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The map label for this gene is mraY

Identifier: 189184779

GI number: 189184779

Start: 1911385

End: 1912476

Strand: Reverse

Name: mraY

Synonym: OTT_1872

Alternate gene names: 189184779

Gene position: 1912476-1911385 (Counterclockwise)

Preceding gene: 189184780

Following gene: 189184778

Centisome position: 95.2

GC content: 29.49

Gene sequence:

>1092_bases
ATGCTATATAATTTACTCGTATCGCATATAAATAGCTGTTATATTTTCAGTATTTTTTATAATGTTATAGTAAGAAGTGG
AATAGCTATATTACTAAGCTTTAGTATATCATTTTCTCTAATTCCTATTCTAATTAAATATTTTAAGTATTGGAAAAATT
TAGCACAGCCTATTAGAAACCTTGGGCATAAAAGTCACATAGCTAAAGCTGGTACGCCGACAATGGGAGGAATTGCAATT
ATATTTTCAATAATAATATCAACCTTAATGCTAGCTGATTACAAAAACATTTATGTACTAACAACCATATTTGGAATGCT
TAGTTTAGCAATTTTAGGATTAATTGATGATTATCAGAAAGTAACAAAGAAAAATACAAAAGGGATTAATGCTACTTGCA
AATTGATTAGCCAAATTATGGTAAGTATAATTTGTTGTATGATTGTTAACTATAATCTAAATTCAGAAATAGCAAATCAT
TTAATAATTCCATTTTTTAAGAAATTAACTATTGATTTGTCTATATTTTATATTCCATTTGCTTTGTTTATAATTATTGG
ATCATCGAATGCAGTAAACTTAACTGATGGACTAGATGGATTGGTTACTGTGCCAATTATTATAGTATCTTTCTGTCTAG
GACTGATGTGTTACTTAGCTGACAACGCGCAATATATCAATATTAATCACTTGCAAATTTTGCATGTACAACAAGCTTCA
GAACTGACAGTACTATGTTCTGCTATAATTGGAGCAAGCTTAGGGTTTTTATGGTATAATATTCAGCCAGCTAAAATATT
CATGGGAGATGTTGGTAGTTTATCACTTGGCGGTGCTATTGGTATAATCAGTGTAATTAGTAAAAATGAAATCAGGCTAG
GTATCATTGGAGGCTTATTTGTAATAGAAGCGTTATCAGCTATAATTCAAATATATTCTATTAGATATTTGGGAGGAAAA
CGCGTTTTTAAAATGGCGCCTATACATCATCATTTTGAACAAATAGGGTGGAGCGAATCTAAGATAGTAAGTAGATTTTG
GCTTTTATCAATAATTTTTTCGCTGATTGGCCTGTCTAGTTTAATATTATAG

Upstream 100 bases:

>100_bases
CCATTACTACATGATAAAGATTATGTTTTAATTAAAGGATCAAACCGCATGAGGCTTTGGCAGGTCGTCGAAAATTTACT
TGAATCTGGAATGTTAAAAG

Downstream 100 bases:

>100_bases
CACTTTCTACAGTATTTAGAAGCAACTCAAGCAAAATTATGATTGTGAAAATAACATATTGCTTATAGTTTAAACAATCA
AAAAGCCAGTATTTTATATC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MLYNLLVSHINSCYIFSIFYNVIVRSGIAILLSFSISFSLIPILIKYFKYWKNLAQPIRNLGHKSHIAKAGTPTMGGIAI
IFSIIISTLMLADYKNIYVLTTIFGMLSLAILGLIDDYQKVTKKNTKGINATCKLISQIMVSIICCMIVNYNLNSEIANH
LIIPFFKKLTIDLSIFYIPFALFIIIGSSNAVNLTDGLDGLVTVPIIIVSFCLGLMCYLADNAQYININHLQILHVQQAS
ELTVLCSAIIGASLGFLWYNIQPAKIFMGDVGSLSLGGAIGIISVISKNEIRLGIIGGLFVIEALSAIIQIYSIRYLGGK
RVFKMAPIHHHFEQIGWSESKIVSRFWLLSIIFSLIGLSSLIL

Sequences:

>Translated_363_residues
MLYNLLVSHINSCYIFSIFYNVIVRSGIAILLSFSISFSLIPILIKYFKYWKNLAQPIRNLGHKSHIAKAGTPTMGGIAI
IFSIIISTLMLADYKNIYVLTTIFGMLSLAILGLIDDYQKVTKKNTKGINATCKLISQIMVSIICCMIVNYNLNSEIANH
LIIPFFKKLTIDLSIFYIPFALFIIIGSSNAVNLTDGLDGLVTVPIIIVSFCLGLMCYLADNAQYININHLQILHVQQAS
ELTVLCSAIIGASLGFLWYNIQPAKIFMGDVGSLSLGGAIGIISVISKNEIRLGIIGGLFVIEALSAIIQIYSIRYLGGK
RVFKMAPIHHHFEQIGWSESKIVSRFWLLSIIFSLIGLSSLIL
>Mature_363_residues
MLYNLLVSHINSCYIFSIFYNVIVRSGIAILLSFSISFSLIPILIKYFKYWKNLAQPIRNLGHKSHIAKAGTPTMGGIAI
IFSIIISTLMLADYKNIYVLTTIFGMLSLAILGLIDDYQKVTKKNTKGINATCKLISQIMVSIICCMIVNYNLNSEIANH
LIIPFFKKLTIDLSIFYIPFALFIIIGSSNAVNLTDGLDGLVTVPIIIVSFCLGLMCYLADNAQYININHLQILHVQQAS
ELTVLCSAIIGASLGFLWYNIQPAKIFMGDVGSLSLGGAIGIISVISKNEIRLGIIGGLFVIEALSAIIQIYSIRYLGGK
RVFKMAPIHHHFEQIGWSESKIVSRFWLLSIIFSLIGLSSLIL

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=357, Percent_Identity=41.4565826330532, Blast_Score=290, Evalue=8e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_ORITI (B3CVD3)

Other databases:

- EMBL:   AP008981
- RefSeq:   YP_001938564.1
- GeneID:   6337995
- GenomeReviews:   AP008981_GR
- KEGG:   ott:OTT_1872
- HOGENOM:   HBG708263
- OMA:   RSPARIF
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 40153; Mature: 40153

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91f9ed4)-; HASH(0x1da11938)-; HASH(0x40719c90)-; HASH(0x1dabdacc)-; HASH(0x1da1662c)-; HASH(0x1cbca990)-; HASH(0x1da14048)-; HASH(0x1cb67e5c)-; HASH(0x1da118d8)-; HASH(0x1d930f14)-; HASH(0x1da0f078)-;

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYNLLVSHINSCYIFSIFYNVIVRSGIAILLSFSISFSLIPILIKYFKYWKNLAQPIRN
CHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGHKSHIAKAGTPTMGGIAIIFSIIISTLMLADYKNIYVLTTIFGMLSLAILGLIDDYQK
CCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VTKKNTKGINATCKLISQIMVSIICCMIVNYNLNSEIANHLIIPFFKKLTIDLSIFYIPF
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALFIIIGSSNAVNLTDGLDGLVTVPIIIVSFCLGLMCYLADNAQYININHLQILHVQQAS
HHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCHH
ELTVLCSAIIGASLGFLWYNIQPAKIFMGDVGSLSLGGAIGIISVISKNEIRLGIIGGLF
HHHHHHHHHHHHHHHHHEEECCCHHEEECCCCCCCCCHHHHHHHHHCCCCEEEEHHHHHH
VIEALSAIIQIYSIRYLGGKRVFKMAPIHHHFEQIGWSESKIVSRFWLLSIIFSLIGLSS
HHHHHHHHHHHHHHHCCCCCHHEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LIL
HCH
>Mature Secondary Structure
MLYNLLVSHINSCYIFSIFYNVIVRSGIAILLSFSISFSLIPILIKYFKYWKNLAQPIRN
CHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGHKSHIAKAGTPTMGGIAIIFSIIISTLMLADYKNIYVLTTIFGMLSLAILGLIDDYQK
CCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VTKKNTKGINATCKLISQIMVSIICCMIVNYNLNSEIANHLIIPFFKKLTIDLSIFYIPF
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALFIIIGSSNAVNLTDGLDGLVTVPIIIVSFCLGLMCYLADNAQYININHLQILHVQQAS
HHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEECCHH
ELTVLCSAIIGASLGFLWYNIQPAKIFMGDVGSLSLGGAIGIISVISKNEIRLGIIGGLF
HHHHHHHHHHHHHHHHHEEECCCHHEEECCCCCCCCCHHHHHHHHHCCCCEEEEHHHHHH
VIEALSAIIQIYSIRYLGGKRVFKMAPIHHHFEQIGWSESKIVSRFWLLSIIFSLIGLSS
HHHHHHHHHHHHHHHCCCCCHHEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LIL
HCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA