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The map label for this gene is ppiD [H]

Identifier: 190570945

GI number: 190570945

Start: 564439

End: 566238

Strand: Reverse

Name: ppiD [H]

Synonym: WPa_0526

Alternate gene names: 190570945

Gene position: 566238-564439 (Counterclockwise)

Preceding gene: 190570948

Following gene: 190570944

Centisome position: 38.2

GC content: 30.94

Gene sequence:

>1800_bases
ATGAGTATTAGAAATTTTTTTACCAAGGCAATCGTTCTCCTTTTAGTTTGCTTATTAATCTTTATGGGGATTGGCAATCT
TTTATCAAATGATGATGAAAGGAAAGAATTAGCTAAAGTAGGAAAGGAAGTTATAACATCAGATGAATATAAATTACTAT
ATCAAAATTATAAAAAGCAAATTTCTGGATCTGATGTAAGTAAAGAACAAGTAAAAAAGCTGAAATATGATTTACTTAAC
GCACTTATAGAGCAAAAACTATTGTTTAACCTAATTAGCGAACTTGGATTAAAAGTTGGAGAAGAATCTATCAAAAGCCA
CATAAAAAATACCAAGTACTTTCAGGACGATAAAGGAGAATTTGACCATAATAAATTCCATCAAACTCTAAATAGCCTGC
ATATAACAGAAAAGGAATATATAGAAAAACTAGAGAAAATCCTGCCTGCAATGATGTTCATGACTTCGTTATTTAAAGAT
AATTATCCGGTAACTTTTGGTGAGGGTGTTGATGAGCAGATATACAAAAATCGCTACCAAACTAGAGTAGTTGATATTGT
TAAAATAACTGAGGATGCAATTACAGACGTTCCTGAACCAGATGATCAAGCCTTACTTGATTTGTATGAAAGAAATAAGT
CCAATTTTTATTACCCTGAGTATCGAACTGCGCAATACATTTCTCTGGATCAAAAATATTTTGAAGATCAAATCAGAATT
TCAGATGAAGAGGTTGATAGTATAATAGAACATCAGGAACTTAAAAATCAAAGAGACATATTCAATGTGATATTTCCTAC
CAAAGAAAAAGCTGAAATAGCAAGAAGAGCACTTGAAGAAAGTAAAGCAAGCTTTGAACAAATAATAGAAGAGTTTAATA
AAGTGAAACTCGATGAAACCAGAGTAAATAATATAACTAAGGATTTCTTACCTGAAAATATGAGAGAAAAGGTATTTGCT
CTCAAAACAGGTGAAGTAAGTGAAGTTTTAACAAGCAATTTTGGATGGCACGTAATAAAGGTAGAAAGCATACATCAAAT
CTCTGATGAAGACTTGGTTGATTTAAAAAAAGACATAAGGTCAGTTTTAACCAATCAAAAGTCTTTTGAAAAAGTCAATG
ATTTCATAAATCAAGTGAATTATAAGATATACAATGGTGCAACGATTGAAGAAATCTCCAATAATTACAATTTACCTATA
CAAACCATTGGTCCAGTAGATGCTAGTGGAAAAGACCAAAGTGGTAATGAAGTAGGAAATTCCAGTGATTTCATTTCTTT
CATTTTTTCACGCGAGAAAGATCAGAAGAGTTATTTTAAGGGTGTTGGAGATACTGTTGTTGGTGTAAAAATCAGTGATA
TCGTTCCTCCTAAATTACAAAATTTTGAAGAAAGTAGGGAATCAGCCATAAAGCTTTGGCGTAGTGAATTTATAAAAGAA
AGAATGTTTAAAATGGGACAAGAAGTAGCAGTTCAACTAAGAGAAAAGACAGATTTGGAAGAAATGCAAGGTATAAAATT
GGTTAAAGGCCAGCAAATACAACGCAATGAACAAAACTACCCTTTTTCTTTCATAGAAGAGATTTTCAATATGAAAACAA
CTAATTCGGTAACAGATCCTATTCAATACAATAATGAAATTATAATAGGCGTTCTAAAACAAATGCATTCATCAAATGGT
AAATTAAACATGCTTGACACCGGAAAACGTGTGATGATATCGCTAAAGGAACAGTTAATTAGCTATCTAAAATCAAAGTA
TAGAGTAGAAGTTAATCATGCTATGATTGATGATATATAA

Upstream 100 bases:

>100_bases
ATACACTACAATATTACATATATTAGCTAATTTATTAATAGATTTACAAATATTAAATTATTGCTATTCTAAATTTAAGT
GTTAGTTAACTAAGTTTACA

Downstream 100 bases:

>100_bases
AAAAGTTTATTATCTTCCTTTTATGAGTGATTAGAGGGGGCTATATTGTATTTTTAGGTAAAAGAGGTACAATTAGTTTG
ACTTGAGCTGTTTATTGTAT

Product: peptidyl-prolyl cis-trans isomerse D, putative

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 599; Mature: 598

Protein sequence:

>599_residues
MSIRNFFTKAIVLLLVCLLIFMGIGNLLSNDDERKELAKVGKEVITSDEYKLLYQNYKKQISGSDVSKEQVKKLKYDLLN
ALIEQKLLFNLISELGLKVGEESIKSHIKNTKYFQDDKGEFDHNKFHQTLNSLHITEKEYIEKLEKILPAMMFMTSLFKD
NYPVTFGEGVDEQIYKNRYQTRVVDIVKITEDAITDVPEPDDQALLDLYERNKSNFYYPEYRTAQYISLDQKYFEDQIRI
SDEEVDSIIEHQELKNQRDIFNVIFPTKEKAEIARRALEESKASFEQIIEEFNKVKLDETRVNNITKDFLPENMREKVFA
LKTGEVSEVLTSNFGWHVIKVESIHQISDEDLVDLKKDIRSVLTNQKSFEKVNDFINQVNYKIYNGATIEEISNNYNLPI
QTIGPVDASGKDQSGNEVGNSSDFISFIFSREKDQKSYFKGVGDTVVGVKISDIVPPKLQNFEESRESAIKLWRSEFIKE
RMFKMGQEVAVQLREKTDLEEMQGIKLVKGQQIQRNEQNYPFSFIEEIFNMKTTNSVTDPIQYNNEIIIGVLKQMHSSNG
KLNMLDTGKRVMISLKEQLISYLKSKYRVEVNHAMIDDI

Sequences:

>Translated_599_residues
MSIRNFFTKAIVLLLVCLLIFMGIGNLLSNDDERKELAKVGKEVITSDEYKLLYQNYKKQISGSDVSKEQVKKLKYDLLN
ALIEQKLLFNLISELGLKVGEESIKSHIKNTKYFQDDKGEFDHNKFHQTLNSLHITEKEYIEKLEKILPAMMFMTSLFKD
NYPVTFGEGVDEQIYKNRYQTRVVDIVKITEDAITDVPEPDDQALLDLYERNKSNFYYPEYRTAQYISLDQKYFEDQIRI
SDEEVDSIIEHQELKNQRDIFNVIFPTKEKAEIARRALEESKASFEQIIEEFNKVKLDETRVNNITKDFLPENMREKVFA
LKTGEVSEVLTSNFGWHVIKVESIHQISDEDLVDLKKDIRSVLTNQKSFEKVNDFINQVNYKIYNGATIEEISNNYNLPI
QTIGPVDASGKDQSGNEVGNSSDFISFIFSREKDQKSYFKGVGDTVVGVKISDIVPPKLQNFEESRESAIKLWRSEFIKE
RMFKMGQEVAVQLREKTDLEEMQGIKLVKGQQIQRNEQNYPFSFIEEIFNMKTTNSVTDPIQYNNEIIIGVLKQMHSSNG
KLNMLDTGKRVMISLKEQLISYLKSKYRVEVNHAMIDDI
>Mature_598_residues
SIRNFFTKAIVLLLVCLLIFMGIGNLLSNDDERKELAKVGKEVITSDEYKLLYQNYKKQISGSDVSKEQVKKLKYDLLNA
LIEQKLLFNLISELGLKVGEESIKSHIKNTKYFQDDKGEFDHNKFHQTLNSLHITEKEYIEKLEKILPAMMFMTSLFKDN
YPVTFGEGVDEQIYKNRYQTRVVDIVKITEDAITDVPEPDDQALLDLYERNKSNFYYPEYRTAQYISLDQKYFEDQIRIS
DEEVDSIIEHQELKNQRDIFNVIFPTKEKAEIARRALEESKASFEQIIEEFNKVKLDETRVNNITKDFLPENMREKVFAL
KTGEVSEVLTSNFGWHVIKVESIHQISDEDLVDLKKDIRSVLTNQKSFEKVNDFINQVNYKIYNGATIEEISNNYNLPIQ
TIGPVDASGKDQSGNEVGNSSDFISFIFSREKDQKSYFKGVGDTVVGVKISDIVPPKLQNFEESRESAIKLWRSEFIKER
MFKMGQEVAVQLREKTDLEEMQGIKLVKGQQIQRNEQNYPFSFIEEIFNMKTTNSVTDPIQYNNEIIIGVLKQMHSSNGK
LNMLDTGKRVMISLKEQLISYLKSKYRVEVNHAMIDDI

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=313, Percent_Identity=25.2396166134185, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69650; Mature: 69519

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRNFFTKAIVLLLVCLLIFMGIGNLLSNDDERKELAKVGKEVITSDEYKLLYQNYKKQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ISGSDVSKEQVKKLKYDLLNALIEQKLLFNLISELGLKVGEESIKSHIKNTKYFQDDKGE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCC
FDHNKFHQTLNSLHITEKEYIEKLEKILPAMMFMTSLFKDNYPVTFGEGVDEQIYKNRYQ
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHH
TRVVDIVKITEDAITDVPEPDDQALLDLYERNKSNFYYPEYRTAQYISLDQKYFEDQIRI
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
SDEEVDSIIEHQELKNQRDIFNVIFPTKEKAEIARRALEESKASFEQIIEEFNKVKLDET
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
RVNNITKDFLPENMREKVFALKTGEVSEVLTSNFGWHVIKVESIHQISDEDLVDLKKDIR
HHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEHHHHHCCCHHHHHHHHHHH
SVLTNQKSFEKVNDFINQVNYKIYNGATIEEISNNYNLPIQTIGPVDASGKDQSGNEVGN
HHHCCHHHHHHHHHHHHHCCEEEECCCHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCC
SSDFISFIFSREKDQKSYFKGVGDTVVGVKISDIVPPKLQNFEESRESAIKLWRSEFIKE
CHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RMFKMGQEVAVQLREKTDLEEMQGIKLVKGQQIQRNEQNYPFSFIEEIFNMKTTNSVTDP
HHHHHHHHHHHHHHHHCCHHHHCCCCHHCCCHHHCCCCCCCHHHHHHHHCCCCCCCCCCC
IQYNNEIIIGVLKQMHSSNGKLNMLDTGKRVMISLKEQLISYLKSKYRVEVNHAMIDDI
HHCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHEEEEHHHHHCCC
>Mature Secondary Structure 
SIRNFFTKAIVLLLVCLLIFMGIGNLLSNDDERKELAKVGKEVITSDEYKLLYQNYKKQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ISGSDVSKEQVKKLKYDLLNALIEQKLLFNLISELGLKVGEESIKSHIKNTKYFQDDKGE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCC
FDHNKFHQTLNSLHITEKEYIEKLEKILPAMMFMTSLFKDNYPVTFGEGVDEQIYKNRYQ
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHH
TRVVDIVKITEDAITDVPEPDDQALLDLYERNKSNFYYPEYRTAQYISLDQKYFEDQIRI
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
SDEEVDSIIEHQELKNQRDIFNVIFPTKEKAEIARRALEESKASFEQIIEEFNKVKLDET
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
RVNNITKDFLPENMREKVFALKTGEVSEVLTSNFGWHVIKVESIHQISDEDLVDLKKDIR
HHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEHHHHHCCCHHHHHHHHHHH
SVLTNQKSFEKVNDFINQVNYKIYNGATIEEISNNYNLPIQTIGPVDASGKDQSGNEVGN
HHHCCHHHHHHHHHHHHHCCEEEECCCHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCC
SSDFISFIFSREKDQKSYFKGVGDTVVGVKISDIVPPKLQNFEESRESAIKLWRSEFIKE
CHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RMFKMGQEVAVQLREKTDLEEMQGIKLVKGQQIQRNEQNYPFSFIEEIFNMKTTNSVTDP
HHHHHHHHHHHHHHHHCCHHHHCCCCHHCCCHHHCCCCCCCHHHHHHHHCCCCCCCCCCC
IQYNNEIIIGVLKQMHSSNGKLNMLDTGKRVMISLKEQLISYLKSKYRVEVNHAMIDDI
HHCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHEEEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]