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The map label for this gene is ftsK [H]

Identifier: 189183288

GI number: 189183288

Start: 394281

End: 396569

Strand: Direct

Name: ftsK [H]

Synonym: OTT_0381

Alternate gene names: 189183288

Gene position: 394281-396569 (Clockwise)

Preceding gene: 189183287

Following gene: 189183289

Centisome position: 19.63

GC content: 31.5

Gene sequence:

>2289_bases
ATGTTTAATATCTTGAAAATAATATTTGAGGATAGCAGATTCAAGTCTGCGCTTTGCTTTATTACTTCCTTCTTAATTTT
CTTGGTATTATTGTCATATGATAGTAATGATCCTGGATTTAATATCGCGACTAATGTTATACCAAACAACTTGTTAGGGC
ATGCTGGAGCTAATTTTACTAGAATGCTGATAGCTATTTTAGGCTCAACGGCATTTTTTTTTCCAATATTTTTGGTTGCA
TTAGGAAGGAAATATTATTTTCAGCAAGAAATAAGATATTTAAAACTCAAGATTTTATCTGCCATAATAATAATATTGGA
GTGTTCTTATTTTATAAGTAATATTGAGAGCCTAGATTTTCAGTATAAGGGAATTATCGGCAGCAGTATCTATGATTTAG
TCAAAATCTTTAACCATAGCGCTATTATAGGAATTAACAGCATTATGATAGCAATTCTAATAGTTAATCTATCGTTTATT
ATAGACTATCCATTATCAAATATTATACCATTAATACGCTCACTCACTACACATGCTTTTATTTATATAAAAAATTTTTT
TGTTGGACTGATAAGTTTAAAATATTTGACTCGTAATAATAATTCAGATGTGCAGCTACAGCAGCATCAGTTGGTTGTAT
GCAATAATGATAATGATTTGCTAATAAAAGATGAAGAAGATGGTGATGATAACGCTGTGATGCCTAGTGTTTCTCCGTTC
TCTGATAGTAATTTTAGTTGGAATAAAAATAATGATGTGGCTATAAATTATAAGAGTAATACTGACCAAACTATTGTTTT
GCCTGAAGTTGATCTACTAGGACAATATGATAACCGTAATGTAGCACCAGAGAGTGAAGAAAAGTTGATTTATAATTCCA
AACAGTTGTTAAAAATATTGAATGATTTTGGAATTAAAGGGCATATTTTTAACATTAATCAAGGACCAGTTGTTACATTA
TATGAATTTGAACCAGCAGCTGGAACTAAATCTTCACGTGTTATTGGTTTATCTGATGATATAGCTAGGTCTTTAAGTGC
ATTGTCTACCAGAATATCAGTTATTCCAGGTAAAAATGTTTTAGGAATTGAATTACCTAATTTACATAGAATGTTTTTTA
GTATTAGAGAATTGATAGAGTCAGCTGAATATCAAAAATCTGATAAATCTCTGCCAATTATCCTTGGCAAAGATTTAAGT
GGTGAGCCAGAAATAATCGATTTAGCTAAAATGCCTCATTTACTAGTAGCTGGAACAACTGGTTCTGGAAAATCAGTAGC
AATTAATGCTATGATTATTTCATTGCTCTATCGTCTTACTCCTAATGAATGTAAATTTATTATGATTGATCCTAAAATGC
TTGAGTTATCAGTGTATGAAGGCATTCCTCATTTACTTACACCTGTAGTAACTGATCCTAGTAAAGCAATTATTGCTTTA
AAATGGGGAGTTAGAGAAATGGAAAACAGATATAGATTAATGTCCACTTTAGGAGTTAGAAATATTGCTGGTTATAATAG
CAGAATTGAGGAAGCAATTGCTAAAAAGCAAACATTGGCTAAAACTTTACATACTGGTTTTGATCATGAAACAGGGCAAC
CTATATATGAATCAATACCTATTCCATTAGAAAAGTTGCCATTTATAGTTATTATAGTGGATGAAATGGCTGATTTAATG
ATAGTAGCTGGTAAAGACATTGAATCATCAATACAAAGGCTAGCCCAAATGGCAAGAGCTGCTGGAATTCATATTATTAT
GGCAACTCAGCGGCCTTCGGTGGATGTTATTACAGGAGTAATAAAGGCAAATTTCCCAAGTAGAATTAGTTTTAAGGTAA
CATCAAAAATTGATAGTAGAACTATTTTAGGAGAAATGGGAGCTGAGCAGTTACTAGGTATGGGTGATATGTTATATATG
GGTAATGGAACCACTATCAAAAGAGTGCATGCTCCTTTTGTGGATGATAGTGAAGTTGAACAAGTTGCTAAATTTTTAAG
GGCTCAAGCAACTCCGCAGTATATTGATAATATTACTGAGATATCAGATGATAACATAAATATTACTTCTTTTTCATCCA
ATAGTGATGAATCAACAGATGATGAAAGTTTATATAAGCAGGCTGTACAGATCGTTAAAACAGATAAAAGAGTTTCTACG
AGTTATATTCAAAGATGTTTACGAATAGGATATAATAGAGCAGCATTAATAGTTGAAAAAATGGAACGAGAAGGAGTTGT
TAGCCCTCCAAATCATAGTGGCAAAAGGGAGATTTTAATAAAAGAGTAA

Upstream 100 bases:

>100_bases
AGATAGTTAAGTGGCATCGAGTTTATTAGCTTTCTAGCTGTTATTACATCTAAAGTTTCTTATATTACCTATAATGATAT
TGATTTAAGAGAAGATTGTA

Downstream 100 bases:

>100_bases
CAACGCTACTTAATATCAGCTTAGATTTGATAGCATAGCTTACGCAAAAAAGACATTATGAGTTTTTAACTGTGCTTCAT
AACAAAGAACATGTTGCTAC

Product: cell division protein FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 762; Mature: 762

Protein sequence:

>762_residues
MFNILKIIFEDSRFKSALCFITSFLIFLVLLSYDSNDPGFNIATNVIPNNLLGHAGANFTRMLIAILGSTAFFFPIFLVA
LGRKYYFQQEIRYLKLKILSAIIIILECSYFISNIESLDFQYKGIIGSSIYDLVKIFNHSAIIGINSIMIAILIVNLSFI
IDYPLSNIIPLIRSLTTHAFIYIKNFFVGLISLKYLTRNNNSDVQLQQHQLVVCNNDNDLLIKDEEDGDDNAVMPSVSPF
SDSNFSWNKNNDVAINYKSNTDQTIVLPEVDLLGQYDNRNVAPESEEKLIYNSKQLLKILNDFGIKGHIFNINQGPVVTL
YEFEPAAGTKSSRVIGLSDDIARSLSALSTRISVIPGKNVLGIELPNLHRMFFSIRELIESAEYQKSDKSLPIILGKDLS
GEPEIIDLAKMPHLLVAGTTGSGKSVAINAMIISLLYRLTPNECKFIMIDPKMLELSVYEGIPHLLTPVVTDPSKAIIAL
KWGVREMENRYRLMSTLGVRNIAGYNSRIEEAIAKKQTLAKTLHTGFDHETGQPIYESIPIPLEKLPFIVIIVDEMADLM
IVAGKDIESSIQRLAQMARAAGIHIIMATQRPSVDVITGVIKANFPSRISFKVTSKIDSRTILGEMGAEQLLGMGDMLYM
GNGTTIKRVHAPFVDDSEVEQVAKFLRAQATPQYIDNITEISDDNINITSFSSNSDESTDDESLYKQAVQIVKTDKRVST
SYIQRCLRIGYNRAALIVEKMEREGVVSPPNHSGKREILIKE

Sequences:

>Translated_762_residues
MFNILKIIFEDSRFKSALCFITSFLIFLVLLSYDSNDPGFNIATNVIPNNLLGHAGANFTRMLIAILGSTAFFFPIFLVA
LGRKYYFQQEIRYLKLKILSAIIIILECSYFISNIESLDFQYKGIIGSSIYDLVKIFNHSAIIGINSIMIAILIVNLSFI
IDYPLSNIIPLIRSLTTHAFIYIKNFFVGLISLKYLTRNNNSDVQLQQHQLVVCNNDNDLLIKDEEDGDDNAVMPSVSPF
SDSNFSWNKNNDVAINYKSNTDQTIVLPEVDLLGQYDNRNVAPESEEKLIYNSKQLLKILNDFGIKGHIFNINQGPVVTL
YEFEPAAGTKSSRVIGLSDDIARSLSALSTRISVIPGKNVLGIELPNLHRMFFSIRELIESAEYQKSDKSLPIILGKDLS
GEPEIIDLAKMPHLLVAGTTGSGKSVAINAMIISLLYRLTPNECKFIMIDPKMLELSVYEGIPHLLTPVVTDPSKAIIAL
KWGVREMENRYRLMSTLGVRNIAGYNSRIEEAIAKKQTLAKTLHTGFDHETGQPIYESIPIPLEKLPFIVIIVDEMADLM
IVAGKDIESSIQRLAQMARAAGIHIIMATQRPSVDVITGVIKANFPSRISFKVTSKIDSRTILGEMGAEQLLGMGDMLYM
GNGTTIKRVHAPFVDDSEVEQVAKFLRAQATPQYIDNITEISDDNINITSFSSNSDESTDDESLYKQAVQIVKTDKRVST
SYIQRCLRIGYNRAALIVEKMEREGVVSPPNHSGKREILIKE
>Mature_762_residues
MFNILKIIFEDSRFKSALCFITSFLIFLVLLSYDSNDPGFNIATNVIPNNLLGHAGANFTRMLIAILGSTAFFFPIFLVA
LGRKYYFQQEIRYLKLKILSAIIIILECSYFISNIESLDFQYKGIIGSSIYDLVKIFNHSAIIGINSIMIAILIVNLSFI
IDYPLSNIIPLIRSLTTHAFIYIKNFFVGLISLKYLTRNNNSDVQLQQHQLVVCNNDNDLLIKDEEDGDDNAVMPSVSPF
SDSNFSWNKNNDVAINYKSNTDQTIVLPEVDLLGQYDNRNVAPESEEKLIYNSKQLLKILNDFGIKGHIFNINQGPVVTL
YEFEPAAGTKSSRVIGLSDDIARSLSALSTRISVIPGKNVLGIELPNLHRMFFSIRELIESAEYQKSDKSLPIILGKDLS
GEPEIIDLAKMPHLLVAGTTGSGKSVAINAMIISLLYRLTPNECKFIMIDPKMLELSVYEGIPHLLTPVVTDPSKAIIAL
KWGVREMENRYRLMSTLGVRNIAGYNSRIEEAIAKKQTLAKTLHTGFDHETGQPIYESIPIPLEKLPFIVIIVDEMADLM
IVAGKDIESSIQRLAQMARAAGIHIIMATQRPSVDVITGVIKANFPSRISFKVTSKIDSRTILGEMGAEQLLGMGDMLYM
GNGTTIKRVHAPFVDDSEVEQVAKFLRAQATPQYIDNITEISDDNINITSFSSNSDESTDDESLYKQAVQIVKTDKRVST
SYIQRCLRIGYNRAALIVEKMEREGVVSPPNHSGKREILIKE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=505, Percent_Identity=51.0891089108911, Blast_Score=484, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 85151; Mature: 85151

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNILKIIFEDSRFKSALCFITSFLIFLVLLSYDSNDPGFNIATNVIPNNLLGHAGANFT
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHCCCCHHH
RMLIAILGSTAFFFPIFLVALGRKYYFQQEIRYLKLKILSAIIIILECSYFISNIESLDF
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
QYKGIIGSSIYDLVKIFNHSAIIGINSIMIAILIVNLSFIIDYPLSNIIPLIRSLTTHAF
EEECCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
IYIKNFFVGLISLKYLTRNNNSDVQLQQHQLVVCNNDNDLLIKDEEDGDDNAVMPSVSPF
HHHHHHHHHHHHHHHEECCCCCCEEEEEEEEEEEECCCEEEEECCCCCCCCCCCCCCCCC
SDSNFSWNKNNDVAINYKSNTDQTIVLPEVDLLGQYDNRNVAPESEEKLIYNSKQLLKIL
CCCCCCCCCCCCEEEEECCCCCCEEEECCHHHHCCCCCCCCCCCCCCHHHHCHHHHHHHH
NDFGIKGHIFNINQGPVVTLYEFEPAAGTKSSRVIGLSDDIARSLSALSTRISVIPGKNV
HHCCCCEEEEEECCCCEEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHEEEEECCCCE
LGIELPNLHRMFFSIRELIESAEYQKSDKSLPIILGKDLSGEPEIIDLAKMPHLLVAGTT
EEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCEEECCCCCEEEEEECC
GSGKSVAINAMIISLLYRLTPNECKFIMIDPKMLELSVYEGIPHLLTPVVTDPSKAIIAL
CCCCEEEHHHHHHHHHHHCCCCCCEEEEECCCEEEEEHHHCCHHHHCCCCCCCCCEEEEE
KWGVREMENRYRLMSTLGVRNIAGYNSRIEEAIAKKQTLAKTLHTGFDHETGQPIYESIP
ECCHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCC
IPLEKLPFIVIIVDEMADLMIVAGKDIESSIQRLAQMARAAGIHIIMATQRPSVDVITGV
CCHHHCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
IKANFPSRISFKVTSKIDSRTILGEMGAEQLLGMGDMLYMGNGTTIKRVHAPFVDDSEVE
HHCCCCCCEEEEEECCCCCHHHHHHCCHHHHHCCCCEEEECCCCEEEEEECCCCCCHHHH
QVAKFLRAQATPQYIDNITEISDDNINITSFSSNSDESTDDESLYKQAVQIVKTDKRVST
HHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHH
SYIQRCLRIGYNRAALIVEKMEREGVVSPPNHSGKREILIKE
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEC
>Mature Secondary Structure
MFNILKIIFEDSRFKSALCFITSFLIFLVLLSYDSNDPGFNIATNVIPNNLLGHAGANFT
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHCCCCHHH
RMLIAILGSTAFFFPIFLVALGRKYYFQQEIRYLKLKILSAIIIILECSYFISNIESLDF
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
QYKGIIGSSIYDLVKIFNHSAIIGINSIMIAILIVNLSFIIDYPLSNIIPLIRSLTTHAF
EEECCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
IYIKNFFVGLISLKYLTRNNNSDVQLQQHQLVVCNNDNDLLIKDEEDGDDNAVMPSVSPF
HHHHHHHHHHHHHHHEECCCCCCEEEEEEEEEEEECCCEEEEECCCCCCCCCCCCCCCCC
SDSNFSWNKNNDVAINYKSNTDQTIVLPEVDLLGQYDNRNVAPESEEKLIYNSKQLLKIL
CCCCCCCCCCCCEEEEECCCCCCEEEECCHHHHCCCCCCCCCCCCCCHHHHCHHHHHHHH
NDFGIKGHIFNINQGPVVTLYEFEPAAGTKSSRVIGLSDDIARSLSALSTRISVIPGKNV
HHCCCCEEEEEECCCCEEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHEEEEECCCCE
LGIELPNLHRMFFSIRELIESAEYQKSDKSLPIILGKDLSGEPEIIDLAKMPHLLVAGTT
EEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCEEECCCCCEEEEEECC
GSGKSVAINAMIISLLYRLTPNECKFIMIDPKMLELSVYEGIPHLLTPVVTDPSKAIIAL
CCCCEEEHHHHHHHHHHHCCCCCCEEEEECCCEEEEEHHHCCHHHHCCCCCCCCCEEEEE
KWGVREMENRYRLMSTLGVRNIAGYNSRIEEAIAKKQTLAKTLHTGFDHETGQPIYESIP
ECCHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCC
IPLEKLPFIVIIVDEMADLMIVAGKDIESSIQRLAQMARAAGIHIIMATQRPSVDVITGV
CCHHHCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
IKANFPSRISFKVTSKIDSRTILGEMGAEQLLGMGDMLYMGNGTTIKRVHAPFVDDSEVE
HHCCCCCCEEEEEECCCCCHHHHHHCCHHHHHCCCCEEEECCCCEEEEEECCCCCCHHHH
QVAKFLRAQATPQYIDNITEISDDNINITSFSSNSDESTDDESLYKQAVQIVKTDKRVST
HHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHH
SYIQRCLRIGYNRAALIVEKMEREGVVSPPNHSGKREILIKE
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA