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The map label for this gene is ubiG [H]

Identifier: 190570641

GI number: 190570641

Start: 193212

End: 194378

Strand: Direct

Name: ubiG [H]

Synonym: WPa_0183

Alternate gene names: 190570641

Gene position: 193212-194378 (Clockwise)

Preceding gene: 190570638

Following gene: 190570642

Centisome position: 13.03

GC content: 36.68

Gene sequence:

>1167_bases
ATGTCAGATGTGATATCAGTTGCTTCAGACCACGCAGGTTATGAACTAAAATCAGAAATAAAGGCTTACTTGGAAACTTT
AGATTATACAGTGATAGACCGTGGCTGCACTGCTGAACAAAAGAGTGTAGACTACCCTGACTATGCTGCTGAAGTTGTAG
AAGATATAACAAACAAAAAAGCAAATTATGGAATATTAATTTGCGGTACAGGTTTGGGCATGAGTACTGTGGCAAATCGT
TTTGAAGGAATCTACGCTGCTTTATGTAATAGTGTTGAGATCGCAAAATTAGCTCGCGAGCATGGCAACGCGAATATACT
TTGTCTTGGTGCAGGGTTTACTGCGAGTGGATTAGCAAAAGACATAGTCAAACAATTCCTCGAAACAGAATTTTCAAAAG
AAAGTAGACATAAAGAACGCCTTGATAAACTTAGCAATATTAGCAAGAAAAAAACCACAAAAACTTATAACGAAGATGAA
ATATCAAAATTCGCTAAAATAGCAGGTGAATGGTGGAATGAGAATGGCAAATTCAAGCCATTGCACATGATGAATCCTGT
GAGAGTATCATACATCGTTGAGAAAATAAAAGAATTAAAAAAATGCGATTTAAAAGAACTATCATTGCTCGATGTTGGTT
GTGGTGGTGGCATTTTGTCAGAGTCAATGGCGCGTATTGGTATTAGCGTTGCAGGAATAGATGTATGTGAGGAAAACATA
AAAGTGGCACAGTTGCATGCGAAGAAAGTAGGGTTAAATATAGAATACACACACACTAGCATTGAAGAGCTAAGCAATGA
CAAGAAGTATGACGTGGTTTTGTTGATGGAAGTGGTTGAACATGTCGATAATTTAGAGTTTTTCATGAAAAAAGCAATAG
AGCTGTTGAAGCCAGAAGGGCTAATTTTTATATCGACGATAAATAGAACTATTAAATCCTTCTGTCTTGCAATAGTCGGC
GCAGAGTACATATTAAACTGGCTGCCAAAAGGCACACATAATTGGAATAAATTTCTCAAGCCATCAGAAATTGCAAATCA
TCTAAGGGAAAACAACGTAATACTGCAAAACATGGCTGGTATGGAATATAATGTAATAAAGCGTGAATGGAACTTGACCA
AAGGTGTGGATGTTAATTATATACTTTGTGGAAACGTTGTAACTTGA

Upstream 100 bases:

>100_bases
GCATATCTGACTCGAAATTTATTCAGAAAGATCAGAAGAGCTTGACAAAAAGCTCAAAATAAATTACCCATATAAATACC
CTTAAGTTGCAATTTCTTAT

Downstream 100 bases:

>100_bases
AATCTCATTCAAGTACTAGAAGGTAATGCAAATATTCTAGGCAGTTTTACTTTACTTAGCAGCTAATTTATCATATGTAT
TTCCATAGGGTATCGCTATA

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSDVISVASDHAGYELKSEIKAYLETLDYTVIDRGCTAEQKSVDYPDYAAEVVEDITNKKANYGILICGTGLGMSTVANR
FEGIYAALCNSVEIAKLAREHGNANILCLGAGFTASGLAKDIVKQFLETEFSKESRHKERLDKLSNISKKKTTKTYNEDE
ISKFAKIAGEWWNENGKFKPLHMMNPVRVSYIVEKIKELKKCDLKELSLLDVGCGGGILSESMARIGISVAGIDVCEENI
KVAQLHAKKVGLNIEYTHTSIEELSNDKKYDVVLLMEVVEHVDNLEFFMKKAIELLKPEGLIFISTINRTIKSFCLAIVG
AEYILNWLPKGTHNWNKFLKPSEIANHLRENNVILQNMAGMEYNVIKREWNLTKGVDVNYILCGNVVT

Sequences:

>Translated_388_residues
MSDVISVASDHAGYELKSEIKAYLETLDYTVIDRGCTAEQKSVDYPDYAAEVVEDITNKKANYGILICGTGLGMSTVANR
FEGIYAALCNSVEIAKLAREHGNANILCLGAGFTASGLAKDIVKQFLETEFSKESRHKERLDKLSNISKKKTTKTYNEDE
ISKFAKIAGEWWNENGKFKPLHMMNPVRVSYIVEKIKELKKCDLKELSLLDVGCGGGILSESMARIGISVAGIDVCEENI
KVAQLHAKKVGLNIEYTHTSIEELSNDKKYDVVLLMEVVEHVDNLEFFMKKAIELLKPEGLIFISTINRTIKSFCLAIVG
AEYILNWLPKGTHNWNKFLKPSEIANHLRENNVILQNMAGMEYNVIKREWNLTKGVDVNYILCGNVVT
>Mature_387_residues
SDVISVASDHAGYELKSEIKAYLETLDYTVIDRGCTAEQKSVDYPDYAAEVVEDITNKKANYGILICGTGLGMSTVANRF
EGIYAALCNSVEIAKLAREHGNANILCLGAGFTASGLAKDIVKQFLETEFSKESRHKERLDKLSNISKKKTTKTYNEDEI
SKFAKIAGEWWNENGKFKPLHMMNPVRVSYIVEKIKELKKCDLKELSLLDVGCGGGILSESMARIGISVAGIDVCEENIK
VAQLHAKKVGLNIEYTHTSIEELSNDKKYDVVLLMEVVEHVDNLEFFMKKAIELLKPEGLIFISTINRTIKSFCLAIVGA
EYILNWLPKGTHNWNKFLKPSEIANHLRENNVILQNMAGMEYNVIKREWNLTKGVDVNYILCGNVVT

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=236, Percent_Identity=39.4067796610169, Blast_Score=177, Evalue=2e-44,
Organism=Escherichia coli, GI1788564, Length=241, Percent_Identity=42.7385892116183, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1790528, Length=147, Percent_Identity=36.734693877551, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI115533050, Length=261, Percent_Identity=33.3333333333333, Blast_Score=151, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6324476, Length=273, Percent_Identity=30.4029304029304, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281365311, Length=250, Percent_Identity=32.4, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24585589, Length=236, Percent_Identity=33.0508474576271, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 43431; Mature: 43299

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVISVASDHAGYELKSEIKAYLETLDYTVIDRGCTAEQKSVDYPDYAAEVVEDITNKK
CCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
ANYGILICGTGLGMSTVANRFEGIYAALCNSVEIAKLAREHGNANILCLGAGFTASGLAK
CCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCHHHHHH
DIVKQFLETEFSKESRHKERLDKLSNISKKKTTKTYNEDEISKFAKIAGEWWNENGKFKP
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCE
LHMMNPVRVSYIVEKIKELKKCDLKELSLLDVGCGGGILSESMARIGISVAGIDVCEENI
ECCCCCHHHHHHHHHHHHHHHCCHHHHHEEEECCCCHHHHHHHHHHCCEEECHHHHHCCC
KVAQLHAKKVGLNIEYTHTSIEELSNDKKYDVVLLMEVVEHVDNLEFFMKKAIELLKPEG
HHHEEHHHHHCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LIFISTINRTIKSFCLAIVGAEYILNWLPKGTHNWNKFLKPSEIANHLRENNVILQNMAG
EEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHCCEEEECCCC
MEYNVIKREWNLTKGVDVNYILCGNVVT
CEEEHHHHHCCCCCCCCCCEEECCCCCC
>Mature Secondary Structure 
SDVISVASDHAGYELKSEIKAYLETLDYTVIDRGCTAEQKSVDYPDYAAEVVEDITNKK
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
ANYGILICGTGLGMSTVANRFEGIYAALCNSVEIAKLAREHGNANILCLGAGFTASGLAK
CCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCHHHHHH
DIVKQFLETEFSKESRHKERLDKLSNISKKKTTKTYNEDEISKFAKIAGEWWNENGKFKP
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCE
LHMMNPVRVSYIVEKIKELKKCDLKELSLLDVGCGGGILSESMARIGISVAGIDVCEENI
ECCCCCHHHHHHHHHHHHHHHCCHHHHHEEEECCCCHHHHHHHHHHCCEEECHHHHHCCC
KVAQLHAKKVGLNIEYTHTSIEELSNDKKYDVVLLMEVVEHVDNLEFFMKKAIELLKPEG
HHHEEHHHHHCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LIFISTINRTIKSFCLAIVGAEYILNWLPKGTHNWNKFLKPSEIANHLRENNVILQNMAG
EEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHCCEEEECCCC
MEYNVIKREWNLTKGVDVNYILCGNVVT
CEEEHHHHHCCCCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA