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The map label for this gene is coaE [H]

Identifier: 188586503

GI number: 188586503

Start: 1980659

End: 1981249

Strand: Reverse

Name: coaE [H]

Synonym: Nther_1889

Alternate gene names: 188586503

Gene position: 1981249-1980659 (Counterclockwise)

Preceding gene: 188586504

Following gene: 188586502

Centisome position: 62.59

GC content: 35.36

Gene sequence:

>591_bases
ATGATTGTAGGATTAACCGGTGGTATTGCTTCAGGAAAATCTACAGTTATGCAAATACTTTCAGAATTAGGTGCCGCAAC
TATAGACGCAGATAAAATATCTAAAGAACTTACTGAAAAGGATTCTCCGGTTTTAGATGAAATATGTCAGGCGTTTGGCC
ATGAATACTTTACGGAAGAAGGCTGTCTCAATCGGGCAAAACTTGGGGAAAAAGTTTTTAGCGATAAGCAGGCAAAGCAA
AAATTAGAGGCTATTTTGCATCCTAAAATTAACGAAAGATTGAAACAAGAGATTTCTAAATTTCAGGCTGAAAACCAGAA
TAAACTCGTAGTAGTTGAAATAGCTTTGCTATTTGAAACAGGTCAAGAAAAGCAATATGATGAAAGTTGGGTAATATGGG
TAGATTATCACACACAATTAAAAAGGTTAAAGGAACGTAATGGACTTACAACTCAACAAGCTCGTGATAGGATAAATGCT
CAAATGTCATTGGATAAAAAGAAGCAATTAGCCCATCGAGTAATAGATAATTCTGGCACTTTTGAAGAGACAGAATTGCA
GGTCAAGCAGATTTATTCAAAATTGCTATAG

Upstream 100 bases:

>100_bases
GAATCTGTTTAATCAAATATTTTACAGTATCTATAACTATATATTTATCAGCGCCTAAGATTAAGAAAACAATAATACTA
CAGTGAAAAGGATGATTATT

Downstream 100 bases:

>100_bases
TAAATCGAGATAGTTTGTAATACAATATGAACAGAAATCGATATTAGAGGTGTCTTTAATAATGAATTTGCAAAATTCAC
GTAAAAGATATTTAATTGCG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MIVGLTGGIASGKSTVMQILSELGAATIDADKISKELTEKDSPVLDEICQAFGHEYFTEEGCLNRAKLGEKVFSDKQAKQ
KLEAILHPKINERLKQEISKFQAENQNKLVVVEIALLFETGQEKQYDESWVIWVDYHTQLKRLKERNGLTTQQARDRINA
QMSLDKKKQLAHRVIDNSGTFEETELQVKQIYSKLL

Sequences:

>Translated_196_residues
MIVGLTGGIASGKSTVMQILSELGAATIDADKISKELTEKDSPVLDEICQAFGHEYFTEEGCLNRAKLGEKVFSDKQAKQ
KLEAILHPKINERLKQEISKFQAENQNKLVVVEIALLFETGQEKQYDESWVIWVDYHTQLKRLKERNGLTTQQARDRINA
QMSLDKKKQLAHRVIDNSGTFEETELQVKQIYSKLL
>Mature_196_residues
MIVGLTGGIASGKSTVMQILSELGAATIDADKISKELTEKDSPVLDEICQAFGHEYFTEEGCLNRAKLGEKVFSDKQAKQ
KLEAILHPKINERLKQEISKFQAENQNKLVVVEIALLFETGQEKQYDESWVIWVDYHTQLKRLKERNGLTTQQARDRINA
QMSLDKKKQLAHRVIDNSGTFEETELQVKQIYSKLL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=196, Percent_Identity=39.2857142857143, Blast_Score=145, Evalue=2e-35,
Organism=Homo sapiens, GI191252795, Length=196, Percent_Identity=39.2857142857143, Blast_Score=145, Evalue=2e-35,
Organism=Homo sapiens, GI205277394, Length=194, Percent_Identity=29.8969072164948, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI110227607, Length=194, Percent_Identity=29.8969072164948, Blast_Score=100, Evalue=7e-22,
Organism=Homo sapiens, GI110227605, Length=194, Percent_Identity=29.8969072164948, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI110227603, Length=194, Percent_Identity=29.8969072164948, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI110227601, Length=194, Percent_Identity=29.8969072164948, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1786292, Length=195, Percent_Identity=33.3333333333333, Blast_Score=106, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17554944, Length=198, Percent_Identity=34.8484848484849, Blast_Score=133, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI25143409, Length=196, Percent_Identity=32.6530612244898, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6320402, Length=200, Percent_Identity=33.5, Blast_Score=99, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24644728, Length=194, Percent_Identity=39.1752577319588, Blast_Score=140, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24658602, Length=195, Percent_Identity=30.2564102564103, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22309; Mature: 22309

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGLTGGIASGKSTVMQILSELGAATIDADKISKELTEKDSPVLDEICQAFGHEYFTEE
CEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHH
GCLNRAKLGEKVFSDKQAKQKLEAILHPKINERLKQEISKFQAENQNKLVVVEIALLFET
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHC
GQEKQYDESWVIWVDYHTQLKRLKERNGLTTQQARDRINAQMSLDKKKQLAHRVIDNSGT
CCCCCCCCCEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FEETELQVKQIYSKLL
CHHHHHHHHHHHHHHC
>Mature Secondary Structure
MIVGLTGGIASGKSTVMQILSELGAATIDADKISKELTEKDSPVLDEICQAFGHEYFTEE
CEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHH
GCLNRAKLGEKVFSDKQAKQKLEAILHPKINERLKQEISKFQAENQNKLVVVEIALLFET
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHC
GQEKQYDESWVIWVDYHTQLKRLKERNGLTTQQARDRINAQMSLDKKKQLAHRVIDNSGT
CCCCCCCCCEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FEETELQVKQIYSKLL
CHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA