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The map label for this gene is fabH [H]

Identifier: 190571413

GI number: 190571413

Start: 1090266

End: 1091222

Strand: Reverse

Name: fabH [H]

Synonym: WPa_1025

Alternate gene names: 190571413

Gene position: 1091222-1090266 (Counterclockwise)

Preceding gene: 190571414

Following gene: 190571412

Centisome position: 73.61

GC content: 36.15

Gene sequence:

>957_bases
TTGAGTAAAAGTTTCATATTGAGCACTGGTTCTTACCTACCAAAAAAAATTTTGAGTAATAACGAAATTGCATTGATAGT
TGAAACAAACGATGAATGGATACGGCAAAGAACAGGAATAGTTCAAAGACATATAGCAGATGAAGGAGAACTAACGTCAG
ATTTAGCTGTTAATGCAGCAAAAAATGCTATAGAAAAAGCGAAAATTTCAATAGATGAAATTGGTTTGATCATAGTTGCA
ACAACAACACCTGACAAAACTTTGCCTAGCTGTGCAACGATTGTACAAAGTAAGTTAAAATGTAAAAATGCATTTTCTTT
TGATGTACAAGCAGCATGCTCTGGTTTTATATATGCAGTTACAGTTGCTGATTCGCTCATAAAATCTCACAATAGAATAA
AATATGCGCTCGTTATTGGTGCTGAAATAATGTCTAGGATTGTTGACTGGGAAGATAGGTCAACTTGTGTACTCTTTGGT
GATAGTGCTGGTGCAGTGATAATAAAATCAGAAATGGGTAGCAGCGGCATCATATCAACAAACTTACACTCTGATGGCAA
TGTGGACATACTATGTACGAACGGAGGGGTATCCTCTACTCGTGATTCTGGAAAGATACTTATGAATGGAAGAGAAGTGT
TTAAACATGCAGTGGATAAGTTAACAGCCTCAGTAGAGGAAACTCTGAAATGCAATAATTTGAAAATCATTGATATTGAC
TGGTTAATTCCCCATCAAGCAAACATTCGTATTATTGAAGCAGTAGTAAAGAAATTAGATTTTCCTATAGAGAAAGTGAT
TAATACCGTTGATAAGCATGCAAACACCTCAGCAGCATCAATTCCACTGGCCTTAGACTATGCAATACAAGAATCAAAAA
TAAAATCAGGAAATCTGGTACTGCTGATTTCAATAGGTGCAGGCCTGACCTGGGGTTCTGTGTTACTGCGCTATTAA

Upstream 100 bases:

>100_bases
GGAAATTCTGATGCTATTTCTTTTGCTCACGCTATAAAATTTGCAGTAAATGCAATCAGTGAAAATTTGAACCAGAAGAT
AATTAACGGGGTAAGTCATA

Downstream 100 bases:

>100_bases
CCTCAGTTATGGATTAGAAAATAGATAAAAGTATAACTAAGAAGAGGGAAACAGGGTAAACTCGAGTATTTTAGTAATAA
TAAGAGGTTACCCATGAAGA

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MSKSFILSTGSYLPKKILSNNEIALIVETNDEWIRQRTGIVQRHIADEGELTSDLAVNAAKNAIEKAKISIDEIGLIIVA
TTTPDKTLPSCATIVQSKLKCKNAFSFDVQAACSGFIYAVTVADSLIKSHNRIKYALVIGAEIMSRIVDWEDRSTCVLFG
DSAGAVIIKSEMGSSGIISTNLHSDGNVDILCTNGGVSSTRDSGKILMNGREVFKHAVDKLTASVEETLKCNNLKIIDID
WLIPHQANIRIIEAVVKKLDFPIEKVINTVDKHANTSAASIPLALDYAIQESKIKSGNLVLLISIGAGLTWGSVLLRY

Sequences:

>Translated_318_residues
MSKSFILSTGSYLPKKILSNNEIALIVETNDEWIRQRTGIVQRHIADEGELTSDLAVNAAKNAIEKAKISIDEIGLIIVA
TTTPDKTLPSCATIVQSKLKCKNAFSFDVQAACSGFIYAVTVADSLIKSHNRIKYALVIGAEIMSRIVDWEDRSTCVLFG
DSAGAVIIKSEMGSSGIISTNLHSDGNVDILCTNGGVSSTRDSGKILMNGREVFKHAVDKLTASVEETLKCNNLKIIDID
WLIPHQANIRIIEAVVKKLDFPIEKVINTVDKHANTSAASIPLALDYAIQESKIKSGNLVLLISIGAGLTWGSVLLRY
>Mature_317_residues
SKSFILSTGSYLPKKILSNNEIALIVETNDEWIRQRTGIVQRHIADEGELTSDLAVNAAKNAIEKAKISIDEIGLIIVAT
TTPDKTLPSCATIVQSKLKCKNAFSFDVQAACSGFIYAVTVADSLIKSHNRIKYALVIGAEIMSRIVDWEDRSTCVLFGD
SAGAVIIKSEMGSSGIISTNLHSDGNVDILCTNGGVSSTRDSGKILMNGREVFKHAVDKLTASVEETLKCNNLKIIDIDW
LIPHQANIRIIEAVVKKLDFPIEKVINTVDKHANTSAASIPLALDYAIQESKIKSGNLVLLISIGAGLTWGSVLLRY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=315, Percent_Identity=48.5714285714286, Blast_Score=299, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34427; Mature: 34296

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSFILSTGSYLPKKILSNNEIALIVETNDEWIRQRTGIVQRHIADEGELTSDLAVNAA
CCCCEEEECCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
KNAIEKAKISIDEIGLIIVATTTPDKTLPSCATIVQSKLKCKNAFSFDVQAACSGFIYAV
HHHHHHHHCCHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCEEEEE
TVADSLIKSHNRIKYALVIGAEIMSRIVDWEDRSTCVLFGDSAGAVIIKSEMGSSGIIST
HHHHHHHHCCCCEEEEEEECHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCEEEE
NLHSDGNVDILCTNGGVSSTRDSGKILMNGREVFKHAVDKLTASVEETLKCNNLKIIDID
CCCCCCCEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
WLIPHQANIRIIEAVVKKLDFPIEKVINTVDKHANTSAASIPLALDYAIQESKIKSGNLV
EECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEEHHHHCCCCCCCEE
LLISIGAGLTWGSVLLRY
EEEEECCCCCHHHHHHCC
>Mature Secondary Structure 
SKSFILSTGSYLPKKILSNNEIALIVETNDEWIRQRTGIVQRHIADEGELTSDLAVNAA
CCCEEEECCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
KNAIEKAKISIDEIGLIIVATTTPDKTLPSCATIVQSKLKCKNAFSFDVQAACSGFIYAV
HHHHHHHHCCHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCEEEEE
TVADSLIKSHNRIKYALVIGAEIMSRIVDWEDRSTCVLFGDSAGAVIIKSEMGSSGIIST
HHHHHHHHCCCCEEEEEEECHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCEEEE
NLHSDGNVDILCTNGGVSSTRDSGKILMNGREVFKHAVDKLTASVEETLKCNNLKIIDID
CCCCCCCEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
WLIPHQANIRIIEAVVKKLDFPIEKVINTVDKHANTSAASIPLALDYAIQESKIKSGNLV
EECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEEHHHHCCCCCCCEE
LLISIGAGLTWGSVLLRY
EEEEECCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA