Click here to switch to the map view.

The map label for this gene is rsh [H]

Identifier: 189184632

GI number: 189184632

Start: 1747113

End: 1747688

Strand: Reverse

Name: rsh [H]

Synonym: OTT_1725

Alternate gene names: 189184632

Gene position: 1747688-1747113 (Counterclockwise)

Preceding gene: 189184633

Following gene: 189184631

Centisome position: 86.99

GC content: 30.03

Gene sequence:

>576_bases
ATGATAGACTTTTATAGCGAAAGCTTACTAAATAAGCTGTTTGAAACCAACGTAAGATTTAATACTAAAATTGATCTTGA
TAAAGTTGAAAGAGCAATATTTTATGCTAAAAAATATCATGGTCAGCAAAAGAGAGATACAGGAGAACTATACTACACAC
ATCCATTAGAAGTAGCTTATATGGTATCAGACTACAGCTTTGAAACAGATACGATTATTACAGCAATACTACATGATACC
ATCGAAGACACAACACTAACTAAAGAAAAAATAGGTCAAGAATTTGGTCATAATATTGCAGAACAGGTTTCAGACCTCAC
CAGGATTAAGGATAATAAAAAAATTAGTTCTAGAGAGATGATTCAAACATTTTATAGACAAAATAAAACAGAACTATTAT
TAATTAAGCTTTTCGACCGATTCCATAATATTCAAACCATACACATAAAACCTTATGAAAAAAGACAAGAAATCATACTA
GAAACGCAGCAAGAATTTATACCTCTTGCTGAATATCTTAAATTACCAGAAATTGCTATAGAGCTAAATAAATACTGTGA
GCTTTATGCTAGCTAA

Upstream 100 bases:

>100_bases
TCAAATTAATTCGCTTCTTTCACAGTTTTTATCTGAGATTGAAGTATATAAAAAGTTTAATTTATTGTATAATTTATTAA
AGATTATTTAGAGATGAAAA

Downstream 100 bases:

>100_bases
TAAGCTAAAGTTTAATAGGTTGTTAATGTAGTGAATTGCAGAAATTAAAATTCAATAAGAGAATGTTCATGTAAGTTATT
TTATTGTATAATTTAAAAAG

Product: RelA/SpoT-related protein

Products: NA

Alternate protein names: (p)ppGpp synthase; ATP:GTP 3'-pyrophosphotransferase [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MIDFYSESLLNKLFETNVRFNTKIDLDKVERAIFYAKKYHGQQKRDTGELYYTHPLEVAYMVSDYSFETDTIITAILHDT
IEDTTLTKEKIGQEFGHNIAEQVSDLTRIKDNKKISSREMIQTFYRQNKTELLLIKLFDRFHNIQTIHIKPYEKRQEIIL
ETQQEFIPLAEYLKLPEIAIELNKYCELYAS

Sequences:

>Translated_191_residues
MIDFYSESLLNKLFETNVRFNTKIDLDKVERAIFYAKKYHGQQKRDTGELYYTHPLEVAYMVSDYSFETDTIITAILHDT
IEDTTLTKEKIGQEFGHNIAEQVSDLTRIKDNKKISSREMIQTFYRQNKTELLLIKLFDRFHNIQTIHIKPYEKRQEIIL
ETQQEFIPLAEYLKLPEIAIELNKYCELYAS
>Mature_191_residues
MIDFYSESLLNKLFETNVRFNTKIDLDKVERAIFYAKKYHGQQKRDTGELYYTHPLEVAYMVSDYSFETDTIITAILHDT
IEDTTLTKEKIGQEFGHNIAEQVSDLTRIKDNKKISSREMIQTFYRQNKTELLLIKLFDRFHNIQTIHIKPYEKRQEIIL
ETQQEFIPLAEYLKLPEIAIELNKYCELYAS

Specific function: Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. Plays a role in ada

COG id: COG0317

COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HD domain [H]

Homologues:

Organism=Escherichia coli, GI1790082, Length=182, Percent_Identity=34.0659340659341, Blast_Score=93, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25143118, Length=119, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR012675
- InterPro:   IPR003607
- InterPro:   IPR007685
- InterPro:   IPR004811
- InterPro:   IPR004095
- InterPro:   IPR012676 [H]

Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]

EC number: =2.7.6.5 [H]

Molecular weight: Translated: 22760; Mature: 22760

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFYSESLLNKLFETNVRFNTKIDLDKVERAIFYAKKYHGQQKRDTGELYYTHPLEVAY
CCCHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEE
MVSDYSFETDTIITAILHDTIEDTTLTKEKIGQEFGHNIAEQVSDLTRIKDNKKISSREM
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHH
IQTFYRQNKTELLLIKLFDRFHNIQTIHIKPYEKRQEIILETQQEFIPLAEYLKLPEIAI
HHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ELNKYCELYAS
HHHHHHHHHCC
>Mature Secondary Structure
MIDFYSESLLNKLFETNVRFNTKIDLDKVERAIFYAKKYHGQQKRDTGELYYTHPLEVAY
CCCHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEE
MVSDYSFETDTIITAILHDTIEDTTLTKEKIGQEFGHNIAEQVSDLTRIKDNKKISSREM
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHH
IQTFYRQNKTELLLIKLFDRFHNIQTIHIKPYEKRQEIILETQQEFIPLAEYLKLPEIAI
HHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ELNKYCELYAS
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA