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The map label for this gene is cutA [H]

Identifier: 190570957

GI number: 190570957

Start: 578951

End: 579286

Strand: Reverse

Name: cutA [H]

Synonym: WPa_0540

Alternate gene names: 190570957

Gene position: 579286-578951 (Counterclockwise)

Preceding gene: 190570960

Following gene: 190570956

Centisome position: 39.08

GC content: 30.65

Gene sequence:

>336_bases
ATGAGCAACTTAGTTTTAGTCTATATAACTTTTTCAAACCTGAAAGAGGCTAAGACTATTTCTGAAGAATTGTTAAACGA
GAAGTTAATTGCATGTGTAAATATATTTCCCAAAGTAAATTCTCTGTATTTATGGGAAGGTAAAATTAATAGTAATTGTG
AAATAGTGGCAATTATGAAGAGCAGGAATGATCAGACTGATAAGATTGTAGAAAAAATCGAGGCAATGCATTCTTATGAT
CAACCAGCCGTTGTGATAATACCCATAGGAAAAGCGAATAAATCTTTTACTAATTGGGTTAATAATGTTATTGATATAAA
CAATATTGGGGTGTAG

Upstream 100 bases:

>100_bases
TTCAATTTCTATGTGTCAAGCACTGAAGAGGTCTCTCCTATTTTCTCTTGATGAATAAATCTAAGTAGAGTATAGTAAAA
ATGCATTTATGTAGCGATTA

Downstream 100 bases:

>100_bases
CCAAGTGGTAAGGCAGCGGTTTTTGATACCGCCACGCGAAGGTTCGAATCCTTCCACCCCAGCTTTATTAAAGTGTGCGT
GAAATGATATCACTTTTTTA

Product: periplasmic divalent cation tolerance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 111; Mature: 110

Protein sequence:

>111_residues
MSNLVLVYITFSNLKEAKTISEELLNEKLIACVNIFPKVNSLYLWEGKINSNCEIVAIMKSRNDQTDKIVEKIEAMHSYD
QPAVVIIPIGKANKSFTNWVNNVIDINNIGV

Sequences:

>Translated_111_residues
MSNLVLVYITFSNLKEAKTISEELLNEKLIACVNIFPKVNSLYLWEGKINSNCEIVAIMKSRNDQTDKIVEKIEAMHSYD
QPAVVIIPIGKANKSFTNWVNNVIDINNIGV
>Mature_110_residues
SNLVLVYITFSNLKEAKTISEELLNEKLIACVNIFPKVNSLYLWEGKINSNCEIVAIMKSRNDQTDKIVEKIEAMHSYDQ
PAVVIIPIGKANKSFTNWVNNVIDINNIGV

Specific function: Involved in resistance toward heavy metals [H]

COG id: COG1324

COG function: function code P; Uncharacterized protein involved in tolerance to divalent cations

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutA family [H]

Homologues:

Organism=Homo sapiens, GI62526026, Length=98, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=7e-14,
Organism=Homo sapiens, GI62198241, Length=98, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=8e-14,
Organism=Homo sapiens, GI62526024, Length=98, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=9e-14,
Organism=Homo sapiens, GI62526022, Length=98, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=9e-14,
Organism=Homo sapiens, GI7706244, Length=98, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790579, Length=97, Percent_Identity=28.8659793814433, Blast_Score=70, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32565476, Length=98, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24641937, Length=99, Percent_Identity=28.2828282828283, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004323
- InterPro:   IPR011322 [H]

Pfam domain/function: PF03091 CutA1 [H]

EC number: NA

Molecular weight: Translated: 12527; Mature: 12396

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLVLVYITFSNLKEAKTISEELLNEKLIACVNIFPKVNSLYLWEGKINSNCEIVAIMK
CCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEC
SRNDQTDKIVEKIEAMHSYDQPAVVIIPIGKANKSFTNWVNNVIDINNIGV
CCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SNLVLVYITFSNLKEAKTISEELLNEKLIACVNIFPKVNSLYLWEGKINSNCEIVAIMK
CCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEC
SRNDQTDKIVEKIEAMHSYDQPAVVIIPIGKANKSFTNWVNNVIDINNIGV
CCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]