| Definition | Treponema pallidum subsp. pallidum SS14, complete genome. |
|---|---|
| Accession | NC_010741 |
| Length | 1,139,457 |
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The map label for this gene is ppdK [H]
Identifier: 189025971
GI number: 189025971
Start: 810518
End: 813223
Strand: Reverse
Name: ppdK [H]
Synonym: TPASS_0746
Alternate gene names: 189025971
Gene position: 813223-810518 (Counterclockwise)
Preceding gene: 189025972
Following gene: 189025970
Centisome position: 71.37
GC content: 51.07
Gene sequence:
>2706_bases ATGAACATTGCCAAATCCATTCATTTTCTGAGCAATAAAGAGGCTCTCGATAAGAGGCTTGACCGAGGGCTTTTGGGGAT TCGGGGTCGTCAGGCGGATGAGTTGTCAAGTCTGGGGTTGCCCGTGCTTCCGAGCGTGGTTATTGATGCGACAGTCTCTC GTAGTCTGTATGGGGAGAAGCTTCGGTCCGCGCTAAGTCCGTATTTAAGGAAGTTTACGCTTTTAAACAGAAAAGAGTAT GCGGATGCAAAGAATCCTATGCTCCTCAAGGTGGTTTTATCCCCCAATTTGGCCATTTCGAATTATCCGGTATTACATAA CTTTGGTTTGACACGGGATACTTTCGCGGGGTTTGCCGAGCGTGTCGGGGAGCATTTTGCAACGCACGAGGTGTTCTTCC TTTTGAAGGGTGTATTTGGGGTATTGCTTGGTATCGCAGAAAGTGAGGAGAACACCAAGGGTGCTTCGGAGTTTGTCGAA ACCCTGAAGGAAATAGAGGTTTTTTTGCAGGGAGGAAAATCTTCTCCCTCTGGGCGCGAGGCGATGAATCGGTATCGAGC CTTGCTTCCAGACGGCTTTTTCGATGATGCCTACGTTCAGCTTGAAGAAGCGGTAAGGCTTGTTAGTAAACTGCTGTCGT TTGAGGAGGATGGGGAAGATGGAGTTGCCATCCTTATTCAGCCTATGGTCTACGGGAATTATGGGGGAGGCAGCTACTCG GGTCGGTTTTTCAGTAGGAATATTATAACTGGAGAGAAGAAACTTCAGGGTCAGTATTTTGAGGAGCGGTTCGACGAATG CGATGCCGAAGGCAGTGATGTAAATGCGATAAAGCCGGCTTATCTTAAGCAGTTGCAGGATATTGCGTGGAAACTGGAGG ATCACAGCCGAGAGATTCGGGAGGTTCGCTTTACTATCGAGGCGGGCAGTTTATGGCTTATTGAGCAAAAACCTGTCGAA GCGAAGAGCACAATCTCTTTGGTACGGTTGCTGCTCGACCTGTACGAGCGCGAGGTGGTGGATGCTGAATACGTGGTCAA GTCGGTAAAACCGGGTCAGCTGAACGAGATTTTGCACCCGGTCATTGATATGACGAGTGTGACAGGTTTGAAATCCTCGC AGGGGGGGATTATTGGTGCTCCTGGTGCGGCGGTTGGGCGAGTGTACTTTACCGCTGATTCCCTCATCGAGGCGTGGCGT GTGGCGAAGATGGGCGGACAAGATACACGGTGTATCTTGTGTATGCCTGCAACGTACGCGGGGGACGTTAAGGCAATTGA GGTGGCAACTGGTGTTCTTTCTAACGAGGGGGGGTACTCCGCCCACGCTTCGGTTGTTGCCCGTCAGTATGGGAAGATCT CTTTGGTCCGTCCAGATATGAAGATTTATTCGGACAAAGCGGTCGTTGACGGTATGACTATCAACGAGGGCGATTTTGTA ACGCTTAATGTTCCTTACTACGGGGAATCCACCCTGTATATGGGAGCTGCGCAGCTCATTGAGCCTGATCCAGAGACGTC TGGCCTAGTGAGCTTCATCGAGCTTGCGAAGGGTTTTGTGCGTTCGTTTCACGTGCGGGCGAACGCGGACAGTCCACACG ATGCAGAGCTCGCGCTCGCCTTTGGTGCGCAGGGTATCGGACTGTGTCGTACAGAGCATATGTTCTTCAAAGAAGATCGG ATAAATGTGTTCCGCCGTATGATCTTCTCGGAGAATGCTGAGGAGCGGACGGGCAGTCTCAAGCAGTTGCAAAAGATGCA GGGAGAGGATTTCTACGGCATCTTCAAGGTAATGCAGGGACATGAAGTGACTATTCGCCTTCTGGATGCTCCTTTGCACG AGTTTTTGCCGCACGGGGAGAGTGAAGTTAGCAAGTTTTTGGAGTATCTCGAGAAGGTTTGTGGTAAAGGTCTGTCCCGG GAGGAGTTGCAGGAGCGGATCTCCATGCTATCTGAGGTGAATCCCATGCTGGGTCACCGTGGGTGCCGTATTGCGATTTC ATACCCGGAAATCTACGCCATGCAGGTGCGCGCCGTGTTCGAGGCAGTGTACCGGTTGCAGAAAGAGAAGATCTCGGTGT ACCCAGAGATAATGATCCCCATTGTCATGAATTGCCGTGAGTTAAAGCAGATTGTGTATGGTAAAAAGATTGAGGGGCAC GCATACCAGGGTATCGGCTCGATAGAGGAAGAGGTACGTCTTGCGCTCAAGGCAAAGGAGGTTGACTATAAGGTGGGTGC TATGATTGAGCTGCCTGCAGCTGCGTTGAGTGCAGACGAGATTGCGCGCTACGCGCAGTTTTTCTCGTTTGGGACTAATG ACTTGACGCAGACAACGCTTGGACTCTCCAGAGACGATTTCAATACGTTTATGCCGGACTACACGATGTATGATTTGGTT GACGGAAACCCCTTTGCGATACTCGATGCGCGCGTGCGCGAGTTAATTGAGGTTGCTATGCAGCGTGGACGGCTGGCACG GCCGGATATTCAGCTAGGTTTGTGTGGGGAGCACGGTTCACGGTCAGAAAATATTCGTTTTTGTATGGAAGTAGGACTAG ATTACGTTTCGTGTTCGTCTTACTCGGTGCCTATCGCTTTACTTGCAATTGCACAGGCGGAGATTGAAAACGCAGAAAAG GAAGGCAGGAAGCCTGCATGGCGGGGAAGGTCTTCCGCGAAGTCAGGCGGTAGGCGCGCTAGGTAA
Upstream 100 bases:
>100_bases CAAGCTCTCTAAGTATTTCAAGGAGGGGGCGAGTTCTCGTTTTGAGGTGTTTTTGCACGGTTCCCCAGACACGGTGTTGA ATTTGTTTTAGGAGTGCACA
Downstream 100 bases:
>100_bases GGTGTCGTTCGTGCTTGGTGAGCGTCTCTGTGCGTTCCACTAACGGTGCGAGGGATGGCTGCGTCTGCGTGGTTAGAGGT GTAGCTGGGTGTTTTTTGGA
Product: pyruvate phosphate dikinase
Products: NA
Alternate protein names: Pyruvate, orthophosphate dikinase [H]
Number of amino acids: Translated: 901; Mature: 901
Protein sequence:
>901_residues MNIAKSIHFLSNKEALDKRLDRGLLGIRGRQADELSSLGLPVLPSVVIDATVSRSLYGEKLRSALSPYLRKFTLLNRKEY ADAKNPMLLKVVLSPNLAISNYPVLHNFGLTRDTFAGFAERVGEHFATHEVFFLLKGVFGVLLGIAESEENTKGASEFVE TLKEIEVFLQGGKSSPSGREAMNRYRALLPDGFFDDAYVQLEEAVRLVSKLLSFEEDGEDGVAILIQPMVYGNYGGGSYS GRFFSRNIITGEKKLQGQYFEERFDECDAEGSDVNAIKPAYLKQLQDIAWKLEDHSREIREVRFTIEAGSLWLIEQKPVE AKSTISLVRLLLDLYEREVVDAEYVVKSVKPGQLNEILHPVIDMTSVTGLKSSQGGIIGAPGAAVGRVYFTADSLIEAWR VAKMGGQDTRCILCMPATYAGDVKAIEVATGVLSNEGGYSAHASVVARQYGKISLVRPDMKIYSDKAVVDGMTINEGDFV TLNVPYYGESTLYMGAAQLIEPDPETSGLVSFIELAKGFVRSFHVRANADSPHDAELALAFGAQGIGLCRTEHMFFKEDR INVFRRMIFSENAEERTGSLKQLQKMQGEDFYGIFKVMQGHEVTIRLLDAPLHEFLPHGESEVSKFLEYLEKVCGKGLSR EELQERISMLSEVNPMLGHRGCRIAISYPEIYAMQVRAVFEAVYRLQKEKISVYPEIMIPIVMNCRELKQIVYGKKIEGH AYQGIGSIEEEVRLALKAKEVDYKVGAMIELPAAALSADEIARYAQFFSFGTNDLTQTTLGLSRDDFNTFMPDYTMYDLV DGNPFAILDARVRELIEVAMQRGRLARPDIQLGLCGEHGSRSENIRFCMEVGLDYVSCSSYSVPIALLAIAQAEIENAEK EGRKPAWRGRSSAKSGGRRAR
Sequences:
>Translated_901_residues MNIAKSIHFLSNKEALDKRLDRGLLGIRGRQADELSSLGLPVLPSVVIDATVSRSLYGEKLRSALSPYLRKFTLLNRKEY ADAKNPMLLKVVLSPNLAISNYPVLHNFGLTRDTFAGFAERVGEHFATHEVFFLLKGVFGVLLGIAESEENTKGASEFVE TLKEIEVFLQGGKSSPSGREAMNRYRALLPDGFFDDAYVQLEEAVRLVSKLLSFEEDGEDGVAILIQPMVYGNYGGGSYS GRFFSRNIITGEKKLQGQYFEERFDECDAEGSDVNAIKPAYLKQLQDIAWKLEDHSREIREVRFTIEAGSLWLIEQKPVE AKSTISLVRLLLDLYEREVVDAEYVVKSVKPGQLNEILHPVIDMTSVTGLKSSQGGIIGAPGAAVGRVYFTADSLIEAWR VAKMGGQDTRCILCMPATYAGDVKAIEVATGVLSNEGGYSAHASVVARQYGKISLVRPDMKIYSDKAVVDGMTINEGDFV TLNVPYYGESTLYMGAAQLIEPDPETSGLVSFIELAKGFVRSFHVRANADSPHDAELALAFGAQGIGLCRTEHMFFKEDR INVFRRMIFSENAEERTGSLKQLQKMQGEDFYGIFKVMQGHEVTIRLLDAPLHEFLPHGESEVSKFLEYLEKVCGKGLSR EELQERISMLSEVNPMLGHRGCRIAISYPEIYAMQVRAVFEAVYRLQKEKISVYPEIMIPIVMNCRELKQIVYGKKIEGH AYQGIGSIEEEVRLALKAKEVDYKVGAMIELPAAALSADEIARYAQFFSFGTNDLTQTTLGLSRDDFNTFMPDYTMYDLV DGNPFAILDARVRELIEVAMQRGRLARPDIQLGLCGEHGSRSENIRFCMEVGLDYVSCSSYSVPIALLAIAQAEIENAEK EGRKPAWRGRSSAKSGGRRAR >Mature_901_residues MNIAKSIHFLSNKEALDKRLDRGLLGIRGRQADELSSLGLPVLPSVVIDATVSRSLYGEKLRSALSPYLRKFTLLNRKEY ADAKNPMLLKVVLSPNLAISNYPVLHNFGLTRDTFAGFAERVGEHFATHEVFFLLKGVFGVLLGIAESEENTKGASEFVE TLKEIEVFLQGGKSSPSGREAMNRYRALLPDGFFDDAYVQLEEAVRLVSKLLSFEEDGEDGVAILIQPMVYGNYGGGSYS GRFFSRNIITGEKKLQGQYFEERFDECDAEGSDVNAIKPAYLKQLQDIAWKLEDHSREIREVRFTIEAGSLWLIEQKPVE AKSTISLVRLLLDLYEREVVDAEYVVKSVKPGQLNEILHPVIDMTSVTGLKSSQGGIIGAPGAAVGRVYFTADSLIEAWR VAKMGGQDTRCILCMPATYAGDVKAIEVATGVLSNEGGYSAHASVVARQYGKISLVRPDMKIYSDKAVVDGMTINEGDFV TLNVPYYGESTLYMGAAQLIEPDPETSGLVSFIELAKGFVRSFHVRANADSPHDAELALAFGAQGIGLCRTEHMFFKEDR INVFRRMIFSENAEERTGSLKQLQKMQGEDFYGIFKVMQGHEVTIRLLDAPLHEFLPHGESEVSKFLEYLEKVCGKGLSR EELQERISMLSEVNPMLGHRGCRIAISYPEIYAMQVRAVFEAVYRLQKEKISVYPEIMIPIVMNCRELKQIVYGKKIEGH AYQGIGSIEEEVRLALKAKEVDYKVGAMIELPAAALSADEIARYAQFFSFGTNDLTQTTLGLSRDDFNTFMPDYTMYDLV DGNPFAILDARVRELIEVAMQRGRLARPDIQLGLCGEHGSRSENIRFCMEVGLDYVSCSSYSVPIALLAIAQAEIENAEK EGRKPAWRGRSSAKSGGRRAR
Specific function: Catalyzes the reversible phosphorylation of pyruvate and phosphate [H]
COG id: COG0574
COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the PEP-utilizing enzyme family [H]
Homologues:
Organism=Escherichia coli, GI1788756, Length=444, Percent_Identity=24.5495495495495, Blast_Score=87, Evalue=7e-18, Organism=Escherichia coli, GI1787994, Length=462, Percent_Identity=25.7575757575758, Blast_Score=86, Evalue=1e-17, Organism=Escherichia coli, GI48994992, Length=469, Percent_Identity=23.0277185501066, Blast_Score=75, Evalue=3e-14, Organism=Escherichia coli, GI1788726, Length=371, Percent_Identity=22.911051212938, Blast_Score=70, Evalue=8e-13,
Paralogues:
None
Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2659 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013816 - InterPro: IPR008279 - InterPro: IPR018274 - InterPro: IPR023151 - InterPro: IPR000121 - InterPro: IPR002192 - InterPro: IPR010121 - InterPro: IPR015813 [H]
Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]
EC number: =2.7.9.1 [H]
Molecular weight: Translated: 100271; Mature: 100271
Theoretical pI: Translated: 5.48; Mature: 5.48
Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNIAKSIHFLSNKEALDKRLDRGLLGIRGRQADELSSLGLPVLPSVVIDATVSRSLYGEK CCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHH LRSALSPYLRKFTLLNRKEYADAKNPMLLKVVLSPNLAISNYPVLHNFGLTRDTFAGFAE HHHHHHHHHHHHHHHCCHHHCCCCCCEEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHH RVGEHFATHEVFFLLKGVFGVLLGIAESEENTKGASEFVETLKEIEVFLQGGKSSPSGRE HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHH AMNRYRALLPDGFFDDAYVQLEEAVRLVSKLLSFEEDGEDGVAILIQPMVYGNYGGGSYS HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCCCC GRFFSRNIITGEKKLQGQYFEERFDECDAEGSDVNAIKPAYLKQLQDIAWKLEDHSREIR CCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH EVRFTIEAGSLWLIEQKPVEAKSTISLVRLLLDLYEREVVDAEYVVKSVKPGQLNEILHP HEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHH VIDMTSVTGLKSSQGGIIGAPGAAVGRVYFTADSLIEAWRVAKMGGQDTRCILCMPATYA HHHHHHHCCCCCCCCCEEECCCHHHCEEEEEHHHHHHHHHHHHCCCCCCEEEEEECCCCC GDVKAIEVATGVLSNEGGYSAHASVVARQYGKISLVRPDMKIYSDKAVVDGMTINEGDFV CCCEEEEHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCCHHHHCCCHHCCCEEECCCCEE TLNVPYYGESTLYMGAAQLIEPDPETSGLVSFIELAKGFVRSFHVRANADSPHDAELALA EEECCCCCCCHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEEE FGAQGIGLCRTEHMFFKEDRINVFRRMIFSENAEERTGSLKQLQKMQGEDFYGIFKVMQG ECCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHCCCCHHHHHHHHCC HEVTIRLLDAPLHEFLPHGESEVSKFLEYLEKVCGKGLSREELQERISMLSEVNPMLGHR CCEEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHCCC GCRIAISYPEIYAMQVRAVFEAVYRLQKEKISVYPEIMIPIVMNCRELKQIVYGKKIEGH CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHCCCCCCCC AYQGIGSIEEEVRLALKAKEVDYKVGAMIELPAAALSADEIARYAQFFSFGTNDLTQTTL HHCCCCHHHHHHHHHHHHHHCCEECCCEEECCHHHCCHHHHHHHHHHHHCCCCHHHHHHH GLSRDDFNTFMPDYTMYDLVDGNPFAILDARVRELIEVAMQRGRLARPDIQLGLCGEHGS CCCCCCHHHHCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCC RSENIRFCMEVGLDYVSCSSYSVPIALLAIAQAEIENAEKEGRKPAWRGRSSAKSGGRRA CCCHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC R C >Mature Secondary Structure MNIAKSIHFLSNKEALDKRLDRGLLGIRGRQADELSSLGLPVLPSVVIDATVSRSLYGEK CCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHH LRSALSPYLRKFTLLNRKEYADAKNPMLLKVVLSPNLAISNYPVLHNFGLTRDTFAGFAE HHHHHHHHHHHHHHHCCHHHCCCCCCEEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHH RVGEHFATHEVFFLLKGVFGVLLGIAESEENTKGASEFVETLKEIEVFLQGGKSSPSGRE HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHH AMNRYRALLPDGFFDDAYVQLEEAVRLVSKLLSFEEDGEDGVAILIQPMVYGNYGGGSYS HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCCCC GRFFSRNIITGEKKLQGQYFEERFDECDAEGSDVNAIKPAYLKQLQDIAWKLEDHSREIR CCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH EVRFTIEAGSLWLIEQKPVEAKSTISLVRLLLDLYEREVVDAEYVVKSVKPGQLNEILHP HEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHH VIDMTSVTGLKSSQGGIIGAPGAAVGRVYFTADSLIEAWRVAKMGGQDTRCILCMPATYA HHHHHHHCCCCCCCCCEEECCCHHHCEEEEEHHHHHHHHHHHHCCCCCCEEEEEECCCCC GDVKAIEVATGVLSNEGGYSAHASVVARQYGKISLVRPDMKIYSDKAVVDGMTINEGDFV CCCEEEEHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCCHHHHCCCHHCCCEEECCCCEE TLNVPYYGESTLYMGAAQLIEPDPETSGLVSFIELAKGFVRSFHVRANADSPHDAELALA EEECCCCCCCHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEEE FGAQGIGLCRTEHMFFKEDRINVFRRMIFSENAEERTGSLKQLQKMQGEDFYGIFKVMQG ECCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHCCCCHHHHHHHHCC HEVTIRLLDAPLHEFLPHGESEVSKFLEYLEKVCGKGLSREELQERISMLSEVNPMLGHR CCEEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHCCC GCRIAISYPEIYAMQVRAVFEAVYRLQKEKISVYPEIMIPIVMNCRELKQIVYGKKIEGH CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHCCCCCCCC AYQGIGSIEEEVRLALKAKEVDYKVGAMIELPAAALSADEIARYAQFFSFGTNDLTQTTL HHCCCCHHHHHHHHHHHHHHCCEECCCEEECCHHHCCHHHHHHHHHHHHCCCCHHHHHHH GLSRDDFNTFMPDYTMYDLVDGNPFAILDARVRELIEVAMQRGRLARPDIQLGLCGEHGS CCCCCCHHHHCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCC RSENIRFCMEVGLDYVSCSSYSVPIALLAIAQAEIENAEKEGRKPAWRGRSSAKSGGRRA CCCHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC R C
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9665876 [H]