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The map label for this gene is cheA [H]

Identifier: 189352353

GI number: 189352353

Start: 405138

End: 407438

Strand: Direct

Name: cheA [H]

Synonym: BMULJ_03572

Alternate gene names: 189352353

Gene position: 405138-407438 (Clockwise)

Preceding gene: 189352352

Following gene: 189352354

Centisome position: 16.38

GC content: 71.32

Gene sequence:

>2301_bases
ATGAGCAACGACGACGATCTGAGCCACCTGTCGCTGCTCGAACTCTATCGCGAGGAAACGCGCACGCAGACGCAGGCGCT
GTCCGAACGCCTGCTCGCGCTCGAAGCCGGCGAACCCGACGCGGCCGCACTCGAGGCCTGCATGCGCGCCGCGCATTCGC
TGAAGGGCGCCGCGCGTATCGTCGGCGTGCCGCTCGGCGTCGACATCGCGGGACGGATGGAAGAGTGCTTCGTCGCCGCG
CAGGCCGGCACGATCGCGCTGAGCGCCGCGCACGTCGACGTGCTGCTGGCCGGCGTCGATTTGCTCGTGCGCGTCGGCGA
TCCGCACGCGGCGCCCGTGTCGCCCGCCGAGATCGACGCGTTCGCGGCAGCACTGACCGGCGCCGACGGCGCGCACACGA
TGCGGATGCCCGCCGCGGCGCCGACGCCGCCCGTCGTCGCGTCGCGCGAGCACGACGCGGCCGCGAACGAGCCGGCCGGC
GTATCGATCGCGGCGCCGTCGCCGGGCGCGCCGCATGCGGCGGCCGAGCCCGCTCAGGCGAACCGCACGGCCGGCGCCGG
CGCGATGCGCCGCGTGCGCGCCGATACGCTGAACCGGCTGCTGAGCCTGTCCGGCGAGTCGCTCGTCGAATCGCGCTGGC
TCAAGCCGTTCGCCGAGTCGATGCTGCGCGTGAAGCGTGCGCAGCGCGATGCCGCGCGCGCGTTGGACCTCGTGTACGAA
CAGTTCGCGGACGAGCTCGACGCGGGCGTGCTCGCATCGATGAACGAAGTTCGGCACATGCTGAACGATCTGCAGCGTTC
GTTCGCCGAGCGGATGGACGAGTTCGACCGCTTCGAGCGGCGCAGCACGCACATCGCGGAGCAACTGTACGACGAGGCGC
TGCAGTGCCGGATGCGGCCGTTCGGCGACGCGACGCGCGCGTATCCGCGCATCGTCCGCGATCTCGCACGCTCGCTCGGC
AAGCAGGTGCGGTTCTCGATCGTCGGCGAAGCCACGCAGGTCGACCGCGACATCCTCGACCTGCTCGACGCGCCGCTCGG
CCATCTGCTGCGCAATGCGATCGACCACGGCGTCGAGTCGCCCGAGGCGCGACGCGCGCGCGGCAAGCCGGCCGAGGCGA
GCGTCACGCTCGAGGCGCGTCATAGCGCGGGGTCGCTGCTCGTCAGCGTGATCGACGACGGCCCCGGCGTCGACATGGAC
GCGCTGCGCGCGGCCATCGTGCGCCAGCACCTGACCGACGACGAGACGGCCGCGCGGCTCTCCGACCCCGAGCTGCTCGA
GTTTCTGCTGCTGCCCGGCTTTTCGATGCGCGACGCGGTGACCGATGTGTCGGGCCGCGGCGTCGGCCTCGACGCCGTGC
AGGAAATGGTGCGCAGCGTGCGCGGCGCGGTGCGCATCTTCAACGAGCCGGGCGCGGGCATGCGCTTCGTGCTGCAGCTG
CCGCTCACGCTGTCGGTGATCCGCAGCCTGCTGGTCGACGTCGGCGGCGAACCGTACGCGTTCCCGCTCGCGCACGTGCG
CCGCACGCTCGAACTCGCGCACGAGGACATCGACGTGCTCGAAGGGCAGCCGCATTTCCCGTTCGACGGCCGGCGCGCGG
GGCTCGTCGCCGCGCATCAGCTGCTCGATGCGGGCGAGCCGGACGCGTCGCGCGCGAGCACGGCGGTCGTCGTGGTCGGC
GGCGAGCCGGAGCTGTACGGCGTCGCGGTCGACCGCTTCCTCGGCGAGCGCATGCTGGTCGTGCAGCCGCTCGACAGCCG
CCTGCACAAGATCCAGAACATCGCGGCCGGCGCGCTGCTCGAGAACGGCGATCCGGTGCTGATCGTCGACGTCGAGGATC
TGATTCGCTCGGTCGACAAGCTCGTGCGCGGCGGTCAGCTCGCCAAGCTCACGCGCGATCCGCAGCTCGCGCACGCGGAT
CGCCGCCGCCGCGTGCTGGTCGTCGACGATTCGCTGACCGTGCGCGAACTCGAGCGCAAGCTGCTCGAGAAGCGCGGCTA
CGACGTGACCGTCGCCGTCGACGGCATGGACGGCTGGAACGCGGTGCGCGGCGAAGCGTTCGATCTCGTCGTGACCGACG
TCGACATGCCGCGGATGGACGGCATCGAGCTCGTCACGCTGATCAAGAACGATCCGCTGCTGCAGCGCGTGCCCGTCATG
ATCGTGTCGTACAAGGATCGCGACGAGGATCGCCGTCGCGGGCTCGACGCCGGCGCCGACTACTACCTCGCGAAGAGCAG
CTTCCACGACGAGGCGCTGCTCGACGCGGTGCACGACCTGATCGGGGATGCGCGCGGATGA

Upstream 100 bases:

>100_bases
CGAGCGCGGGCCTGTCGCGCGGCGTGCTGTCGTGGCGCGGCAAGTCCGTCGGCCTGCTCGACGACGATCGGCTGTTCGAC
GCCGTCACGCGGAGCATGCG

Downstream 100 bases:

>100_bases
ACATCGGCATCGTCAACGATCTGCCGCTCGCGGTCGAGGCACTGCGCCGCGTGCTCGCGCAGCGGCCCGATCATCGCGTG
CTGTGGGTCGCGTCGGACGG

Product: two-component system sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 766; Mature: 765

Protein sequence:

>766_residues
MSNDDDLSHLSLLELYREETRTQTQALSERLLALEAGEPDAAALEACMRAAHSLKGAARIVGVPLGVDIAGRMEECFVAA
QAGTIALSAAHVDVLLAGVDLLVRVGDPHAAPVSPAEIDAFAAALTGADGAHTMRMPAAAPTPPVVASREHDAAANEPAG
VSIAAPSPGAPHAAAEPAQANRTAGAGAMRRVRADTLNRLLSLSGESLVESRWLKPFAESMLRVKRAQRDAARALDLVYE
QFADELDAGVLASMNEVRHMLNDLQRSFAERMDEFDRFERRSTHIAEQLYDEALQCRMRPFGDATRAYPRIVRDLARSLG
KQVRFSIVGEATQVDRDILDLLDAPLGHLLRNAIDHGVESPEARRARGKPAEASVTLEARHSAGSLLVSVIDDGPGVDMD
ALRAAIVRQHLTDDETAARLSDPELLEFLLLPGFSMRDAVTDVSGRGVGLDAVQEMVRSVRGAVRIFNEPGAGMRFVLQL
PLTLSVIRSLLVDVGGEPYAFPLAHVRRTLELAHEDIDVLEGQPHFPFDGRRAGLVAAHQLLDAGEPDASRASTAVVVVG
GEPELYGVAVDRFLGERMLVVQPLDSRLHKIQNIAAGALLENGDPVLIVDVEDLIRSVDKLVRGGQLAKLTRDPQLAHAD
RRRRVLVVDDSLTVRELERKLLEKRGYDVTVAVDGMDGWNAVRGEAFDLVVTDVDMPRMDGIELVTLIKNDPLLQRVPVM
IVSYKDRDEDRRRGLDAGADYYLAKSSFHDEALLDAVHDLIGDARG

Sequences:

>Translated_766_residues
MSNDDDLSHLSLLELYREETRTQTQALSERLLALEAGEPDAAALEACMRAAHSLKGAARIVGVPLGVDIAGRMEECFVAA
QAGTIALSAAHVDVLLAGVDLLVRVGDPHAAPVSPAEIDAFAAALTGADGAHTMRMPAAAPTPPVVASREHDAAANEPAG
VSIAAPSPGAPHAAAEPAQANRTAGAGAMRRVRADTLNRLLSLSGESLVESRWLKPFAESMLRVKRAQRDAARALDLVYE
QFADELDAGVLASMNEVRHMLNDLQRSFAERMDEFDRFERRSTHIAEQLYDEALQCRMRPFGDATRAYPRIVRDLARSLG
KQVRFSIVGEATQVDRDILDLLDAPLGHLLRNAIDHGVESPEARRARGKPAEASVTLEARHSAGSLLVSVIDDGPGVDMD
ALRAAIVRQHLTDDETAARLSDPELLEFLLLPGFSMRDAVTDVSGRGVGLDAVQEMVRSVRGAVRIFNEPGAGMRFVLQL
PLTLSVIRSLLVDVGGEPYAFPLAHVRRTLELAHEDIDVLEGQPHFPFDGRRAGLVAAHQLLDAGEPDASRASTAVVVVG
GEPELYGVAVDRFLGERMLVVQPLDSRLHKIQNIAAGALLENGDPVLIVDVEDLIRSVDKLVRGGQLAKLTRDPQLAHAD
RRRRVLVVDDSLTVRELERKLLEKRGYDVTVAVDGMDGWNAVRGEAFDLVVTDVDMPRMDGIELVTLIKNDPLLQRVPVM
IVSYKDRDEDRRRGLDAGADYYLAKSSFHDEALLDAVHDLIGDARG
>Mature_765_residues
SNDDDLSHLSLLELYREETRTQTQALSERLLALEAGEPDAAALEACMRAAHSLKGAARIVGVPLGVDIAGRMEECFVAAQ
AGTIALSAAHVDVLLAGVDLLVRVGDPHAAPVSPAEIDAFAAALTGADGAHTMRMPAAAPTPPVVASREHDAAANEPAGV
SIAAPSPGAPHAAAEPAQANRTAGAGAMRRVRADTLNRLLSLSGESLVESRWLKPFAESMLRVKRAQRDAARALDLVYEQ
FADELDAGVLASMNEVRHMLNDLQRSFAERMDEFDRFERRSTHIAEQLYDEALQCRMRPFGDATRAYPRIVRDLARSLGK
QVRFSIVGEATQVDRDILDLLDAPLGHLLRNAIDHGVESPEARRARGKPAEASVTLEARHSAGSLLVSVIDDGPGVDMDA
LRAAIVRQHLTDDETAARLSDPELLEFLLLPGFSMRDAVTDVSGRGVGLDAVQEMVRSVRGAVRIFNEPGAGMRFVLQLP
LTLSVIRSLLVDVGGEPYAFPLAHVRRTLELAHEDIDVLEGQPHFPFDGRRAGLVAAHQLLDAGEPDASRASTAVVVVGG
EPELYGVAVDRFLGERMLVVQPLDSRLHKIQNIAAGALLENGDPVLIVDVEDLIRSVDKLVRGGQLAKLTRDPQLAHADR
RRRVLVVDDSLTVRELERKLLEKRGYDVTVAVDGMDGWNAVRGEAFDLVVTDVDMPRMDGIELVTLIKNDPLLQRVPVMI
VSYKDRDEDRRRGLDAGADYYLAKSSFHDEALLDAVHDLIGDARG

Specific function: FrzE is involved in a sensory transduction pathway that controls the frequency at which cells reverse their gliding direction. FrzE seems to be capable of autophosphorylating itself on an histidine residue and then to transfer that group to an aspartate r

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=473, Percent_Identity=30.0211416490486, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1788191, Length=108, Percent_Identity=36.1111111111111, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786599, Length=103, Percent_Identity=33.0097087378641, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR005467
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01584 CheW; PF02518 HATPase_c; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 83023; Mature: 82892

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDDDLSHLSLLELYREETRTQTQALSERLLALEAGEPDAAALEACMRAAHSLKGAARI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHE
VGVPLGVDIAGRMEECFVAAQAGTIALSAAHVDVLLAGVDLLVRVGDPHAAPVSPAEIDA
EECCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHH
FAAALTGADGAHTMRMPAAAPTPPVVASREHDAAANEPAGVSIAAPSPGAPHAAAEPAQA
HHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCC
NRTAGAGAMRRVRADTLNRLLSLSGESLVESRWLKPFAESMLRVKRAQRDAARALDLVYE
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFADELDAGVLASMNEVRHMLNDLQRSFAERMDEFDRFERRSTHIAEQLYDEALQCRMRP
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FGDATRAYPRIVRDLARSLGKQVRFSIVGEATQVDRDILDLLDAPLGHLLRNAIDHGVES
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
PEARRARGKPAEASVTLEARHSAGSLLVSVIDDGPGVDMDALRAAIVRQHLTDDETAARL
CHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHC
SDPELLEFLLLPGFSMRDAVTDVSGRGVGLDAVQEMVRSVRGAVRIFNEPGAGMRFVLQL
CCHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCEEEEEEC
PLTLSVIRSLLVDVGGEPYAFPLAHVRRTLELAHEDIDVLEGQPHFPFDGRRAGLVAAHQ
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LLDAGEPDASRASTAVVVVGGEPELYGVAVDRFLGERMLVVQPLDSRLHKIQNIAAGALL
HHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHEE
ENGDPVLIVDVEDLIRSVDKLVRGGQLAKLTRDPQLAHADRRRRVLVVDDSLTVRELERK
ECCCCEEEEEHHHHHHHHHHHHCCCCEEECCCCCCHHHHHCCCEEEEECCCCHHHHHHHH
LLEKRGYDVTVAVDGMDGWNAVRGEAFDLVVTDVDMPRMDGIELVTLIKNDPLLQRVPVM
HHHHCCCEEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEECCCCHHHHCCEE
IVSYKDRDEDRRRGLDAGADYYLAKSSFHDEALLDAVHDLIGDARG
EEEECCCCHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SNDDDLSHLSLLELYREETRTQTQALSERLLALEAGEPDAAALEACMRAAHSLKGAARI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHE
VGVPLGVDIAGRMEECFVAAQAGTIALSAAHVDVLLAGVDLLVRVGDPHAAPVSPAEIDA
EECCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHH
FAAALTGADGAHTMRMPAAAPTPPVVASREHDAAANEPAGVSIAAPSPGAPHAAAEPAQA
HHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCC
NRTAGAGAMRRVRADTLNRLLSLSGESLVESRWLKPFAESMLRVKRAQRDAARALDLVYE
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFADELDAGVLASMNEVRHMLNDLQRSFAERMDEFDRFERRSTHIAEQLYDEALQCRMRP
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FGDATRAYPRIVRDLARSLGKQVRFSIVGEATQVDRDILDLLDAPLGHLLRNAIDHGVES
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
PEARRARGKPAEASVTLEARHSAGSLLVSVIDDGPGVDMDALRAAIVRQHLTDDETAARL
CHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHC
SDPELLEFLLLPGFSMRDAVTDVSGRGVGLDAVQEMVRSVRGAVRIFNEPGAGMRFVLQL
CCHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCEEEEEEC
PLTLSVIRSLLVDVGGEPYAFPLAHVRRTLELAHEDIDVLEGQPHFPFDGRRAGLVAAHQ
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LLDAGEPDASRASTAVVVVGGEPELYGVAVDRFLGERMLVVQPLDSRLHKIQNIAAGALL
HHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHEE
ENGDPVLIVDVEDLIRSVDKLVRGGQLAKLTRDPQLAHADRRRRVLVVDDSLTVRELERK
ECCCCEEEEEHHHHHHHHHHHHCCCCEEECCCCCCHHHHHCCCEEEEECCCCHHHHHHHH
LLEKRGYDVTVAVDGMDGWNAVRGEAFDLVVTDVDMPRMDGIELVTLIKNDPLLQRVPVM
HHHHCCCEEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEECCCCHHHHCCEE
IVSYKDRDEDRRRGLDAGADYYLAKSSFHDEALLDAVHDLIGDARG
EEEECCCCHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2165608; 2123853 [H]