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The map label for this gene is putA [H]

Identifier: 190571475

GI number: 190571475

Start: 1161384

End: 1164524

Strand: Direct

Name: putA [H]

Synonym: WPa_1090

Alternate gene names: 190571475

Gene position: 1161384-1164524 (Clockwise)

Preceding gene: 190571474

Following gene: 190571476

Centisome position: 78.34

GC content: 36.71

Gene sequence:

>3141_bases
ATGATTAGCTCTATACAAGAACCTAATGAACTCAGAAAACGTTTACAAGGATTTTATCGTACTGATGAAAAAAGCTGTGT
ACGTTATCTCGTAGAAAAAGTAGAACTTTCGGTTGATTCGAAAAACAGAATTTACAATATTGCAAAACAAATTGTCGAAA
AGATTAGAGGTAGTAAATTAGGCATTATAGATTCTTTTATACAACAGTACTCACTTTCTAATGATGAAGGAGTAGCACTA
ATGTGTCTTGCTGAATCATTACTTAGAATACCAGACGATTACACAATAGATGAATTGATCAAAGATAAAATTGCCAACCA
AGAATGGAATAAACACTTGGGGCGTTCCTCTTCATTGTTTGTTAATGCTTCTACATGGAGTTTAATTATAGGAAGCAGTA
TATTAAGAAACAATGAAGAGGATTCAAAATTCTATAACATAATTTCCAGGTTATTGAAAAATTTAGGAGAGCCAATAATT
CGCAAAGCGGTAAAACAAGCAATATCCATTCTTGGCAAGCATTTTATTGTTGGAGAAACTATAGAAAAAGCATTGGAAAG
TGTGAAATCAGATGACTACAGTAAGTATTTATGCTCTTTTGATATGCTTGGTGAATCTGCTTGCACAGTTGAGGATGCGG
AAGAGTATTTTAATTTATACATGCATGCAATAAAAGCCATAGGTGAATCTGCTGACATAAATGATTGCTTTAAATCTCAG
GGGGTTTCAATCAAATTGTCTTCGCTGCACTCACGTTATGAATTTAGCCAATTTGATAATATGGCTGAAGAACTGAGAAC
TAAAGTACTGGAACTTTGTCATGAAGCAAAAAAGTATAATATTTCATTGTGTATAGATGCAGAAGAATCAGAAAGGCTTG
AGATGTCGCTCGTGTTATTTGAACAGTTGCGTCTTGATGAGTCACTTTCTGAGTGGGAAGGGCTTGGTCTAGCTGTGCAA
GCGTATCAAAAACGTGCTTTGTCTGTTCTTGATTTTGTTGAAGATGTTGCCATTCGATCAAAGCATAAGGTTATGGTGAG
ACTTGTGAAAGGAGCATATTGGGACTCGGAAATCAAGCGCACACAAGAATTAGGGTTAATTGGTTATCCGGTGTTTACTA
GAAAAAGCCACACAGATGTATGCTACCTTGCCTGTGCGCAGAAACTTTTAAGCAAAGAGAATCACTTTTATCCATGTTTT
GGAACTCATAATGCTTATACTTTTGCTACTATAATAGAGCTTGCCGATAAAAATCATCCTGGGTTTGAGTTTCAGCGCTT
ACATGGAATGGGTAAAAGTTTGTATGATTATGCAATTTCAGAACTTGCAACAAGCATCAATTGTCGTATATATGCACCAG
TTGGTAAACATAGTGATTTATTGCCATACCTTATTAGGCGTCTTCTTGAAAATGGAGCTAATAGCTCGTTTGTCAATCAA
GTAAATGATTCTGACGTTAAAATTGAAGAATTAGTCTCAGATCCATTAGAAAAAGTAAAAAGCTTAGAATATGAGCCTCA
TCCAAGCATTCCGTTGCCACGAGATATTTTTGGAGAGGAAAGAAAAAACTCCTTGGGAATGGATATTAGCGATTCAATTG
CAGTTTCACAATTTGCAAATGATGTAAGGGAATTTAGTGAAAAGAAATGGCAGGTTGGCCCAATAATTGATGGAGAGTCG
TTTCTTGACAGTGCGGAATTTACCGAAGTAGTGAATCCTGCACATTTGGAAAATGTAATTGGGGAAGTGTCAAGTGCAAC
AAGTGCTCATGCTTTAAATGCTCTTGAAATAGCACATAGTGCTTTTACTAAGTGGCAGAATGTTTCAGCAGAAGAGCGCG
CTAAATGCCTTGAAAAAGCTGCAGATTTGCTTGAGGAAAGGATGAAAGAGTTAATTTATATTCTGATTGTAGAAGCAGGA
AAAATTTTATCCGATGCAATAGCAGAAGTAAGAGAGGCAATCGACTTTTTGCGCTATTATGCAATGATAGCAAAAAATGA
ACTGAATGACTGGAAAAAATTGCCAGGTCCAACAGGTGAAGATAACTTCATCTTTTTTGAAGGCAGAGGAGTTTTCTTAT
GCATATCACCGTGGAATTTTCCACTCGCTATCTTCATTGGACAGGTTTCAGCTGCACTTGCAGCAGGTAATGCAGTGCTG
GCAAAACCGGCAGAGCAAACGCCGATTATTGCCTATGAAGCCGTTAAGATACTACACGAAGCTGGAATACCAAAAAATGT
GCTACACCTTATTCCAGGGGATGGTTGGTATTTAGGTAAAACATTAGTACCAGATAATAGAATTTCCGGTGTAGCTTTTA
CTGGTTCAACACAAACTGCTCAAATAATTAATCGAATGCTTGCTAGTAGAGATGGTCCTATTGTGCCACTTATCGCTGAG
ACTGGTGGATTAAATGCTATGATTGTTGATAGTTCTGCTCTTTTAGAGCAGGTAACTAAGGATGTTTTAATTTCTGCATT
TCGCAGTGGCGGTCAACGTTGTTCTGCTCTCAGAGTGCTATTTATTCAAGAAGATATAGCAGAAAAACAGGTAAAAATGA
TATGCAATGCAGCTCAAGAACTAAAGATAGGTGACCCAATACAACTGAGCACAGATATTGGTCCAATAATTGACAAAGCA
TCTATTGATATGCTCACTAAACATACGGAAAAAATATCAAGGGATGAAGATTCAAACCTTTTGTTCAAGGTACCAATGGA
TACAAATTCTTATAATGGTTATTTCTTTCCTCCGTACATTTATGAGATACAAAAAATTTCGCAATTAAAGCAAGAAGTGT
TTGGGCCTATTTTACATATCATACGTTTTAATAAGTCGCAGTTAAATGAAGTTATAAGTGATATAAACAATACAGGATAT
GGACTTACGTTTTCTTTGCAAAGCCGTGTACAAAGTCAGATCGCTTTAATAAGCAAGAAAATATCAGTTGGAAATGTATA
CATCAATCGCAATCAAATAGGTGCAGCAGTTGGAACACAACCATTTGGCGGTAGAGGACTGTCAGGTACCGGACCAAAAG
CTGGTGGTCCTAATTATCTGCAACGTTTTTCTATAGAAAAGGTTGTAAGTGTCAACACTACAGCATGTGGCGGTAACATT
AAACTTGCGTGTTTGGATTGA

Upstream 100 bases:

>100_bases
TTTTAGCTCCAGCCCTGGTCCTTTTAAATAATGATTTGTTCTATGCGAAGTTATGATATAATTTTACCTTACATATAGTA
AAGGTGTTTTATAGATAATT

Downstream 100 bases:

>100_bases
TTTGCAATTTCTAAATTGGAAGTCCGTGCAGTTGTGTATGCAGTACTAAAACCTAAAACTCATACATTGAAAGGATAGTT
GTGATTCTAAGGAGGCTTCA

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1046; Mature: 1046

Protein sequence:

>1046_residues
MISSIQEPNELRKRLQGFYRTDEKSCVRYLVEKVELSVDSKNRIYNIAKQIVEKIRGSKLGIIDSFIQQYSLSNDEGVAL
MCLAESLLRIPDDYTIDELIKDKIANQEWNKHLGRSSSLFVNASTWSLIIGSSILRNNEEDSKFYNIISRLLKNLGEPII
RKAVKQAISILGKHFIVGETIEKALESVKSDDYSKYLCSFDMLGESACTVEDAEEYFNLYMHAIKAIGESADINDCFKSQ
GVSIKLSSLHSRYEFSQFDNMAEELRTKVLELCHEAKKYNISLCIDAEESERLEMSLVLFEQLRLDESLSEWEGLGLAVQ
AYQKRALSVLDFVEDVAIRSKHKVMVRLVKGAYWDSEIKRTQELGLIGYPVFTRKSHTDVCYLACAQKLLSKENHFYPCF
GTHNAYTFATIIELADKNHPGFEFQRLHGMGKSLYDYAISELATSINCRIYAPVGKHSDLLPYLIRRLLENGANSSFVNQ
VNDSDVKIEELVSDPLEKVKSLEYEPHPSIPLPRDIFGEERKNSLGMDISDSIAVSQFANDVREFSEKKWQVGPIIDGES
FLDSAEFTEVVNPAHLENVIGEVSSATSAHALNALEIAHSAFTKWQNVSAEERAKCLEKAADLLEERMKELIYILIVEAG
KILSDAIAEVREAIDFLRYYAMIAKNELNDWKKLPGPTGEDNFIFFEGRGVFLCISPWNFPLAIFIGQVSAALAAGNAVL
AKPAEQTPIIAYEAVKILHEAGIPKNVLHLIPGDGWYLGKTLVPDNRISGVAFTGSTQTAQIINRMLASRDGPIVPLIAE
TGGLNAMIVDSSALLEQVTKDVLISAFRSGGQRCSALRVLFIQEDIAEKQVKMICNAAQELKIGDPIQLSTDIGPIIDKA
SIDMLTKHTEKISRDEDSNLLFKVPMDTNSYNGYFFPPYIYEIQKISQLKQEVFGPILHIIRFNKSQLNEVISDINNTGY
GLTFSLQSRVQSQIALISKKISVGNVYINRNQIGAAVGTQPFGGRGLSGTGPKAGGPNYLQRFSIEKVVSVNTTACGGNI
KLACLD

Sequences:

>Translated_1046_residues
MISSIQEPNELRKRLQGFYRTDEKSCVRYLVEKVELSVDSKNRIYNIAKQIVEKIRGSKLGIIDSFIQQYSLSNDEGVAL
MCLAESLLRIPDDYTIDELIKDKIANQEWNKHLGRSSSLFVNASTWSLIIGSSILRNNEEDSKFYNIISRLLKNLGEPII
RKAVKQAISILGKHFIVGETIEKALESVKSDDYSKYLCSFDMLGESACTVEDAEEYFNLYMHAIKAIGESADINDCFKSQ
GVSIKLSSLHSRYEFSQFDNMAEELRTKVLELCHEAKKYNISLCIDAEESERLEMSLVLFEQLRLDESLSEWEGLGLAVQ
AYQKRALSVLDFVEDVAIRSKHKVMVRLVKGAYWDSEIKRTQELGLIGYPVFTRKSHTDVCYLACAQKLLSKENHFYPCF
GTHNAYTFATIIELADKNHPGFEFQRLHGMGKSLYDYAISELATSINCRIYAPVGKHSDLLPYLIRRLLENGANSSFVNQ
VNDSDVKIEELVSDPLEKVKSLEYEPHPSIPLPRDIFGEERKNSLGMDISDSIAVSQFANDVREFSEKKWQVGPIIDGES
FLDSAEFTEVVNPAHLENVIGEVSSATSAHALNALEIAHSAFTKWQNVSAEERAKCLEKAADLLEERMKELIYILIVEAG
KILSDAIAEVREAIDFLRYYAMIAKNELNDWKKLPGPTGEDNFIFFEGRGVFLCISPWNFPLAIFIGQVSAALAAGNAVL
AKPAEQTPIIAYEAVKILHEAGIPKNVLHLIPGDGWYLGKTLVPDNRISGVAFTGSTQTAQIINRMLASRDGPIVPLIAE
TGGLNAMIVDSSALLEQVTKDVLISAFRSGGQRCSALRVLFIQEDIAEKQVKMICNAAQELKIGDPIQLSTDIGPIIDKA
SIDMLTKHTEKISRDEDSNLLFKVPMDTNSYNGYFFPPYIYEIQKISQLKQEVFGPILHIIRFNKSQLNEVISDINNTGY
GLTFSLQSRVQSQIALISKKISVGNVYINRNQIGAAVGTQPFGGRGLSGTGPKAGGPNYLQRFSIEKVVSVNTTACGGNI
KLACLD
>Mature_1046_residues
MISSIQEPNELRKRLQGFYRTDEKSCVRYLVEKVELSVDSKNRIYNIAKQIVEKIRGSKLGIIDSFIQQYSLSNDEGVAL
MCLAESLLRIPDDYTIDELIKDKIANQEWNKHLGRSSSLFVNASTWSLIIGSSILRNNEEDSKFYNIISRLLKNLGEPII
RKAVKQAISILGKHFIVGETIEKALESVKSDDYSKYLCSFDMLGESACTVEDAEEYFNLYMHAIKAIGESADINDCFKSQ
GVSIKLSSLHSRYEFSQFDNMAEELRTKVLELCHEAKKYNISLCIDAEESERLEMSLVLFEQLRLDESLSEWEGLGLAVQ
AYQKRALSVLDFVEDVAIRSKHKVMVRLVKGAYWDSEIKRTQELGLIGYPVFTRKSHTDVCYLACAQKLLSKENHFYPCF
GTHNAYTFATIIELADKNHPGFEFQRLHGMGKSLYDYAISELATSINCRIYAPVGKHSDLLPYLIRRLLENGANSSFVNQ
VNDSDVKIEELVSDPLEKVKSLEYEPHPSIPLPRDIFGEERKNSLGMDISDSIAVSQFANDVREFSEKKWQVGPIIDGES
FLDSAEFTEVVNPAHLENVIGEVSSATSAHALNALEIAHSAFTKWQNVSAEERAKCLEKAADLLEERMKELIYILIVEAG
KILSDAIAEVREAIDFLRYYAMIAKNELNDWKKLPGPTGEDNFIFFEGRGVFLCISPWNFPLAIFIGQVSAALAAGNAVL
AKPAEQTPIIAYEAVKILHEAGIPKNVLHLIPGDGWYLGKTLVPDNRISGVAFTGSTQTAQIINRMLASRDGPIVPLIAE
TGGLNAMIVDSSALLEQVTKDVLISAFRSGGQRCSALRVLFIQEDIAEKQVKMICNAAQELKIGDPIQLSTDIGPIIDKA
SIDMLTKHTEKISRDEDSNLLFKVPMDTNSYNGYFFPPYIYEIQKISQLKQEVFGPILHIIRFNKSQLNEVISDINNTGY
GLTFSLQSRVQSQIALISKKISVGNVYINRNQIGAAVGTQPFGGRGLSGTGPKAGGPNYLQRFSIEKVVSVNTTACGGNI
KLACLD

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI238859541, Length=487, Percent_Identity=29.9794661190965, Blast_Score=196, Evalue=7e-50,
Organism=Homo sapiens, GI25777736, Length=487, Percent_Identity=29.9794661190965, Blast_Score=196, Evalue=8e-50,
Organism=Homo sapiens, GI25777734, Length=487, Percent_Identity=29.9794661190965, Blast_Score=196, Evalue=8e-50,
Organism=Homo sapiens, GI25777730, Length=470, Percent_Identity=29.7872340425532, Blast_Score=187, Evalue=6e-47,
Organism=Homo sapiens, GI25777724, Length=477, Percent_Identity=30.188679245283, Blast_Score=183, Evalue=7e-46,
Organism=Homo sapiens, GI153266822, Length=457, Percent_Identity=29.7592997811816, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI21361176, Length=457, Percent_Identity=30.4157549234136, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI25777732, Length=471, Percent_Identity=29.2993630573248, Blast_Score=181, Evalue=5e-45,
Organism=Homo sapiens, GI21614513, Length=471, Percent_Identity=29.5116772823779, Blast_Score=180, Evalue=5e-45,
Organism=Homo sapiens, GI115387104, Length=444, Percent_Identity=28.6036036036036, Blast_Score=180, Evalue=6e-45,
Organism=Homo sapiens, GI12007648, Length=485, Percent_Identity=28.0412371134021, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI238814322, Length=469, Percent_Identity=30.2771855010661, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI25777728, Length=430, Percent_Identity=30.2325581395349, Blast_Score=167, Evalue=4e-41,
Organism=Homo sapiens, GI4507229, Length=474, Percent_Identity=29.535864978903, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI25777721, Length=487, Percent_Identity=28.7474332648871, Blast_Score=153, Evalue=8e-37,
Organism=Homo sapiens, GI188035924, Length=475, Percent_Identity=26.5263157894737, Blast_Score=143, Evalue=1e-33,
Organism=Homo sapiens, GI310128103, Length=475, Percent_Identity=26.5263157894737, Blast_Score=141, Evalue=3e-33,
Organism=Homo sapiens, GI310128093, Length=475, Percent_Identity=26.5263157894737, Blast_Score=141, Evalue=4e-33,
Organism=Homo sapiens, GI25777726, Length=480, Percent_Identity=27.5, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI25952152, Length=480, Percent_Identity=26.4583333333333, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI11095441, Length=439, Percent_Identity=26.879271070615, Blast_Score=133, Evalue=1e-30,
Organism=Homo sapiens, GI310128091, Length=398, Percent_Identity=27.1356783919598, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI310128089, Length=329, Percent_Identity=27.355623100304, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI310128087, Length=293, Percent_Identity=27.6450511945392, Blast_Score=98, Evalue=4e-20,
Organism=Homo sapiens, GI206597441, Length=434, Percent_Identity=25.8064516129032, Blast_Score=97, Evalue=8e-20,
Organism=Homo sapiens, GI206597439, Length=434, Percent_Identity=25.8064516129032, Blast_Score=97, Evalue=8e-20,
Organism=Homo sapiens, GI22907049, Length=434, Percent_Identity=25.8064516129032, Blast_Score=97, Evalue=8e-20,
Organism=Homo sapiens, GI4502043, Length=433, Percent_Identity=25.635103926097, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI238814371, Length=433, Percent_Identity=25.635103926097, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI71773324, Length=334, Percent_Identity=26.9461077844311, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI301500698, Length=290, Percent_Identity=26.8965517241379, Blast_Score=94, Evalue=9e-19,
Organism=Homo sapiens, GI310128095, Length=316, Percent_Identity=26.8987341772152, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI310128097, Length=263, Percent_Identity=27.7566539923954, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI73695881, Length=337, Percent_Identity=26.7062314540059, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI73695879, Length=337, Percent_Identity=26.7062314540059, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI4557303, Length=430, Percent_Identity=24.4186046511628, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI73466520, Length=430, Percent_Identity=24.4186046511628, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI310128099, Length=243, Percent_Identity=26.3374485596708, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI310128101, Length=241, Percent_Identity=26.1410788381743, Blast_Score=78, Evalue=5e-14,
Organism=Escherichia coli, GI1787250, Length=1035, Percent_Identity=46.8599033816425, Blast_Score=946, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=475, Percent_Identity=29.4736842105263, Blast_Score=184, Evalue=3e-47,
Organism=Escherichia coli, GI1787684, Length=460, Percent_Identity=29.7826086956522, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI87081896, Length=502, Percent_Identity=28.8844621513944, Blast_Score=175, Evalue=1e-44,
Organism=Escherichia coli, GI1787715, Length=462, Percent_Identity=28.5714285714286, Blast_Score=161, Evalue=2e-40,
Organism=Escherichia coli, GI1787558, Length=475, Percent_Identity=27.3684210526316, Blast_Score=160, Evalue=5e-40,
Organism=Escherichia coli, GI1786504, Length=487, Percent_Identity=27.1047227926078, Blast_Score=157, Evalue=4e-39,
Organism=Escherichia coli, GI87082295, Length=441, Percent_Identity=27.6643990929705, Blast_Score=151, Evalue=3e-37,
Organism=Escherichia coli, GI1788042, Length=446, Percent_Identity=28.47533632287, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI87081926, Length=443, Percent_Identity=25.5079006772009, Blast_Score=127, Evalue=5e-30,
Organism=Escherichia coli, GI1787653, Length=361, Percent_Identity=23.5457063711911, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI133930964, Length=578, Percent_Identity=28.0276816608997, Blast_Score=186, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17534447, Length=465, Percent_Identity=30.3225806451613, Blast_Score=186, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI25143874, Length=443, Percent_Identity=29.3453724604966, Blast_Score=183, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI25143876, Length=443, Percent_Identity=29.3453724604966, Blast_Score=182, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI17562198, Length=467, Percent_Identity=30.406852248394, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI25144435, Length=460, Percent_Identity=29.5652173913043, Blast_Score=170, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI71995606, Length=457, Percent_Identity=28.2275711159737, Blast_Score=167, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI115532534, Length=406, Percent_Identity=30.5418719211823, Blast_Score=162, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI17551164, Length=486, Percent_Identity=27.7777777777778, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71995613, Length=407, Percent_Identity=28.2555282555283, Blast_Score=157, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI32564736, Length=413, Percent_Identity=30.0242130750605, Blast_Score=157, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17534119, Length=473, Percent_Identity=27.906976744186, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI115534176, Length=439, Percent_Identity=29.1571753986333, Blast_Score=153, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI71986308, Length=445, Percent_Identity=28.314606741573, Blast_Score=148, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI32564151, Length=408, Percent_Identity=28.4313725490196, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71990744, Length=300, Percent_Identity=30, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17564084, Length=432, Percent_Identity=25.462962962963, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25146391, Length=344, Percent_Identity=25.8720930232558, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI32566756, Length=344, Percent_Identity=25.8720930232558, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25146394, Length=344, Percent_Identity=25.8720930232558, Blast_Score=97, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6321826, Length=542, Percent_Identity=29.3357933579336, Blast_Score=192, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6320917, Length=496, Percent_Identity=31.0483870967742, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6323821, Length=476, Percent_Identity=29.8319327731092, Blast_Score=182, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6325196, Length=445, Percent_Identity=30.1123595505618, Blast_Score=178, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6323822, Length=475, Percent_Identity=28.4210526315789, Blast_Score=174, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6319478, Length=501, Percent_Identity=27.3453093812375, Blast_Score=173, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6324950, Length=453, Percent_Identity=28.0353200883002, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323757, Length=329, Percent_Identity=26.4437689969605, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281362580, Length=494, Percent_Identity=30.1619433198381, Blast_Score=202, Evalue=1e-51,
Organism=Drosophila melanogaster, GI62472918, Length=494, Percent_Identity=30.1619433198381, Blast_Score=202, Evalue=1e-51,
Organism=Drosophila melanogaster, GI62472926, Length=494, Percent_Identity=30.1619433198381, Blast_Score=202, Evalue=1e-51,
Organism=Drosophila melanogaster, GI62472936, Length=494, Percent_Identity=30.1619433198381, Blast_Score=202, Evalue=1e-51,
Organism=Drosophila melanogaster, GI21356737, Length=494, Percent_Identity=30.1619433198381, Blast_Score=202, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24585660, Length=491, Percent_Identity=29.7352342158859, Blast_Score=189, Evalue=9e-48,
Organism=Drosophila melanogaster, GI24668425, Length=492, Percent_Identity=30.2845528455285, Blast_Score=181, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24668417, Length=492, Percent_Identity=30.2845528455285, Blast_Score=181, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24668413, Length=492, Percent_Identity=30.2845528455285, Blast_Score=181, Evalue=3e-45,
Organism=Drosophila melanogaster, GI20129399, Length=460, Percent_Identity=29.7826086956522, Blast_Score=178, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24650465, Length=464, Percent_Identity=28.6637931034483, Blast_Score=154, Evalue=5e-37,
Organism=Drosophila melanogaster, GI28571806, Length=490, Percent_Identity=24.6938775510204, Blast_Score=153, Evalue=8e-37,
Organism=Drosophila melanogaster, GI28571802, Length=490, Percent_Identity=24.6938775510204, Blast_Score=152, Evalue=9e-37,
Organism=Drosophila melanogaster, GI28571800, Length=490, Percent_Identity=24.6938775510204, Blast_Score=152, Evalue=9e-37,
Organism=Drosophila melanogaster, GI28571798, Length=490, Percent_Identity=24.6938775510204, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI28571796, Length=490, Percent_Identity=24.6938775510204, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI28571794, Length=490, Percent_Identity=24.6938775510204, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24666674, Length=468, Percent_Identity=27.991452991453, Blast_Score=140, Evalue=6e-33,
Organism=Drosophila melanogaster, GI28574525, Length=517, Percent_Identity=23.4042553191489, Blast_Score=128, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24638876, Length=430, Percent_Identity=27.906976744186, Blast_Score=117, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24638878, Length=458, Percent_Identity=27.0742358078603, Blast_Score=117, Evalue=6e-26,
Organism=Drosophila melanogaster, GI45552499, Length=437, Percent_Identity=25.1716247139588, Blast_Score=97, Evalue=8e-20,
Organism=Drosophila melanogaster, GI281360299, Length=437, Percent_Identity=25.4004576659039, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281360297, Length=437, Percent_Identity=25.4004576659039, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281360295, Length=437, Percent_Identity=25.4004576659039, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24586250, Length=437, Percent_Identity=25.4004576659039, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281360303, Length=433, Percent_Identity=25.1732101616628, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281360301, Length=433, Percent_Identity=25.4041570438799, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281360293, Length=266, Percent_Identity=25.187969924812, Blast_Score=68, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 116714; Mature: 116714

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSIQEPNELRKRLQGFYRTDEKSCVRYLVEKVELSVDSKNRIYNIAKQIVEKIRGSKL
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
GIIDSFIQQYSLSNDEGVALMCLAESLLRIPDDYTIDELIKDKIANQEWNKHLGRSSSLF
HHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHCCCCCCEE
VNASTWSLIIGSSILRNNEEDSKFYNIISRLLKNLGEPIIRKAVKQAISILGKHFIVGET
EECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
IEKALESVKSDDYSKYLCSFDMLGESACTVEDAEEYFNLYMHAIKAIGESADINDCFKSQ
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCC
GVSIKLSSLHSRYEFSQFDNMAEELRTKVLELCHEAKKYNISLCIDAEESERLEMSLVLF
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHH
EQLRLDESLSEWEGLGLAVQAYQKRALSVLDFVEDVAIRSKHKVMVRLVKGAYWDSEIKR
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
TQELGLIGYPVFTRKSHTDVCYLACAQKLLSKENHFYPCFGTHNAYTFATIIELADKNHP
HHHCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEECEECCCCHHHHHHHHHHHCCCCC
GFEFQRLHGMGKSLYDYAISELATSINCRIYAPVGKHSDLLPYLIRRLLENGANSSFVNQ
CHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHC
VNDSDVKIEELVSDPLEKVKSLEYEPHPSIPLPRDIFGEERKNSLGMDISDSIAVSQFAN
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCHHHCCCCCCCCHHHHHHHHHH
DVREFSEKKWQVGPIIDGESFLDSAEFTEVVNPAHLENVIGEVSSATSAHALNALEIAHS
HHHHHHHCCEECCCCCCCHHHHCHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AFTKWQNVSAEERAKCLEKAADLLEERMKELIYILIVEAGKILSDAIAEVREAIDFLRYY
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMIAKNELNDWKKLPGPTGEDNFIFFEGRGVFLCISPWNFPLAIFIGQVSAALAAGNAVL
HHHHHHHHHHHHHCCCCCCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEE
AKPAEQTPIIAYEAVKILHEAGIPKNVLHLIPGDGWYLGKTLVPDNRISGVAFTGSTQTA
ECCCCCCCCHHHHHHHHHHHCCCCHHHHEEECCCCEEECCEECCCCCCCCEEEECCCHHH
QIINRMLASRDGPIVPLIAETGGLNAMIVDSSALLEQVTKDVLISAFRSGGQRCSALRVL
HHHHHHHHCCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FIQEDIAEKQVKMICNAAQELKIGDPIQLSTDIGPIIDKASIDMLTKHTEKISRDEDSNL
HHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCE
LFKVPMDTNSYNGYFFPPYIYEIQKISQLKQEVFGPILHIIRFNKSQLNEVISDINNTGY
EEEEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
GLTFSLQSRVQSQIALISKKISVGNVYINRNQIGAAVGTQPFGGRGLSGTGPKAGGPNYL
CEEEEHHHHHHHHHHHHHHHEEECEEEEECCCCCHHCCCCCCCCCCCCCCCCCCCCHHHH
QRFSIEKVVSVNTTACGGNIKLACLD
HHHHHHHHHEECCEECCCCEEEEEEC
>Mature Secondary Structure
MISSIQEPNELRKRLQGFYRTDEKSCVRYLVEKVELSVDSKNRIYNIAKQIVEKIRGSKL
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
GIIDSFIQQYSLSNDEGVALMCLAESLLRIPDDYTIDELIKDKIANQEWNKHLGRSSSLF
HHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHCCCCCCEE
VNASTWSLIIGSSILRNNEEDSKFYNIISRLLKNLGEPIIRKAVKQAISILGKHFIVGET
EECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
IEKALESVKSDDYSKYLCSFDMLGESACTVEDAEEYFNLYMHAIKAIGESADINDCFKSQ
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCC
GVSIKLSSLHSRYEFSQFDNMAEELRTKVLELCHEAKKYNISLCIDAEESERLEMSLVLF
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHH
EQLRLDESLSEWEGLGLAVQAYQKRALSVLDFVEDVAIRSKHKVMVRLVKGAYWDSEIKR
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
TQELGLIGYPVFTRKSHTDVCYLACAQKLLSKENHFYPCFGTHNAYTFATIIELADKNHP
HHHCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEECEECCCCHHHHHHHHHHHCCCCC
GFEFQRLHGMGKSLYDYAISELATSINCRIYAPVGKHSDLLPYLIRRLLENGANSSFVNQ
CHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHC
VNDSDVKIEELVSDPLEKVKSLEYEPHPSIPLPRDIFGEERKNSLGMDISDSIAVSQFAN
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCHHHCCCCCCCCHHHHHHHHHH
DVREFSEKKWQVGPIIDGESFLDSAEFTEVVNPAHLENVIGEVSSATSAHALNALEIAHS
HHHHHHHCCEECCCCCCCHHHHCHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AFTKWQNVSAEERAKCLEKAADLLEERMKELIYILIVEAGKILSDAIAEVREAIDFLRYY
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMIAKNELNDWKKLPGPTGEDNFIFFEGRGVFLCISPWNFPLAIFIGQVSAALAAGNAVL
HHHHHHHHHHHHHCCCCCCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEE
AKPAEQTPIIAYEAVKILHEAGIPKNVLHLIPGDGWYLGKTLVPDNRISGVAFTGSTQTA
ECCCCCCCCHHHHHHHHHHHCCCCHHHHEEECCCCEEECCEECCCCCCCCEEEECCCHHH
QIINRMLASRDGPIVPLIAETGGLNAMIVDSSALLEQVTKDVLISAFRSGGQRCSALRVL
HHHHHHHHCCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FIQEDIAEKQVKMICNAAQELKIGDPIQLSTDIGPIIDKASIDMLTKHTEKISRDEDSNL
HHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCE
LFKVPMDTNSYNGYFFPPYIYEIQKISQLKQEVFGPILHIIRFNKSQLNEVISDINNTGY
EEEEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
GLTFSLQSRVQSQIALISKKISVGNVYINRNQIGAAVGTQPFGGRGLSGTGPKAGGPNYL
CEEEEHHHHHHHHHHHHHHHEEECEEEEECCCCCHHCCCCCCCCCCCCCCCCCCCCHHHH
QRFSIEKVVSVNTTACGGNIKLACLD
HHHHHHHHHEECCEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]