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The map label for this gene is ribE [H]

Identifier: 190571514

GI number: 190571514

Start: 1217353

End: 1217949

Strand: Reverse

Name: ribE [H]

Synonym: WPa_1133

Alternate gene names: 190571514

Gene position: 1217949-1217353 (Counterclockwise)

Preceding gene: 190571515

Following gene: 190571513

Centisome position: 82.16

GC content: 32.5

Gene sequence:

>597_bases
ATGTTTAAAGGAATTATCCAAGATATTGGCACTATAACTGATATCACTATCCACCCTAACTCTGATCAAATCTTCCATAT
TGAGACACAAAATTTATCCTCTATAAACAAAGGAGATTCAATATCCTGCTCCGGAGTGTGTTTAACTGTTGTCGACATAA
TGAGCAATGTATTCACAGTTCAAGTATCTCAAGAAACTATGAAGGTTTCTAACTTAAATATGTGGAAAATAGGAAAAAAA
ATAAACCTAGAACAAGCAATGAAACTGAGTGACAGAATTGACGGCCACTTGGTTCAGGGTCATGTGGATGACACAACAGA
AATTTTAACAATCAATCAAAATTTAGAATCTCATGAAATCAGACTATCATGCCCACAAGAATTAATTAAATTTATTACAA
AAAAAGGTTCTGTAACGCTAGATGGAGTTTCCCTTACAGTAAATTCAGTTGTCGATCAAGAATTCACTGTGAATATAATT
CCCTATACATGGAAAAACACAACTTTTCAGCATAATAAAACAGGTAATTACCTAAATTTAGAAGTTGATATGATTGCCCG
GTACTTAGACCAGCTGATAAAATATCAATACAATTAA

Upstream 100 bases:

>100_bases
GAATATTCTGTAGAATCTATTGAGCAGATAAGTGAAAAAGATCTTCCTTTGCACATCTAACAAATAAGATCTTTTGTGAT
ATAATTATTTATTTTATTGC

Downstream 100 bases:

>100_bases
TTTTACAACTTTGTTATTTACAACTATTATATCTTGAAAATCATATAGATACAAAATATGTTTTTCGATAGCCTAATTAT
CTTTATTATTGTCTTGTGTG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MFKGIIQDIGTITDITIHPNSDQIFHIETQNLSSINKGDSISCSGVCLTVVDIMSNVFTVQVSQETMKVSNLNMWKIGKK
INLEQAMKLSDRIDGHLVQGHVDDTTEILTINQNLESHEIRLSCPQELIKFITKKGSVTLDGVSLTVNSVVDQEFTVNII
PYTWKNTTFQHNKTGNYLNLEVDMIARYLDQLIKYQYN

Sequences:

>Translated_198_residues
MFKGIIQDIGTITDITIHPNSDQIFHIETQNLSSINKGDSISCSGVCLTVVDIMSNVFTVQVSQETMKVSNLNMWKIGKK
INLEQAMKLSDRIDGHLVQGHVDDTTEILTINQNLESHEIRLSCPQELIKFITKKGSVTLDGVSLTVNSVVDQEFTVNII
PYTWKNTTFQHNKTGNYLNLEVDMIARYLDQLIKYQYN
>Mature_198_residues
MFKGIIQDIGTITDITIHPNSDQIFHIETQNLSSINKGDSISCSGVCLTVVDIMSNVFTVQVSQETMKVSNLNMWKIGKK
INLEQAMKLSDRIDGHLVQGHVDDTTEILTINQNLESHEIRLSCPQELIKFITKKGSVTLDGVSLTVNSVVDQEFTVNII
PYTWKNTTFQHNKTGNYLNLEVDMIARYLDQLIKYQYN

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=185, Percent_Identity=34.5945945945946, Blast_Score=116, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6319733, Length=207, Percent_Identity=34.2995169082126, Blast_Score=105, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22423; Mature: 22423

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKGIIQDIGTITDITIHPNSDQIFHIETQNLSSINKGDSISCSGVCLTVVDIMSNVFTV
CCCHHHHHCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCEECHHHHHHHHHHCCEEEE
QVSQETMKVSNLNMWKIGKKINLEQAMKLSDRIDGHLVQGHVDDTTEILTINQNLESHEI
EECHHHEEECCCCEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCCEE
RLSCPQELIKFITKKGSVTLDGVSLTVNSVVDQEFTVNIIPYTWKNTTFQHNKTGNYLNL
EEECHHHHHHHHHCCCCEEECCEEEEEEHHCCCCEEEEEEEEEECCCEEEECCCCCEEEE
EVDMIARYLDQLIKYQYN
EHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFKGIIQDIGTITDITIHPNSDQIFHIETQNLSSINKGDSISCSGVCLTVVDIMSNVFTV
CCCHHHHHCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCEECHHHHHHHHHHCCEEEE
QVSQETMKVSNLNMWKIGKKINLEQAMKLSDRIDGHLVQGHVDDTTEILTINQNLESHEI
EECHHHEEECCCCEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCCEE
RLSCPQELIKFITKKGSVTLDGVSLTVNSVVDQEFTVNIIPYTWKNTTFQHNKTGNYLNL
EEECHHHHHHHHHCCCCEEECCEEEEEEHHCCCCEEEEEEEEEECCCEEEECCCCCEEEE
EVDMIARYLDQLIKYQYN
EHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]