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The map label for this gene is gmr [H]

Identifier: 189352176

GI number: 189352176

Start: 212457

End: 214460

Strand: Direct

Name: gmr [H]

Synonym: BMULJ_03394

Alternate gene names: 189352176

Gene position: 212457-214460 (Clockwise)

Preceding gene: 189352175

Following gene: 189352178

Centisome position: 8.59

GC content: 65.67

Gene sequence:

>2004_bases
ATGGATGACGAAAACGATAGCGCAGTGCTCGAGGCGCATGTCGGAACGCGCAGCCCGTGCTGGCGGCTCGGCAGCGACAG
CAATGCACTCGAACTCGCCGCCGTGCGCGGGATGACCAACGTCAGCGTCGCGCTCACCGGCGAGCAGGCCGCGCGCATTC
GTGCGCTCACCGGCGTCACGTCGCACCTCGTGCTCGACATCGTGCTGTTCGGCGAGCGCGTGCCGCTTCACCTCGTCGGC
AGGAAGGTCAATACGACCGACTGGGCCGGCACCGCCTCCGCGTACTCCGATACCGTCTCGGTCGCCAGCGATCTCGCGCA
CGGGCTCGCGTTCGCCGAGCAGGTCGTGTCCGAGGTGAATTCGCTCGTCGTGATCCTCGATCGCAACGGGATGGTGCAGC
GCTTCAACCGGCTCTGCGAGGAAGTGACGGGCAAGCGCGAGGTCGACGTGATCGGCCGCAGCGCGTTCGAGCTGTTCATG
AGCCCCGAGCAGGGCGCGCAGTCGCGCAGCAACATCACGGGCTTTTTTGCGAGCAATCGCGCGTTCTCGGTCGAGCGCTA
CATCAACACCGTGAACGGGCCGCGGCTGTTCCAGTTCCGCAACAAGTTCGTGCAGAGCGGCAGCGGCGCGGAGGAGCAGT
ATCTGATCTGCTCCGGCATCGACATCACCGAGGAGCGCAACGCGCAGCAGCGGCTTACCGAGCTCGCGAACACCGACGTG
CTGACGGGGCTGCCGAACCGCCATGCGATCAGCGAGCGCATCCGCACGGTGATCGCCCAGCAGACCGGCGACACGCCGGG
CCAGGTCGGCATCCTGTTCCTCGATCTCGACAACTTCAAGCGCGTCAACGATCACTACGGCCATATCACCGGCGACCGGC
TGCTGCAGGACGTCTCGGCGATCATCAGCGGCTGCCTGCCGTCCGGCGCCACGCTCGCGCGGCTCGGCGGCGACGAATTC
CTCGTGCTGTTCGAGCAGGGCACGCGCGCGCTGCTCGAAGCGACCGCGCAAATCATTCTCGAACGCCTGCGCACGCCGAT
CCATCTCGGGCTGATGGAGGTCTACACGAGCTGTTCGATCGGCATCGCGATGCATCCGCAGCACGGCGATTCGCTCGAAA
CGCTGATTCGCAACGCCGATACGGCGATGTATGTCGCGAAGGAAGCGGGCAAGCATACGTATCGCGTGTTCTCGCTCGAG
ATGAACCAGCGCGTCGCGAAGTACATGTGGCTCGACACGAACCTGCGCAAGGCGCTCGAGGAAGAACAGTTCGTGCTGCA
TTACCAGCCGGTCGTCGATATCGCGACCGGCGACGTGCATGCCGTCGAAGCGCTGATCCGCTGGCAGTCGCCCGATCGCG
GGCTCGTCGCGCCGGTCGAGTTCATCCGTTTCGCGGAGGAGTCGGGGCTGATCGCGCCGCTCGGGCGCTGGGTGATGCGC
ACGGCCGCGGCGCAGGCCGCCGCCTGGAAGGCGAAGGGGCTGGGCGTGCGGATCGCGGTGAACGTGTCGGCGCGTCAGCT
GCAGGACATGAACATCGTTCATCAGTTCGCGTCGATCGTCGATGCGGCGGGCCTGAAGCCCGGCCTGCTCGACATCGAGC
TGACCGAGAGCTGCTTCATCGACGACGAGCATGGCGCGCACGGGCTGATGAAGCAGTTCCGCCAGCTCGGCGCGAAGATT
CATCTCGACGATTTCGGCACCGGCTATTCGTCGCTGTCGCAACTGTCGCGGCTGCCGCTCGATGCGATCAAGCTCGACCG
CAGCTTCATCACCGGCATCGATCGCAATCCGCGTTCGCAGGCGCTCGTGCGCTCGGTCGTGTCGCTTGCGAATGCGCTCA
ACTTCTCGGTGATCGCGGAAGGCGTCGAGACGCATGCGGAAGCCGAGTTCCTGAAGCAGGTCGATGTCGGCCACGCGCAG
GGCTATTACTTCGCGCGGCCGATGCCCGCCCACGCGTTCGAGGCGTGGCTCGCGGAGACGAGAAAGCTCAGGCTGATCGC
CTGA

Upstream 100 bases:

>100_bases
ATCACGGCTGCCCGGCCCGCACGCGTCGCGCGTGCGCGCCCGGCGGGCGGCGTGCTCGTCTCCGTCTACACTGTGCGTTT
TTTTTGGGTCGGGGCGTGTC

Downstream 100 bases:

>100_bases
GCGTTCCCGAACCGGCTGTCGCCGCAAGGCGACAGCCGTTGCATCACACCGTGCGCAACTTCGACACGCGGCGGTTCTGC
AGCATCACGAGGCGTTCCAT

Product: RNase II stability modulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 667; Mature: 667

Protein sequence:

>667_residues
MDDENDSAVLEAHVGTRSPCWRLGSDSNALELAAVRGMTNVSVALTGEQAARIRALTGVTSHLVLDIVLFGERVPLHLVG
RKVNTTDWAGTASAYSDTVSVASDLAHGLAFAEQVVSEVNSLVVILDRNGMVQRFNRLCEEVTGKREVDVIGRSAFELFM
SPEQGAQSRSNITGFFASNRAFSVERYINTVNGPRLFQFRNKFVQSGSGAEEQYLICSGIDITEERNAQQRLTELANTDV
LTGLPNRHAISERIRTVIAQQTGDTPGQVGILFLDLDNFKRVNDHYGHITGDRLLQDVSAIISGCLPSGATLARLGGDEF
LVLFEQGTRALLEATAQIILERLRTPIHLGLMEVYTSCSIGIAMHPQHGDSLETLIRNADTAMYVAKEAGKHTYRVFSLE
MNQRVAKYMWLDTNLRKALEEEQFVLHYQPVVDIATGDVHAVEALIRWQSPDRGLVAPVEFIRFAEESGLIAPLGRWVMR
TAAAQAAAWKAKGLGVRIAVNVSARQLQDMNIVHQFASIVDAAGLKPGLLDIELTESCFIDDEHGAHGLMKQFRQLGAKI
HLDDFGTGYSSLSQLSRLPLDAIKLDRSFITGIDRNPRSQALVRSVVSLANALNFSVIAEGVETHAEAEFLKQVDVGHAQ
GYYFARPMPAHAFEAWLAETRKLRLIA

Sequences:

>Translated_667_residues
MDDENDSAVLEAHVGTRSPCWRLGSDSNALELAAVRGMTNVSVALTGEQAARIRALTGVTSHLVLDIVLFGERVPLHLVG
RKVNTTDWAGTASAYSDTVSVASDLAHGLAFAEQVVSEVNSLVVILDRNGMVQRFNRLCEEVTGKREVDVIGRSAFELFM
SPEQGAQSRSNITGFFASNRAFSVERYINTVNGPRLFQFRNKFVQSGSGAEEQYLICSGIDITEERNAQQRLTELANTDV
LTGLPNRHAISERIRTVIAQQTGDTPGQVGILFLDLDNFKRVNDHYGHITGDRLLQDVSAIISGCLPSGATLARLGGDEF
LVLFEQGTRALLEATAQIILERLRTPIHLGLMEVYTSCSIGIAMHPQHGDSLETLIRNADTAMYVAKEAGKHTYRVFSLE
MNQRVAKYMWLDTNLRKALEEEQFVLHYQPVVDIATGDVHAVEALIRWQSPDRGLVAPVEFIRFAEESGLIAPLGRWVMR
TAAAQAAAWKAKGLGVRIAVNVSARQLQDMNIVHQFASIVDAAGLKPGLLDIELTESCFIDDEHGAHGLMKQFRQLGAKI
HLDDFGTGYSSLSQLSRLPLDAIKLDRSFITGIDRNPRSQALVRSVVSLANALNFSVIAEGVETHAEAEFLKQVDVGHAQ
GYYFARPMPAHAFEAWLAETRKLRLIA
>Mature_667_residues
MDDENDSAVLEAHVGTRSPCWRLGSDSNALELAAVRGMTNVSVALTGEQAARIRALTGVTSHLVLDIVLFGERVPLHLVG
RKVNTTDWAGTASAYSDTVSVASDLAHGLAFAEQVVSEVNSLVVILDRNGMVQRFNRLCEEVTGKREVDVIGRSAFELFM
SPEQGAQSRSNITGFFASNRAFSVERYINTVNGPRLFQFRNKFVQSGSGAEEQYLICSGIDITEERNAQQRLTELANTDV
LTGLPNRHAISERIRTVIAQQTGDTPGQVGILFLDLDNFKRVNDHYGHITGDRLLQDVSAIISGCLPSGATLARLGGDEF
LVLFEQGTRALLEATAQIILERLRTPIHLGLMEVYTSCSIGIAMHPQHGDSLETLIRNADTAMYVAKEAGKHTYRVFSLE
MNQRVAKYMWLDTNLRKALEEEQFVLHYQPVVDIATGDVHAVEALIRWQSPDRGLVAPVEFIRFAEESGLIAPLGRWVMR
TAAAQAAAWKAKGLGVRIAVNVSARQLQDMNIVHQFASIVDAAGLKPGLLDIELTESCFIDDEHGAHGLMKQFRQLGAKI
HLDDFGTGYSSLSQLSRLPLDAIKLDRSFITGIDRNPRSQALVRSVVSLANALNFSVIAEGVETHAEAEFLKQVDVGHAQ
GYYFARPMPAHAFEAWLAETRKLRLIA

Specific function: Part of a 2 protein system that seems to be dedicated to transcription of csgD. This protein decreases csgD transcription and thus decreases expression of adhesive curli fimbriae genes csgEFG, csgBAC/ymaD and adrA (yaic). Activity of this protein is antag

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=657, Percent_Identity=53.5768645357686, Blast_Score=713, Evalue=0.0,
Organism=Escherichia coli, GI87081921, Length=471, Percent_Identity=29.2993630573248, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI226510982, Length=421, Percent_Identity=30.166270783848, Blast_Score=205, Evalue=7e-54,
Organism=Escherichia coli, GI1790496, Length=252, Percent_Identity=30.5555555555556, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1787055, Length=254, Percent_Identity=36.6141732283465, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI87081743, Length=242, Percent_Identity=31.404958677686, Blast_Score=148, Evalue=9e-37,
Organism=Escherichia coli, GI87081845, Length=235, Percent_Identity=36.5957446808511, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788502, Length=243, Percent_Identity=34.156378600823, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI87081980, Length=267, Percent_Identity=29.5880149812734, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1786507, Length=237, Percent_Identity=33.3333333333333, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788849, Length=441, Percent_Identity=24.4897959183673, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI87082096, Length=420, Percent_Identity=25.952380952381, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI87081977, Length=194, Percent_Identity=33.5051546391753, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788381, Length=438, Percent_Identity=24.4292237442922, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI145693134, Length=158, Percent_Identity=37.3417721518987, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87081881, Length=209, Percent_Identity=30.622009569378, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI87082007, Length=178, Percent_Identity=34.2696629213483, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788956, Length=169, Percent_Identity=37.8698224852071, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787816, Length=165, Percent_Identity=30.9090909090909, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787056, Length=167, Percent_Identity=31.1377245508982, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1787262, Length=168, Percent_Identity=33.9285714285714, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789650, Length=441, Percent_Identity=21.7687074829932, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787802, Length=166, Percent_Identity=27.1084337349398, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786584, Length=173, Percent_Identity=30.635838150289, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF00989 PAS [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 73312; Mature: 73312

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50112 PAS ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDENDSAVLEAHVGTRSPCWRLGSDSNALELAAVRGMTNVSVALTGEQAARIRALTGVT
CCCCCCCEEEEEECCCCCCCEECCCCCCCEEHHHHCCCCEEEEEEECCHHHHHHHHHHHH
SHLVLDIVLFGERVPLHLVGRKVNTTDWAGTASAYSDTVSVASDLAHGLAFAEQVVSEVN
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SLVVILDRNGMVQRFNRLCEEVTGKREVDVIGRSAFELFMSPEQGAQSRSNITGFFASNR
CEEEEECCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCC
AFSVERYINTVNGPRLFQFRNKFVQSGSGAEEQYLICSGIDITEERNAQQRLTELANTDV
CEEHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHCCHHHHHHHHHCCCC
LTGLPNRHAISERIRTVIAQQTGDTPGQVGILFLDLDNFKRVNDHYGHITGDRLLQDVSA
CCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHCCCCCCCCHHHHHHHHHH
IISGCLPSGATLARLGGDEFLVLFEQGTRALLEATAQIILERLRTPIHLGLMEVYTSCSI
HHHHCCCCCCEEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
GIAMHPQHGDSLETLIRNADTAMYVAKEAGKHTYRVFSLEMNQRVAKYMWLDTNLRKALE
CEEECCCCCCHHHHHHHCCCHHEEEEHHCCCCEEEEEEEEHHHHHHHHHEECHHHHHHHC
EEQFVLHYQPVVDIATGDVHAVEALIRWQSPDRGLVAPVEFIRFAEESGLIAPLGRWVMR
CCCEEEEECCEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
TAAAQAAAWKAKGLGVRIAVNVSARQLQDMNIVHQFASIVDAAGLKPGLLDIELTESCFI
HHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHCC
DDEHGAHGLMKQFRQLGAKIHLDDFGTGYSSLSQLSRLPLDAIKLDRSFITGIDRNPRSQ
CCCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCHHHHHHCHHHHCCCCCCCHHH
ALVRSVVSLANALNFSVIAEGVETHAEAEFLKQVDVGHAQGYYFARPMPAHAFEAWLAET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHC
RKLRLIA
CCEEECC
>Mature Secondary Structure
MDDENDSAVLEAHVGTRSPCWRLGSDSNALELAAVRGMTNVSVALTGEQAARIRALTGVT
CCCCCCCEEEEEECCCCCCCEECCCCCCCEEHHHHCCCCEEEEEEECCHHHHHHHHHHHH
SHLVLDIVLFGERVPLHLVGRKVNTTDWAGTASAYSDTVSVASDLAHGLAFAEQVVSEVN
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SLVVILDRNGMVQRFNRLCEEVTGKREVDVIGRSAFELFMSPEQGAQSRSNITGFFASNR
CEEEEECCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCC
AFSVERYINTVNGPRLFQFRNKFVQSGSGAEEQYLICSGIDITEERNAQQRLTELANTDV
CEEHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHCCHHHHHHHHHCCCC
LTGLPNRHAISERIRTVIAQQTGDTPGQVGILFLDLDNFKRVNDHYGHITGDRLLQDVSA
CCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHCCCCCCCCHHHHHHHHHH
IISGCLPSGATLARLGGDEFLVLFEQGTRALLEATAQIILERLRTPIHLGLMEVYTSCSI
HHHHCCCCCCEEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
GIAMHPQHGDSLETLIRNADTAMYVAKEAGKHTYRVFSLEMNQRVAKYMWLDTNLRKALE
CEEECCCCCCHHHHHHHCCCHHEEEEHHCCCCEEEEEEEEHHHHHHHHHEECHHHHHHHC
EEQFVLHYQPVVDIATGDVHAVEALIRWQSPDRGLVAPVEFIRFAEESGLIAPLGRWVMR
CCCEEEEECCEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
TAAAQAAAWKAKGLGVRIAVNVSARQLQDMNIVHQFASIVDAAGLKPGLLDIELTESCFI
HHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHCC
DDEHGAHGLMKQFRQLGAKIHLDDFGTGYSSLSQLSRLPLDAIKLDRSFITGIDRNPRSQ
CCCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCHHHHHHCHHHHCCCCCCCHHH
ALVRSVVSLANALNFSVIAEGVETHAEAEFLKQVDVGHAQGYYFARPMPAHAFEAWLAET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHC
RKLRLIA
CCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]