Click here to switch to the map view.

The map label for this gene is sglT [H]

Identifier: 189499241

GI number: 189499241

Start: 253671

End: 255077

Strand: Reverse

Name: sglT [H]

Synonym: Cphamn1_0261

Alternate gene names: 189499241

Gene position: 255077-253671 (Counterclockwise)

Preceding gene: 189499242

Following gene: 189499240

Centisome position: 9.32

GC content: 51.03

Gene sequence:

>1407_bases
ATGCAGACGCTCGATCTCATCATCATCATAGGCTTCCTTGCCGCAATGGCCGGATACGGGATCTGGCAGGGACACACCAA
CCGGACTACCGGTGATTACTTCCTCGGGGGGCGCAACCTCCCCTGGATCGTCGCCATGTTTTCCATTGTTGCCACTGAAA
CTTCGGTACTGACTTTCGTCAGCATCCCAGGTATAGCGTTCAGGGGTGACTGGACTTTTCTGCAGCTCGCTATGGGTTAT
ATCATCGGCAGAATGCTGGTCAGCGCTGTGCTGCTTCCGATCTACTTCCGTCAAGGAGTCAGCTCGATTTATGAAGTAAT
CGGAAACCGTTTCGGCCCTCACATGCAAAAACTTGCCTCAACTGTTTTTCTGGTCACCAGAATTTTAGCTGACGGGGTAA
GGTTCCTTGCTACTGCTGTGGTCGTTGAAGCGGTAACCGGATGGTCCCTCTCAGCCTCGGTACTCATTATCGGTATCGTC
ACACTGGTTTATACGCTGTCGGGAGGAATACGAACAATCGTCTGGATCGACAGCATCCAGTTCGTCCTATATTTTGTCGG
CGGAATTATCACCATTGCGTTTATCGCCGCAAACCTCGATGTCGGACTACCCGAAGCGTTGGGAGCCCTTGCCAACGAAG
GCAAGCTGAAAGTGATCAATCATGACTGGCGCCTCTTTTCAGAGCCCTGGGCTTTCTTCAGCGCACTTACAGGAGGTATA
CTCCTTTCATTCGCGTCACATGGAGTTGACTATATGATGGTACAGCGCGTGCTCGGCTGCAAAAACCTCAGCGCGGCAAG
AAAAGCGATGATCGGAAGCGGATTTTTTGTATTCATTCAGTTCACTGTATTCCTGCTTGCCGGCTCGCTGATCTATCTTT
TTATCGGAGATGTTCAGATTGAAAAAGACCGTGAGTTCGCCTCTTTCATTGTCAACCACCTGCCTGTCGGCCTGAAAGGC
CTCCTGCTCGCAGGCGTGCTTTCGGCCGCAATGTCAACACTCAGCTCTTCAATTAACTCACTCGCTTCATCGACGGTAAC
CGATCTGCTGGGGGGCAACGCTTCACTGAAACGCTCCAGGTTGATAAGCCTCGGATGGGCAGCCGTACTCATCAGCATAG
CACTGGTATTTGATGAAAGCGACAACGCAATTGTCGTGCTGGGCCTTAAAATCGCATCTTTTACCTACGGAGGACTGCTC
GGCCTTTTCCTCCTTTCCGTTAGCGGCAAAGAGTTTCATGTTTTCAGCCTCTCGATGGGGCTGATAGCCGGGATGGGCAC
AGTATTCGTGCTGGATTATCTGACCTTTGCATGGACCTGGTACATAGCCGCCTCAGTCCTTGCCAACCTGCTTGTAGTCT
GGATTACCGAGACTGTTTTGAATAACAGTTTCATAAGACGATCGTAA

Upstream 100 bases:

>100_bases
AGCGGAAATCAGAGCATCATGGGCGGATGATGAACAGGAGTTTCTGTCCATCAAGCAGAACTATCATCTCTATCATTAAT
TCATTCCCGTAACTTACCGT

Downstream 100 bases:

>100_bases
AACACCTGATCTCGAAAGAATCTTTTTGTTCTAAAAAAATAATTCTATAGATTCCTATAAGGGAATTAAACTATTTAGCA
TCAGAAAAAGCAGGAGTTTC

Product: Na+/solute symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MQTLDLIIIIGFLAAMAGYGIWQGHTNRTTGDYFLGGRNLPWIVAMFSIVATETSVLTFVSIPGIAFRGDWTFLQLAMGY
IIGRMLVSAVLLPIYFRQGVSSIYEVIGNRFGPHMQKLASTVFLVTRILADGVRFLATAVVVEAVTGWSLSASVLIIGIV
TLVYTLSGGIRTIVWIDSIQFVLYFVGGIITIAFIAANLDVGLPEALGALANEGKLKVINHDWRLFSEPWAFFSALTGGI
LLSFASHGVDYMMVQRVLGCKNLSAARKAMIGSGFFVFIQFTVFLLAGSLIYLFIGDVQIEKDREFASFIVNHLPVGLKG
LLLAGVLSAAMSTLSSSINSLASSTVTDLLGGNASLKRSRLISLGWAAVLISIALVFDESDNAIVVLGLKIASFTYGGLL
GLFLLSVSGKEFHVFSLSMGLIAGMGTVFVLDYLTFAWTWYIAASVLANLLVVWITETVLNNSFIRRS

Sequences:

>Translated_468_residues
MQTLDLIIIIGFLAAMAGYGIWQGHTNRTTGDYFLGGRNLPWIVAMFSIVATETSVLTFVSIPGIAFRGDWTFLQLAMGY
IIGRMLVSAVLLPIYFRQGVSSIYEVIGNRFGPHMQKLASTVFLVTRILADGVRFLATAVVVEAVTGWSLSASVLIIGIV
TLVYTLSGGIRTIVWIDSIQFVLYFVGGIITIAFIAANLDVGLPEALGALANEGKLKVINHDWRLFSEPWAFFSALTGGI
LLSFASHGVDYMMVQRVLGCKNLSAARKAMIGSGFFVFIQFTVFLLAGSLIYLFIGDVQIEKDREFASFIVNHLPVGLKG
LLLAGVLSAAMSTLSSSINSLASSTVTDLLGGNASLKRSRLISLGWAAVLISIALVFDESDNAIVVLGLKIASFTYGGLL
GLFLLSVSGKEFHVFSLSMGLIAGMGTVFVLDYLTFAWTWYIAASVLANLLVVWITETVLNNSFIRRS
>Mature_468_residues
MQTLDLIIIIGFLAAMAGYGIWQGHTNRTTGDYFLGGRNLPWIVAMFSIVATETSVLTFVSIPGIAFRGDWTFLQLAMGY
IIGRMLVSAVLLPIYFRQGVSSIYEVIGNRFGPHMQKLASTVFLVTRILADGVRFLATAVVVEAVTGWSLSASVLIIGIV
TLVYTLSGGIRTIVWIDSIQFVLYFVGGIITIAFIAANLDVGLPEALGALANEGKLKVINHDWRLFSEPWAFFSALTGGI
LLSFASHGVDYMMVQRVLGCKNLSAARKAMIGSGFFVFIQFTVFLLAGSLIYLFIGDVQIEKDREFASFIVNHLPVGLKG
LLLAGVLSAAMSTLSSSINSLASSTVTDLLGGNASLKRSRLISLGWAAVLISIALVFDESDNAIVVLGLKIASFTYGGLL
GLFLLSVSGKEFHVFSLSMGLIAGMGTVFVLDYLTFAWTWYIAASVLANLLVVWITETVLNNSFIRRS

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI4507035, Length=416, Percent_Identity=27.4038461538462, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI157671931, Length=422, Percent_Identity=26.303317535545, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI256985183, Length=431, Percent_Identity=26.2180974477958, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI167466278, Length=361, Percent_Identity=26.8698060941828, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI110835708, Length=469, Percent_Identity=23.6673773987207, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI4507033, Length=400, Percent_Identity=24.25, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI206597483, Length=374, Percent_Identity=25.9358288770053, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4507031, Length=454, Percent_Identity=24.0088105726872, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI14140236, Length=391, Percent_Identity=25.0639386189258, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI109659836, Length=488, Percent_Identity=22.7459016393443, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI206597487, Length=393, Percent_Identity=23.9185750636132, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI109659839, Length=504, Percent_Identity=21.2301587301587, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI17941285, Length=391, Percent_Identity=22.5063938618926, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790113, Length=365, Percent_Identity=23.8356164383562, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082237, Length=376, Percent_Identity=24.468085106383, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533094, Length=348, Percent_Identity=28.448275862069, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI32566512, Length=280, Percent_Identity=27.1428571428571, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533096, Length=215, Percent_Identity=30.6976744186047, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573698, Length=417, Percent_Identity=25.8992805755396, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24651741, Length=433, Percent_Identity=24.2494226327945, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24641117, Length=404, Percent_Identity=26.7326732673267, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24651739, Length=438, Percent_Identity=25.3424657534247, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24640370, Length=394, Percent_Identity=25.8883248730964, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI221459584, Length=405, Percent_Identity=28.3950617283951, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24645928, Length=363, Percent_Identity=26.4462809917355, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281362918, Length=288, Percent_Identity=23.2638888888889, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24650192, Length=412, Percent_Identity=26.2135922330097, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28574994, Length=435, Percent_Identity=23.448275862069, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI221459588, Length=409, Percent_Identity=26.4058679706601, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI281364280, Length=370, Percent_Identity=24.5945945945946, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI19920916, Length=404, Percent_Identity=25.990099009901, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI161076631, Length=389, Percent_Identity=24.1645244215938, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI221459586, Length=411, Percent_Identity=25.7907542579075, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281362054, Length=348, Percent_Identity=24.7126436781609, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI281362052, Length=348, Percent_Identity=24.7126436781609, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI281362050, Length=348, Percent_Identity=24.7126436781609, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648056, Length=348, Percent_Identity=24.7126436781609, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356827, Length=348, Percent_Identity=24.7126436781609, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI221379702, Length=408, Percent_Identity=22.5490196078431, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 50557; Mature: 50557

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLDLIIIIGFLAAMAGYGIWQGHTNRTTGDYFLGGRNLPWIVAMFSIVATETSVLTFV
CCHHHHHHHHHHHHHHHCCCEECCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHEEEE
SIPGIAFRGDWTFLQLAMGYIIGRMLVSAVLLPIYFRQGVSSIYEVIGNRFGPHMQKLAS
ECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TVFLVTRILADGVRFLATAVVVEAVTGWSLSASVLIIGIVTLVYTLSGGIRTIVWIDSIQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHH
FVLYFVGGIITIAFIAANLDVGLPEALGALANEGKLKVINHDWRLFSEPWAFFSALTGGI
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
LLSFASHGVDYMMVQRVLGCKNLSAARKAMIGSGFFVFIQFTVFLLAGSLIYLFIGDVQI
HHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEE
EKDREFASFIVNHLPVGLKGLLLAGVLSAAMSTLSSSINSLASSTVTDLLGGNASLKRSR
ECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LISLGWAAVLISIALVFDESDNAIVVLGLKIASFTYGGLLGLFLLSVSGKEFHVFSLSMG
HHHHHHHHHHHHHHHEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHH
LIAGMGTVFVLDYLTFAWTWYIAASVLANLLVVWITETVLNNSFIRRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure
MQTLDLIIIIGFLAAMAGYGIWQGHTNRTTGDYFLGGRNLPWIVAMFSIVATETSVLTFV
CCHHHHHHHHHHHHHHHCCCEECCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHEEEE
SIPGIAFRGDWTFLQLAMGYIIGRMLVSAVLLPIYFRQGVSSIYEVIGNRFGPHMQKLAS
ECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TVFLVTRILADGVRFLATAVVVEAVTGWSLSASVLIIGIVTLVYTLSGGIRTIVWIDSIQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHH
FVLYFVGGIITIAFIAANLDVGLPEALGALANEGKLKVINHDWRLFSEPWAFFSALTGGI
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
LLSFASHGVDYMMVQRVLGCKNLSAARKAMIGSGFFVFIQFTVFLLAGSLIYLFIGDVQI
HHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEE
EKDREFASFIVNHLPVGLKGLLLAGVLSAAMSTLSSSINSLASSTVTDLLGGNASLKRSR
ECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LISLGWAAVLISIALVFDESDNAIVVLGLKIASFTYGGLLGLFLLSVSGKEFHVFSLSMG
HHHHHHHHHHHHHHHEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHH
LIAGMGTVFVLDYLTFAWTWYIAASVLANLLVVWITETVLNNSFIRRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]