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The map label for this gene is troC

Identifier: 189025398

GI number: 189025398

Start: 187640

End: 188536

Strand: Direct

Name: troC

Synonym: TPASS_0165

Alternate gene names: 189025398

Gene position: 187640-188536 (Clockwise)

Preceding gene: 189025397

Following gene: 189025399

Centisome position: 16.47

GC content: 51.62

Gene sequence:

>897_bases
ATGCACGCGCTCATGCGTCTGTTCTCTGACTATACGCTGCAAAATGTGGTGTTAGGCACGCTTTTTTTGGGTTTGGGTTC
TGGGCTGGTCGGCAGTTTTGCGGTGCTGCGTCGACAAAGCCTTTTCGGTGACGCAGTTTCTCATGCAACCCTTCCGGGGA
TTGTTATCGCGTTTCTTTTAACCGGCACGAAGTCTACTGAGATACTTTTGCTGGGTGCTGCCCTCAGTGGTTTAGTAGGA
ACTGTGGTGATGCTAATGGTGATGCGTACTACAAAAATTGATACCGATGGTGCGCAGGGCATTGTGTTGGGTGTTTTTCT
TGGGTTTGGGTTTCTATTACTCACCCACGTGCAGAAGTCGCCCCAGGCGGCAAAGGCTGGTCTGAACAAATTCATTCTAG
GGCAAGCGGCCACGATTTTGCAGCGAGATGTCCTGCTCATCATTGCGATGGAGGTGGTGATCGGTTTGCTTGTACTGCTG
TTTTGGAAAGAACTGAAGCTTTCTACCTTCGATCGAGACTTCTCTGCGGTGCAAGGTTTTTCTCCACAGCTTATGGAGTT
CATGCTCACGGCACTCATCGTAGTTGCAGTTGTCGTAGGGGTTCAGGCAGTGGGGGTTATCTTGATGAGCGCACTGCTGA
CTGCGCCTGCAGTGGCAGCGCGGCAGTGGACAAACAGTTTAAGGGTTTTATGCGCGCTTGCTGCTTTATTTGGGGGTGTC
TCAGGTGTTTCAGGTTCGGTTGTCTCTGCCCAGGTTCCCAGGCTTTCTACTGGCCCCGTGATAGTGTTGGTGCTGACGGG
TATTGCGCTTGTCTCTATTATGCTTGGTCCTCAGCGGGGTGTTTTGTATCAACTGTGGCGGAGAAGACGGGTTTCGCTTC
TTCAAGAGGAGGGGTAG

Upstream 100 bases:

>100_bases
GCCGTCGTGTCTGCCTTCACCGAAGAATACGTTCAAAGAGCCTATGGCGGACGGATTAGTTCCACCCTTTTTCCGAGAGG
AAATAAGGAGGATGTGCACG

Downstream 100 bases:

>100_bases
AATATGACCATGGAGGTTGTGCTTATTGCAGTGGTCGTGTCGGTTGCGTGCGCGCTGTGTGGGGTTTTCTTAGTGTTGCG
TAGAATATCGCTGATGAGTG

Product: ABC transporter, permease protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MHALMRLFSDYTLQNVVLGTLFLGLGSGLVGSFAVLRRQSLFGDAVSHATLPGIVIAFLLTGTKSTEILLLGAALSGLVG
TVVMLMVMRTTKIDTDGAQGIVLGVFLGFGFLLLTHVQKSPQAAKAGLNKFILGQAATILQRDVLLIIAMEVVIGLLVLL
FWKELKLSTFDRDFSAVQGFSPQLMEFMLTALIVVAVVVGVQAVGVILMSALLTAPAVAARQWTNSLRVLCALAALFGGV
SGVSGSVVSAQVPRLSTGPVIVLVLTGIALVSIMLGPQRGVLYQLWRRRRVSLLQEEG

Sequences:

>Translated_298_residues
MHALMRLFSDYTLQNVVLGTLFLGLGSGLVGSFAVLRRQSLFGDAVSHATLPGIVIAFLLTGTKSTEILLLGAALSGLVG
TVVMLMVMRTTKIDTDGAQGIVLGVFLGFGFLLLTHVQKSPQAAKAGLNKFILGQAATILQRDVLLIIAMEVVIGLLVLL
FWKELKLSTFDRDFSAVQGFSPQLMEFMLTALIVVAVVVGVQAVGVILMSALLTAPAVAARQWTNSLRVLCALAALFGGV
SGVSGSVVSAQVPRLSTGPVIVLVLTGIALVSIMLGPQRGVLYQLWRRRRVSLLQEEG
>Mature_298_residues
MHALMRLFSDYTLQNVVLGTLFLGLGSGLVGSFAVLRRQSLFGDAVSHATLPGIVIAFLLTGTKSTEILLLGAALSGLVG
TVVMLMVMRTTKIDTDGAQGIVLGVFLGFGFLLLTHVQKSPQAAKAGLNKFILGQAATILQRDVLLIIAMEVVIGLLVLL
FWKELKLSTFDRDFSAVQGFSPQLMEFMLTALIVVAVVVGVQAVGVILMSALLTAPAVAARQWTNSLRVLCALAALFGGV
SGVSGSVVSAQVPRLSTGPVIVLVLTGIALVSIMLGPQRGVLYQLWRRRRVSLLQEEG

Specific function: Part of an ATP-driven transport system troABCD for zinc

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family

Homologues:

Organism=Escherichia coli, GI1788166, Length=258, Percent_Identity=26.3565891472868, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TROC_TREPA (P96118)

Other databases:

- EMBL:   U55214
- EMBL:   AE000520
- PIR:   B71357
- RefSeq:   NP_218604.1
- ProteinModelPortal:   P96118
- IntAct:   P96118
- GeneID:   2611129
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0165
- NMPDR:   fig|243276.1.peg.163
- TIGR:   TP_0165
- HOGENOM:   HBG733179
- OMA:   GSTAGML
- ProtClustDB:   CLSK873795
- BioCyc:   TPAL243276:TP_0165-MONOMER
- InterPro:   IPR001626

Pfam domain/function: PF00950 ABC-3

EC number: NA

Molecular weight: Translated: 31540; Mature: 31540

Theoretical pI: Translated: 10.91; Mature: 10.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1fd65f08)-; HASH(0x20751e18)-; HASH(0x1f6e338c)-; HASH(0x205c7bd0)-; HASH(0x1fec0640)-; HASH(0x1fee02a0)-; HASH(0x20748ed4)-; HASH(0x2007cdb8)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHALMRLFSDYTLQNVVLGTLFLGLGSGLVGSFAVLRRQSLFGDAVSHATLPGIVIAFLL
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGTKSTEILLLGAALSGLVGTVVMLMVMRTTKIDTDGAQGIVLGVFLGFGFLLLTHVQKS
CCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
PQAAKAGLNKFILGQAATILQRDVLLIIAMEVVIGLLVLLFWKELKLSTFDRDFSAVQGF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
SPQLMEFMLTALIVVAVVVGVQAVGVILMSALLTAPAVAARQWTNSLRVLCALAALFGGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SGVSGSVVSAQVPRLSTGPVIVLVLTGIALVSIMLGPQRGVLYQLWRRRRVSLLQEEG
CCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MHALMRLFSDYTLQNVVLGTLFLGLGSGLVGSFAVLRRQSLFGDAVSHATLPGIVIAFLL
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGTKSTEILLLGAALSGLVGTVVMLMVMRTTKIDTDGAQGIVLGVFLGFGFLLLTHVQKS
CCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
PQAAKAGLNKFILGQAATILQRDVLLIIAMEVVIGLLVLLFWKELKLSTFDRDFSAVQGF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
SPQLMEFMLTALIVVAVVVGVQAVGVILMSALLTAPAVAARQWTNSLRVLCALAALFGGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SGVSGSVVSAQVPRLSTGPVIVLVLTGIALVSIMLGPQRGVLYQLWRRRRVSLLQEEG
CCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9332349; 9665876