Click here to switch to the map view.

The map label for this gene is tlpB [H]

Identifier: 189352349

GI number: 189352349

Start: 400730

End: 402406

Strand: Direct

Name: tlpB [H]

Synonym: BMULJ_03568

Alternate gene names: 189352349

Gene position: 400730-402406 (Clockwise)

Preceding gene: 189352348

Following gene: 189352350

Centisome position: 16.2

GC content: 67.86

Gene sequence:

>1677_bases
ATGGCCACCGTGACGCCCCGCGCGACCAATGAAAGCCTGCCCCCGACGATCGGCGCCGTGCGGCTGACGCTCGGCAACCG
CATCCTGCTCAGCTTCGGCGTGCTGTTCGTGCTGATGCTCGTGACCGCCGGCGTGTCTTACGAGCGCTTGCGCGCGATCA
ACACGGAAGCCGTCAGCATCGAGCGCGACTCGCTGCCCGGCGTCTATCTGGCGGCGTCGCTGCGCGGCTCCGTCAACGAG
ACGTTCATGGCGCTGCAGCAGGCGACCTTCGTCGATACGGACAGCGAAGCCGTGCATCGCGATCTCGCGCGCGTCGCCGA
CGCGACGAAGGAGATCGACACGCTGTCGGCCGACTATCAGGCCACGACGTTCCGCGACGACGATCGCGCGCGCTTCGCGA
CGTTCCGCGCCGCGTACGACCGCTATTTGCCGCTGCTCAACGACGCCGCGCAGAAAAGCCGGCTGTCGCGCGACGATGCG
GTCGCCGCGTACGCGAAGGTGCTGCCGGCATGGACGGAGACGGTCCGCTACGCCAATACGCTCGTGCAGGAGAACCGCAA
GTTCGCGGACGAATCGGCGAAGCAGATCCGCAATTCGGTGCAGGACACCGAGATCGTGCTCGCGGCCGCGCTCGGGATCG
TACTGCTGTCCGCGCTCGCGCTCGGCTACGGCCTGTACCGGACGATCACCGTGCCGATGGCGCGGCTCGTCGAGGTGCAC
GACGTGATGCGCACCGGCAATCTGACGCAGCGCCTGAACCTGAGGCGCCGCGACGAGTTCGGCACGCTCGAGACCGGTTT
CAACCGGATGGCGGACGAACTGACGGAACTCGTCGCGCGCGCGCAGCAGTCGTCGCTGCAGGTGACGACGTCGGTGGCCG
AGATCGCCGCGACGTCGCGCGAGCAGCAGGCGACCGCGAACGAGACGGCGGCGACCACGACCGAGATCGGCGCGACCTCG
CGCGAGATCTTCGCGACGTCGCGCGATCTGTTGCGCACGATGAACGAAGTGGCCGGCGTCGCCGAGCAGTCGGCGACGCT
CGCGGGCGTGAGCCAGAGCGGGCTCACGCGGATGGGCGAGACGATGCGCAGCGTGATGGACGCGGCCGGCTCGGTGAACG
CGAAGCTCGCGATCCTCAACGAGAAGGCGCTCAATATCAACCAGGTCGTCGCGACGATCACCAAGGTTGCCGATCAGACG
AACCTGCTGTCGCTGAACGCGGCGATCGAAGCGGAGAAGGCCGGCGAATACGGGCGCGGCTTCGCGGTCGTCGCGACCGA
GATCCGGCGCCTGGCCGACCAGACCGCAGTCGCGACCTACGACATCGAGCAGACGGTGAAGGAAATCCAGTCGGCGGTGT
CGGCCGGCGTGATGGGGATGGACAAGTTCTCCGAAGAAGTGCGGCGCGGGATGCTCGACGTGCAGCAGGTCGGCGGACAG
CTGTCGCAGATCATCGCCGAAGTGCAGACGCTCGCGCCGCGCTTCCAGATGGTCAACGAAGGCATGCAGACGCAGGCGAA
CGGCGCCGAGCAGATCACGCAGGCGCTGTCGCAGCTGTCGGAGGCCGCGCAGCAGACGGCCGAGTCGCTGCGGCAGTCGT
CGCAGGCGATCGACGACCTGACGCTCGTCGCGAACCAGCTGCGCACGAGCGTGTCGCGCTTCAAGGTCGACGCGTGA

Upstream 100 bases:

>100_bases
CCGAGGCCGTGCCGACCCCGATGCGTTCCCGGCGTGCCCAGCGGCGCGCCGGCGAGCGCGGATTTTTTTCAACGCAGTTA
TCAGAAAGCCCATAACCAAC

Downstream 100 bases:

>100_bases
CGCGCGCGGAATCGCAGAACGGCGCGCACGCGCTGTTCCTGATGTTCGAGCTCGACGGCGAACGCTACGCGCTCGACGCG
GCCGGCATCGACGCGGTGCT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MATVTPRATNESLPPTIGAVRLTLGNRILLSFGVLFVLMLVTAGVSYERLRAINTEAVSIERDSLPGVYLAASLRGSVNE
TFMALQQATFVDTDSEAVHRDLARVADATKEIDTLSADYQATTFRDDDRARFATFRAAYDRYLPLLNDAAQKSRLSRDDA
VAAYAKVLPAWTETVRYANTLVQENRKFADESAKQIRNSVQDTEIVLAAALGIVLLSALALGYGLYRTITVPMARLVEVH
DVMRTGNLTQRLNLRRRDEFGTLETGFNRMADELTELVARAQQSSLQVTTSVAEIAATSREQQATANETAATTTEIGATS
REIFATSRDLLRTMNEVAGVAEQSATLAGVSQSGLTRMGETMRSVMDAAGSVNAKLAILNEKALNINQVVATITKVADQT
NLLSLNAAIEAEKAGEYGRGFAVVATEIRRLADQTAVATYDIEQTVKEIQSAVSAGVMGMDKFSEEVRRGMLDVQQVGGQ
LSQIIAEVQTLAPRFQMVNEGMQTQANGAEQITQALSQLSEAAQQTAESLRQSSQAIDDLTLVANQLRTSVSRFKVDA

Sequences:

>Translated_558_residues
MATVTPRATNESLPPTIGAVRLTLGNRILLSFGVLFVLMLVTAGVSYERLRAINTEAVSIERDSLPGVYLAASLRGSVNE
TFMALQQATFVDTDSEAVHRDLARVADATKEIDTLSADYQATTFRDDDRARFATFRAAYDRYLPLLNDAAQKSRLSRDDA
VAAYAKVLPAWTETVRYANTLVQENRKFADESAKQIRNSVQDTEIVLAAALGIVLLSALALGYGLYRTITVPMARLVEVH
DVMRTGNLTQRLNLRRRDEFGTLETGFNRMADELTELVARAQQSSLQVTTSVAEIAATSREQQATANETAATTTEIGATS
REIFATSRDLLRTMNEVAGVAEQSATLAGVSQSGLTRMGETMRSVMDAAGSVNAKLAILNEKALNINQVVATITKVADQT
NLLSLNAAIEAEKAGEYGRGFAVVATEIRRLADQTAVATYDIEQTVKEIQSAVSAGVMGMDKFSEEVRRGMLDVQQVGGQ
LSQIIAEVQTLAPRFQMVNEGMQTQANGAEQITQALSQLSEAAQQTAESLRQSSQAIDDLTLVANQLRTSVSRFKVDA
>Mature_557_residues
ATVTPRATNESLPPTIGAVRLTLGNRILLSFGVLFVLMLVTAGVSYERLRAINTEAVSIERDSLPGVYLAASLRGSVNET
FMALQQATFVDTDSEAVHRDLARVADATKEIDTLSADYQATTFRDDDRARFATFRAAYDRYLPLLNDAAQKSRLSRDDAV
AAYAKVLPAWTETVRYANTLVQENRKFADESAKQIRNSVQDTEIVLAAALGIVLLSALALGYGLYRTITVPMARLVEVHD
VMRTGNLTQRLNLRRRDEFGTLETGFNRMADELTELVARAQQSSLQVTTSVAEIAATSREQQATANETAATTTEIGATSR
EIFATSRDLLRTMNEVAGVAEQSATLAGVSQSGLTRMGETMRSVMDAAGSVNAKLAILNEKALNINQVVATITKVADQTN
LLSLNAAIEAEKAGEYGRGFAVVATEIRRLADQTAVATYDIEQTVKEIQSAVSAGVMGMDKFSEEVRRGMLDVQQVGGQL
SQIIAEVQTLAPRFQMVNEGMQTQANGAEQITQALSQLSEAAQQTAESLRQSSQAIDDLTLVANQLRTSVSRFKVDA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=343, Percent_Identity=29.7376093294461, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788194, Length=353, Percent_Identity=26.9121813031161, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1787690, Length=333, Percent_Identity=27.027027027027, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI2367378, Length=345, Percent_Identity=24.6376811594203, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1789453, Length=233, Percent_Identity=28.3261802575107, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 60481; Mature: 60350

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVTPRATNESLPPTIGAVRLTLGNRILLSFGVLFVLMLVTAGVSYERLRAINTEAVSI
CCCCCCCCCCCCCCCCHHHEEHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHEEE
ERDSLPGVYLAASLRGSVNETFMALQQATFVDTDSEAVHRDLARVADATKEIDTLSADYQ
ECCCCCCEEEHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
ATTFRDDDRARFATFRAAYDRYLPLLNDAAQKSRLSRDDAVAAYAKVLPAWTETVRYANT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LVQENRKFADESAKQIRNSVQDTEIVLAAALGIVLLSALALGYGLYRTITVPMARLVEVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVMRTGNLTQRLNLRRRDEFGTLETGFNRMADELTELVARAQQSSLQVTTSVAEIAATSR
HHHHHCCHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQQATANETAATTTEIGATSREIFATSRDLLRTMNEVAGVAEQSATLAGVSQSGLTRMGE
HHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TMRSVMDAAGSVNAKLAILNEKALNINQVVATITKVADQTNLLSLNAAIEAEKAGEYGRG
HHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCC
FAVVATEIRRLADQTAVATYDIEQTVKEIQSAVSAGVMGMDKFSEEVRRGMLDVQQVGGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LSQIIAEVQTLAPRFQMVNEGMQTQANGAEQITQALSQLSEAAQQTAESLRQSSQAIDDL
HHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLVANQLRTSVSRFKVDA
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ATVTPRATNESLPPTIGAVRLTLGNRILLSFGVLFVLMLVTAGVSYERLRAINTEAVSI
CCCCCCCCCCCCCCCHHHEEHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHEEE
ERDSLPGVYLAASLRGSVNETFMALQQATFVDTDSEAVHRDLARVADATKEIDTLSADYQ
ECCCCCCEEEHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
ATTFRDDDRARFATFRAAYDRYLPLLNDAAQKSRLSRDDAVAAYAKVLPAWTETVRYANT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LVQENRKFADESAKQIRNSVQDTEIVLAAALGIVLLSALALGYGLYRTITVPMARLVEVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVMRTGNLTQRLNLRRRDEFGTLETGFNRMADELTELVARAQQSSLQVTTSVAEIAATSR
HHHHHCCHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQQATANETAATTTEIGATSREIFATSRDLLRTMNEVAGVAEQSATLAGVSQSGLTRMGE
HHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TMRSVMDAAGSVNAKLAILNEKALNINQVVATITKVADQTNLLSLNAAIEAEKAGEYGRG
HHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCC
FAVVATEIRRLADQTAVATYDIEQTVKEIQSAVSAGVMGMDKFSEEVRRGMLDVQQVGGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LSQIIAEVQTLAPRFQMVNEGMQTQANGAEQITQALSQLSEAAQQTAESLRQSSQAIDDL
HHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLVANQLRTSVSRFKVDA
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]