Click here to switch to the map view.

The map label for this gene is nuoG [H]

Identifier: 190571479

GI number: 190571479

Start: 1167401

End: 1169449

Strand: Direct

Name: nuoG [H]

Synonym: WPa_1094

Alternate gene names: 190571479

Gene position: 1167401-1169449 (Clockwise)

Preceding gene: 190571478

Following gene: 190571480

Centisome position: 78.75

GC content: 37.63

Gene sequence:

>2049_bases
GTGGTTAAAGTTACTATTAATTCTAAGGAATGTGAAGTAGAGCATGGGCTCACTATAATTCAAGCTTGTGAAGTTGTGGG
CGTTGAAGTTCCGCGGTTTTGTTATCATGAGCGTTTAGCAATTGCTGGTAACTGCAGAATGTGTTTGGTTGAAGTTGAGG
GTGGCCCTCCAAAACCAGTAGCTTCTTGTGCAATGCCAGTTGCAGAGGGTATGGTTATTCACACGGATACTCCCAAGGTA
AAAAAGGCGCGTGAAGGAGTGCTCGAATTTTTACTAATTAATCATCCACTTGATTGTCCAATTTGTGATCAAGGTGGTGA
GTGCGATTTGCAAGATATAACAATGGCTTATGGGAAAGGAATAAGCAGACTTGATGAGCATAAAAGAGCTGTGCCAAAAA
AACATTTTGGTCCACTGATTGGAACTGCAATGAATAGATGCATTCATTGTACTCGATGTGTTAGATTTTTGTCCGATGTT
GCAGGTACAAATGAACTTGGAGGAATTGGCAGGGGAGAAAATATAGAGATTAGTACTTACATAAAAAGGCATATTAGCTC
TGAATTATCTGGGAATATTATAGATCTCTGCCCGGTAGGGGCTTTAACTTCAAAGCCTTACTCCTTTACAGCGCGTCCAT
GGGAGCTATCACATTGTGAGACTATAGATGTGCTAGATGCTGTGGGAAGTAGCATTAGAGTTGATTATCGTGGCCTGGAA
GTTATGCGAATATTACCAAGGCTGAGCGAAGAGGTAAATGAAGAATGGATATCAGATAAAACCCGTTTTGCCTATGATGG
ACTAAAAGTTCAGCGTCTTGATCAACCTTATGTAAAAAAAGATGGTAAATTAGCCCCAGTTGATTGGAATGAAGCACTAA
CTGTTGCTGCAAAGAAATTAAAAAATACAAAATCAAATAAAATAGCTGCAATTGCAGGTGATTTAGCAGATTGTGAGTCT
ATGCTTCTACTCAAAGAAGTGATGCAGAAGCTCGGCTCGGGGAATATAGACTGTAGGCAAGATGGAGCAAAGCTTATACC
AAATAATCGTGGGTCATATGTATTCAACACCACTATTGAGGGTATAGAAAATGCAGATTTATGTCTGCTTATAAATACAA
ATCCAAGAATAGAAGCACCAATAATTAACGCAAGATTGAGAAAGAGATATTTACAAGGTAATTTCACTATTGCAAATATT
GGTCCTAATCTTGAATATCTATATAATGTTGAAAGATTAGGTGATGGTCCAAACGTTCTAAAAGAAATAGAAGAGGGAAA
TCACAAATTCTGCGAGTTACTGAGTGCGGCTCAGAACCCTATGCTAATTATCGGTCAAGATGCATTAATAAGAGATGATT
CTGAATCAGTTTTAGCTCTAGCTGGCAAAATTGCAGAAAAATTTAACATGATCAGAGATGACTGGAATGGCTTTAACGTA
CTGCATAAGGCTGCAGCAAGGGTTGGTGGACTCGATATTGGATTCGTTCCTAGCAAAGGTGGAAAAGACATTAATCAGAT
GCTAAAACAGGCAGAAAGTGGTGAGATAGAAGTAGTTTATCTTCTTGGCGCAGATGAAATTGATATATCAAAGTTAGAAA
GTACATTTGTAATTTATCAAGGCCACCATGGTGATAGGGGAGCGCATATAGCAGATGTCATTCTACCTGGAGCTGCATAC
ACAGAAAAATATGCAACTTATGTAAATACTGAAGGGCGAGTACAGAGAACAAATTTAGCTGTTTTTCCTCCTGGTGAAGC
AAAGGAAGATTGGTTGATTATAAAAAATTTATCCCAATATTTGGGCCTTTCCTTACTATATGATAATTTATTTGATGTGA
GGAAGAAATTATACACTATTGGTCCACAGTTTAGAGATGCTGACCAAGTGGTGAAAAACAAATGGGTACCAATTACCTGT
GATGAAATAAAATTAAGTAATATCTCTTTCACTCTAAAAAAGTGTAATTTTTATATGACAGACTCAATAAGTCGCGCTTC
AAAAATAATGGCAGATTGTACTAAGGATTTTTATGAACACTCTACTTAA

Upstream 100 bases:

>100_bases
ATTCACGTATGAACTATATGTCTGCTCAATACGATAACGGCAATCTAGTTGAAGATGAGGTAAGCGGCAATCCTATAAAG
TGGGAAGCTGTATAGTAGTT

Downstream 100 bases:

>100_bases
TATTTTATTTATTCTAACACCATTATTACTAATAACTCTGGTATATTTTCAACGAAAATTAAACTCTATATTTTTGTGTA
AAGAACAAAATACATTAGAA

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 682; Mature: 682

Protein sequence:

>682_residues
MVKVTINSKECEVEHGLTIIQACEVVGVEVPRFCYHERLAIAGNCRMCLVEVEGGPPKPVASCAMPVAEGMVIHTDTPKV
KKAREGVLEFLLINHPLDCPICDQGGECDLQDITMAYGKGISRLDEHKRAVPKKHFGPLIGTAMNRCIHCTRCVRFLSDV
AGTNELGGIGRGENIEISTYIKRHISSELSGNIIDLCPVGALTSKPYSFTARPWELSHCETIDVLDAVGSSIRVDYRGLE
VMRILPRLSEEVNEEWISDKTRFAYDGLKVQRLDQPYVKKDGKLAPVDWNEALTVAAKKLKNTKSNKIAAIAGDLADCES
MLLLKEVMQKLGSGNIDCRQDGAKLIPNNRGSYVFNTTIEGIENADLCLLINTNPRIEAPIINARLRKRYLQGNFTIANI
GPNLEYLYNVERLGDGPNVLKEIEEGNHKFCELLSAAQNPMLIIGQDALIRDDSESVLALAGKIAEKFNMIRDDWNGFNV
LHKAAARVGGLDIGFVPSKGGKDINQMLKQAESGEIEVVYLLGADEIDISKLESTFVIYQGHHGDRGAHIADVILPGAAY
TEKYATYVNTEGRVQRTNLAVFPPGEAKEDWLIIKNLSQYLGLSLLYDNLFDVRKKLYTIGPQFRDADQVVKNKWVPITC
DEIKLSNISFTLKKCNFYMTDSISRASKIMADCTKDFYEHST

Sequences:

>Translated_682_residues
MVKVTINSKECEVEHGLTIIQACEVVGVEVPRFCYHERLAIAGNCRMCLVEVEGGPPKPVASCAMPVAEGMVIHTDTPKV
KKAREGVLEFLLINHPLDCPICDQGGECDLQDITMAYGKGISRLDEHKRAVPKKHFGPLIGTAMNRCIHCTRCVRFLSDV
AGTNELGGIGRGENIEISTYIKRHISSELSGNIIDLCPVGALTSKPYSFTARPWELSHCETIDVLDAVGSSIRVDYRGLE
VMRILPRLSEEVNEEWISDKTRFAYDGLKVQRLDQPYVKKDGKLAPVDWNEALTVAAKKLKNTKSNKIAAIAGDLADCES
MLLLKEVMQKLGSGNIDCRQDGAKLIPNNRGSYVFNTTIEGIENADLCLLINTNPRIEAPIINARLRKRYLQGNFTIANI
GPNLEYLYNVERLGDGPNVLKEIEEGNHKFCELLSAAQNPMLIIGQDALIRDDSESVLALAGKIAEKFNMIRDDWNGFNV
LHKAAARVGGLDIGFVPSKGGKDINQMLKQAESGEIEVVYLLGADEIDISKLESTFVIYQGHHGDRGAHIADVILPGAAY
TEKYATYVNTEGRVQRTNLAVFPPGEAKEDWLIIKNLSQYLGLSLLYDNLFDVRKKLYTIGPQFRDADQVVKNKWVPITC
DEIKLSNISFTLKKCNFYMTDSISRASKIMADCTKDFYEHST
>Mature_682_residues
MVKVTINSKECEVEHGLTIIQACEVVGVEVPRFCYHERLAIAGNCRMCLVEVEGGPPKPVASCAMPVAEGMVIHTDTPKV
KKAREGVLEFLLINHPLDCPICDQGGECDLQDITMAYGKGISRLDEHKRAVPKKHFGPLIGTAMNRCIHCTRCVRFLSDV
AGTNELGGIGRGENIEISTYIKRHISSELSGNIIDLCPVGALTSKPYSFTARPWELSHCETIDVLDAVGSSIRVDYRGLE
VMRILPRLSEEVNEEWISDKTRFAYDGLKVQRLDQPYVKKDGKLAPVDWNEALTVAAKKLKNTKSNKIAAIAGDLADCES
MLLLKEVMQKLGSGNIDCRQDGAKLIPNNRGSYVFNTTIEGIENADLCLLINTNPRIEAPIINARLRKRYLQGNFTIANI
GPNLEYLYNVERLGDGPNVLKEIEEGNHKFCELLSAAQNPMLIIGQDALIRDDSESVLALAGKIAEKFNMIRDDWNGFNV
LHKAAARVGGLDIGFVPSKGGKDINQMLKQAESGEIEVVYLLGADEIDISKLESTFVIYQGHHGDRGAHIADVILPGAAY
TEKYATYVNTEGRVQRTNLAVFPPGEAKEDWLIIKNLSQYLGLSLLYDNLFDVRKKLYTIGPQFRDADQVVKNKWVPITC
DEIKLSNISFTLKKCNFYMTDSISRASKIMADCTKDFYEHST

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=697, Percent_Identity=50.0717360114778, Blast_Score=695, Evalue=0.0,
Organism=Escherichia coli, GI145693161, Length=675, Percent_Identity=26.2222222222222, Blast_Score=211, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17565758, Length=703, Percent_Identity=46.9416785206259, Blast_Score=630, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32566231, Length=589, Percent_Identity=49.4057724957555, Blast_Score=578, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI193209088, Length=252, Percent_Identity=58.7301587301587, Blast_Score=322, Evalue=3e-88,
Organism=Drosophila melanogaster, GI24640559, Length=684, Percent_Identity=48.6842105263158, Blast_Score=634, Evalue=0.0,
Organism=Drosophila melanogaster, GI24640557, Length=684, Percent_Identity=48.6842105263158, Blast_Score=634, Evalue=0.0,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 75673; Mature: 75673

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVTINSKECEVEHGLTIIQACEVVGVEVPRFCYHERLAIAGNCRMCLVEVEGGPPKPV
CEEEEECCCCCCHHHCCHHHHHHHHHCCCCCHHHHHCCEEEECCCEEEEEEECCCCCCCH
ASCAMPVAEGMVIHTDTPKVKKAREGVLEFLLINHPLDCPICDQGGECDLQDITMAYGKG
HHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCC
ISRLDEHKRAVPKKHFGPLIGTAMNRCIHCTRCVRFLSDVAGTNELGGIGRGENIEISTY
HHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHH
IKRHISSELSGNIIDLCPVGALTSKPYSFTARPWELSHCETIDVLDAVGSSIRVDYRGLE
HHHHHHHHHCCCEEEECCCCCCCCCCCEECCCCCCCCCCCHHHHHHHCCCCEEEECCCHH
VMRILPRLSEEVNEEWISDKTRFAYDGLKVQRLDQPYVKKDGKLAPVDWNEALTVAAKKL
HHHHHHHHHHHHHHHHHCCCCEEEECCEEEEECCCCHHCCCCCCCCCCCCHHHHHHHHHH
KNTKSNKIAAIAGDLADCESMLLLKEVMQKLGSGNIDCRQDGAKLIPNNRGSYVFNTTIE
HCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEECCCCCEECCCCCCCEEEEEEEC
GIENADLCLLINTNPRIEAPIINARLRKRYLQGNFTIANIGPNLEYLYNVERLGDGPNVL
CCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEHHHCCCCHHHH
KEIEEGNHKFCELLSAAQNPMLIIGQDALIRDDSESVLALAGKIAEKFNMIRDDWNGFNV
HHHHCCCHHHHHHHHHCCCCEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
LHKAAARVGGLDIGFVPSKGGKDINQMLKQAESGEIEVVYLLGADEIDISKLESTFVIYQ
HHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCEEEEEE
GHHGDRGAHIADVILPGAAYTEKYATYVNTEGRVQRTNLAVFPPGEAKEDWLIIKNLSQY
CCCCCCCCEEEHEEECCCHHHHHHHHEECCCCCEEECEEEEECCCCCCCCEEEHHHHHHH
LGLSLLYDNLFDVRKKLYTIGPQFRDADQVVKNKWVPITCDEIKLSNISFTLKKCNFYMT
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCEEECCEEEEEEECCEEEC
DSISRASKIMADCTKDFYEHST
CCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVKVTINSKECEVEHGLTIIQACEVVGVEVPRFCYHERLAIAGNCRMCLVEVEGGPPKPV
CEEEEECCCCCCHHHCCHHHHHHHHHCCCCCHHHHHCCEEEECCCEEEEEEECCCCCCCH
ASCAMPVAEGMVIHTDTPKVKKAREGVLEFLLINHPLDCPICDQGGECDLQDITMAYGKG
HHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCC
ISRLDEHKRAVPKKHFGPLIGTAMNRCIHCTRCVRFLSDVAGTNELGGIGRGENIEISTY
HHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHH
IKRHISSELSGNIIDLCPVGALTSKPYSFTARPWELSHCETIDVLDAVGSSIRVDYRGLE
HHHHHHHHHCCCEEEECCCCCCCCCCCEECCCCCCCCCCCHHHHHHHCCCCEEEECCCHH
VMRILPRLSEEVNEEWISDKTRFAYDGLKVQRLDQPYVKKDGKLAPVDWNEALTVAAKKL
HHHHHHHHHHHHHHHHHCCCCEEEECCEEEEECCCCHHCCCCCCCCCCCCHHHHHHHHHH
KNTKSNKIAAIAGDLADCESMLLLKEVMQKLGSGNIDCRQDGAKLIPNNRGSYVFNTTIE
HCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEECCCCCEECCCCCCCEEEEEEEC
GIENADLCLLINTNPRIEAPIINARLRKRYLQGNFTIANIGPNLEYLYNVERLGDGPNVL
CCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEHHHCCCCHHHH
KEIEEGNHKFCELLSAAQNPMLIIGQDALIRDDSESVLALAGKIAEKFNMIRDDWNGFNV
HHHHCCCHHHHHHHHHCCCCEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
LHKAAARVGGLDIGFVPSKGGKDINQMLKQAESGEIEVVYLLGADEIDISKLESTFVIYQ
HHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCEEEEEE
GHHGDRGAHIADVILPGAAYTEKYATYVNTEGRVQRTNLAVFPPGEAKEDWLIIKNLSQY
CCCCCCCCEEEHEEECCCHHHHHHHHEECCCCCEEECEEEEECCCCCCCCEEEHHHHHHH
LGLSLLYDNLFDVRKKLYTIGPQFRDADQVVKNKWVPITCDEIKLSNISFTLKKCNFYMT
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCEEECCEEEEEEECCEEEC
DSISRASKIMADCTKDFYEHST
CCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA