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The map label for this gene is vbsS [H]

Identifier: 190895016

GI number: 190895016

Start: 737226

End: 741218

Strand: Reverse

Name: vbsS [H]

Synonym: RHECIAT_PC0000682

Alternate gene names: 190895016

Gene position: 741218-737226 (Counterclockwise)

Preceding gene: 190895017

Following gene: 190895015

Centisome position: 67.91

GC content: 64.99

Gene sequence:

>3993_bases
ATGAACAAGCAGATCACCAATTTCGCCGATGCCCGCCCGACCGACGCAGTGGACGCCGTCTTCGAGAGTTTTCCGCTGAC
CATCGCGCAGAAGCGCATCTGGTCGCTGGAGCAGATCGGCAATTACACCGTCTTTCCCGACCAGGTCATCGGGCTGCGGC
TGAGCGCCGCGATTGACGTCGAGACGATTGCCGGCGCCTGCCGGGCGCTCGTGGCGGACAATCCGTCGCTCGCCTCCCGT
TTCCGCAGGCTGGCGGGCGGCCGGATCGAGCAATATCGCGGCGCATCGAGCGCAGTGCCGGTCGAAATCCTCGGCACGGA
CGGCGCGGCTCTTTCCGAGCCGGATGCCTTGGCCGCACGGAAAGCCTTCCGCGACAAGCGCTTCGATCTCCTGGAGGGGC
CTGGTGCGCGCATCCAGATCATCCGGCTTGCCGATGGCCAGTCGCTGCTGACGATCGTGCTGCATCCGATCATCTGCGAC
GACCGCGAAAAATCCGTTCTTGCCCGTTCGCTGGCCCGCATTCTCGATGGCGAACCCGCCGGCGACATGCAGCCGGTGGA
AATCGCCGCCGGGACGCGGGAGGCCGATTGGCTGGAGACGGATGAGGCGCGGCAAGCGCTTGCCTATTGGCGCGATGCGA
TCGGCCTCGACTATGCCGCCTCGACCTTCCCGACCCGCTTCAACAGCGGCGGGCTGGCAGGTGTGGCGCGCGCCGAGCAT
CGGTTTTCGATCGAGCCCGACCTCTGGAGCAAACTCGAACGGCATGCGGGGCGCAAGGACGTTCAGGTCGAGCGCGTGCT
TCACGCCGCCTTCTGCGCTCTGCTGGCGCGCTACAGCGGCAACTATGCCCTGCTGACCGGCCTGCTCGTTGCGCGGCCCC
GCACCGAGCATTTCGCCAGCCGCGGCCGCGCCGAACAGGTTCTTCCCCTCGTGCTTTCGCTGACATCAAGGCATTCGCTC
GATGATGTCGTCGCGGCGATTTCGTCGGTGACGCAGGAAGGGCTTGCCCGCCTCGTGCCGCTGGAGCGCATCACGCAGGA
ACTGGTCGTCGACGAGGCCGCCGCGCAAGAAGCCGTGGTCAAGGCTCTGTTCGAATTCCGCGAGCCTTATCCGGTCCCAA
GGCAGGCGACGAACCTGGAACCTTCGGGCGCACGTGCCGACAGCGAGCTTTCCCTGGTGATCGAGGCGCGTGCCGATGGC
GCCGCATACGGGCTGATCGACTATGCCGGGGATCTCTATGACGGCGCCCTGATTGCCCGTGTCGCCAGGCATTTTTGCCT
GGTGCTGGAGCAGATCGTCGCGAAGCCGGATCTCAGGATCAAGGATATCGAGCTCATGGGCAGCGACGAGCTCGACTGGC
TGTCTGCACCCTATGAGGATGACGTCGTCAACGACGACCGGCCGGTCCACGAGCTGATTTCGGCCCATTCGCGCCGCACG
CCCGACAAAACGGCGATCGTCTATGGCGACGAGGAGTGGAGCCATGGCTGGCTGGAGGCGAGCACCAACCGCCTTGGGCA
TCGGCTGCGGCAGCTCGGCGTTCGCGCCGAAGTGACGGTCGCGATCTTCATCAAGCGCTCGCCGGAGGCGATCGTCGGCA
TCCTCGCCACCCTGAAGGCCGGCGGCGCCTATATTCCTGTTGAGCCCGGCCATCCGCCGGTGCGCAACCACCACATCCTA
CGTGATGGCGACGTCAAGATCGTGCTCACCCATAGCTGGCTGCGCCACCGCCTGCCGGAAGAGCTCGACGCGACCGTCCT
CGAACTCGACAAGCTCGATCTCGACGGCGAGCCGGATACGCCGCTCTGTGTTCCGACGCACAAGGACCAGCTCGCCTATG
TCATGTACACGTCGGGCTCGACGGGATTGCCGAAAGGCGTCGCCGTCGAGCACGGGCCGCTGACCCACCATCTGCAGAAT
ACCTCGCGCGTCTACGGCATGAGCTCGGAATCCCGCGAGCTGCCCTTCCTGCCCTTCAGTTCGGACGGCGGCCATGAGCG
GTGGATGAACCCGCTGATGGAAGGCGGCAGCATCATCCTTCCCGACCAGCCGCTGTGGACGCCGGAGGAGACGCTGACGG
CGATGCGCAAGCACGGCGCCAACAATGCCAGCATTCCCACAACCTATCTGCAGCAGCTGGCGGAATGGGCCGACATTACC
GATGGCGCGCCGCCGATGCGGCTATACTCCTTCGGCGGCGAGGGGCTGGCGCAATCGACCTTCGACCTCCTGTCGCGGGC
GCTGAAATCGGAATGGCTTATCAACGGCTACGGTCCCACGGAAACCATCATGACGCCGATGGTCTGGAAGGTGAGGGCCG
GCACGAAGTTCCAGGGCGTCTATGCGCCGCTCGGCCGCGCTGTCGGGCTCAGGCGCGTCTATGTGCTCGATCCCGACCTC
AACCTGTGCCCGATCGGCGTGACCGGCGAGCTCTATATCGGCGGCGAGGGCATCGCGCGCGGCTATCTCGGCAAAGCAGA
TACGACGGCCGACCGCTTCATTCCCGACCCGTTCTCGAAGGAGGGCGGCCGGCTTTATCGCTCCGGTGATCTCACGCGCT
GGCGTGAGGACGGAACGGTCGAATTCGTCGGCCGCGTCGACCATCAGGTGAAGCTGCGTGGTTACCGCATCGAGCTCGGT
GAGATCGAGGCCGCGCTGCTCCAGCAGCCCGGCGTCGGCGAGGCCTTGGTCGTGCTGCGCGATGACGATGCCGGCGGCGA
AAAGGCGCTGGTCGCCTATGTCGTGCCGAAGAAGGACGAAAGGCTTGACGTCGAGACGGTGCGCGCCGGCCTCGAACGCA
GCCTGCCATCCTACATGGTGCCGGCCTCCGTGGTCGAACTGGAGAAGATGCCGACCAATCCGAACAGCAAGCTCGACCGC
TTCGCGCTGCCCGCACCCCAGCCGGTCAAACGCGCCATCGTCGAGCCGGCGACGGCGCTGGAAGAGGAGGTGCTGGATGT
CTGGCGCCAGGTTCTCAAGCTGGAAGCGATCAGCGTCGAGGATAATTTCTTCGCCATCGGCGGCAATTCGCTGGGCGCGA
TCCGCATCCTCACGCAGCTCAGGCAGCGCCGGCCGAAGGTTCCGCTGACCGTTGCCGATATCTTCAACAACCCGACCATC
CGCGCCTTTGCCGGCGTGATGGAGCAGGGGGAGGAGCGCGATCTCTCCGAGGTGATCGTGCTGCGCGCCTCCGGCGCCAA
GCCGCGACTCTATTGCTTCCCGGGGCTTCTGGTCAGCACCCGCGAATATGTGAAGCTCGTCGATTATCTCGGCGCCGACC
AGCCGGCGACCGGCTTCATTTGCCATTCGCTGTCGGAAAAGAAGGAAGTCGGCGCGCCGATCGAAGAGATCATCGAGCCC
TATGTCGATTATATCAGGACGCATAGCAAAGGCGCGCCCTGCACTTTCCTCGGCTGGTCCTGGGGCGGGCTTCTCGCCTA
TGAGGCCGCCCGCACCCTCGGCAACGAAGTCGATGTCAGGATGATGGCGATGGTCGACGTGTGCGATCTCGGCTCGGAAT
TCGCGATCGGCGCCAAGCCGCGCTTCCGCCCCGGCGAGCGCGGCGCGCTGCATCGCGACGTGCAGGCATGGCTGCAGAAA
ACGGCGATGCGGCCCGAATGGGACCGGCTGCTGTCGACCATGGACGCCGATACCTATGAGCAGTTCCTGCGCTTCGTCGG
CGACGAGAAGGATCCGCTTCCGACAGACGGGCCTGATATCAGCAGCCGCGAGCATACGTTCTGGGTGCTGATCGACAACG
CCCTGATCTTCCGCAAGCATCGGCTCGTTCCCCATGACGTGCCGATCTATCCCTGGGCGGCCGACGACAGCCTCAACCGC
GGCCTCAACCTGATCGATTGGCGCCGCCTGTCGCCACGGGCGCGGGCTGCCGAAATCATCACCGGCACCAACCATCTGCA
CATGATCGGGTCTCCCGCCTTCCATTCAAGGCTTGCCCTGCGTCTCAAGGAAACAGAGAAGGATAACGCATGA

Upstream 100 bases:

>100_bases
CCTGGCCCATATCCGCGGCGTCTGGACCGATCCCCGCCCGCTCTCCCTGCGCTCGGCGATGGCCGGCGATGCGCGTCTCT
GAAAACCTCTGGATGGCAAG

Downstream 100 bases:

>100_bases
CCGTCGCTTTTACCCGCAGGGACGCCCTCAACGAGCCGCTCGATCTTGCCGGGATCGGCATCGGTCCCTCCAATCTGAGC
CTCGCCTGCCTGCTGGAATC

Product: vicibactin biosynthesis non-ribosomal peptide synthase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Tyrocidine synthase III; ATP-dependent asparagine adenylase; AsnA; Asparagine activase; ATP-dependent glutamine adenylase; GlnA; Glutamine activase; ATP-dependent tyrosine adenylase; TyrA; Tyrosine activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 1330; Mature: 1330

Protein sequence:

>1330_residues
MNKQITNFADARPTDAVDAVFESFPLTIAQKRIWSLEQIGNYTVFPDQVIGLRLSAAIDVETIAGACRALVADNPSLASR
FRRLAGGRIEQYRGASSAVPVEILGTDGAALSEPDALAARKAFRDKRFDLLEGPGARIQIIRLADGQSLLTIVLHPIICD
DREKSVLARSLARILDGEPAGDMQPVEIAAGTREADWLETDEARQALAYWRDAIGLDYAASTFPTRFNSGGLAGVARAEH
RFSIEPDLWSKLERHAGRKDVQVERVLHAAFCALLARYSGNYALLTGLLVARPRTEHFASRGRAEQVLPLVLSLTSRHSL
DDVVAAISSVTQEGLARLVPLERITQELVVDEAAAQEAVVKALFEFREPYPVPRQATNLEPSGARADSELSLVIEARADG
AAYGLIDYAGDLYDGALIARVARHFCLVLEQIVAKPDLRIKDIELMGSDELDWLSAPYEDDVVNDDRPVHELISAHSRRT
PDKTAIVYGDEEWSHGWLEASTNRLGHRLRQLGVRAEVTVAIFIKRSPEAIVGILATLKAGGAYIPVEPGHPPVRNHHIL
RDGDVKIVLTHSWLRHRLPEELDATVLELDKLDLDGEPDTPLCVPTHKDQLAYVMYTSGSTGLPKGVAVEHGPLTHHLQN
TSRVYGMSSESRELPFLPFSSDGGHERWMNPLMEGGSIILPDQPLWTPEETLTAMRKHGANNASIPTTYLQQLAEWADIT
DGAPPMRLYSFGGEGLAQSTFDLLSRALKSEWLINGYGPTETIMTPMVWKVRAGTKFQGVYAPLGRAVGLRRVYVLDPDL
NLCPIGVTGELYIGGEGIARGYLGKADTTADRFIPDPFSKEGGRLYRSGDLTRWREDGTVEFVGRVDHQVKLRGYRIELG
EIEAALLQQPGVGEALVVLRDDDAGGEKALVAYVVPKKDERLDVETVRAGLERSLPSYMVPASVVELEKMPTNPNSKLDR
FALPAPQPVKRAIVEPATALEEEVLDVWRQVLKLEAISVEDNFFAIGGNSLGAIRILTQLRQRRPKVPLTVADIFNNPTI
RAFAGVMEQGEERDLSEVIVLRASGAKPRLYCFPGLLVSTREYVKLVDYLGADQPATGFICHSLSEKKEVGAPIEEIIEP
YVDYIRTHSKGAPCTFLGWSWGGLLAYEAARTLGNEVDVRMMAMVDVCDLGSEFAIGAKPRFRPGERGALHRDVQAWLQK
TAMRPEWDRLLSTMDADTYEQFLRFVGDEKDPLPTDGPDISSREHTFWVLIDNALIFRKHRLVPHDVPIYPWAADDSLNR
GLNLIDWRRLSPRARAAEIITGTNHLHMIGSPAFHSRLALRLKETEKDNA

Sequences:

>Translated_1330_residues
MNKQITNFADARPTDAVDAVFESFPLTIAQKRIWSLEQIGNYTVFPDQVIGLRLSAAIDVETIAGACRALVADNPSLASR
FRRLAGGRIEQYRGASSAVPVEILGTDGAALSEPDALAARKAFRDKRFDLLEGPGARIQIIRLADGQSLLTIVLHPIICD
DREKSVLARSLARILDGEPAGDMQPVEIAAGTREADWLETDEARQALAYWRDAIGLDYAASTFPTRFNSGGLAGVARAEH
RFSIEPDLWSKLERHAGRKDVQVERVLHAAFCALLARYSGNYALLTGLLVARPRTEHFASRGRAEQVLPLVLSLTSRHSL
DDVVAAISSVTQEGLARLVPLERITQELVVDEAAAQEAVVKALFEFREPYPVPRQATNLEPSGARADSELSLVIEARADG
AAYGLIDYAGDLYDGALIARVARHFCLVLEQIVAKPDLRIKDIELMGSDELDWLSAPYEDDVVNDDRPVHELISAHSRRT
PDKTAIVYGDEEWSHGWLEASTNRLGHRLRQLGVRAEVTVAIFIKRSPEAIVGILATLKAGGAYIPVEPGHPPVRNHHIL
RDGDVKIVLTHSWLRHRLPEELDATVLELDKLDLDGEPDTPLCVPTHKDQLAYVMYTSGSTGLPKGVAVEHGPLTHHLQN
TSRVYGMSSESRELPFLPFSSDGGHERWMNPLMEGGSIILPDQPLWTPEETLTAMRKHGANNASIPTTYLQQLAEWADIT
DGAPPMRLYSFGGEGLAQSTFDLLSRALKSEWLINGYGPTETIMTPMVWKVRAGTKFQGVYAPLGRAVGLRRVYVLDPDL
NLCPIGVTGELYIGGEGIARGYLGKADTTADRFIPDPFSKEGGRLYRSGDLTRWREDGTVEFVGRVDHQVKLRGYRIELG
EIEAALLQQPGVGEALVVLRDDDAGGEKALVAYVVPKKDERLDVETVRAGLERSLPSYMVPASVVELEKMPTNPNSKLDR
FALPAPQPVKRAIVEPATALEEEVLDVWRQVLKLEAISVEDNFFAIGGNSLGAIRILTQLRQRRPKVPLTVADIFNNPTI
RAFAGVMEQGEERDLSEVIVLRASGAKPRLYCFPGLLVSTREYVKLVDYLGADQPATGFICHSLSEKKEVGAPIEEIIEP
YVDYIRTHSKGAPCTFLGWSWGGLLAYEAARTLGNEVDVRMMAMVDVCDLGSEFAIGAKPRFRPGERGALHRDVQAWLQK
TAMRPEWDRLLSTMDADTYEQFLRFVGDEKDPLPTDGPDISSREHTFWVLIDNALIFRKHRLVPHDVPIYPWAADDSLNR
GLNLIDWRRLSPRARAAEIITGTNHLHMIGSPAFHSRLALRLKETEKDNA
>Mature_1330_residues
MNKQITNFADARPTDAVDAVFESFPLTIAQKRIWSLEQIGNYTVFPDQVIGLRLSAAIDVETIAGACRALVADNPSLASR
FRRLAGGRIEQYRGASSAVPVEILGTDGAALSEPDALAARKAFRDKRFDLLEGPGARIQIIRLADGQSLLTIVLHPIICD
DREKSVLARSLARILDGEPAGDMQPVEIAAGTREADWLETDEARQALAYWRDAIGLDYAASTFPTRFNSGGLAGVARAEH
RFSIEPDLWSKLERHAGRKDVQVERVLHAAFCALLARYSGNYALLTGLLVARPRTEHFASRGRAEQVLPLVLSLTSRHSL
DDVVAAISSVTQEGLARLVPLERITQELVVDEAAAQEAVVKALFEFREPYPVPRQATNLEPSGARADSELSLVIEARADG
AAYGLIDYAGDLYDGALIARVARHFCLVLEQIVAKPDLRIKDIELMGSDELDWLSAPYEDDVVNDDRPVHELISAHSRRT
PDKTAIVYGDEEWSHGWLEASTNRLGHRLRQLGVRAEVTVAIFIKRSPEAIVGILATLKAGGAYIPVEPGHPPVRNHHIL
RDGDVKIVLTHSWLRHRLPEELDATVLELDKLDLDGEPDTPLCVPTHKDQLAYVMYTSGSTGLPKGVAVEHGPLTHHLQN
TSRVYGMSSESRELPFLPFSSDGGHERWMNPLMEGGSIILPDQPLWTPEETLTAMRKHGANNASIPTTYLQQLAEWADIT
DGAPPMRLYSFGGEGLAQSTFDLLSRALKSEWLINGYGPTETIMTPMVWKVRAGTKFQGVYAPLGRAVGLRRVYVLDPDL
NLCPIGVTGELYIGGEGIARGYLGKADTTADRFIPDPFSKEGGRLYRSGDLTRWREDGTVEFVGRVDHQVKLRGYRIELG
EIEAALLQQPGVGEALVVLRDDDAGGEKALVAYVVPKKDERLDVETVRAGLERSLPSYMVPASVVELEKMPTNPNSKLDR
FALPAPQPVKRAIVEPATALEEEVLDVWRQVLKLEAISVEDNFFAIGGNSLGAIRILTQLRQRRPKVPLTVADIFNNPTI
RAFAGVMEQGEERDLSEVIVLRASGAKPRLYCFPGLLVSTREYVKLVDYLGADQPATGFICHSLSEKKEVGAPIEEIIEP
YVDYIRTHSKGAPCTFLGWSWGGLLAYEAARTLGNEVDVRMMAMVDVCDLGSEFAIGAKPRFRPGERGALHRDVQAWLQK
TAMRPEWDRLLSTMDADTYEQFLRFVGDEKDPLPTDGPDISSREHTFWVLIDNALIFRKHRLVPHDVPIYPWAADDSLNR
GLNLIDWRRLSPRARAAEIITGTNHLHMIGSPAFHSRLALRLKETEKDNA

Specific function: Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=587, Percent_Identity=21.4650766609881, Blast_Score=82, Evalue=4e-15,
Organism=Homo sapiens, GI42544132, Length=388, Percent_Identity=24.4845360824742, Blast_Score=81, Evalue=8e-15,
Organism=Homo sapiens, GI187761345, Length=497, Percent_Identity=22.9376257545272, Blast_Score=80, Evalue=2e-14,
Organism=Homo sapiens, GI187761343, Length=497, Percent_Identity=22.9376257545272, Blast_Score=80, Evalue=2e-14,
Organism=Homo sapiens, GI157311624, Length=476, Percent_Identity=24.5798319327731, Blast_Score=74, Evalue=1e-12,
Organism=Homo sapiens, GI157311622, Length=476, Percent_Identity=24.5798319327731, Blast_Score=74, Evalue=1e-12,
Organism=Homo sapiens, GI58082049, Length=480, Percent_Identity=24.5833333333333, Blast_Score=73, Evalue=1e-12,
Organism=Escherichia coli, GI1786801, Length=1188, Percent_Identity=25.0841750841751, Blast_Score=249, Evalue=6e-67,
Organism=Escherichia coli, GI145693145, Length=516, Percent_Identity=23.2558139534884, Blast_Score=104, Evalue=5e-23,
Organism=Escherichia coli, GI1788107, Length=571, Percent_Identity=24.5183887915937, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17556356, Length=696, Percent_Identity=25.8620689655172, Blast_Score=153, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17550940, Length=451, Percent_Identity=24.390243902439, Blast_Score=123, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI32563687, Length=505, Percent_Identity=24.7524752475248, Blast_Score=110, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17538037, Length=543, Percent_Identity=23.0202578268877, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17559526, Length=381, Percent_Identity=24.4094488188976, Blast_Score=73, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560308, Length=381, Percent_Identity=22.3097112860892, Blast_Score=72, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=771, Percent_Identity=26.3294422827497, Blast_Score=217, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6319699, Length=352, Percent_Identity=24.1477272727273, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24648676, Length=623, Percent_Identity=28.5714285714286, Blast_Score=170, Evalue=8e-42,
Organism=Drosophila melanogaster, GI21355181, Length=541, Percent_Identity=22.9205175600739, Blast_Score=95, Evalue=4e-19,
Organism=Drosophila melanogaster, GI18859661, Length=544, Percent_Identity=22.9779411764706, Blast_Score=94, Evalue=7e-19,
Organism=Drosophila melanogaster, GI19922652, Length=508, Percent_Identity=23.2283464566929, Blast_Score=85, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24581924, Length=359, Percent_Identity=24.5125348189415, Blast_Score=73, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 147044; Mature: 147044

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQITNFADARPTDAVDAVFESFPLTIAQKRIWSLEQIGNYTVFPDQVIGLRLSAAIDV
CCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCEEECCCHHHCEEEEEEECH
ETIAGACRALVADNPSLASRFRRLAGGRIEQYRGASSAVPVEILGTDGAALSEPDALAAR
HHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHH
KAFRDKRFDLLEGPGARIQIIRLADGQSLLTIVLHPIICDDREKSVLARSLARILDGEPA
HHHHHCCCHHHCCCCCEEEEEEECCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
GDMQPVEIAAGTREADWLETDEARQALAYWRDAIGLDYAASTFPTRFNSGGLAGVARAEH
CCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCHHHHCCC
RFSIEPDLWSKLERHAGRKDVQVERVLHAAFCALLARYSGNYALLTGLLVARPRTEHFAS
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHH
RGRAEQVLPLVLSLTSRHSLDDVVAAISSVTQEGLARLVPLERITQELVVDEAAAQEAVV
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
KALFEFREPYPVPRQATNLEPSGARADSELSLVIEARADGAAYGLIDYAGDLYDGALIAR
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEHHHHCCCHHHHHHHHH
VARHFCLVLEQIVAKPDLRIKDIELMGSDELDWLSAPYEDDVVNDDRPVHELISAHSRRT
HHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
PDKTAIVYGDEEWSHGWLEASTNRLGHRLRQLGVRAEVTVAIFIKRSPEAIVGILATLKA
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHC
GGAYIPVEPGHPPVRNHHILRDGDVKIVLTHSWLRHRLPEELDATVLELDKLDLDGEPDT
CCEEEECCCCCCCCCCCCEEECCCEEEEEECHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
PLCVPTHKDQLAYVMYTSGSTGLPKGVAVEHGPLTHHLQNTSRVYGMSSESRELPFLPFS
CEEECCCCCCEEEEEEECCCCCCCCCCEECCCCCHHHHCCCHHEECCCCCCCCCCEECCC
SDGGHERWMNPLMEGGSIILPDQPLWTPEETLTAMRKHGANNASIPTTYLQQLAEWADIT
CCCCHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
DGAPPMRLYSFGGEGLAQSTFDLLSRALKSEWLINGYGPTETIMTPMVWKVRAGTKFQGV
CCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCEEECCCCHHHHHCCCEEEEECCCEECCH
YAPLGRAVGLRRVYVLDPDLNLCPIGVTGELYIGGEGIARGYLGKADTTADRFIPDPFSK
HHHHHHHCCCEEEEEECCCCCEEEECCCCEEEECCCCHHCCCCCCCCCCHHHCCCCCCCC
EGGRLYRSGDLTRWREDGTVEFVGRVDHQVKLRGYRIELGEIEAALLQQPGVGEALVVLR
CCCEEEECCCCCEECCCCCEEEEECCCCEEEEEEEEEEHHHHHHHHHCCCCCCCEEEEEE
DDDAGGEKALVAYVVPKKDERLDVETVRAGLERSLPSYMVPASVVELEKMPTNPNSKLDR
CCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHH
FALPAPQPVKRAIVEPATALEEEVLDVWRQVLKLEAISVEDNFFAIGGNSLGAIRILTQL
CCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCCHHHHHHHHH
RQRRPKVPLTVADIFNNPTIRAFAGVMEQGEERDLSEVIVLRASGAKPRLYCFPGLLVST
HHHCCCCCEEHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEECCCHHHHH
REYVKLVDYLGADQPATGFICHSLSEKKEVGAPIEEIIEPYVDYIRTHSKGAPCTFLGWS
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCC
WGGLLAYEAARTLGNEVDVRMMAMVDVCDLGSEFAIGAKPRFRPGERGALHRDVQAWLQK
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCHHHHHHHHHHH
TAMRPEWDRLLSTMDADTYEQFLRFVGDEKDPLPTDGPDISSREHTFWVLIDNALIFRKH
HCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEHHC
RLVPHDVPIYPWAADDSLNRGLNLIDWRRLSPRARAAEIITGTNHLHMIGSPAFHSRLAL
CCCCCCCCCCCCCCCCHHHCCCCCEECCCCCCHHHHHHEEECCCCEEEECCCHHHHHHHH
RLKETEKDNA
HHHCCCCCCC
>Mature Secondary Structure
MNKQITNFADARPTDAVDAVFESFPLTIAQKRIWSLEQIGNYTVFPDQVIGLRLSAAIDV
CCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCEEECCCHHHCEEEEEEECH
ETIAGACRALVADNPSLASRFRRLAGGRIEQYRGASSAVPVEILGTDGAALSEPDALAAR
HHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHH
KAFRDKRFDLLEGPGARIQIIRLADGQSLLTIVLHPIICDDREKSVLARSLARILDGEPA
HHHHHCCCHHHCCCCCEEEEEEECCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
GDMQPVEIAAGTREADWLETDEARQALAYWRDAIGLDYAASTFPTRFNSGGLAGVARAEH
CCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCHHHHCCC
RFSIEPDLWSKLERHAGRKDVQVERVLHAAFCALLARYSGNYALLTGLLVARPRTEHFAS
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHH
RGRAEQVLPLVLSLTSRHSLDDVVAAISSVTQEGLARLVPLERITQELVVDEAAAQEAVV
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
KALFEFREPYPVPRQATNLEPSGARADSELSLVIEARADGAAYGLIDYAGDLYDGALIAR
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEHHHHCCCHHHHHHHHH
VARHFCLVLEQIVAKPDLRIKDIELMGSDELDWLSAPYEDDVVNDDRPVHELISAHSRRT
HHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
PDKTAIVYGDEEWSHGWLEASTNRLGHRLRQLGVRAEVTVAIFIKRSPEAIVGILATLKA
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHC
GGAYIPVEPGHPPVRNHHILRDGDVKIVLTHSWLRHRLPEELDATVLELDKLDLDGEPDT
CCEEEECCCCCCCCCCCCEEECCCEEEEEECHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
PLCVPTHKDQLAYVMYTSGSTGLPKGVAVEHGPLTHHLQNTSRVYGMSSESRELPFLPFS
CEEECCCCCCEEEEEEECCCCCCCCCCEECCCCCHHHHCCCHHEECCCCCCCCCCEECCC
SDGGHERWMNPLMEGGSIILPDQPLWTPEETLTAMRKHGANNASIPTTYLQQLAEWADIT
CCCCHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
DGAPPMRLYSFGGEGLAQSTFDLLSRALKSEWLINGYGPTETIMTPMVWKVRAGTKFQGV
CCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCEEECCCCHHHHHCCCEEEEECCCEECCH
YAPLGRAVGLRRVYVLDPDLNLCPIGVTGELYIGGEGIARGYLGKADTTADRFIPDPFSK
HHHHHHHCCCEEEEEECCCCCEEEECCCCEEEECCCCHHCCCCCCCCCCHHHCCCCCCCC
EGGRLYRSGDLTRWREDGTVEFVGRVDHQVKLRGYRIELGEIEAALLQQPGVGEALVVLR
CCCEEEECCCCCEECCCCCEEEEECCCCEEEEEEEEEEHHHHHHHHHCCCCCCCEEEEEE
DDDAGGEKALVAYVVPKKDERLDVETVRAGLERSLPSYMVPASVVELEKMPTNPNSKLDR
CCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHH
FALPAPQPVKRAIVEPATALEEEVLDVWRQVLKLEAISVEDNFFAIGGNSLGAIRILTQL
CCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCCHHHHHHHHH
RQRRPKVPLTVADIFNNPTIRAFAGVMEQGEERDLSEVIVLRASGAKPRLYCFPGLLVST
HHHCCCCCEEHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEECCCHHHHH
REYVKLVDYLGADQPATGFICHSLSEKKEVGAPIEEIIEPYVDYIRTHSKGAPCTFLGWS
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCC
WGGLLAYEAARTLGNEVDVRMMAMVDVCDLGSEFAIGAKPRFRPGERGALHRDVQAWLQK
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCHHHHHHHHHHH
TAMRPEWDRLLSTMDADTYEQFLRFVGDEKDPLPTDGPDISSREHTFWVLIDNALIFRKH
HCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEHHC
RLVPHDVPIYPWAADDSLNRGLNLIDWRRLSPRARAAEIITGTNHLHMIGSPAFHSRLAL
CCCCCCCCCCCCCCCCHHHCCCCCEECCCCCCHHHHHHEEECCCCEEEECCCHHHHHHHH
RLKETEKDNA
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352938; 10801488 [H]