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The map label for this gene is fusA [H]

Identifier: 190570976

GI number: 190570976

Start: 607151

End: 609226

Strand: Reverse

Name: fusA [H]

Synonym: WPa_0562

Alternate gene names: 190570976

Gene position: 609226-607151 (Counterclockwise)

Preceding gene: 190570977

Following gene: 190570975

Centisome position: 41.1

GC content: 35.84

Gene sequence:

>2076_bases
ATGGAAGTTTTAATATCTAGGTATAGAAATATAGGAATAATGGCTCATATAGATGCTGGCAAGACCACCACAACAGAGCG
TATTTTATTTTATACTGGTAAACAAAATAGGATTGGTGAAGTGCACGATGGTGCAGCTTCTATGGATTGGATGGAGCAAG
AGAAGGAGCGTGGCATTACAATTACCTCTGCTGCAACAACATGTTTTTGGAATGATCATAGGATTAATATAATAGATACT
CCTGGTCATGTTGACTTCACTATTGAAGTTGAGAGATCTTTGAGGGTTTTGGATGGTGCGGTTGCTGTATTTGATGGAGT
TGCTGGAGTTGAGCCTCAGTCTGAGACAGTTTGGCGTCAAGCTGATAAATATAACGTTCCTCGTATCTGCTTTGTTAATA
AAATGGATAGAATCGGGGCAAATTTTTATCGATGTGTCGATATGATAAAAACGAAGCTTGGCGCATCACCTTTAGTTATT
CAGTTGCCAATAGGAAGTGAGAAAGATTTTAAAGGCATAATCGATCTTATTTCTATGAAAGCTATTATATGGCAAGAAGA
AACATTAGGCGCTAAATTTTCTTATGAAGATATTCCTTCTGATTTGCTTGATAAAGCTCAAGAGTATCGAAATCTTTTAT
TAGATGCTGCAGCTGAAATGGATGATGAGGCGATAAATACTTACTTTGAATCTAACGATCTGCCAATTGATTTGTTGAAA
AAGTGTGTGAGAAGCGGGACCATTAAAGGAAAATTTGTCCCTGTATTATGTGGGTCAGCTTTTAAAAACAAAGGCGTGCA
ATCACTTTTAGATGGTGTGGTTGATTTTTTACCCTCTCCTATTGATGTTGATGTAATTATTGGAACTGATCCTAAAGATT
CAGAAAAGAAAATTGAGATCAAACCTTCAGAAAAAGAGAAATTCGTTGCTCTTGCGTTTAAAGTGATGACGGATAAATTT
GTAGGTAGCTTGACGTTTATTCGTATTTATTCCGGTAAGTTAAAATCTAAATCTGCTGTGTTAAATGCTGGAAAGAATGA
GACTGAAGGAATTGGTAGAATGTTGCTTATGCATGCAAATAACAGAGAAGATATAAACGAAGCTAAAGTTGGTGATATAG
TTGCCTTAGTTGGATTAAAGAAAACAATTACTGGTGATACTTTATGTTCATCTGATTTTCCTATACTATTAGAGCGTATG
GAATTTCCTGATCCTGTTATTGAAATTGCTATAGAACCGAAAACCACCTCAGATCAGGAAAAATTAGGTGTTGCTTTGAA
TAGATTGGTTGCAGAAGATCCTTCTTTAAGGATGTCAGTAAATGCAGAGAGTGGGCAGACTATATTGAAAGGTATGGGTG
AGCTGCATCTTGAGATTATTATTGATAGAATGAAGCGCGAGTTTAATGTTGAAGCTAACGTTGGTGCGCCTCAAGTTGCA
TATCGTGAAACTATCACTAAATCTGTTGAAATTGATTACACTCATAAAAAACAATCAGGTGGTGCTGGTCAGTTTGCTAA
AGTTAAAATAAAATTCGAACCTCTTGAGCCTGGTTTTGGCTTTCAGTTTGAAAGTAAAATTGTAGGCGGTGCTATTCCAA
AAGAGTATATACCTGGAGTGCAAAATGGCTTAGAGTTGATAAAAGAAGGTGGTATAATTTCCGGCTTTCCATTGATTGAT
TTTAAGGCTACTCTTCTTGATGGTGCTTTTCATGATGTTGATTCTAGTCCTTTGGCTTTTGAACTTGCTGCTAAAGGTGC
TTTTAAGGAAATGGCAAATAAAGCTGGTCCAAAAATGCTAGAACCTATAATGAAAGTGGAAATCATTACTCCTGAAGAAT
ATATGGGTGATGTTATGGGTGATATAAATAGTAGAAGAGGCAGTGTTGTTGATATGCTGGATTTAGGTAATAATAGCAAA
ATAATTACTGCTTCGGTTCCTCTTGCAAATATGTTTGGTTATATAAATGTTTTGCGTTCTATATCTCAGGGAAGAGCTCA
GTATAGTATGCATTTTTCTTGTTATGAACAAGTGCCACAATATGTGGTTGATGAGTTAAAGTTAAAGTATAATTAA

Upstream 100 bases:

>100_bases
TGGTGGTGCATTTAAGATGTGTGAAGAAAAGTATAAAATGGCTGAAGCTAATAAGGCATTTTCTCATCTTCGTTTTTAAT
ATTAGCTGATTGATTGTGGT

Downstream 100 bases:

>100_bases
AGGTTAGTAATTATGACAGCGATAGTAGAAGCATTTGGAAAGCCGCATGTAAATGTGGGAACGATAGGACATGTGGATCA
TGGGAAGACAACGTTAACAG

Product: elongation factor G

Products: NA

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 691; Mature: 691

Protein sequence:

>691_residues
MEVLISRYRNIGIMAHIDAGKTTTTERILFYTGKQNRIGEVHDGAASMDWMEQEKERGITITSAATTCFWNDHRINIIDT
PGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVPRICFVNKMDRIGANFYRCVDMIKTKLGASPLVI
QLPIGSEKDFKGIIDLISMKAIIWQEETLGAKFSYEDIPSDLLDKAQEYRNLLLDAAAEMDDEAINTYFESNDLPIDLLK
KCVRSGTIKGKFVPVLCGSAFKNKGVQSLLDGVVDFLPSPIDVDVIIGTDPKDSEKKIEIKPSEKEKFVALAFKVMTDKF
VGSLTFIRIYSGKLKSKSAVLNAGKNETEGIGRMLLMHANNREDINEAKVGDIVALVGLKKTITGDTLCSSDFPILLERM
EFPDPVIEIAIEPKTTSDQEKLGVALNRLVAEDPSLRMSVNAESGQTILKGMGELHLEIIIDRMKREFNVEANVGAPQVA
YRETITKSVEIDYTHKKQSGGAGQFAKVKIKFEPLEPGFGFQFESKIVGGAIPKEYIPGVQNGLELIKEGGIISGFPLID
FKATLLDGAFHDVDSSPLAFELAAKGAFKEMANKAGPKMLEPIMKVEIITPEEYMGDVMGDINSRRGSVVDMLDLGNNSK
IITASVPLANMFGYINVLRSISQGRAQYSMHFSCYEQVPQYVVDELKLKYN

Sequences:

>Translated_691_residues
MEVLISRYRNIGIMAHIDAGKTTTTERILFYTGKQNRIGEVHDGAASMDWMEQEKERGITITSAATTCFWNDHRINIIDT
PGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVPRICFVNKMDRIGANFYRCVDMIKTKLGASPLVI
QLPIGSEKDFKGIIDLISMKAIIWQEETLGAKFSYEDIPSDLLDKAQEYRNLLLDAAAEMDDEAINTYFESNDLPIDLLK
KCVRSGTIKGKFVPVLCGSAFKNKGVQSLLDGVVDFLPSPIDVDVIIGTDPKDSEKKIEIKPSEKEKFVALAFKVMTDKF
VGSLTFIRIYSGKLKSKSAVLNAGKNETEGIGRMLLMHANNREDINEAKVGDIVALVGLKKTITGDTLCSSDFPILLERM
EFPDPVIEIAIEPKTTSDQEKLGVALNRLVAEDPSLRMSVNAESGQTILKGMGELHLEIIIDRMKREFNVEANVGAPQVA
YRETITKSVEIDYTHKKQSGGAGQFAKVKIKFEPLEPGFGFQFESKIVGGAIPKEYIPGVQNGLELIKEGGIISGFPLID
FKATLLDGAFHDVDSSPLAFELAAKGAFKEMANKAGPKMLEPIMKVEIITPEEYMGDVMGDINSRRGSVVDMLDLGNNSK
IITASVPLANMFGYINVLRSISQGRAQYSMHFSCYEQVPQYVVDELKLKYN
>Mature_691_residues
MEVLISRYRNIGIMAHIDAGKTTTTERILFYTGKQNRIGEVHDGAASMDWMEQEKERGITITSAATTCFWNDHRINIIDT
PGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVPRICFVNKMDRIGANFYRCVDMIKTKLGASPLVI
QLPIGSEKDFKGIIDLISMKAIIWQEETLGAKFSYEDIPSDLLDKAQEYRNLLLDAAAEMDDEAINTYFESNDLPIDLLK
KCVRSGTIKGKFVPVLCGSAFKNKGVQSLLDGVVDFLPSPIDVDVIIGTDPKDSEKKIEIKPSEKEKFVALAFKVMTDKF
VGSLTFIRIYSGKLKSKSAVLNAGKNETEGIGRMLLMHANNREDINEAKVGDIVALVGLKKTITGDTLCSSDFPILLERM
EFPDPVIEIAIEPKTTSDQEKLGVALNRLVAEDPSLRMSVNAESGQTILKGMGELHLEIIIDRMKREFNVEANVGAPQVA
YRETITKSVEIDYTHKKQSGGAGQFAKVKIKFEPLEPGFGFQFESKIVGGAIPKEYIPGVQNGLELIKEGGIISGFPLID
FKATLLDGAFHDVDSSPLAFELAAKGAFKEMANKAGPKMLEPIMKVEIITPEEYMGDVMGDINSRRGSVVDMLDLGNNSK
IITASVPLANMFGYINVLRSISQGRAQYSMHFSCYEQVPQYVVDELKLKYN

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=681, Percent_Identity=43.3186490455213, Blast_Score=535, Evalue=1e-152,
Organism=Homo sapiens, GI19923640, Length=717, Percent_Identity=41.9804741980474, Blast_Score=508, Evalue=1e-144,
Organism=Homo sapiens, GI25306283, Length=450, Percent_Identity=46.6666666666667, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI25306287, Length=287, Percent_Identity=54.006968641115, Blast_Score=298, Evalue=1e-80,
Organism=Homo sapiens, GI4503483, Length=478, Percent_Identity=24.4769874476987, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI94966754, Length=136, Percent_Identity=38.9705882352941, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI157426893, Length=150, Percent_Identity=34, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI310132016, Length=117, Percent_Identity=37.6068376068376, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI310110807, Length=117, Percent_Identity=37.6068376068376, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI310123363, Length=117, Percent_Identity=37.6068376068376, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI94966752, Length=67, Percent_Identity=46.2686567164179, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1789738, Length=693, Percent_Identity=57.7200577200577, Blast_Score=800, Evalue=0.0,
Organism=Escherichia coli, GI1790835, Length=498, Percent_Identity=27.5100401606426, Blast_Score=170, Evalue=3e-43,
Organism=Escherichia coli, GI48994988, Length=176, Percent_Identity=39.2045454545455, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1788922, Length=151, Percent_Identity=36.4238410596026, Blast_Score=90, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17533571, Length=682, Percent_Identity=40.4692082111437, Blast_Score=494, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17556745, Length=716, Percent_Identity=28.2122905027933, Blast_Score=312, Evalue=3e-85,
Organism=Caenorhabditis elegans, GI17506493, Length=481, Percent_Identity=24.7401247401247, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17557151, Length=136, Percent_Identity=38.2352941176471, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71988819, Length=132, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71988811, Length=132, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17552882, Length=135, Percent_Identity=34.0740740740741, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323098, Length=689, Percent_Identity=40.6386066763425, Blast_Score=537, Evalue=1e-153,
Organism=Saccharomyces cerevisiae, GI6322359, Length=787, Percent_Identity=32.5285895806862, Blast_Score=385, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6324707, Length=608, Percent_Identity=27.3026315789474, Blast_Score=160, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6320593, Length=608, Percent_Identity=27.3026315789474, Blast_Score=160, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6323320, Length=145, Percent_Identity=35.1724137931034, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324166, Length=146, Percent_Identity=35.6164383561644, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582462, Length=699, Percent_Identity=43.3476394849785, Blast_Score=555, Evalue=1e-158,
Organism=Drosophila melanogaster, GI221458488, Length=713, Percent_Identity=35.203366058906, Blast_Score=423, Evalue=1e-118,
Organism=Drosophila melanogaster, GI78706572, Length=158, Percent_Identity=36.7088607594937, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24585711, Length=151, Percent_Identity=39.7350993377483, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24585713, Length=151, Percent_Identity=39.7350993377483, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24585709, Length=151, Percent_Identity=39.7350993377483, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28574573, Length=151, Percent_Identity=36.4238410596026, Blast_Score=86, Evalue=9e-17,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 76475; Mature: 76475

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVLISRYRNIGIMAHIDAGKTTTTERILFYTGKQNRIGEVHDGAASMDWMEQEKERGIT
CCCHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCEE
ITSAATTCFWNDHRINIIDTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQ
EEECEEEEEECCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ADKYNVPRICFVNKMDRIGANFYRCVDMIKTKLGASPLVIQLPIGSEKDFKGIIDLISMK
HCCCCCCEEEEECCHHHHCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHH
AIIWQEETLGAKFSYEDIPSDLLDKAQEYRNLLLDAAAEMDDEAINTYFESNDLPIDLLK
HHEEEHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHH
KCVRSGTIKGKFVPVLCGSAFKNKGVQSLLDGVVDFLPSPIDVDVIIGTDPKDSEKKIEI
HHHHCCCCCCEEEEEECCCHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEE
KPSEKEKFVALAFKVMTDKFVGSLTFIRIYSGKLKSKSAVLNAGKNETEGIGRMLLMHAN
CCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHCCCCCCCCCCCEEEEEECC
NREDINEAKVGDIVALVGLKKTITGDTLCSSDFPILLERMEFPDPVIEIAIEPKTTSDQE
CCCCCCHHHHHHEEEEECCHHHCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCHH
KLGVALNRLVAEDPSLRMSVNAESGQTILKGMGELHLEIIIDRMKREFNVEANVGAPQVA
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHH
YRETITKSVEIDYTHKKQSGGAGQFAKVKIKFEPLEPGFGFQFESKIVGGAIPKEYIPGV
HHHHHHCCEEEEEEECCCCCCCCCEEEEEEEEEECCCCCCCEECCCCCCCCCCHHHCCCH
QNGLELIKEGGIISGFPLIDFKATLLDGAFHDVDSSPLAFELAAKGAFKEMANKAGPKML
HHHHHHHHCCCEEECCCCCCCHHHHHCCHHHCCCCCCEEEEEHHHHHHHHHHHHCCHHHH
EPIMKVEIITPEEYMGDVMGDINSRRGSVVDMLDLGNNSKIITASVPLANMFGYINVLRS
HHHHEEEEECCHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHH
ISQGRAQYSMHFSCYEQVPQYVVDELKLKYN
HHCCCHHEEEEHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEVLISRYRNIGIMAHIDAGKTTTTERILFYTGKQNRIGEVHDGAASMDWMEQEKERGIT
CCCHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCEE
ITSAATTCFWNDHRINIIDTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQ
EEECEEEEEECCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ADKYNVPRICFVNKMDRIGANFYRCVDMIKTKLGASPLVIQLPIGSEKDFKGIIDLISMK
HCCCCCCEEEEECCHHHHCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHH
AIIWQEETLGAKFSYEDIPSDLLDKAQEYRNLLLDAAAEMDDEAINTYFESNDLPIDLLK
HHEEEHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHH
KCVRSGTIKGKFVPVLCGSAFKNKGVQSLLDGVVDFLPSPIDVDVIIGTDPKDSEKKIEI
HHHHCCCCCCEEEEEECCCHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEE
KPSEKEKFVALAFKVMTDKFVGSLTFIRIYSGKLKSKSAVLNAGKNETEGIGRMLLMHAN
CCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHCCCCCCCCCCCEEEEEECC
NREDINEAKVGDIVALVGLKKTITGDTLCSSDFPILLERMEFPDPVIEIAIEPKTTSDQE
CCCCCCHHHHHHEEEEECCHHHCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCHH
KLGVALNRLVAEDPSLRMSVNAESGQTILKGMGELHLEIIIDRMKREFNVEANVGAPQVA
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHH
YRETITKSVEIDYTHKKQSGGAGQFAKVKIKFEPLEPGFGFQFESKIVGGAIPKEYIPGV
HHHHHHCCEEEEEEECCCCCCCCCEEEEEEEEEECCCCCCCEECCCCCCCCCCHHHCCCH
QNGLELIKEGGIISGFPLIDFKATLLDGAFHDVDSSPLAFELAAKGAFKEMANKAGPKML
HHHHHHHHCCCEEECCCCCCCHHHHHCCHHHCCCCCCEEEEEHHHHHHHHHHHHCCHHHH
EPIMKVEIITPEEYMGDVMGDINSRRGSVVDMLDLGNNSKIITASVPLANMFGYINVLRS
HHHHEEEEECCHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHH
ISQGRAQYSMHFSCYEQVPQYVVDELKLKYN
HHCCCHHEEEEHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA