BacMap

Definition	Chlorobium phaeobacteroides BS1 chromosome, complete genome.
Accession	NC_010831
Length	2,736,403

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The map label for this gene is ftsH [H]

Identifier: 189499094

GI number: 189499094

Start: 92669

End: 94729

Strand: Reverse

Name: ftsH [H]

Synonym: Cphamn1_0100

Alternate gene names: 189499094

Gene position: 94729-92669 (Counterclockwise)

Preceding gene: 189499100

Following gene: 189499093

Centisome position: 3.46

GC content: 49.98

Gene sequence:

>2061_bases
ATGCCAAACAACCTGTTTAAACCACAGAATCCCTATAAAAACGATCCTGAGAACAACGACAAAAAACCAAAATTCTCGCT
GCTCTACTATGTCGTCATTGTCCTGCTGCTTATAGGTCTGCAGCTGGCCTTCTTCTGGTCCGGCTCCTCCGAGGAAATCC
CCTACAGTGAATTCCGCAGCTATATAGAAGAAAATAAAATCGAGTCCGTAAAGATTGCGCCCGAGCGCATATACGTAAAC
CTGAAACCGGGCGTGATCCCGTCCGTCGCCAAAAACGGAGACGGCTCACTCTCTGCCGAACCCACTGAAGTGTACGTTAC
CCCGGTAGTGGACGACGGACTTATAGAGCTCCTTGAATCAAAAGGAATCAGTTATCAGGGTATACCCGGAAACACCTGGA
TCGGTGAACTGCTGCAATGGATTCTCCCGTTTGCCCTGCTGATCGGGATCTACTTCTTCGTCTTTCGCCGCCTTGGCGGA
CCGGGATCACAGTTCATGAACATCAGCAAGAACAAGGCCGCCCTTTATGAAAACCTCGATGAACATACCCGGATAACCTT
CAAGGATGTTGCGGGACTCGACGAAGCCAAGGCTGAAGTCATGGAAGTTGTCGGCTTCCTTAAAGACCCCAAGAAATACA
CGAAACTGGGCGGAAAACTTCCAAAAGGAGTGCTGCTCGTAGGTCCTCCGGGAACCGGCAAAACCCTTCTTGCCAAAGCG
GTTGCAGGAGAAGCTGATGTACCGTTTTTCAGCATCAGCGGTTCTGATTTTGTGGAAATGTTTGTCGGTGTCGGCGCGGC
AAGGGTACGCGACCTTTTCCGTGAGGCGAAAGAAAAAGCGCCCTGCATCATCTTTATTGACGAAATAGATGCCGTAGGAC
GCAGCCGGGGAAAAGGAGCCATGATGGGTGCTAATGATGAAAGGGAAAACACCCTTAACCAGCTGCTGGTGGAAATGGAT
GGTTTCGCAACAGACAAAGGGGTCATCCTCATGGCCGCGACCAATCGCCCCGACGTTCTGGATAATGCTCTTCTTCGACC
GGGACGGTTCGACCGCCAGATAATGGTTGACAAACCTGACCTGAAAGGACGTGTCGATACCTTCAAGGTTCATACCAAGA
AACTCTCTCTCTCGCCTGATGTCAACGTTAAGGTACTGGCTTCCCAGACTCCTGGGTTTGCCGGAGCCGAGATCGCCAAC
GCGGCCAACGAGGCTGCGCTGCTTGCCTCCAGACGAGGAAAGCAGAGTATTGAAATGAAAGACTTCGAGGATGCTATCGA
ACGGGTGGTCGCCGGTCTCGAAAAGAAAAACAAGGTAATTAATCCGAAAGAGAAAAAGGTAGTCGCCTATCACGAATCAG
GTCACGCGATCATCAGCTGGATGATGGCGGAAAATGACGCTGTGCAGAAAATATCGATTGTTCCACGGGGCATGAGCGCT
CTGGGCTATACGATGAACCTGCCGCTTGAAGATCGCTACCTGATGACAAAACACGAACTCTATTCACGTATCTGCGGACT
GCTGGGAGGAAGAATTGCCGAAGAAATCATCTTTGACGAAATCTCAACCGGCGCTCAGAATGATCTCGAAAAAATCACCG
AGATAGCATACAACATGGTGGTTGTCTACGGGATGAGCAAAAAACTGGGCAACATCTCTTACTATGAAAGCAACAACCCC
TATTACGGCGGGCCGGGCGTGGACAAAAAGTACAGTGAGCACACCGCGCGCCTGATAGATGAAGAGGTTCACCAGTTAAT
CGATCAGGCCCAGCAGCAGGTCAGGGAGATACTGACAGAAAATCACGACAAACTTGAAATGCTTGCGCAGGAACTGCTTA
AAAATGAAGTCCTCCACTATTGCAAAATCGAGGAGATTCTCGGCAGAAGACCAGGCGCAAGCGATGATGATGCAATGTCT
GAAGAGTGCGGCAAAAAAGCAGCTGATAGAGAAACCGGCCCTGACAGCAATGGAAAAACACCTGTTGATGAAGAGGAGCT
GAAAAATCTTGAAGCTGCTGTCGAAAAAATCAGGCAGAGCAAGAATGCGGAGGAAAACTGA

Upstream 100 bases:

>100_bases
CCGGTTTCTGCGCTCCGTTCGCCTTGCTCTTGAAACGCTCATGACAATACAGAGAGGCGCCCTTAACAGAATATATATTT
GCTAATTTTTTTACGAATTG

Downstream 100 bases:

>100_bases
GGCAAGAAAAGAATCAGGAAGCAGCCTGGGCCCTGTGAAATCCGAGCATCTGTTTCACAGGATGCATGACTTCAGAAATT
ACATGGAAAAAAGAGTTCTG

Product: ATP-dependent metalloprotease FtsH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 685

Protein sequence:

>686_residues
MPNNLFKPQNPYKNDPENNDKKPKFSLLYYVVIVLLLIGLQLAFFWSGSSEEIPYSEFRSYIEENKIESVKIAPERIYVN
LKPGVIPSVAKNGDGSLSAEPTEVYVTPVVDDGLIELLESKGISYQGIPGNTWIGELLQWILPFALLIGIYFFVFRRLGG
PGSQFMNISKNKAALYENLDEHTRITFKDVAGLDEAKAEVMEVVGFLKDPKKYTKLGGKLPKGVLLVGPPGTGKTLLAKA
VAGEADVPFFSISGSDFVEMFVGVGAARVRDLFREAKEKAPCIIFIDEIDAVGRSRGKGAMMGANDERENTLNQLLVEMD
GFATDKGVILMAATNRPDVLDNALLRPGRFDRQIMVDKPDLKGRVDTFKVHTKKLSLSPDVNVKVLASQTPGFAGAEIAN
AANEAALLASRRGKQSIEMKDFEDAIERVVAGLEKKNKVINPKEKKVVAYHESGHAIISWMMAENDAVQKISIVPRGMSA
LGYTMNLPLEDRYLMTKHELYSRICGLLGGRIAEEIIFDEISTGAQNDLEKITEIAYNMVVVYGMSKKLGNISYYESNNP
YYGGPGVDKKYSEHTARLIDEEVHQLIDQAQQQVREILTENHDKLEMLAQELLKNEVLHYCKIEEILGRRPGASDDDAMS
EECGKKAADRETGPDSNGKTPVDEEELKNLEAAVEKIRQSKNAEEN

Sequences:

>Translated_686_residues
MPNNLFKPQNPYKNDPENNDKKPKFSLLYYVVIVLLLIGLQLAFFWSGSSEEIPYSEFRSYIEENKIESVKIAPERIYVN
LKPGVIPSVAKNGDGSLSAEPTEVYVTPVVDDGLIELLESKGISYQGIPGNTWIGELLQWILPFALLIGIYFFVFRRLGG
PGSQFMNISKNKAALYENLDEHTRITFKDVAGLDEAKAEVMEVVGFLKDPKKYTKLGGKLPKGVLLVGPPGTGKTLLAKA
VAGEADVPFFSISGSDFVEMFVGVGAARVRDLFREAKEKAPCIIFIDEIDAVGRSRGKGAMMGANDERENTLNQLLVEMD
GFATDKGVILMAATNRPDVLDNALLRPGRFDRQIMVDKPDLKGRVDTFKVHTKKLSLSPDVNVKVLASQTPGFAGAEIAN
AANEAALLASRRGKQSIEMKDFEDAIERVVAGLEKKNKVINPKEKKVVAYHESGHAIISWMMAENDAVQKISIVPRGMSA
LGYTMNLPLEDRYLMTKHELYSRICGLLGGRIAEEIIFDEISTGAQNDLEKITEIAYNMVVVYGMSKKLGNISYYESNNP
YYGGPGVDKKYSEHTARLIDEEVHQLIDQAQQQVREILTENHDKLEMLAQELLKNEVLHYCKIEEILGRRPGASDDDAMS
EECGKKAADRETGPDSNGKTPVDEEELKNLEAAVEKIRQSKNAEEN
>Mature_685_residues
PNNLFKPQNPYKNDPENNDKKPKFSLLYYVVIVLLLIGLQLAFFWSGSSEEIPYSEFRSYIEENKIESVKIAPERIYVNL
KPGVIPSVAKNGDGSLSAEPTEVYVTPVVDDGLIELLESKGISYQGIPGNTWIGELLQWILPFALLIGIYFFVFRRLGGP
GSQFMNISKNKAALYENLDEHTRITFKDVAGLDEAKAEVMEVVGFLKDPKKYTKLGGKLPKGVLLVGPPGTGKTLLAKAV
AGEADVPFFSISGSDFVEMFVGVGAARVRDLFREAKEKAPCIIFIDEIDAVGRSRGKGAMMGANDERENTLNQLLVEMDG
FATDKGVILMAATNRPDVLDNALLRPGRFDRQIMVDKPDLKGRVDTFKVHTKKLSLSPDVNVKVLASQTPGFAGAEIANA
ANEAALLASRRGKQSIEMKDFEDAIERVVAGLEKKNKVINPKEKKVVAYHESGHAIISWMMAENDAVQKISIVPRGMSAL
GYTMNLPLEDRYLMTKHELYSRICGLLGGRIAEEIIFDEISTGAQNDLEKITEIAYNMVVVYGMSKKLGNISYYESNNPY
YGGPGVDKKYSEHTARLIDEEVHQLIDQAQQQVREILTENHDKLEMLAQELLKNEVLHYCKIEEILGRRPGASDDDAMSE
ECGKKAADRETGPDSNGKTPVDEEELKNLEAAVEKIRQSKNAEEN

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [H]

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]

Homologues:

Organism=Homo sapiens, GI300192933, Length=625, Percent_Identity=47.04, Blast_Score=515, Evalue=1e-146,
Organism=Homo sapiens, GI4507173, Length=621, Percent_Identity=42.1900161030596, Blast_Score=461, Evalue=1e-129,
Organism=Homo sapiens, GI21327685, Length=492, Percent_Identity=44.5121951219512, Blast_Score=398, Evalue=1e-110,
Organism=Homo sapiens, GI7657689, Length=494, Percent_Identity=44.331983805668, Blast_Score=398, Evalue=1e-110,
Organism=Homo sapiens, GI24497435, Length=256, Percent_Identity=43.75, Blast_Score=217, Evalue=3e-56,
Organism=Homo sapiens, GI4506209, Length=260, Percent_Identity=42.3076923076923, Blast_Score=206, Evalue=8e-53,
Organism=Homo sapiens, GI21361144, Length=254, Percent_Identity=42.5196850393701, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI6005942, Length=240, Percent_Identity=41.6666666666667, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI195539395, Length=246, Percent_Identity=39.8373983739837, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI89064750, Length=260, Percent_Identity=41.1538461538462, Blast_Score=190, Evalue=4e-48,
Organism=Homo sapiens, GI5729991, Length=260, Percent_Identity=41.1538461538462, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI40806173, Length=313, Percent_Identity=39.6166134185303, Blast_Score=189, Evalue=7e-48,
Organism=Homo sapiens, GI24430151, Length=296, Percent_Identity=37.8378378378378, Blast_Score=189, Evalue=7e-48,
Organism=Homo sapiens, GI24430155, Length=260, Percent_Identity=41.1538461538462, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI157671927, Length=249, Percent_Identity=40.9638554216867, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI45643123, Length=273, Percent_Identity=37.3626373626374, Blast_Score=180, Evalue=4e-45,
Organism=Homo sapiens, GI45643125, Length=273, Percent_Identity=37.3626373626374, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI229577436, Length=265, Percent_Identity=37.3584905660377, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI194018488, Length=246, Percent_Identity=39.0243902439024, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI4505725, Length=236, Percent_Identity=36.864406779661, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI24497618, Length=275, Percent_Identity=34.5454545454545, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI14149767, Length=238, Percent_Identity=38.2352941176471, Blast_Score=147, Evalue=4e-35,
Organism=Homo sapiens, GI62177112, Length=238, Percent_Identity=38.2352941176471, Blast_Score=147, Evalue=4e-35,
Organism=Homo sapiens, GI5901990, Length=291, Percent_Identity=34.020618556701, Blast_Score=144, Evalue=4e-34,
Organism=Homo sapiens, GI17865802, Length=246, Percent_Identity=38.2113821138211, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI153792536, Length=246, Percent_Identity=37.3983739837398, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI11875211, Length=283, Percent_Identity=35.3356890459364, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI40806170, Length=283, Percent_Identity=35.3356890459364, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI226371754, Length=253, Percent_Identity=37.1541501976285, Blast_Score=137, Evalue=5e-32,
Organism=Homo sapiens, GI7019569, Length=248, Percent_Identity=36.2903225806452, Blast_Score=136, Evalue=7e-32,
Organism=Homo sapiens, GI156564401, Length=220, Percent_Identity=36.8181818181818, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI31742536, Length=237, Percent_Identity=33.3333333333333, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI112789543, Length=237, Percent_Identity=33.3333333333333, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI310125280, Length=220, Percent_Identity=36.3636363636364, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI310125282, Length=220, Percent_Identity=36.3636363636364, Blast_Score=130, Evalue=5e-30,
Organism=Homo sapiens, GI31377644, Length=282, Percent_Identity=34.3971631205674, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI64084766, Length=276, Percent_Identity=26.4492753623188, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI116292174, Length=256, Percent_Identity=28.515625, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1789568, Length=648, Percent_Identity=43.9814814814815, Blast_Score=524, Evalue=1e-150,
Organism=Caenorhabditis elegans, GI71994521, Length=454, Percent_Identity=55.9471365638767, Blast_Score=490, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI115534323, Length=476, Percent_Identity=46.4285714285714, Blast_Score=423, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17554264, Length=438, Percent_Identity=45.8904109589041, Blast_Score=377, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17554786, Length=256, Percent_Identity=44.921875, Blast_Score=219, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI25144278, Length=256, Percent_Identity=44.140625, Blast_Score=215, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI25144281, Length=257, Percent_Identity=43.9688715953307, Blast_Score=215, Evalue=7e-56,
Organism=Caenorhabditis elegans, GI17563248, Length=259, Percent_Identity=42.8571428571429, Blast_Score=205, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI17532375, Length=296, Percent_Identity=37.1621621621622, Blast_Score=199, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI17508701, Length=254, Percent_Identity=42.1259842519685, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17563250, Length=296, Percent_Identity=38.5135135135135, Blast_Score=192, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17531535, Length=305, Percent_Identity=36.0655737704918, Blast_Score=187, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI71987364, Length=246, Percent_Identity=39.4308943089431, Blast_Score=187, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI71987372, Length=246, Percent_Identity=39.4308943089431, Blast_Score=187, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17505546, Length=258, Percent_Identity=41.4728682170543, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17508053, Length=254, Percent_Identity=40.1574803149606, Blast_Score=181, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17554784, Length=252, Percent_Identity=42.4603174603175, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17537217, Length=272, Percent_Identity=36.7647058823529, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=46.6666666666667, Blast_Score=155, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=46.6666666666667, Blast_Score=155, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI25153574, Length=232, Percent_Identity=37.0689655172414, Blast_Score=149, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17562804, Length=241, Percent_Identity=35.2697095435685, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI193209502, Length=231, Percent_Identity=36.7965367965368, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI86561515, Length=245, Percent_Identity=35.5102040816327, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI133931034, Length=236, Percent_Identity=36.864406779661, Blast_Score=135, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI193206114, Length=237, Percent_Identity=36.2869198312236, Blast_Score=135, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI193206116, Length=237, Percent_Identity=36.2869198312236, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI25146157, Length=312, Percent_Identity=34.2948717948718, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI133901658, Length=298, Percent_Identity=31.5436241610738, Blast_Score=130, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI133901662, Length=240, Percent_Identity=35, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17560432, Length=264, Percent_Identity=34.469696969697, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI32563584, Length=232, Percent_Identity=35.3448275862069, Blast_Score=112, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17508421, Length=254, Percent_Identity=34.251968503937, Blast_Score=112, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17541226, Length=250, Percent_Identity=32, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17541224, Length=250, Percent_Identity=32, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17570511, Length=97, Percent_Identity=37.1134020618557, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320854, Length=525, Percent_Identity=50.4761904761905, Blast_Score=516, Evalue=1e-147,
Organism=Saccharomyces cerevisiae, GI6323736, Length=513, Percent_Identity=49.5126705653021, Blast_Score=503, Evalue=1e-143,
Organism=Saccharomyces cerevisiae, GI6325281, Length=499, Percent_Identity=42.0841683366733, Blast_Score=389, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6322704, Length=260, Percent_Identity=41.1538461538462, Blast_Score=205, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6321390, Length=246, Percent_Identity=41.0569105691057, Blast_Score=202, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6324691, Length=254, Percent_Identity=42.1259842519685, Blast_Score=201, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6324833, Length=250, Percent_Identity=42.8, Blast_Score=194, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6320077, Length=251, Percent_Identity=41.8326693227092, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6320197, Length=262, Percent_Identity=40.8396946564886, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6320602, Length=250, Percent_Identity=42.4, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6323429, Length=265, Percent_Identity=38.4905660377359, Blast_Score=177, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6324000, Length=240, Percent_Identity=40.4166666666667, Blast_Score=174, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6322994, Length=236, Percent_Identity=39.4067796610169, Blast_Score=165, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322651, Length=247, Percent_Identity=35.2226720647773, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6321709, Length=237, Percent_Identity=38.8185654008439, Blast_Score=153, Evalue=7e-38,
Organism=Saccharomyces cerevisiae, GI6325431, Length=340, Percent_Identity=33.2352941176471, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6319554, Length=237, Percent_Identity=37.1308016877637, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6325183, Length=273, Percent_Identity=32.967032967033, Blast_Score=127, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6321465, Length=312, Percent_Identity=32.3717948717949, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6320887, Length=247, Percent_Identity=34.0080971659919, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320583, Length=157, Percent_Identity=31.2101910828025, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24665814, Length=632, Percent_Identity=45.5696202531646, Blast_Score=510, Evalue=1e-144,
Organism=Drosophila melanogaster, GI28574878, Length=632, Percent_Identity=45.5696202531646, Blast_Score=510, Evalue=1e-144,
Organism=Drosophila melanogaster, GI24639391, Length=474, Percent_Identity=49.3670886075949, Blast_Score=455, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24658770, Length=492, Percent_Identity=43.4959349593496, Blast_Score=384, Evalue=1e-106,
Organism=Drosophila melanogaster, GI45554047, Length=185, Percent_Identity=57.8378378378378, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI19920408, Length=256, Percent_Identity=42.96875, Blast_Score=213, Evalue=5e-55,
Organism=Drosophila melanogaster, GI24651451, Length=256, Percent_Identity=42.578125, Blast_Score=211, Evalue=9e-55,
Organism=Drosophila melanogaster, GI17738151, Length=254, Percent_Identity=43.3070866141732, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI17137738, Length=253, Percent_Identity=42.6877470355731, Blast_Score=201, Evalue=2e-51,
Organism=Drosophila melanogaster, GI161076488, Length=284, Percent_Identity=38.0281690140845, Blast_Score=193, Evalue=4e-49,
Organism=Drosophila melanogaster, GI17137560, Length=284, Percent_Identity=38.0281690140845, Blast_Score=193, Evalue=4e-49,
Organism=Drosophila melanogaster, GI161076486, Length=284, Percent_Identity=38.0281690140845, Blast_Score=193, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24649446, Length=246, Percent_Identity=42.6829268292683, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI18860063, Length=245, Percent_Identity=42.8571428571429, Blast_Score=189, Evalue=7e-48,
Organism=Drosophila melanogaster, GI281361487, Length=245, Percent_Identity=42.0408163265306, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI19921202, Length=261, Percent_Identity=38.6973180076628, Blast_Score=186, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24640100, Length=246, Percent_Identity=39.0243902439024, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24660075, Length=268, Percent_Identity=36.1940298507463, Blast_Score=179, Evalue=6e-45,
Organism=Drosophila melanogaster, GI281365776, Length=268, Percent_Identity=36.1940298507463, Blast_Score=179, Evalue=6e-45,
Organism=Drosophila melanogaster, GI45552965, Length=268, Percent_Identity=36.1940298507463, Blast_Score=178, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24663015, Length=246, Percent_Identity=37.8048780487805, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24656820, Length=257, Percent_Identity=35.0194552529183, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24656825, Length=257, Percent_Identity=35.0194552529183, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24652279, Length=234, Percent_Identity=39.3162393162393, Blast_Score=168, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281363136, Length=268, Percent_Identity=35.8208955223881, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI78707192, Length=268, Percent_Identity=35.8208955223881, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI281360144, Length=273, Percent_Identity=36.6300366300366, Blast_Score=152, Evalue=9e-37,
Organism=Drosophila melanogaster, GI281360140, Length=273, Percent_Identity=36.6300366300366, Blast_Score=152, Evalue=9e-37,
Organism=Drosophila melanogaster, GI281360136, Length=273, Percent_Identity=36.6300366300366, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24644411, Length=273, Percent_Identity=36.6300366300366, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281360142, Length=276, Percent_Identity=36.5942028985507, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI21357333, Length=276, Percent_Identity=36.5942028985507, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI281360146, Length=276, Percent_Identity=36.5942028985507, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI281360138, Length=276, Percent_Identity=36.5942028985507, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI18859657, Length=245, Percent_Identity=37.5510204081633, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI21355121, Length=216, Percent_Identity=37.5, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24644145, Length=238, Percent_Identity=35.7142857142857, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24581396, Length=242, Percent_Identity=36.3636363636364, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI20129529, Length=264, Percent_Identity=34.469696969697, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17864540, Length=215, Percent_Identity=37.2093023255814, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28573010, Length=217, Percent_Identity=35.9447004608295, Blast_Score=126, Evalue=6e-29,
Organism=Drosophila melanogaster, GI20129423, Length=244, Percent_Identity=35.655737704918, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI28571849, Length=263, Percent_Identity=32.6996197718631, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28571847, Length=263, Percent_Identity=32.6996197718631, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24639486, Length=286, Percent_Identity=32.8671328671329, Blast_Score=112, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642 [H]

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 76079; Mature: 75948

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNNLFKPQNPYKNDPENNDKKPKFSLLYYVVIVLLLIGLQLAFFWSGSSEEIPYSEFRS
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHH
YIEENKIESVKIAPERIYVNLKPGVIPSVAKNGDGSLSAEPTEVYVTPVVDDGLIELLES
HHHHCCCCEEEECCEEEEEEECCCCCCHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHH
KGISYQGIPGNTWIGELLQWILPFALLIGIYFFVFRRLGGPGSQFMNISKNKAALYENLD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHCCH
EHTRITFKDVAGLDEAKAEVMEVVGFLKDPKKYTKLGGKLPKGVLLVGPPGTGKTLLAKA
HHCEEEHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCEEEECCCCCCHHHHHHH
VAGEADVPFFSISGSDFVEMFVGVGAARVRDLFREAKEKAPCIIFIDEIDAVGRSRGKGA
HCCCCCCCEEECCCHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEECHHHHHCCCCCCC
MMGANDERENTLNQLLVEMDGFATDKGVILMAATNRPDVLDNALLRPGRFDRQIMVDKPD
CCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCEEEECCCC
LKGRVDTFKVHTKKLSLSPDVNVKVLASQTPGFAGAEIANAANEAALLASRRGKQSIEMK
CCCCCCEEEEEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHH
DFEDAIERVVAGLEKKNKVINPKEKKVVAYHESGHAIISWMMAENDAVQKISIVPRGMSA
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEEHHCCCCHHEEEECCCCHHH
LGYTMNLPLEDRYLMTKHELYSRICGLLGGRIAEEIIFDEISTGAQNDLEKITEIAYNMV
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VVYGMSKKLGNISYYESNNPYYGGPGVDKKYSEHTARLIDEEVHQLIDQAQQQVREILTE
EEEECCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NHDKLEMLAQELLKNEVLHYCKIEEILGRRPGASDDDAMSEECGKKAADRETGPDSNGKT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
PVDEEELKNLEAAVEKIRQSKNAEEN
CCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PNNLFKPQNPYKNDPENNDKKPKFSLLYYVVIVLLLIGLQLAFFWSGSSEEIPYSEFRS
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHH
YIEENKIESVKIAPERIYVNLKPGVIPSVAKNGDGSLSAEPTEVYVTPVVDDGLIELLES
HHHHCCCCEEEECCEEEEEEECCCCCCHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHH
KGISYQGIPGNTWIGELLQWILPFALLIGIYFFVFRRLGGPGSQFMNISKNKAALYENLD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHCCH
EHTRITFKDVAGLDEAKAEVMEVVGFLKDPKKYTKLGGKLPKGVLLVGPPGTGKTLLAKA
HHCEEEHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCEEEECCCCCCHHHHHHH
VAGEADVPFFSISGSDFVEMFVGVGAARVRDLFREAKEKAPCIIFIDEIDAVGRSRGKGA
HCCCCCCCEEECCCHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEECHHHHHCCCCCCC
MMGANDERENTLNQLLVEMDGFATDKGVILMAATNRPDVLDNALLRPGRFDRQIMVDKPD
CCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCEEEECCCC
LKGRVDTFKVHTKKLSLSPDVNVKVLASQTPGFAGAEIANAANEAALLASRRGKQSIEMK
CCCCCCEEEEEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHH
DFEDAIERVVAGLEKKNKVINPKEKKVVAYHESGHAIISWMMAENDAVQKISIVPRGMSA
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEEHHCCCCHHEEEECCCCHHH
LGYTMNLPLEDRYLMTKHELYSRICGLLGGRIAEEIIFDEISTGAQNDLEKITEIAYNMV
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VVYGMSKKLGNISYYESNNPYYGGPGVDKKYSEHTARLIDEEVHQLIDQAQQQVREILTE
EEEECCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NHDKLEMLAQELLKNEVLHYCKIEEILGRRPGASDDDAMSEECGKKAADRETGPDSNGKT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
PVDEEELKNLEAAVEKIRQSKNAEEN
CCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA