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The map label for this gene is cutA [H]

Identifier: 188586513

GI number: 188586513

Start: 1992614

End: 1992934

Strand: Reverse

Name: cutA [H]

Synonym: Nther_1899

Alternate gene names: 188586513

Gene position: 1992934-1992614 (Counterclockwise)

Preceding gene: 188586514

Following gene: 188586512

Centisome position: 62.96

GC content: 36.14

Gene sequence:

>321_bases
ATGAGTAGATCAATGTTTTACATTACTGCTGAAAGTATGGAGGATGCTGAGCAACTCGCAAAACAACTTGTGGAAGATCG
TTTGGTAGCTTGTGTAAATGTAATACCTAAAATTAAATCTTTCTTCTATTGGGAAGGAGAGGCCCAATCCGAGGAAGAAG
TTTTATTATTCGGAAAAACTAAAACTGAAACAGTCAGCAAGTTAGTAGAAAGAGTTAAGGAACTCCATCCTTACGATGTA
CCTTGTGTAGTTACTTGGGAAATGAAAGATGGTAATCCGGATTTTCTAAAATGGATTGATGATGAAGTGAATCAATGCTA
A

Upstream 100 bases:

>100_bases
TAGCAATGCAAGCTGTAAAGCTAGCTATTGAGAAAGATGATTCGGGGATTTAATATAAATATTGATAATATATAGAAACT
TGGTAATAGGAGGGATAAGG

Downstream 100 bases:

>100_bases
AACAAAATGGGGGATACTATGTATAAATTAAAAGAAGCTAAACTAGCTAGCCAAAAGGCAAAATTTGAAGATGTGGAAAC
TAGAAACACAGTGACCAAGA

Product: CutA1 divalent ion tolerance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MSRSMFYITAESMEDAEQLAKQLVEDRLVACVNVIPKIKSFFYWEGEAQSEEEVLLFGKTKTETVSKLVERVKELHPYDV
PCVVTWEMKDGNPDFLKWIDDEVNQC

Sequences:

>Translated_106_residues
MSRSMFYITAESMEDAEQLAKQLVEDRLVACVNVIPKIKSFFYWEGEAQSEEEVLLFGKTKTETVSKLVERVKELHPYDV
PCVVTWEMKDGNPDFLKWIDDEVNQC
>Mature_105_residues
SRSMFYITAESMEDAEQLAKQLVEDRLVACVNVIPKIKSFFYWEGEAQSEEEVLLFGKTKTETVSKLVERVKELHPYDVP
CVVTWEMKDGNPDFLKWIDDEVNQC

Specific function: Involved in resistance toward heavy metals [H]

COG id: COG1324

COG function: function code P; Uncharacterized protein involved in tolerance to divalent cations

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutA family [H]

Homologues:

Organism=Homo sapiens, GI62526024, Length=98, Percent_Identity=36.734693877551, Blast_Score=80, Evalue=3e-16,
Organism=Homo sapiens, GI62526022, Length=98, Percent_Identity=36.734693877551, Blast_Score=80, Evalue=3e-16,
Organism=Homo sapiens, GI7706244, Length=98, Percent_Identity=36.734693877551, Blast_Score=80, Evalue=3e-16,
Organism=Homo sapiens, GI62526026, Length=98, Percent_Identity=36.734693877551, Blast_Score=80, Evalue=3e-16,
Organism=Homo sapiens, GI62198241, Length=98, Percent_Identity=36.734693877551, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790579, Length=92, Percent_Identity=33.695652173913, Blast_Score=69, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI32565476, Length=99, Percent_Identity=38.3838383838384, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641937, Length=102, Percent_Identity=37.2549019607843, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004323
- InterPro:   IPR011322 [H]

Pfam domain/function: PF03091 CutA1 [H]

EC number: NA

Molecular weight: Translated: 12354; Mature: 12223

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSMFYITAESMEDAEQLAKQLVEDRLVACVNVIPKIKSFFYWEGEAQSEEEVLLFGKT
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEECCC
KTETVSKLVERVKELHPYDVPCVVTWEMKDGNPDFLKWIDDEVNQC
CHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRSMFYITAESMEDAEQLAKQLVEDRLVACVNVIPKIKSFFYWEGEAQSEEEVLLFGKT
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEECCC
KTETVSKLVERVKELHPYDVPCVVTWEMKDGNPDFLKWIDDEVNQC
CHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA