGTGGCCCGCTTCCACCTCGGCAACGGCGCGCGGCTCGACCGGCTGAATTTCCTCGGC
GACCGTTCGCCGAACGGCATGCGCCAGTCGCACGGGCTGATGGTCAACTACCTGTATGCGCTCGGCGACATTGAGGCCAA
CCACGAGGCGCTGTTCGAACGCGGCCAGATCGCCGCCGCCTCCGCGGTACGCAAGCTGGTGCCGACCAAGCCGGTGAGCA
GCGAGCCGCGCAAGGGCAACGCAAAGACTGCCAGCGCCCCGCAGGCCGCGCCGACGGCGTGA

Upstream 100 bases:

>100_bases
TGCTCATGCGTCTGGAAGGCGTTGTCCGGAACGTCTATGGTTGCGAGGTACCGCACTCCGTACGTGCGGCGAAGATGTCG
CAAGCCTGGGGATGAAGCTG

Downstream 100 bases:

>100_bases
GGACTATTGATGAGCGAAGCACGAGCCTCGTCGCTGCGAGCGTAGCGAAGCAAACCAGCTCAGTACACGTGTCTGGATTG
CTTCGACGCTGCGCTCCTTG

Product: Malonyl-CoA decarboxylase

Products: acetyl-CoA; CO2

Alternate protein names: Malonyl-CoA Decarboxylase Superfamily; Malonyl-CoA Decarboxylase Superfamily Protein; Malonyl-CoA Decarboxylase Protein; MCD Malonyl-CoA Decarboxylase MCD; Malonyl-CoA Decarboxylase Family Protein; Decarboxylase

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MPIATTADRASEFLGGLFNSLTERGRSLFGLTSSQPMSGDELIALSETLLSRRGEASGVALAASLLAGYEAADEDDKLAF
LDALAEQFGPDLAELNAAIEAFRADASAEATGELLRAAEPRRQELIRRLNHAPGGTAALVKMREAVLARIAAHPQLRHVD
DDFVHLFTSWFNRGFLVLQRIDWTTPANILEKIIRYEQVHTIHDWDDLRARLAPPDRRCYGFFHPRLVDEPLIFVEVALT
KDSPAAIAPLLDLEREPIAASDATTAVFYSISNTQQGLAGISFGNFLIKQVVEEIKRELPNVQTFVTLSPVPGFAKWLKR
ERDNPDSTLLDASARTALEALDTPNWFDDADTADRLKPIVLQLAAAYFLQAKGPNGRPLDPVARFHLGNGARLDRLNFLG
DRSPNGMRQSHGLMVNYLYALGDIEANHEALFERGQIAAASAVRKLVPTKPVSSEPRKGNAKTASAPQAAPTA

Sequences:

>Translated_473_residues
MPIATTADRASEFLGGLFNSLTERGRSLFGLTSSQPMSGDELIALSETLLSRRGEASGVALAASLLAGYEAADEDDKLAF
LDALAEQFGPDLAELNAAIEAFRADASAEATGELLRAAEPRRQELIRRLNHAPGGTAALVKMREAVLARIAAHPQLRHVD
DDFVHLFTSWFNRGFLVLQRIDWTTPANILEKIIRYEQVHTIHDWDDLRARLAPPDRRCYGFFHPRLVDEPLIFVEVALT
KDSPAAIAPLLDLEREPIAASDATTAVFYSISNTQQGLAGISFGNFLIKQVVEEIKRELPNVQTFVTLSPVPGFAKWLKR
ERDNPDSTLLDASARTALEALDTPNWFDDADTADRLKPIVLQLAAAYFLQAKGPNGRPLDPVARFHLGNGARLDRLNFLG
DRSPNGMRQSHGLMVNYLYALGDIEANHEALFERGQIAAASAVRKLVPTKPVSSEPRKGNAKTASAPQAAPTA
>Mature_472_residues
PIATTADRASEFLGGLFNSLTERGRSLFGLTSSQPMSGDELIALSETLLSRRGEASGVALAASLLAGYEAADEDDKLAFL
DALAEQFGPDLAELNAAIEAFRADASAEATGELLRAAEPRRQELIRRLNHAPGGTAALVKMREAVLARIAAHPQLRHVDD
DFVHLFTSWFNRGFLVLQRIDWTTPANILEKIIRYEQVHTIHDWDDLRARLAPPDRRCYGFFHPRLVDEPLIFVEVALTK
DSPAAIAPLLDLEREPIAASDATTAVFYSISNTQQGLAGISFGNFLIKQVVEEIKRELPNVQTFVTLSPVPGFAKWLKRE
RDNPDSTLLDASARTALEALDTPNWFDDADTADRLKPIVLQLAAAYFLQAKGPNGRPLDPVARFHLGNGARLDRLNFLGD
RSPNGMRQSHGLMVNYLYALGDIEANHEALFERGQIAAASAVRKLVPTKPVSSEPRKGNAKTASAPQAAPTA

Specific function: Unknown

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI110349750, Length=409, Percent_Identity=33.2518337408313, Blast_Score=211, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI71985309, Length=440, Percent_Identity=32.9545454545455, Blast_Score=213, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.1.1.9

Molecular weight: Translated: 51728; Mature: 51597

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIATTADRASEFLGGLFNSLTERGRSLFGLTSSQPMSGDELIALSETLLSRRGEASGVA
CCCCCCHHHHHHHHHHHHHHHHHHCHHEECCCCCCCCCCCHHHHHHHHHHHCCCCCCHHH
LAASLLAGYEAADEDDKLAFLDALAEQFGPDLAELNAAIEAFRADASAEATGELLRAAEP
HHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCH
RRQELIRRLNHAPGGTAALVKMREAVLARIAAHPQLRHVDDDFVHLFTSWFNRGFLVLQR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHCCCEEEEEE
IDWTTPANILEKIIRYEQVHTIHDWDDLRARLAPPDRRCYGFFHPRLVDEPLIFVEVALT
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHCCCCEEEEEEEEC
KDSPAAIAPLLDLEREPIAASDATTAVFYSISNTQQGLAGISFGNFLIKQVVEEIKRELP
CCCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHCHHHHHHHHHHHHHHHHHCC
NVQTFVTLSPVPGFAKWLKRERDNPDSTLLDASARTALEALDTPNWFDDADTADRLKPIV
CCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LQLAAAYFLQAKGPNGRPLDPVARFHLGNGARLDRLNFLGDRSPNGMRQSHGLMVNYLYA
HHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCHHHHHCCCCCCCCCHHHCCHHHHHHHH
LGDIEANHEALFERGQIAAASAVRKLVPTKPVSSEPRKGNAKTASAPQAAPTA
HHCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PIATTADRASEFLGGLFNSLTERGRSLFGLTSSQPMSGDELIALSETLLSRRGEASGVA
CCCCCHHHHHHHHHHHHHHHHHHCHHEECCCCCCCCCCCHHHHHHHHHHHCCCCCCHHH
LAASLLAGYEAADEDDKLAFLDALAEQFGPDLAELNAAIEAFRADASAEATGELLRAAEP
HHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCH
RRQELIRRLNHAPGGTAALVKMREAVLARIAAHPQLRHVDDDFVHLFTSWFNRGFLVLQR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHCCCEEEEEE
IDWTTPANILEKIIRYEQVHTIHDWDDLRARLAPPDRRCYGFFHPRLVDEPLIFVEVALT
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHCCCCEEEEEEEEC
KDSPAAIAPLLDLEREPIAASDATTAVFYSISNTQQGLAGISFGNFLIKQVVEEIKRELP
CCCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHCHHHHHHHHHHHHHHHHHCC
NVQTFVTLSPVPGFAKWLKRERDNPDSTLLDASARTALEALDTPNWFDDADTADRLKPIV
CCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LQLAAAYFLQAKGPNGRPLDPVARFHLGNGARLDRLNFLGDRSPNGMRQSHGLMVNYLYA
HHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCHHHHHCCCCCCCCCHHHCCHHHHHHHH
LGDIEANHEALFERGQIAAASAVRKLVPTKPVSSEPRKGNAKTASAPQAAPTA
HHCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: malonyl-CoA

Specific reaction: malonyl-CoA = acetyl-CoA + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA