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The map label for this gene is htpG

Identifier: 189026207

GI number: 189026207

Start: 1068084

End: 1070003

Strand: Reverse

Name: htpG

Synonym: TPASS_0984

Alternate gene names: 189026207

Gene position: 1070003-1068084 (Counterclockwise)

Preceding gene: 189026210

Following gene: 189026198

Centisome position: 93.9

GC content: 48.28

Gene sequence:

>1920_bases
ATGGCTCAGTACGAGTTTCAAACTGAAGTGAGTCAGCTGCTAACGTTGATTATCCATTCTCTCTATTCCCATAAAGAGAT
TTTTCTCCGGGAACTTATCTCTAATGCGTCGGATGCGTTAGATAAGTTGAAGTATGAGGCACTTGTTGATGGTACGTACA
AGCAGTTGCATTGCGAAGCGCGTATAGACATCGCGTTTGAAGAAGATGCTCAACGGCTTGTTGTGCGTGATACGGGTATT
GGCATGAACGCAGAAGATCTGAGGGCCAATCTAGGTACCATTGCGCGATCCGGTACAAAGGCGTTTCTCAGTACGCTGAC
GCGTGATCAAAAACAGGATTCCAATCTGATAGGCCAGTTTGGCGTAGGGTTTTACTCTGCCTTCATGGTCGCTTCCAAAG
TAGAAGTAATCACCAAGAAAGCTGCAGAGAACACCGTGTGGAAGTGGACGTCTGAAGGGCAAAATGCCTATACCTTGGAT
GAGGTTGATGCGGCTGCCTTCCCAGTACTTGAAGGGGTTGCTGAGGGTAGTGCCGGTACCTGCGTTGTGTTGCACCTGAG
CCAGGAAAATTCCGAGTTTGCAACGCGCTGGCGTCTTGAAGAGGTAATTAAGAAGTATTCTGATCATATCGCGTTTCCCA
TCTATCTGCATTACCTGCAGAAGGAGTACGACAAGGATGGAGCGGTAACGGATACTCAGAAGAAAGTAGATCAAGTCAAT
GACGCGGGTGCGTTGTGGAAAAGGCCGAAGTCAGAATTGAAGGAGGAGGATTATCATCGTTTCTATCAAACGCTGACTCG
CGACAGTACTCCGCCTCTCTTGTACGTACACACGAAGGCAGAGGGTACACAGGAGTACGTCACGCTCTTTTATGTGCCGG
CAAAAGCGCCCTTTGACCTTTTTCACGCAGATTATAAGCCGGGGGTAAAGCTCTTCGTTAAGCGCGTTTTCATCACTGAT
GACGAGAAGGAACTGTTGCCAGTGTATCTGCGTTTTGTCCGCGGTGTAATAGACAGCGAAGATCTGCCCCTGAATGTAAG
CCGTGAGATTCTGCAACAAAATAGAGTCCTTGCAGCAATCAAGTCGGCTTCGGTGAAAAAGTTGCTCGGGGAATTTAAGA
GACTCGCGGAGTGTGACGGGAAAAAGTACGATGAGTTTATCACGCAGTATAATCGTCCCTTGAAGGAGGGTTTATACAGC
GACTACGAGCACCGTGAGCAGCTGCTGGAACTTGTTCGTTTCAGGACTCTAAGTGAGTCTGTTCCAGAAGACGGATGGAC
GAGCTTCGCCGAATACGTTTCTCGCATGAAACCGGATCAAAAGGCGATATACTACATTGCGGGAAACGACGATCGTGTGC
TGCGTCAGTCTCCCCATGCAGAGTCTTATCGTTTGCAGGGTTTTGAAGTGCTCGTTATGTCAGACGACATAGATGGTATC
GTGATGCCCTCTGTTTCGAAATACAAGGAGTGGGAGTTAAGGGCAATTAATCGTTTAGGTTCAGAGGAGGAGTTGCGTCC
CAACGAAGAAACAGACGCCGCCGCGCAGAGGGAACAGGGTTTTAAGCCGCTACTAGAAAGGTTGACGCACATACTGTCTG
ATTCGGTGAAGGAAGTTCGTCTTTCAAAACGGCTTTCTGACTCGGTGTCTTGCATTGTTATCGATGAGAATGATCCCACG
GTGCAGATGGAGCGCTTGATGCGCGCCACGGGACAAACGCATAAATCAAAGATAAAGCCAATTTTAGAAATTAACGCAAG
TCATACGCTGGTACAAAAACTAAAAGAAAGTACGGATGAGGCGTTTGTGGAAGATCTTGCGTTTGTTCTTCTGGATCAAG
CCTTGCTCATTGAAGGCATGGACGTAGGTTCGTCGGTTGATTTTGTGAAGCGGGTGAACCGTCTGCTCGCACGCGGGTAG

Upstream 100 bases:

>100_bases
CCTGTTCCGGTTGGTTTACTGTGCTGCATAGTCTGTGCTACACTTCGCGCGCGGTCTGTGCGCGGCGTAATGGAATCTTT
TTTAACCTCTGGGAGGATAC

Downstream 100 bases:

>100_bases
CGGTCAGGACTCGGTGCGTGCTACTAGTATACGCTATAGGGCGTTATCTTTGTGAAGTGGACACTGAGTGAGAGCTCTGC
GACAAATTCCCCCGCCTCTA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 639; Mature: 638

Protein sequence:

>639_residues
MAQYEFQTEVSQLLTLIIHSLYSHKEIFLRELISNASDALDKLKYEALVDGTYKQLHCEARIDIAFEEDAQRLVVRDTGI
GMNAEDLRANLGTIARSGTKAFLSTLTRDQKQDSNLIGQFGVGFYSAFMVASKVEVITKKAAENTVWKWTSEGQNAYTLD
EVDAAAFPVLEGVAEGSAGTCVVLHLSQENSEFATRWRLEEVIKKYSDHIAFPIYLHYLQKEYDKDGAVTDTQKKVDQVN
DAGALWKRPKSELKEEDYHRFYQTLTRDSTPPLLYVHTKAEGTQEYVTLFYVPAKAPFDLFHADYKPGVKLFVKRVFITD
DEKELLPVYLRFVRGVIDSEDLPLNVSREILQQNRVLAAIKSASVKKLLGEFKRLAECDGKKYDEFITQYNRPLKEGLYS
DYEHREQLLELVRFRTLSESVPEDGWTSFAEYVSRMKPDQKAIYYIAGNDDRVLRQSPHAESYRLQGFEVLVMSDDIDGI
VMPSVSKYKEWELRAINRLGSEEELRPNEETDAAAQREQGFKPLLERLTHILSDSVKEVRLSKRLSDSVSCIVIDENDPT
VQMERLMRATGQTHKSKIKPILEINASHTLVQKLKESTDEAFVEDLAFVLLDQALLIEGMDVGSSVDFVKRVNRLLARG

Sequences:

>Translated_639_residues
MAQYEFQTEVSQLLTLIIHSLYSHKEIFLRELISNASDALDKLKYEALVDGTYKQLHCEARIDIAFEEDAQRLVVRDTGI
GMNAEDLRANLGTIARSGTKAFLSTLTRDQKQDSNLIGQFGVGFYSAFMVASKVEVITKKAAENTVWKWTSEGQNAYTLD
EVDAAAFPVLEGVAEGSAGTCVVLHLSQENSEFATRWRLEEVIKKYSDHIAFPIYLHYLQKEYDKDGAVTDTQKKVDQVN
DAGALWKRPKSELKEEDYHRFYQTLTRDSTPPLLYVHTKAEGTQEYVTLFYVPAKAPFDLFHADYKPGVKLFVKRVFITD
DEKELLPVYLRFVRGVIDSEDLPLNVSREILQQNRVLAAIKSASVKKLLGEFKRLAECDGKKYDEFITQYNRPLKEGLYS
DYEHREQLLELVRFRTLSESVPEDGWTSFAEYVSRMKPDQKAIYYIAGNDDRVLRQSPHAESYRLQGFEVLVMSDDIDGI
VMPSVSKYKEWELRAINRLGSEEELRPNEETDAAAQREQGFKPLLERLTHILSDSVKEVRLSKRLSDSVSCIVIDENDPT
VQMERLMRATGQTHKSKIKPILEINASHTLVQKLKESTDEAFVEDLAFVLLDQALLIEGMDVGSSVDFVKRVNRLLARG
>Mature_638_residues
AQYEFQTEVSQLLTLIIHSLYSHKEIFLRELISNASDALDKLKYEALVDGTYKQLHCEARIDIAFEEDAQRLVVRDTGIG
MNAEDLRANLGTIARSGTKAFLSTLTRDQKQDSNLIGQFGVGFYSAFMVASKVEVITKKAAENTVWKWTSEGQNAYTLDE
VDAAAFPVLEGVAEGSAGTCVVLHLSQENSEFATRWRLEEVIKKYSDHIAFPIYLHYLQKEYDKDGAVTDTQKKVDQVND
AGALWKRPKSELKEEDYHRFYQTLTRDSTPPLLYVHTKAEGTQEYVTLFYVPAKAPFDLFHADYKPGVKLFVKRVFITDD
EKELLPVYLRFVRGVIDSEDLPLNVSREILQQNRVLAAIKSASVKKLLGEFKRLAECDGKKYDEFITQYNRPLKEGLYSD
YEHREQLLELVRFRTLSESVPEDGWTSFAEYVSRMKPDQKAIYYIAGNDDRVLRQSPHAESYRLQGFEVLVMSDDIDGIV
MPSVSKYKEWELRAINRLGSEEELRPNEETDAAAQREQGFKPLLERLTHILSDSVKEVRLSKRLSDSVSCIVIDENDPTV
QMERLMRATGQTHKSKIKPILEINASHTLVQKLKESTDEAFVEDLAFVLLDQALLIEGMDVGSSVDFVKRVNRLLARG

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=691, Percent_Identity=37.0477568740955, Blast_Score=386, Evalue=1e-107,
Organism=Homo sapiens, GI154146191, Length=696, Percent_Identity=35.0574712643678, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI153792590, Length=696, Percent_Identity=35.0574712643678, Blast_Score=361, Evalue=1e-99,
Organism=Homo sapiens, GI155722983, Length=653, Percent_Identity=31.3935681470138, Blast_Score=316, Evalue=3e-86,
Organism=Homo sapiens, GI4507677, Length=217, Percent_Identity=44.7004608294931, Blast_Score=161, Evalue=1e-39,
Organism=Escherichia coli, GI1786679, Length=635, Percent_Identity=41.8897637795276, Blast_Score=489, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI17559162, Length=676, Percent_Identity=35.0591715976331, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17542208, Length=679, Percent_Identity=35.0515463917526, Blast_Score=357, Evalue=7e-99,
Organism=Caenorhabditis elegans, GI115535205, Length=653, Percent_Identity=32.0061255742726, Blast_Score=288, Evalue=7e-78,
Organism=Caenorhabditis elegans, GI115535167, Length=464, Percent_Identity=35.1293103448276, Blast_Score=236, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6323840, Length=688, Percent_Identity=36.046511627907, Blast_Score=408, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6325016, Length=692, Percent_Identity=35.5491329479769, Blast_Score=404, Evalue=1e-113,
Organism=Drosophila melanogaster, GI17647529, Length=692, Percent_Identity=35.1156069364162, Blast_Score=389, Evalue=1e-108,
Organism=Drosophila melanogaster, GI21357739, Length=690, Percent_Identity=33.768115942029, Blast_Score=341, Evalue=8e-94,
Organism=Drosophila melanogaster, GI24586016, Length=660, Percent_Identity=32.5757575757576, Blast_Score=302, Evalue=4e-82,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_TREPA (O83949)

Other databases:

- EMBL:   AE000520
- PIR:   F71258
- RefSeq:   NP_219421.1
- ProteinModelPortal:   O83949
- IntAct:   O83949
- GeneID:   2611612
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0984
- NMPDR:   fig|243276.1.peg.979
- TIGR:   TP_0984
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- BioCyc:   TPAL243276:TP_0984-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 72938; Mature: 72807

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQYEFQTEVSQLLTLIIHSLYSHKEIFLRELISNASDALDKLKYEALVDGTYKQLHCEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEE
RIDIAFEEDAQRLVVRDTGIGMNAEDLRANLGTIARSGTKAFLSTLTRDQKQDSNLIGQF
EEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHH
GVGFYSAFMVASKVEVITKKAAENTVWKWTSEGQNAYTLDEVDAAAFPVLEGVAEGSAGT
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEHHHHHHHHHHHHHHHCCCCCCE
CVVLHLSQENSEFATRWRLEEVIKKYSDHIAFPIYLHYLQKEYDKDGAVTDTQKKVDQVN
EEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
DAGALWKRPKSELKEEDYHRFYQTLTRDSTPPLLYVHTKAEGTQEYVTLFYVPAKAPFDL
CCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEECCCCCHHH
FHADYKPGVKLFVKRVFITDDEKELLPVYLRFVRGVIDSEDLPLNVSREILQQNRVLAAI
HHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
KSASVKKLLGEFKRLAECDGKKYDEFITQYNRPLKEGLYSDYEHREQLLELVRFRTLSES
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHC
VPEDGWTSFAEYVSRMKPDQKAIYYIAGNDDRVLRQSPHAESYRLQGFEVLVMSDDIDGI
CCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHCCCCCCCEEECCEEEEEEECCCCCE
VMPSVSKYKEWELRAINRLGSEEELRPNEETDAAAQREQGFKPLLERLTHILSDSVKEVR
ECCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LSKRLSDSVSCIVIDENDPTVQMERLMRATGQTHKSKIKPILEINASHTLVQKLKESTDE
HHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHCCCCEEECCHHHHHHHHHHHHHH
AFVEDLAFVLLDQALLIEGMDVGSSVDFVKRVNRLLARG
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQYEFQTEVSQLLTLIIHSLYSHKEIFLRELISNASDALDKLKYEALVDGTYKQLHCEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEE
RIDIAFEEDAQRLVVRDTGIGMNAEDLRANLGTIARSGTKAFLSTLTRDQKQDSNLIGQF
EEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHH
GVGFYSAFMVASKVEVITKKAAENTVWKWTSEGQNAYTLDEVDAAAFPVLEGVAEGSAGT
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEHHHHHHHHHHHHHHHCCCCCCE
CVVLHLSQENSEFATRWRLEEVIKKYSDHIAFPIYLHYLQKEYDKDGAVTDTQKKVDQVN
EEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
DAGALWKRPKSELKEEDYHRFYQTLTRDSTPPLLYVHTKAEGTQEYVTLFYVPAKAPFDL
CCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEECCCCCHHH
FHADYKPGVKLFVKRVFITDDEKELLPVYLRFVRGVIDSEDLPLNVSREILQQNRVLAAI
HHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
KSASVKKLLGEFKRLAECDGKKYDEFITQYNRPLKEGLYSDYEHREQLLELVRFRTLSES
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHC
VPEDGWTSFAEYVSRMKPDQKAIYYIAGNDDRVLRQSPHAESYRLQGFEVLVMSDDIDGI
CCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHCCCCCCCEEECCEEEEEEECCCCCE
VMPSVSKYKEWELRAINRLGSEEELRPNEETDAAAQREQGFKPLLERLTHILSDSVKEVR
ECCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LSKRLSDSVSCIVIDENDPTVQMERLMRATGQTHKSKIKPILEINASHTLVQKLKESTDE
HHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHCCCCEEECCHHHHHHHHHHHHHH
AFVEDLAFVLLDQALLIEGMDVGSSVDFVKRVNRLLARG
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876