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The map label for this gene is ccmC [H]

Identifier: 190570907

GI number: 190570907

Start: 522890

End: 523600

Strand: Direct

Name: ccmC [H]

Synonym: WPa_0487

Alternate gene names: 190570907

Gene position: 522890-523600 (Clockwise)

Preceding gene: 190570904

Following gene: 190570908

Centisome position: 35.27

GC content: 37.27

Gene sequence:

>711_bases
ATGTTTTTATTAAAGCCTACAAATTTCACTTCTTTTACTAAAAAAGCTCTACCTTGGCTTGGGGTTATTTGTTTCGCATG
TTTTTTAATTGGAATGTTCTTAGCATTATTCTTCTCCCCAGGAGATTATAAACAAGGAGAAATCGTACGAATTATGTATC
TTCATGTGCCTTCTGCATGGCTTGCTCTTGGAATATACGGACTCATTGCATCACTCAGTTTCATTTCATTGGTGTGGAAC
AATAGCGTTGCTAGTGTTTTGGCACATGCTGCTGCTCCTGCAGGGACAGTCTTTTCGGCAATATGCTTAATCACAGGTAG
CGTCTGGGGAAAAGGAACATGGGGTACTTGGTGGGTATGGGATGCAAGGCTTACTTCAATGCTGATTTTGTTTTTTCTGT
ATGTTGGTTATCTTTCATTGTGGAGCGCTTTTGATAATCAAGCAAGAGCAGAGAAATCATCAGCAGTATTTGCCATTTTT
AGTGCTATAAATATTCCCATAGTAAAATTTTCTGTGAATTTATGGTCTACTCTTCATCAGCCAGCAAGTATTTTTAGAAA
AGGTGGAGTAGCAATAGAAGGTTCTTTACTGCTGCCACTCATTGCAATGTTTATATTTTGTACCACACTTTTTTTAGTAG
TGTGGATACTTAATGCCCTTCATTTAATTAATTTGCAGAAGATAAAGAGAGAAATCAGTATGCGGTATTAG

Upstream 100 bases:

>100_bases
ATTGTGCTAATTTATTATACTACGTAAATATAGAAAAACTATCTTGTTGATAAAACTCAAACTAATTGATAAATTCTTAA
CACAATTATTCTCAAAACAA

Downstream 100 bases:

>100_bases
GTATGCAGTTCCAGAGTGTAATGTTGTGAACAGCGACAGAGATTAAAATGTAGAGCAATCATCCATTAGCAAGTTCCAGA
ACTAATTACGTACAAACCAC

Product: heme exporter protein CcmC

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycZ [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MFLLKPTNFTSFTKKALPWLGVICFACFLIGMFLALFFSPGDYKQGEIVRIMYLHVPSAWLALGIYGLIASLSFISLVWN
NSVASVLAHAAAPAGTVFSAICLITGSVWGKGTWGTWWVWDARLTSMLILFFLYVGYLSLWSAFDNQARAEKSSAVFAIF
SAINIPIVKFSVNLWSTLHQPASIFRKGGVAIEGSLLLPLIAMFIFCTTLFLVVWILNALHLINLQKIKREISMRY

Sequences:

>Translated_236_residues
MFLLKPTNFTSFTKKALPWLGVICFACFLIGMFLALFFSPGDYKQGEIVRIMYLHVPSAWLALGIYGLIASLSFISLVWN
NSVASVLAHAAAPAGTVFSAICLITGSVWGKGTWGTWWVWDARLTSMLILFFLYVGYLSLWSAFDNQARAEKSSAVFAIF
SAINIPIVKFSVNLWSTLHQPASIFRKGGVAIEGSLLLPLIAMFIFCTTLFLVVWILNALHLINLQKIKREISMRY
>Mature_236_residues
MFLLKPTNFTSFTKKALPWLGVICFACFLIGMFLALFFSPGDYKQGEIVRIMYLHVPSAWLALGIYGLIASLSFISLVWN
NSVASVLAHAAAPAGTVFSAICLITGSVWGKGTWGTWWVWDARLTSMLILFFLYVGYLSLWSAFDNQARAEKSSAVFAIF
SAINIPIVKFSVNLWSTLHQPASIFRKGGVAIEGSLLLPLIAMFIFCTTLFLVVWILNALHLINLQKIKREISMRY

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=184, Percent_Identity=44.0217391304348, Blast_Score=171, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 26333; Mature: 26333

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLLKPTNFTSFTKKALPWLGVICFACFLIGMFLALFFSPGDYKQGEIVRIMYLHVPSAW
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCHHH
LALGIYGLIASLSFISLVWNNSVASVLAHAAAPAGTVFSAICLITGSVWGKGTWGTWWVW
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEEH
DARLTSMLILFFLYVGYLSLWSAFDNQARAEKSSAVFAIFSAINIPIVKFSVNLWSTLHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHH
PASIFRKGGVAIEGSLLLPLIAMFIFCTTLFLVVWILNALHLINLQKIKREISMRY
HHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFLLKPTNFTSFTKKALPWLGVICFACFLIGMFLALFFSPGDYKQGEIVRIMYLHVPSAW
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCHHH
LALGIYGLIASLSFISLVWNNSVASVLAHAAAPAGTVFSAICLITGSVWGKGTWGTWWVW
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEEH
DARLTSMLILFFLYVGYLSLWSAFDNQARAEKSSAVFAIFSAINIPIVKFSVNLWSTLHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHH
PASIFRKGGVAIEGSLLLPLIAMFIFCTTLFLVVWILNALHLINLQKIKREISMRY
HHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]