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The map label for this gene is ctaA

Identifier: 190571026

GI number: 190571026

Start: 671429

End: 672424

Strand: Reverse

Name: ctaA

Synonym: WPa_0618

Alternate gene names: 190571026

Gene position: 672424-671429 (Counterclockwise)

Preceding gene: 190571027

Following gene: 190571023

Centisome position: 45.36

GC content: 34.14

Gene sequence:

>996_bases
ATGGAAGCAAAACCTGTAGCTATTTGGCTTTTTCTCTGCTCTCTCATGGTGATTTGCATGGTGGGAATTGGTGGATTTAC
CAGACTTTCAAAAGCAGGATTGTCAATCACGGAATGGAAACCAATTACCGGAACATTGCCACCGCTGAGTGAACAAGACT
GGCTAAAAGAAAAATCAAAATATGAAGCTACACCTGAATATAAAGCATTTAATTATGGTATGAGTATGGAAGAGTTTCGC
ACCATATACTTAATAGAATATGTGCACAGGTTAATTGCAAGGCTGACAGGTTTAGTTTTTATCTTACCATTTATATACTT
TACACTAAAAAAAAGAATACCTAAAAATGCAGTAATAAGGTTATCTACAGCACTATTATTTGGAATTTTACAAGCTTTTG
CCGGTTGGTATATGGTTAAAAGCGGTTTGGTATCTAATCCTCATGTTAGTCACTATAAGCTCGCACTTCACTTACTGCTT
GCGTTGGTTATCTTTGCATTATTGTCATATCAATTTTTTGATTACCAAATCAAACCAAAACAGATAATTAAAATTAATAG
CAACATTACATGTTACATATGGATAATTTTAATCCTAGTGACAGTACAAATAATCTTCGGTGCATTTGTTGCAGGGCTAA
ATGCTGGTTTAATTTATAATACCTTTCCACTAATGGATGGACAAATTGTTCCGGAAGATTTATTTTACTTACAGCCTGCT
TGGCTAAATATCTTTGAAAATAGAGTAACAGTGCAATTCATACACCGGGCATTGGCATTGCTGATATTAGTTCTGACAGC
AATACTCACAATAAAAAATGCCAGTATAAAACCATTATATGTTATGCTATTCTCCGTCATCATTCAGGTAATTCTAGGAA
TAGTCACTTTGTTGCTGCATATACCAATGGCTATTGCTATAGCCCATCAAATGTTTTCATTTATCTTATTTGGATCAGGT
TTATACTGCTTGCGTTATTTAAGAAATCAGATCTAA

Upstream 100 bases:

>100_bases
TTTTTCCCGTCTATAGTCTACTACATAGCGTTGCAGCTTTTCTCGCTTTGTGGGAATTTGTTATTCACCCTCAGCAATGG
AATAAAACTCAGCATGGATT

Downstream 100 bases:

>100_bases
TACCAAATCACCAGCATGTATATTTTTTCCTTCTTTAACAGGGATATTTTTTATCACCATTTCTGATTCAGCACATATTA
TATTTTCCATTTTCATTGCC

Product: cytochrome c oxidase assembly protein

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MEAKPVAIWLFLCSLMVICMVGIGGFTRLSKAGLSITEWKPITGTLPPLSEQDWLKEKSKYEATPEYKAFNYGMSMEEFR
TIYLIEYVHRLIARLTGLVFILPFIYFTLKKRIPKNAVIRLSTALLFGILQAFAGWYMVKSGLVSNPHVSHYKLALHLLL
ALVIFALLSYQFFDYQIKPKQIIKINSNITCYIWIILILVTVQIIFGAFVAGLNAGLIYNTFPLMDGQIVPEDLFYLQPA
WLNIFENRVTVQFIHRALALLILVLTAILTIKNASIKPLYVMLFSVIIQVILGIVTLLLHIPMAIAIAHQMFSFILFGSG
LYCLRYLRNQI

Sequences:

>Translated_331_residues
MEAKPVAIWLFLCSLMVICMVGIGGFTRLSKAGLSITEWKPITGTLPPLSEQDWLKEKSKYEATPEYKAFNYGMSMEEFR
TIYLIEYVHRLIARLTGLVFILPFIYFTLKKRIPKNAVIRLSTALLFGILQAFAGWYMVKSGLVSNPHVSHYKLALHLLL
ALVIFALLSYQFFDYQIKPKQIIKINSNITCYIWIILILVTVQIIFGAFVAGLNAGLIYNTFPLMDGQIVPEDLFYLQPA
WLNIFENRVTVQFIHRALALLILVLTAILTIKNASIKPLYVMLFSVIIQVILGIVTLLLHIPMAIAIAHQMFSFILFGSG
LYCLRYLRNQI
>Mature_331_residues
MEAKPVAIWLFLCSLMVICMVGIGGFTRLSKAGLSITEWKPITGTLPPLSEQDWLKEKSKYEATPEYKAFNYGMSMEEFR
TIYLIEYVHRLIARLTGLVFILPFIYFTLKKRIPKNAVIRLSTALLFGILQAFAGWYMVKSGLVSNPHVSHYKLALHLLL
ALVIFALLSYQFFDYQIKPKQIIKINSNITCYIWIILILVTVQIIFGAFVAGLNAGLIYNTFPLMDGQIVPEDLFYLQPA
WLNIFENRVTVQFIHRALALLILVLTAILTIKNASIKPLYVMLFSVIIQVILGIVTLLLHIPMAIAIAHQMFSFILFGSG
LYCLRYLRNQI

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=342, Percent_Identity=37.1345029239766, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI17921987, Length=274, Percent_Identity=40.1459854014599, Blast_Score=185, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI17536069, Length=344, Percent_Identity=35.4651162790698, Blast_Score=215, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6320989, Length=369, Percent_Identity=36.0433604336043, Blast_Score=197, Evalue=2e-51,
Organism=Drosophila melanogaster, GI19922860, Length=348, Percent_Identity=37.6436781609195, Blast_Score=204, Evalue=8e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_WOLPP (B3CLF8)

Other databases:

- EMBL:   AM999887
- RefSeq:   YP_001975384.1
- EnsemblBacteria:   EBWOLT00000000743
- GeneID:   6384586
- GenomeReviews:   AM999887_GR
- KEGG:   wpi:WPa_0618
- GeneTree:   EBGT00050000031023
- HOGENOM:   HBG628966
- OMA:   GLSIVEW
- ProtClustDB:   CLSK2761468
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 37735; Mature: 37735

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: BINDING 309-309

Signals:

None

Transmembrane regions:

HASH(0x17152ff0)-; HASH(0x16d992cc)-; HASH(0x17233f60)-; HASH(0x16b1afbc)-; HASH(0xe263b50)-; HASH(0x16f4ca94)-; HASH(0x171ec7e8)-; HASH(0x16fc381c)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAKPVAIWLFLCSLMVICMVGIGGFTRLSKAGLSITEWKPITGTLPPLSEQDWLKEKSK
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHHC
YEATPEYKAFNYGMSMEEFRTIYLIEYVHRLIARLTGLVFILPFIYFTLKKRIPKNAVIR
CCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LSTALLFGILQAFAGWYMVKSGLVSNPHVSHYKLALHLLLALVIFALLSYQFFDYQIKPK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCH
QIIKINSNITCYIWIILILVTVQIIFGAFVAGLNAGLIYNTFPLMDGQIVPEDLFYLQPA
HEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCCCCCCCHHHHHHCHH
WLNIFENRVTVQFIHRALALLILVLTAILTIKNASIKPLYVMLFSVIIQVILGIVTLLLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IPMAIAIAHQMFSFILFGSGLYCLRYLRNQI
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCH
>Mature Secondary Structure
MEAKPVAIWLFLCSLMVICMVGIGGFTRLSKAGLSITEWKPITGTLPPLSEQDWLKEKSK
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHHC
YEATPEYKAFNYGMSMEEFRTIYLIEYVHRLIARLTGLVFILPFIYFTLKKRIPKNAVIR
CCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LSTALLFGILQAFAGWYMVKSGLVSNPHVSHYKLALHLLLALVIFALLSYQFFDYQIKPK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCH
QIIKINSNITCYIWIILILVTVQIIFGAFVAGLNAGLIYNTFPLMDGQIVPEDLFYLQPA
HEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCCCCCCCHHHHHHCHH
WLNIFENRVTVQFIHRALALLILVLTAILTIKNASIKPLYVMLFSVIIQVILGIVTLLLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IPMAIAIAHQMFSFILFGSGLYCLRYLRNQI
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA