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The map label for this gene is cat1 [H]

Identifier: 192288968

GI number: 192288968

Start: 587743

End: 589302

Strand: Reverse

Name: cat1 [H]

Synonym: Rpal_0538

Alternate gene names: 192288968

Gene position: 589302-587743 (Counterclockwise)

Preceding gene: 192288969

Following gene: 192288966

Centisome position: 10.26

GC content: 64.36

Gene sequence:

>1560_bases
ATGGTCAACGCCGAGCGCATCCTTGCTCCTCACCTCCGCTCCAAGGTCATGACCGCAGCTGACGCTGCCGCGCTGATTCC
GTCCGGCGCGCATGTCGGCATGAGCGGCTTCACCGGCGCGGGTTATCCGAAGCTGCTGCCGCTGGCGCTCGCCGAGCGCA
TCAACGCGCATCACGCCCGCGGCCAGAAGTTCAAGGTCAGCGTCTGGACCGGCGCCTCGACGGCGCCCGAGCTCGACGGT
GCACTCGCCAAGGTCGACGGCATCGAGATGCGGCTGCCCTATCAATCCGATCCGACCTGCCGCAAGCGCATCAACGCCGG
GCGGATGGAATACATCGACATCCATCTGTCCCACGTCGCCCAGCACGCCTGGTTCGGCTTCCTCGGTAAGCTCGACATTG
CTGTGGTCGAAGTCGCCGGCATCCGCGAGGACGGCAGCCTGATCCCGTCGTCGTCGATCGGCAACAACAAGACTTGGCTC
GATCTCGCCGACAAGGTCATCCTCGAGGTCAACGCCTGGCAGGACATTCGCCTCGAAGGCATGCATGACGTCTATTACGG
CACGCAGCTGCCGCCGAACCGCAAACCGATTCCGATCATCGCCTCCGGTGACCGCATCGGGGAGCAGTATCTGCGCTGCG
ATTCCGCCAAGATCGTCGCGATCGTCGAGACCAACCTGCCCGATCGCAACTCGGCGTTCTCGCCGCCCGACGACACCTCG
CAGGCGATCGCCGGCCACATCCTGGATTTCCTCGGCCACGAGGTGAAGAAGGGCCGGCTGCCGCACAACCTGTTGCCGCT
GCAATCGGGCGTCGGCAACGTCGCCAATGCGGTGATGGCCGGCCTCGAAGATGGCCCGTTCGACAATCTCACCGCCTATA
CCGAAGTGCTGCAGGACGGCATGCTGCACCTGTTGCGCAAGGGAAAGCTGGCTCACGCCTCGGCGACCGCGTTGTCGCTG
TCACCGGAAGGCTACGATGAATTCCTGCGCAATCTCGACTTCTATCGCGAGCGCATCGTGCTGCGTCAGCAGGAGATTTC
CAACCATCCGGAAGTGATCCGCCGGCTCGGCGTGATCGCCATGAACGGCATGATCGAGGCCGACATCTACGGCAACGTCA
ACTCGACCCACGTGATGGGCACCAGCATCATGAACGGCATCGGCGGCTCCGGCGACTTCGCCCGCAACAGCTTCCTGTCG
TTCTTCATGACGCCGTCGGCCGCCAAGGGCGGCAAGATCTCCTGCATCGTGCCGATGACCTCGCATGTCGACCACACCGA
GCACGACGTTCAGGTGATCGTCACCGAGCAGGGGCTCGCCGATCTGCGCGGCCTGTCGCCGAAGCAGCGCGCCAAGGTGA
TCATCGAGAACTGCGCGCACCCGACCTTCCGGCCGGCCTTGAAGGAATACTTCAAGCGCGCGCTGGAATATTCGCCGGGC
CTGCACACCCCGCACATTCTCGACGAAGCGCTGACCTTCCTGCCAAACTGGATGGCCAACAAGGCCGCGCGCGAAGCCTG
GCGCGACGACGCCGTGGTGCAGGCCGACGCCTGGCGGTAG

Upstream 100 bases:

>100_bases
CGCATGCCTCCTTCGCCATAGGTTGCATGGCTCTTTCTGTCACAGCGACTAGACGAATCGCATCAATCCCCTGGCCGCTC
CTAGCAAGAAAGAGTCGTTG

Downstream 100 bases:

>100_bases
GGACCGGCCACGTCCCTCTCGACGTCATTGCGAGCGAAGCGAGCAATCCAGAGCTCCCTGCACCGAGCTGGATTGCTTCG
TCGCTTCGCTCCTCGCAATA

Product: succinate CoA transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MVNAERILAPHLRSKVMTAADAAALIPSGAHVGMSGFTGAGYPKLLPLALAERINAHHARGQKFKVSVWTGASTAPELDG
ALAKVDGIEMRLPYQSDPTCRKRINAGRMEYIDIHLSHVAQHAWFGFLGKLDIAVVEVAGIREDGSLIPSSSIGNNKTWL
DLADKVILEVNAWQDIRLEGMHDVYYGTQLPPNRKPIPIIASGDRIGEQYLRCDSAKIVAIVETNLPDRNSAFSPPDDTS
QAIAGHILDFLGHEVKKGRLPHNLLPLQSGVGNVANAVMAGLEDGPFDNLTAYTEVLQDGMLHLLRKGKLAHASATALSL
SPEGYDEFLRNLDFYRERIVLRQQEISNHPEVIRRLGVIAMNGMIEADIYGNVNSTHVMGTSIMNGIGGSGDFARNSFLS
FFMTPSAAKGGKISCIVPMTSHVDHTEHDVQVIVTEQGLADLRGLSPKQRAKVIIENCAHPTFRPALKEYFKRALEYSPG
LHTPHILDEALTFLPNWMANKAAREAWRDDAVVQADAWR

Sequences:

>Translated_519_residues
MVNAERILAPHLRSKVMTAADAAALIPSGAHVGMSGFTGAGYPKLLPLALAERINAHHARGQKFKVSVWTGASTAPELDG
ALAKVDGIEMRLPYQSDPTCRKRINAGRMEYIDIHLSHVAQHAWFGFLGKLDIAVVEVAGIREDGSLIPSSSIGNNKTWL
DLADKVILEVNAWQDIRLEGMHDVYYGTQLPPNRKPIPIIASGDRIGEQYLRCDSAKIVAIVETNLPDRNSAFSPPDDTS
QAIAGHILDFLGHEVKKGRLPHNLLPLQSGVGNVANAVMAGLEDGPFDNLTAYTEVLQDGMLHLLRKGKLAHASATALSL
SPEGYDEFLRNLDFYRERIVLRQQEISNHPEVIRRLGVIAMNGMIEADIYGNVNSTHVMGTSIMNGIGGSGDFARNSFLS
FFMTPSAAKGGKISCIVPMTSHVDHTEHDVQVIVTEQGLADLRGLSPKQRAKVIIENCAHPTFRPALKEYFKRALEYSPG
LHTPHILDEALTFLPNWMANKAAREAWRDDAVVQADAWR
>Mature_519_residues
MVNAERILAPHLRSKVMTAADAAALIPSGAHVGMSGFTGAGYPKLLPLALAERINAHHARGQKFKVSVWTGASTAPELDG
ALAKVDGIEMRLPYQSDPTCRKRINAGRMEYIDIHLSHVAQHAWFGFLGKLDIAVVEVAGIREDGSLIPSSSIGNNKTWL
DLADKVILEVNAWQDIRLEGMHDVYYGTQLPPNRKPIPIIASGDRIGEQYLRCDSAKIVAIVETNLPDRNSAFSPPDDTS
QAIAGHILDFLGHEVKKGRLPHNLLPLQSGVGNVANAVMAGLEDGPFDNLTAYTEVLQDGMLHLLRKGKLAHASATALSL
SPEGYDEFLRNLDFYRERIVLRQQEISNHPEVIRRLGVIAMNGMIEADIYGNVNSTHVMGTSIMNGIGGSGDFARNSFLS
FFMTPSAAKGGKISCIVPMTSHVDHTEHDVQVIVTEQGLADLRGLSPKQRAKVIIENCAHPTFRPALKEYFKRALEYSPG
LHTPHILDEALTFLPNWMANKAAREAWRDDAVVQADAWR

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=484, Percent_Identity=48.5537190082645, Blast_Score=461, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI17538151, Length=483, Percent_Identity=25.0517598343685, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6319456, Length=502, Percent_Identity=45.2191235059761, Blast_Score=421, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 56810; Mature: 56810

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNAERILAPHLRSKVMTAADAAALIPSGAHVGMSGFTGAGYPKLLPLALAERINAHHAR
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
GQKFKVSVWTGASTAPELDGALAKVDGIEMRLPYQSDPTCRKRINAGRMEYIDIHLSHVA
CCEEEEEEEECCCCCCCCCCHHHHCCCEEEECCCCCCCHHHHHCCCCCEEEEEEHHHHHH
QHAWFGFLGKLDIAVVEVAGIREDGSLIPSSSIGNNKTWLDLADKVILEVNAWQDIRLEG
HHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHCEEEEEECCCCCEEECC
MHDVYYGTQLPPNRKPIPIIASGDRIGEQYLRCDSAKIVAIVETNLPDRNSAFSPPDDTS
CHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHH
QAIAGHILDFLGHEVKKGRLPHNLLPLQSGVGNVANAVMAGLEDGPFDNLTAYTEVLQDG
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
MLHLLRKGKLAHASATALSLSPEGYDEFLRNLDFYRERIVLRQQEISNHPEVIRRLGVIA
HHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
MNGMIEADIYGNVNSTHVMGTSIMNGIGGSGDFARNSFLSFFMTPSAAKGGKISCIVPMT
CCCEEEEEEECCCCCCEEEHHHHHHCCCCCCCHHHHHHHHHEECCCCCCCCEEEEEEECC
SHVDHTEHDVQVIVTEQGLADLRGLSPKQRAKVIIENCAHPTFRPALKEYFKRALEYSPG
CCCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
LHTPHILDEALTFLPNWMANKAAREAWRDDAVVQADAWR
CCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCCCC
>Mature Secondary Structure
MVNAERILAPHLRSKVMTAADAAALIPSGAHVGMSGFTGAGYPKLLPLALAERINAHHAR
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
GQKFKVSVWTGASTAPELDGALAKVDGIEMRLPYQSDPTCRKRINAGRMEYIDIHLSHVA
CCEEEEEEEECCCCCCCCCCHHHHCCCEEEECCCCCCCHHHHHCCCCCEEEEEEHHHHHH
QHAWFGFLGKLDIAVVEVAGIREDGSLIPSSSIGNNKTWLDLADKVILEVNAWQDIRLEG
HHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHCEEEEEECCCCCEEECC
MHDVYYGTQLPPNRKPIPIIASGDRIGEQYLRCDSAKIVAIVETNLPDRNSAFSPPDDTS
CHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHH
QAIAGHILDFLGHEVKKGRLPHNLLPLQSGVGNVANAVMAGLEDGPFDNLTAYTEVLQDG
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
MLHLLRKGKLAHASATALSLSPEGYDEFLRNLDFYRERIVLRQQEISNHPEVIRRLGVIA
HHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
MNGMIEADIYGNVNSTHVMGTSIMNGIGGSGDFARNSFLSFFMTPSAAKGGKISCIVPMT
CCCEEEEEEECCCCCCEEEHHHHHHCCCCCCCHHHHHHHHHEECCCCCCCCEEEEEEECC
SHVDHTEHDVQVIVTEQGLADLRGLSPKQRAKVIIENCAHPTFRPALKEYFKRALEYSPG
CCCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
LHTPHILDEALTFLPNWMANKAAREAWRDDAVVQADAWR
CCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]