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The map label for this gene is lytT [H]

Identifier: 188586538

GI number: 188586538

Start: 2022357

End: 2023109

Strand: Reverse

Name: lytT [H]

Synonym: Nther_1924

Alternate gene names: 188586538

Gene position: 2023109-2022357 (Counterclockwise)

Preceding gene: 188586540

Following gene: 188586537

Centisome position: 63.91

GC content: 31.87

Gene sequence:

>753_bases
ATGGGTGGTGTGGTTGTTTTAATTTTAGAAGATGAACCTTATACCAAAAAATATGTCAAAAACTTGGTTTCTCAAAATAA
AATGGTTAAAGAAATTTATGACACAGAAAGCTCTAGAGAGGCTGTCGAAATGGCGGAAAAAGTGCAGCCTGATATTGCTT
TAATTGACATTGAGTTGACGGATCAAAGAATGAACGGCTTAGAGACTGCACAATTAATCAAACAAGTCAATCCGGAAATA
GAATTTATATTTGTTACAGCTTATTCTGAATACGCTTTGCAGTCTTTCTCTGTACATCCCTTTGATTACCTGGTTAAACC
AATTGATGAGGATAAGCTATTAAATTCGATTAAGATGCTTATAGAGCGATTAAATTTAAATAGGAATGGTAGTGAATCTA
ACAAAGAAGCTAATGCACGTTTAATAATTGAAGAACCTAAGAAGATGTTGTTTATTCCTCTTGAAAATATTCTATTTTTG
GAAAAACAAAAAAACAAAAATCAAGTGTTGATTCACATACAAGATGGGAAAATTTATGAAACGACTAAGAGATTAAGTGA
CTTAGAAGAAGAATTGACGGATAGCTTTGTCAGAACACACAGATCGTATATTGTTAATGTAAATAAAGTACTTAAGGTTA
TGGAGATTTACGATCGATCTTATGAGATAGAGTTTAGAGAAAGTAACAAAAAAGCTCTTTTAAGTCGATATAAGCTAGAA
GAATTTCAAGAACAAGTAGCAATAGACTCCTAG

Upstream 100 bases:

>100_bases
GGTGAAATAAAACTATTTTAGATTGGTTGAAAGTTTTGAGTGAACGAAGATTATATTTTTAAATTTATGTTTTAAGTATT
ATTAAAAGGCGAGTGATAAC

Downstream 100 bases:

>100_bases
AATGGACATAATAGATACATACTTTATATTAGAATAAGGGTTGCCCAGGAATTTTTGGGCAACCCTTATTTGTTGTGCGC
CATGCATGACGATTAGCTAG

Product: two component transcriptional regulator, LytTR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MGGVVVLILEDEPYTKKYVKNLVSQNKMVKEIYDTESSREAVEMAEKVQPDIALIDIELTDQRMNGLETAQLIKQVNPEI
EFIFVTAYSEYALQSFSVHPFDYLVKPIDEDKLLNSIKMLIERLNLNRNGSESNKEANARLIIEEPKKMLFIPLENILFL
EKQKNKNQVLIHIQDGKIYETTKRLSDLEEELTDSFVRTHRSYIVNVNKVLKVMEIYDRSYEIEFRESNKKALLSRYKLE
EFQEQVAIDS

Sequences:

>Translated_250_residues
MGGVVVLILEDEPYTKKYVKNLVSQNKMVKEIYDTESSREAVEMAEKVQPDIALIDIELTDQRMNGLETAQLIKQVNPEI
EFIFVTAYSEYALQSFSVHPFDYLVKPIDEDKLLNSIKMLIERLNLNRNGSESNKEANARLIIEEPKKMLFIPLENILFL
EKQKNKNQVLIHIQDGKIYETTKRLSDLEEELTDSFVRTHRSYIVNVNKVLKVMEIYDRSYEIEFRESNKKALLSRYKLE
EFQEQVAIDS
>Mature_249_residues
GGVVVLILEDEPYTKKYVKNLVSQNKMVKEIYDTESSREAVEMAEKVQPDIALIDIELTDQRMNGLETAQLIKQVNPEIE
FIFVTAYSEYALQSFSVHPFDYLVKPIDEDKLLNSIKMLIERLNLNRNGSESNKEANARLIIEEPKKMLFIPLENILFLE
KQKNKNQVLIHIQDGKIYETTKRLSDLEEELTDSFVRTHRSYIVNVNKVLKVMEIYDRSYEIEFRESNKKALLSRYKLEE
FQEQVAIDS

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=205, Percent_Identity=27.3170731707317, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788724, Length=243, Percent_Identity=20.5761316872428, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 29275; Mature: 29144

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGVVVLILEDEPYTKKYVKNLVSQNKMVKEIYDTESSREAVEMAEKVQPDIALIDIELT
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEEC
DQRMNGLETAQLIKQVNPEIEFIFVTAYSEYALQSFSVHPFDYLVKPIDEDKLLNSIKML
CHHHCCHHHHHHHHHCCCCEEEEEEEEEHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHH
IERLNLNRNGSESNKEANARLIIEEPKKMLFIPLENILFLEKQKNKNQVLIHIQDGKIYE
HHHHCCCCCCCCCCCCCCCEEEEECCCEEEEEEHHHEEEEECCCCCCEEEEEEECCCCHH
TTKRLSDLEEELTDSFVRTHRSYIVNVNKVLKVMEIYDRSYEIEFRESNKKALLSRYKLE
HHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHH
EFQEQVAIDS
HHHHHHCCCC
>Mature Secondary Structure 
GGVVVLILEDEPYTKKYVKNLVSQNKMVKEIYDTESSREAVEMAEKVQPDIALIDIELT
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEEC
DQRMNGLETAQLIKQVNPEIEFIFVTAYSEYALQSFSVHPFDYLVKPIDEDKLLNSIKML
CHHHCCHHHHHHHHHCCCCEEEEEEEEEHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHH
IERLNLNRNGSESNKEANARLIIEEPKKMLFIPLENILFLEKQKNKNQVLIHIQDGKIYE
HHHHCCCCCCCCCCCCCCCEEEEECCCEEEEEEHHHEEEEECCCCCCEEEEEEECCCCHH
TTKRLSDLEEELTDSFVRTHRSYIVNVNKVLKVMEIYDRSYEIEFRESNKKALLSRYKLE
HHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHH
EFQEQVAIDS
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]