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The map label for this gene is mocR [H]

Identifier: 189352617

GI number: 189352617

Start: 701575

End: 703110

Strand: Reverse

Name: mocR [H]

Synonym: BMULJ_03848

Alternate gene names: 189352617

Gene position: 703110-701575 (Counterclockwise)

Preceding gene: 189352623

Following gene: 189352611

Centisome position: 28.43

GC content: 69.08

Gene sequence:

>1536_bases
TTGGATACCGTGATCGTCGCCGACTGGCTGTCCGCCCGTCTCGACCGGACTTCGTCCGAGCCGATGTACCGGCAGTTGCT
GCAACTGATGCAGCAGGTCATCCTGACCGGCGAATTGGGGCCGGGGACGAAGCTGCCGAGTTCGCGCACGCTGGCCGCCG
ACCTGTCGATCGCCCGCAATACGGTGCTGCACGTGTACGACCAGTTGACGGCCGAAGGCTACGTCCTGACGACGACCGGC
AGCGGCACCTATGTCGCCGACACGCGGCCCGACGCCGCCGCGATGCGCGCGCACGGCGCGGGCGCGGCGCGTTCGGACGG
CGGCGCGGCAACGTCCGCGACCGCGGCGGCCGACGCGCAAGGCGGGCTGTCGATGCGCGGCCGGCAGCTGATCGAGCATG
CGGGCGTGTCGCGCCGTCAGTGGGGTGCATTCATGCCGGGGGTGCCGGACGTCTCCGAATTTCCGAGCCGCACGTGGAGC
CGCCTGCAGGCGCGGCTCTGGAAGGAAGCGAACCCCGAACTGCTGACGTACGCGCCGGGCGGCGGCTATCGGCCGCTGCG
TCGCGCGCTCGCCGACTATCTGCGCGTCGCGCGCTCGGTCAAATGCTCGCCGGATCAGGTCATCATCACGACCGGCATTC
ATCAGTCGATTGATCTCGCGGTGCGGCTGCTGTCCGACATCGGCGATCGCGCGTGGGTCGAGGAGCCGTGCTACTGGGGC
GTGCGCAGCGTGCTGCAGGCGGCCGGCCTCACGTTGGCGCCCGTGCCCGTCGATCAGGAAGGGCTCGCGCCGAGCGCGAG
CGACATGCAGCACCCGCCGCGGCTCGTTCTCGTCACGCCGTCGCATCAGTATCCGCTCGGGATGGTGATGAGTCTCGCGC
GGCGGCGCATGCTGCTCGAATACGCGCGGCAGCATCGCTGCTGGATCATCGAGGACGACTACGACAGCGAATTCCGTTAC
GGCAGCCGCCCGCTCGCGTCGCTGCAGGGGCTCGACGACGGCGGCCGCGTCATCTACGTCGGCAGTCTCGGCAAGATGCT
GTTTCCGGGCCTGCGGATGGGCTACATGGTCGTGCCCGAGCATCTCGTCGACACGTTCCGCACCGGCCTCTCGGAGCTGT
ACCGCGAAGGACAGCTGATGCAGCAGGCGGTGCTCGCCGAGTTCATCATGGACGGTCATCTGACCTCGCACGTGAGGCGG
ATGCGCACGCTATACGGCGAGCGCCGTCAACTGCTGATCGACGCGATCCGCGCGCGCTTCGGCGACACGTTGCCGGTGAT
GGGCGACGAAGCCGGCCTGCATCTGGTGCTCGGGCTGCCCGACGCATGCGACGACCGCGCGGTCACGCAGAGCGCATTCG
AAGCGGGTGTGATCGTGCGGCCGCTGACCAGCTATTACAGCTGCGCCGATACCGCGCAACGCGGGCTGCTGCTCGGCTAT
GCGTGCGTCGCGCATGAAGGGATCGGGCCGGCGTTCGACACGCTCGCGGCAATCATCGAGCAGCATCTGCCGCGGCACGC
GACGCGCGCCGCGTGA

Upstream 100 bases:

>100_bases
CCCCTTTGCTGCGCAACGATCTTTATCGAGATGCGAGCCACTATACGGCGCGCACGGTTCTACAATAGGGAACCATTTCA
ATATTCCCAGTAGGACCACT

Downstream 100 bases:

>100_bases
GCCGACAGCCGCGCGTGCGGGCCGTTATTGCGCGGTTCCCGTCGTAGCCGTAGCCGTCGCGGCCGCACCGCGATCGAGCG
ACGCCGCGCGCACCGCTTCG

Product: DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MDTVIVADWLSARLDRTSSEPMYRQLLQLMQQVILTGELGPGTKLPSSRTLAADLSIARNTVLHVYDQLTAEGYVLTTTG
SGTYVADTRPDAAAMRAHGAGAARSDGGAATSATAAADAQGGLSMRGRQLIEHAGVSRRQWGAFMPGVPDVSEFPSRTWS
RLQARLWKEANPELLTYAPGGGYRPLRRALADYLRVARSVKCSPDQVIITTGIHQSIDLAVRLLSDIGDRAWVEEPCYWG
VRSVLQAAGLTLAPVPVDQEGLAPSASDMQHPPRLVLVTPSHQYPLGMVMSLARRRMLLEYARQHRCWIIEDDYDSEFRY
GSRPLASLQGLDDGGRVIYVGSLGKMLFPGLRMGYMVVPEHLVDTFRTGLSELYREGQLMQQAVLAEFIMDGHLTSHVRR
MRTLYGERRQLLIDAIRARFGDTLPVMGDEAGLHLVLGLPDACDDRAVTQSAFEAGVIVRPLTSYYSCADTAQRGLLLGY
ACVAHEGIGPAFDTLAAIIEQHLPRHATRAA

Sequences:

>Translated_511_residues
MDTVIVADWLSARLDRTSSEPMYRQLLQLMQQVILTGELGPGTKLPSSRTLAADLSIARNTVLHVYDQLTAEGYVLTTTG
SGTYVADTRPDAAAMRAHGAGAARSDGGAATSATAAADAQGGLSMRGRQLIEHAGVSRRQWGAFMPGVPDVSEFPSRTWS
RLQARLWKEANPELLTYAPGGGYRPLRRALADYLRVARSVKCSPDQVIITTGIHQSIDLAVRLLSDIGDRAWVEEPCYWG
VRSVLQAAGLTLAPVPVDQEGLAPSASDMQHPPRLVLVTPSHQYPLGMVMSLARRRMLLEYARQHRCWIIEDDYDSEFRY
GSRPLASLQGLDDGGRVIYVGSLGKMLFPGLRMGYMVVPEHLVDTFRTGLSELYREGQLMQQAVLAEFIMDGHLTSHVRR
MRTLYGERRQLLIDAIRARFGDTLPVMGDEAGLHLVLGLPDACDDRAVTQSAFEAGVIVRPLTSYYSCADTAQRGLLLGY
ACVAHEGIGPAFDTLAAIIEQHLPRHATRAA
>Mature_511_residues
MDTVIVADWLSARLDRTSSEPMYRQLLQLMQQVILTGELGPGTKLPSSRTLAADLSIARNTVLHVYDQLTAEGYVLTTTG
SGTYVADTRPDAAAMRAHGAGAARSDGGAATSATAAADAQGGLSMRGRQLIEHAGVSRRQWGAFMPGVPDVSEFPSRTWS
RLQARLWKEANPELLTYAPGGGYRPLRRALADYLRVARSVKCSPDQVIITTGIHQSIDLAVRLLSDIGDRAWVEEPCYWG
VRSVLQAAGLTLAPVPVDQEGLAPSASDMQHPPRLVLVTPSHQYPLGMVMSLARRRMLLEYARQHRCWIIEDDYDSEFRY
GSRPLASLQGLDDGGRVIYVGSLGKMLFPGLRMGYMVVPEHLVDTFRTGLSELYREGQLMQQAVLAEFIMDGHLTSHVRR
MRTLYGERRQLLIDAIRARFGDTLPVMGDEAGLHLVLGLPDACDDRAVTQSAFEAGVIVRPLTSYYSCADTAQRGLLLGY
ACVAHEGIGPAFDTLAAIIEQHLPRHATRAA

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=392, Percent_Identity=23.469387755102, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI33469970, Length=392, Percent_Identity=23.469387755102, Blast_Score=100, Evalue=5e-21,
Organism=Escherichia coli, GI1787710, Length=486, Percent_Identity=24.8971193415638, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790797, Length=428, Percent_Identity=27.5700934579439, Blast_Score=130, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6321236, Length=364, Percent_Identity=23.6263736263736, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 55908; Mature: 55908

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTVIVADWLSARLDRTSSEPMYRQLLQLMQQVILTGELGPGTKLPSSRTLAADLSIARN
CCCEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
TVLHVYDQLTAEGYVLTTTGSGTYVADTRPDAAAMRAHGAGAARSDGGAATSATAAADAQ
HHHHHHHHHCCCCEEEEECCCCCEEECCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHCCC
GGLSMRGRQLIEHAGVSRRQWGAFMPGVPDVSEFPSRTWSRLQARLWKEANPELLTYAPG
CCCHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
GGYRPLRRALADYLRVARSVKCSPDQVIITTGIHQSIDLAVRLLSDIGDRAWVEEPCYWG
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHHCCCHHHH
VRSVLQAAGLTLAPVPVDQEGLAPSASDMQHPPRLVLVTPSHQYPLGMVMSLARRRMLLE
HHHHHHHCCCEEECCCCCCCCCCCCCHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
YARQHRCWIIEDDYDSEFRYGSRPLASLQGLDDGGRVIYVGSLGKMLFPGLRMGYMVVPE
HHHHCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCEEEEECCHHHHCCHHHCCHHHCCH
HLVDTFRTGLSELYREGQLMQQAVLAEFIMDGHLTSHVRRMRTLYGERRQLLIDAIRARF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDTLPVMGDEAGLHLVLGLPDACDDRAVTQSAFEAGVIVRPLTSYYSCADTAQRGLLLGY
CCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHH
ACVAHEGIGPAFDTLAAIIEQHLPRHATRAA
HHHHHCCCCHHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MDTVIVADWLSARLDRTSSEPMYRQLLQLMQQVILTGELGPGTKLPSSRTLAADLSIARN
CCCEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
TVLHVYDQLTAEGYVLTTTGSGTYVADTRPDAAAMRAHGAGAARSDGGAATSATAAADAQ
HHHHHHHHHCCCCEEEEECCCCCEEECCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHCCC
GGLSMRGRQLIEHAGVSRRQWGAFMPGVPDVSEFPSRTWSRLQARLWKEANPELLTYAPG
CCCHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
GGYRPLRRALADYLRVARSVKCSPDQVIITTGIHQSIDLAVRLLSDIGDRAWVEEPCYWG
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHHCCCHHHH
VRSVLQAAGLTLAPVPVDQEGLAPSASDMQHPPRLVLVTPSHQYPLGMVMSLARRRMLLE
HHHHHHHCCCEEECCCCCCCCCCCCCHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
YARQHRCWIIEDDYDSEFRYGSRPLASLQGLDDGGRVIYVGSLGKMLFPGLRMGYMVVPE
HHHHCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCEEEEECCHHHHCCHHHCCHHHCCH
HLVDTFRTGLSELYREGQLMQQAVLAEFIMDGHLTSHVRRMRTLYGERRQLLIDAIRARF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDTLPVMGDEAGLHLVLGLPDACDDRAVTQSAFEAGVIVRPLTSYYSCADTAQRGLLLGY
CCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHH
ACVAHEGIGPAFDTLAAIIEQHLPRHATRAA
HHHHHCCCCHHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]