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The map label for this gene is tkt [H]

Identifier: 190570679

GI number: 190570679

Start: 240458

End: 242422

Strand: Reverse

Name: tkt [H]

Synonym: WPa_0229

Alternate gene names: 190570679

Gene position: 242422-240458 (Counterclockwise)

Preceding gene: 190570687

Following gene: 190570677

Centisome position: 16.35

GC content: 38.37

Gene sequence:

>1965_bases
ATGAATCATCTACTACTAAAATCCATGGCAAATGCTGTCCGCTTTTTATCAATTGATGCAGTACAAAAAGCAAATTCTGG
ACATCCAGGTATGCCACTTGGCATGGCAGATGTTGCCACTGTATTATTTGCTAAATATCTAAACCATAACCCTGATGATT
CTCAATGGATCAGTAGAGATCGTTTCGTCCTATCAAATGGTCACGGTTCAATGTTGCAATACTCTATATTATATCTGACA
GGCTACATTAGTATAGATGAACTAAAAAACTTCAGGCAACTTACATCAAAAACTCCAGGTCACCCAGAATTTGGCTTAAC
TTCTGGTATAGAAGCAACAACAGGCCCGCTTGGTCAGGGATTTGCCACTGCTGTTGGCATGGCACTTGCTGAATCGATTC
TTGAAAAGCAGTTTGAAATCAGTCACTACACTTATGTAATGCTAGGAGATGGTTGTCTTATGGAAGGTATAAGCCATGAA
GCAGCGTCCCTTGCTGGGCATCTTAAATTAAATAAGCTGATAGCACTTTTTGACGACAATGACATCTCTATAGACGGTTC
TACTAGCCTCTCTTGCTCTGATGATGTAGAAAAGCGTTTTTCAGCGTATGGATGGAATGTTGACAAAATCGATGGGCATG
ACTTTGATGCTATATCCCTTGCAATAGAGCAGGCGCAAAAGTCTGATAAACCTACACTAATCTGTTGCAAAACTATTATC
GGAAAATTTTCGAGCCGTGCTGGCACATCTTCTGCTCATAGTGGTGCCTTTACAGAGGAAGATGTAAAACAGATGAGAGA
AAAATTAAATTGGGACTATGAACCATTTCATGTACCAGAAGATGTGAGAAACGCTTGGATAGAAACAGTTAAGAGGGCAA
AGCAAAACTATACATCCTTGATCAATAAAGAACTACAAAGAAGACTTGAGAAACGTTTGCCGAATAATATCGAGAGTGAT
TTGGCTGATCTGAAGAAACAAATATGTAAGCTAATGCCAAACGAAGCTACTCGATCTTCTTTCGGCAGAGTAATGGAACT
ATTAACTAAGTCTATGCCAGAACTAATTGGTGGCTCTGCTGATCTTACCGGTTCAAATTGTACTAAATATAAGCATATGC
AGGCAATAGATAGTAATAATTATAGTGGCTCTTATGTACACTATGGAGTGAGAGAGCACGCTATGGCAGTTTGTATGAAT
GGTATGGCTCTTCATGGTGGGATTATTCCTTATGGTGGAACTTTTTTAGTATTTTCCGACTACTGCCGCCCTGCTATACG
TCTTTCAGCCTTGATGAAACAGCAGGTTATATATGTAATGACTCATGACTCAATTGGAGTAGGAGAAGATGGTCCAACTC
ACCAGCCAATAGAGCATTTAGCTTCTCTGAGAGCTATACCAAATCTGTATGTTTTTAGGCCAGCAGATGCAATTGAAACT
TTGGAGTGCATTAGCATTGCACTTGAAAAAAAAGAGTCACCTGCACTATTTGCGCTTTCAAGGCAAAATATTAATTACAT
GCACTCTTATACTGACCAATTGGCCAACCTATCAAAATTTGGTGCATATATACTATGCGAATATTCAGGGAAGCTAGAAG
TGACGATATTTGCTACCGGATCTGAAGTTGAAATTGCAGTTGAGGCAAGAGAAAAATTACAGGAAAAAGGTGTAGGTACA
AGGGTCATTTCTATGCCGTGTTGGAGGCTTTTTGACGAGCAAAGTGATGAATATAAAGGGGTAATATTAAATAATGATAG
TATTAAAGTTGCAATTGAAGCTGGAAGTGAAGTGGGTTGGCATAAATATATAGGTTCAAACGGTATATTTATTGGCATGA
AAAATTTTGGAGAATCAGCACCTTATGAAGCTCTTTATAAGCATTTTAATATTAGCGCTGATTATGTAGTAAAATGTGTT
TGTGAAAACGCTTTTTATCATTCCACTGCCCATAAAATTACTTAA

Upstream 100 bases:

>100_bases
CAATCTAACTATAAATTATTAATGATTTTAACATTAAGTGTCAACTTGTTTTTGCCACTATGATATAGTATACTTCACTT
TTAAGTTTTCCTATTAATAC

Downstream 100 bases:

>100_bases
TGAACTCAGCCAGTGCCGTTATTATGATATATATAACAATTTTACAAAAATAATATCATAGAATTCAAGAATTGCTACGT
GCTAAAAAAAGCAAAATGCT

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MNHLLLKSMANAVRFLSIDAVQKANSGHPGMPLGMADVATVLFAKYLNHNPDDSQWISRDRFVLSNGHGSMLQYSILYLT
GYISIDELKNFRQLTSKTPGHPEFGLTSGIEATTGPLGQGFATAVGMALAESILEKQFEISHYTYVMLGDGCLMEGISHE
AASLAGHLKLNKLIALFDDNDISIDGSTSLSCSDDVEKRFSAYGWNVDKIDGHDFDAISLAIEQAQKSDKPTLICCKTII
GKFSSRAGTSSAHSGAFTEEDVKQMREKLNWDYEPFHVPEDVRNAWIETVKRAKQNYTSLINKELQRRLEKRLPNNIESD
LADLKKQICKLMPNEATRSSFGRVMELLTKSMPELIGGSADLTGSNCTKYKHMQAIDSNNYSGSYVHYGVREHAMAVCMN
GMALHGGIIPYGGTFLVFSDYCRPAIRLSALMKQQVIYVMTHDSIGVGEDGPTHQPIEHLASLRAIPNLYVFRPADAIET
LECISIALEKKESPALFALSRQNINYMHSYTDQLANLSKFGAYILCEYSGKLEVTIFATGSEVEIAVEAREKLQEKGVGT
RVISMPCWRLFDEQSDEYKGVILNNDSIKVAIEAGSEVGWHKYIGSNGIFIGMKNFGESAPYEALYKHFNISADYVVKCV
CENAFYHSTAHKIT

Sequences:

>Translated_654_residues
MNHLLLKSMANAVRFLSIDAVQKANSGHPGMPLGMADVATVLFAKYLNHNPDDSQWISRDRFVLSNGHGSMLQYSILYLT
GYISIDELKNFRQLTSKTPGHPEFGLTSGIEATTGPLGQGFATAVGMALAESILEKQFEISHYTYVMLGDGCLMEGISHE
AASLAGHLKLNKLIALFDDNDISIDGSTSLSCSDDVEKRFSAYGWNVDKIDGHDFDAISLAIEQAQKSDKPTLICCKTII
GKFSSRAGTSSAHSGAFTEEDVKQMREKLNWDYEPFHVPEDVRNAWIETVKRAKQNYTSLINKELQRRLEKRLPNNIESD
LADLKKQICKLMPNEATRSSFGRVMELLTKSMPELIGGSADLTGSNCTKYKHMQAIDSNNYSGSYVHYGVREHAMAVCMN
GMALHGGIIPYGGTFLVFSDYCRPAIRLSALMKQQVIYVMTHDSIGVGEDGPTHQPIEHLASLRAIPNLYVFRPADAIET
LECISIALEKKESPALFALSRQNINYMHSYTDQLANLSKFGAYILCEYSGKLEVTIFATGSEVEIAVEAREKLQEKGVGT
RVISMPCWRLFDEQSDEYKGVILNNDSIKVAIEAGSEVGWHKYIGSNGIFIGMKNFGESAPYEALYKHFNISADYVVKCV
CENAFYHSTAHKIT
>Mature_654_residues
MNHLLLKSMANAVRFLSIDAVQKANSGHPGMPLGMADVATVLFAKYLNHNPDDSQWISRDRFVLSNGHGSMLQYSILYLT
GYISIDELKNFRQLTSKTPGHPEFGLTSGIEATTGPLGQGFATAVGMALAESILEKQFEISHYTYVMLGDGCLMEGISHE
AASLAGHLKLNKLIALFDDNDISIDGSTSLSCSDDVEKRFSAYGWNVDKIDGHDFDAISLAIEQAQKSDKPTLICCKTII
GKFSSRAGTSSAHSGAFTEEDVKQMREKLNWDYEPFHVPEDVRNAWIETVKRAKQNYTSLINKELQRRLEKRLPNNIESD
LADLKKQICKLMPNEATRSSFGRVMELLTKSMPELIGGSADLTGSNCTKYKHMQAIDSNNYSGSYVHYGVREHAMAVCMN
GMALHGGIIPYGGTFLVFSDYCRPAIRLSALMKQQVIYVMTHDSIGVGEDGPTHQPIEHLASLRAIPNLYVFRPADAIET
LECISIALEKKESPALFALSRQNINYMHSYTDQLANLSKFGAYILCEYSGKLEVTIFATGSEVEIAVEAREKLQEKGVGT
RVISMPCWRLFDEQSDEYKGVILNNDSIKVAIEAGSEVGWHKYIGSNGIFIGMKNFGESAPYEALYKHFNISADYVVKCV
CENAFYHSTAHKIT

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=647, Percent_Identity=25.193199381762, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI4507521, Length=647, Percent_Identity=25.193199381762, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI133778974, Length=561, Percent_Identity=27.6292335115865, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI225637459, Length=563, Percent_Identity=24.1563055062167, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI225637463, Length=483, Percent_Identity=24.8447204968944, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI225637461, Length=483, Percent_Identity=24.8447204968944, Blast_Score=127, Evalue=3e-29,
Organism=Escherichia coli, GI48994911, Length=664, Percent_Identity=48.4939759036145, Blast_Score=625, Evalue=1e-180,
Organism=Escherichia coli, GI1788808, Length=657, Percent_Identity=47.6407914764079, Blast_Score=602, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI17539652, Length=653, Percent_Identity=25.7274119448698, Blast_Score=181, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6325331, Length=674, Percent_Identity=45.1038575667656, Blast_Score=523, Evalue=1e-149,
Organism=Saccharomyces cerevisiae, GI6319593, Length=670, Percent_Identity=44.0298507462687, Blast_Score=502, Evalue=1e-143,
Organism=Drosophila melanogaster, GI45551847, Length=668, Percent_Identity=26.7964071856287, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI45550715, Length=668, Percent_Identity=26.7964071856287, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24666278, Length=497, Percent_Identity=27.9678068410463, Blast_Score=167, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24645119, Length=634, Percent_Identity=26.1829652996845, Blast_Score=159, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 72507; Mature: 72507

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHLLLKSMANAVRFLSIDAVQKANSGHPGMPLGMADVATVLFAKYLNHNPDDSQWISRD
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCC
RFVLSNGHGSMLQYSILYLTGYISIDELKNFRQLTSKTPGHPEFGLTSGIEATTGPLGQG
CEEEECCCCCHHHEEEEHHEECEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCH
FATAVGMALAESILEKQFEISHYTYVMLGDGCLMEGISHEAASLAGHLKLNKLIALFDDN
HHHHHHHHHHHHHHHHHHHHCEEEEEEECCCHHHHCCCHHHHHHHHHEEEEEEEEEECCC
DISIDGSTSLSCSDDVEKRFSAYGWNVDKIDGHDFDAISLAIEQAQKSDKPTLICCKTII
CEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEHHHHH
GKFSSRAGTSSAHSGAFTEEDVKQMREKLNWDYEPFHVPEDVRNAWIETVKRAKQNYTSL
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
INKELQRRLEKRLPNNIESDLADLKKQICKLMPNEATRSSFGRVMELLTKSMPELIGGSA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
DLTGSNCTKYKHMQAIDSNNYSGSYVHYGVREHAMAVCMNGMALHGGIIPYGGTFLVFSD
CCCCCCCHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHCCEEEECCCCCCCCEEEEEHH
YCRPAIRLSALMKQQVIYVMTHDSIGVGEDGPTHQPIEHLASLRAIPNLYVFRPADAIET
HCCHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCHHHHH
LECISIALEKKESPALFALSRQNINYMHSYTDQLANLSKFGAYILCEYSGKLEVTIFATG
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEEEEEC
SEVEIAVEAREKLQEKGVGTRVISMPCWRLFDEQSDEYKGVILNNDSIKVAIEAGSEVGW
CCEEEEHHHHHHHHHCCCCEEEECCHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCH
HKYIGSNGIFIGMKNFGESAPYEALYKHFNISADYVVKCVCENAFYHSTAHKIT
HHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNHLLLKSMANAVRFLSIDAVQKANSGHPGMPLGMADVATVLFAKYLNHNPDDSQWISRD
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCC
RFVLSNGHGSMLQYSILYLTGYISIDELKNFRQLTSKTPGHPEFGLTSGIEATTGPLGQG
CEEEECCCCCHHHEEEEHHEECEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCH
FATAVGMALAESILEKQFEISHYTYVMLGDGCLMEGISHEAASLAGHLKLNKLIALFDDN
HHHHHHHHHHHHHHHHHHHHCEEEEEEECCCHHHHCCCHHHHHHHHHEEEEEEEEEECCC
DISIDGSTSLSCSDDVEKRFSAYGWNVDKIDGHDFDAISLAIEQAQKSDKPTLICCKTII
CEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEHHHHH
GKFSSRAGTSSAHSGAFTEEDVKQMREKLNWDYEPFHVPEDVRNAWIETVKRAKQNYTSL
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
INKELQRRLEKRLPNNIESDLADLKKQICKLMPNEATRSSFGRVMELLTKSMPELIGGSA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
DLTGSNCTKYKHMQAIDSNNYSGSYVHYGVREHAMAVCMNGMALHGGIIPYGGTFLVFSD
CCCCCCCHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHCCEEEECCCCCCCCEEEEEHH
YCRPAIRLSALMKQQVIYVMTHDSIGVGEDGPTHQPIEHLASLRAIPNLYVFRPADAIET
HCCHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCHHHHH
LECISIALEKKESPALFALSRQNINYMHSYTDQLANLSKFGAYILCEYSGKLEVTIFATG
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEEEEEC
SEVEIAVEAREKLQEKGVGTRVISMPCWRLFDEQSDEYKGVILNNDSIKVAIEAGSEVGW
CCEEEEHHHHHHHHHCCCCEEEECCHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCH
HKYIGSNGIFIGMKNFGESAPYEALYKHFNISADYVVKCVCENAFYHSTAHKIT
HHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA