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The map label for this gene is dnaJ [H]

Identifier: 190570648

GI number: 190570648

Start: 201722

End: 202936

Strand: Reverse

Name: dnaJ [H]

Synonym: WPa_0195

Alternate gene names: 190570648

Gene position: 202936-201722 (Counterclockwise)

Preceding gene: 190570649

Following gene: 190570646

Centisome position: 13.69

GC content: 31.77

Gene sequence:

>1215_bases
TTGAAATTTTGGGTTACGTTTAATTTAACATATTTCAGTGGGGAATTTATTGTAGGTAGAAAGGAAGCTTTAAAAATATT
AGGTTTTCAATCAAGCGATGCGCCCAGTGAACAAGAAATTAAATCAGCGTATAGAAAATTAGCCTTGAAATATCATCCTG
ATAAACATTCAGGTAAAAATGAGGTTGTGAAGAAACAAAATGAAGAAAAATTTAAGCAGCTAGGTTCTGCATATGAATTT
CTTACTAAGGAAAGCATAGAAGAGGTTACAAATCTAACTGACGAAAATTTAAATGAAATTAATTCGCCTGGAGATTTGAG
GTTTTACTTAAGTAGGGCTCTATATAATCAGGATATAAAGTTTCTTGAAAAGCTTTTTTCCAAATTCAAAAGCAGTAAAG
ATGGAAGATTTGGTGATTACATCAATGAAAAACTTATTTATATTTACTTTCCATTATCTATTGCTTTAATGCAAGCTAAA
GATTCAAGAAATTATAGTATTTTGAAACTTCTTTTAGAAAATGGTGCTGATCCTAATATAAAGCTATTACATAATGAAGC
TTCGTTATACTATTGTAGGGTTATCGATGACAGCAGAATTGTAGAGTTATTGTTACAATATGGTGCTGATTCTAATATGT
TAGATAAAAATGGTAAAAATCCGTTGTTTAAAGCGTTTTTGTGTGATGATGATCATACTATGGAAATACTTTTGAAATAT
GGTGCTAATCCTAATATGTTAGATAAAAATGGTCGAGTTCCATTATATCAAGCAATCAATTGTGACAACGATAAACGCGA
AAAATATGTAGAGTTGCTTCTAAAGTATGGTGCAGATCCTAATCAGAAGGTTAATGGCTCCAGAGTTATAGAGTGTGCTC
CATATTTCACTAATAATTGTGTAATGAATTTGATTAAAACGCTTACTCTGCCATACGGCAGCAATAACAAAGTTAGAAAA
TTAATGGCCGAGTATGGTGGTGTTGATAGACAGTATATTATGCTTCAAGCAATATTTACTTGTTGTTGCTTAACAGTAGC
TTCTGCTACTTTTTTTAGTATAGCTTCTCCTTGGTGTTATATACCAACAGCAATATTTGCACTTGCCGCGTGTTTTTTCA
TTAAAAATGCTGTACATGCTGCATTTTTTGCAAAAGAACCTTCTACTGAGTTTACCGAAGCTAGAGCTTGTCCAGAGATT
AGTAAAAGGCTATAA

Upstream 100 bases:

>100_bases
GTATAGAGATGTTATTCCAGTATCAAGGACTGAAGTTTCCTGATCTACAATATTTGTACAGTTATGAAATAGATGCAATT
TGACATAAAAGCTTTACTTT

Downstream 100 bases:

>100_bases
TATCTAAAGTTTTAGTGCTGGGTAAAGATGAGAAAAAAGCATCCAGCAGACCTAAGTCAAAGGGAATGGACAAGAATAGA
AAGCTATTCCAGAGTATCAT

Product: Ankyrin repeat domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKFWVTFNLTYFSGEFIVGRKEALKILGFQSSDAPSEQEIKSAYRKLALKYHPDKHSGKNEVVKKQNEEKFKQLGSAYEF
LTKESIEEVTNLTDENLNEINSPGDLRFYLSRALYNQDIKFLEKLFSKFKSSKDGRFGDYINEKLIYIYFPLSIALMQAK
DSRNYSILKLLLENGADPNIKLLHNEASLYYCRVIDDSRIVELLLQYGADSNMLDKNGKNPLFKAFLCDDDHTMEILLKY
GANPNMLDKNGRVPLYQAINCDNDKREKYVELLLKYGADPNQKVNGSRVIECAPYFTNNCVMNLIKTLTLPYGSNNKVRK
LMAEYGGVDRQYIMLQAIFTCCCLTVASATFFSIASPWCYIPTAIFALAACFFIKNAVHAAFFAKEPSTEFTEARACPEI
SKRL

Sequences:

>Translated_404_residues
MKFWVTFNLTYFSGEFIVGRKEALKILGFQSSDAPSEQEIKSAYRKLALKYHPDKHSGKNEVVKKQNEEKFKQLGSAYEF
LTKESIEEVTNLTDENLNEINSPGDLRFYLSRALYNQDIKFLEKLFSKFKSSKDGRFGDYINEKLIYIYFPLSIALMQAK
DSRNYSILKLLLENGADPNIKLLHNEASLYYCRVIDDSRIVELLLQYGADSNMLDKNGKNPLFKAFLCDDDHTMEILLKY
GANPNMLDKNGRVPLYQAINCDNDKREKYVELLLKYGADPNQKVNGSRVIECAPYFTNNCVMNLIKTLTLPYGSNNKVRK
LMAEYGGVDRQYIMLQAIFTCCCLTVASATFFSIASPWCYIPTAIFALAACFFIKNAVHAAFFAKEPSTEFTEARACPEI
SKRL
>Mature_404_residues
MKFWVTFNLTYFSGEFIVGRKEALKILGFQSSDAPSEQEIKSAYRKLALKYHPDKHSGKNEVVKKQNEEKFKQLGSAYEF
LTKESIEEVTNLTDENLNEINSPGDLRFYLSRALYNQDIKFLEKLFSKFKSSKDGRFGDYINEKLIYIYFPLSIALMQAK
DSRNYSILKLLLENGADPNIKLLHNEASLYYCRVIDDSRIVELLLQYGADSNMLDKNGKNPLFKAFLCDDDHTMEILLKY
GANPNMLDKNGRVPLYQAINCDNDKREKYVELLLKYGADPNQKVNGSRVIECAPYFTNNCVMNLIKTLTLPYGSNNKVRK
LMAEYGGVDRQYIMLQAIFTCCCLTVASATFFSIASPWCYIPTAIFALAACFFIKNAVHAAFFAKEPSTEFTEARACPEI
SKRL

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI30348954, Length=213, Percent_Identity=25.3521126760563, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24650843, Length=130, Percent_Identity=36.9230769230769, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 46212; Mature: 46212

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS50088 ANK_REPEAT ; PS50297 ANK_REP_REGION ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFWVTFNLTYFSGEFIVGRKEALKILGFQSSDAPSEQEIKSAYRKLALKYHPDKHSGKN
CEEEEEEEEEEEECCEEECHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCHH
EVVKKQNEEKFKQLGSAYEFLTKESIEEVTNLTDENLNEINSPGDLRFYLSRALYNQDIK
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
FLEKLFSKFKSSKDGRFGDYINEKLIYIYFPLSIALMQAKDSRNYSILKLLLENGADPNI
HHHHHHHHHCCCCCCCCHHHHCCCEEEEEEHHHHHEECCCCCCCHHHHHHHHHCCCCCCE
KLLHNEASLYYCRVIDDSRIVELLLQYGADSNMLDKNGKNPLFKAFLCDDDHTMEILLKY
EEEECCCCEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHEEC
GANPNMLDKNGRVPLYQAINCDNDKREKYVELLLKYGADPNQKVNGSRVIECAPYFTNNC
CCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHH
VMNLIKTLTLPYGSNNKVRKLMAEYGGVDRQYIMLQAIFTCCCLTVASATFFSIASPWCY
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IPTAIFALAACFFIKNAVHAAFFAKEPSTEFTEARACPEISKRL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHCC
>Mature Secondary Structure
MKFWVTFNLTYFSGEFIVGRKEALKILGFQSSDAPSEQEIKSAYRKLALKYHPDKHSGKN
CEEEEEEEEEEEECCEEECHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCHH
EVVKKQNEEKFKQLGSAYEFLTKESIEEVTNLTDENLNEINSPGDLRFYLSRALYNQDIK
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
FLEKLFSKFKSSKDGRFGDYINEKLIYIYFPLSIALMQAKDSRNYSILKLLLENGADPNI
HHHHHHHHHCCCCCCCCHHHHCCCEEEEEEHHHHHEECCCCCCCHHHHHHHHHCCCCCCE
KLLHNEASLYYCRVIDDSRIVELLLQYGADSNMLDKNGKNPLFKAFLCDDDHTMEILLKY
EEEECCCCEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHEEC
GANPNMLDKNGRVPLYQAINCDNDKREKYVELLLKYGADPNQKVNGSRVIECAPYFTNNC
CCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHH
VMNLIKTLTLPYGSNNKVRKLMAEYGGVDRQYIMLQAIFTCCCLTVASATFFSIASPWCY
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IPTAIFALAACFFIKNAVHAAFFAKEPSTEFTEARACPEISKRL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7569993; 8253680 [H]