BacMap

Definition	Natranaerobius thermophilus JW/NM-WN-LF, complete genome.
Accession	NC_010718
Length	3,165,557

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The map label for this gene is crt [H]

Identifier: 188586492

GI number: 188586492

Start: 1964993

End: 1965781

Strand: Reverse

Name: crt [H]

Synonym: Nther_1877

Alternate gene names: 188586492

Gene position: 1965781-1964993 (Counterclockwise)

Preceding gene: 188586493

Following gene: 188586491

Centisome position: 62.1

GC content: 34.47

Gene sequence:

>789_bases
ATGACTTCTGAAAAACTAATTTTAAAAGAAATGAAAAACGATTCTGTTGCCCTATTGAAGATTAATCGTCCCAAAGCATT
AAATGCCTTGAATGTCGAAGTCTTGAAGGAACTATACAATGAATTACAAGAGATTGAAAAAGATGAGACTGTTAAATGTG
TAATTATCACGGGTAGTGGTGAAAAAGCTTTCGTAGGAGGCGCGGATATAGGGTCAATGAAAGATATGGATACTGTTGAA
GCGAGAAAGTTCTCTGAATTTGGAAACGAAGTCATGACCTACATTGAAAATTTAAAAATTCCAGTTATAGCTGCAATAAA
TGGTTATGCTCTTGGTGGAGGTTTAGAACTTGCTTTATCTGCTGATATTAGAATTGCTTCTGAAAACGCTAAATTTGGAA
CCCCAGAAATTAACTTAGGGATTTTTCCTGGTTTTGGAGGTACCCAAAGGCTTCCCAAAATTGTAGGACTACATAAAGCT
AAAGAACTTATTTTTACCGGTGAAATAATTACAGCGGAAGACGCCAAGGAAGCAAACTTAATTAATAAGGTGGTAAAACA
AGAAGAACTGATGGAAGTTGTTACTAAAATGGCATCAAAGATAGCTTCAAAAAGTAGTATACCTCTTAAGTTAGCTAAAC
AAGTTATAAATAGAGGTTATGAAGAACCCATTGAGACTGGTTCCTTGATGGAAACTAGCTCTTTTAGTGTATGTTTTTCA
ACTGAGGACCAGAAAGAAGGAATGGAAGCATTTTTAGAAAATAGGAAACCAACTTTTAAAGATAAATAA

Upstream 100 bases:

>100_bases
TATTTAGCAAGTTTAGTCATATTTCAAAATTATGAGAATAGTCTGAATTTGAATCTGTTTAAAACAGAACTCAAATTTAA
GGAGTTAAGGAGGGTTTTTA

Downstream 100 bases:

>100_bases
GAAGGGAGGAAATTATTATGAACAAGGCTTTAGTAGTAGGTGCTGGTACTATGGGTTCTGGAATAGCCCAAGTTTTAGCA
ACAGCTGGTTGTGAAGTATT

Product: short chain enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MTSEKLILKEMKNDSVALLKINRPKALNALNVEVLKELYNELQEIEKDETVKCVIITGSGEKAFVGGADIGSMKDMDTVE
ARKFSEFGNEVMTYIENLKIPVIAAINGYALGGGLELALSADIRIASENAKFGTPEINLGIFPGFGGTQRLPKIVGLHKA
KELIFTGEIITAEDAKEANLINKVVKQEELMEVVTKMASKIASKSSIPLKLAKQVINRGYEEPIETGSLMETSSFSVCFS
TEDQKEGMEAFLENRKPTFKDK

Sequences:

>Translated_262_residues
MTSEKLILKEMKNDSVALLKINRPKALNALNVEVLKELYNELQEIEKDETVKCVIITGSGEKAFVGGADIGSMKDMDTVE
ARKFSEFGNEVMTYIENLKIPVIAAINGYALGGGLELALSADIRIASENAKFGTPEINLGIFPGFGGTQRLPKIVGLHKA
KELIFTGEIITAEDAKEANLINKVVKQEELMEVVTKMASKIASKSSIPLKLAKQVINRGYEEPIETGSLMETSSFSVCFS
TEDQKEGMEAFLENRKPTFKDK
>Mature_261_residues
TSEKLILKEMKNDSVALLKINRPKALNALNVEVLKELYNELQEIEKDETVKCVIITGSGEKAFVGGADIGSMKDMDTVEA
RKFSEFGNEVMTYIENLKIPVIAAINGYALGGGLELALSADIRIASENAKFGTPEINLGIFPGFGGTQRLPKIVGLHKAK
ELIFTGEIITAEDAKEANLINKVVKQEELMEVVTKMASKIASKSSIPLKLAKQVINRGYEEPIETGSLMETSSFSVCFST
EDQKEGMEAFLENRKPTFKDK

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=254, Percent_Identity=44.4881889763779, Blast_Score=210, Evalue=1e-54,
Organism=Homo sapiens, GI4502327, Length=255, Percent_Identity=36.8627450980392, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI31542718, Length=253, Percent_Identity=31.2252964426877, Blast_Score=127, Evalue=7e-30,
Organism=Homo sapiens, GI20127408, Length=174, Percent_Identity=37.9310344827586, Blast_Score=121, Evalue=6e-28,
Organism=Homo sapiens, GI68989263, Length=220, Percent_Identity=33.1818181818182, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI150378541, Length=246, Percent_Identity=30.4878048780488, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI70995211, Length=254, Percent_Identity=28.740157480315, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI37594469, Length=182, Percent_Identity=30.2197802197802, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI37594471, Length=182, Percent_Identity=30.2197802197802, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI4757968, Length=233, Percent_Identity=27.4678111587983, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI49355787, Length=233, Percent_Identity=27.4678111587983, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI62530384, Length=259, Percent_Identity=23.9382239382239, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI25453481, Length=233, Percent_Identity=27.0386266094421, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI51538573, Length=233, Percent_Identity=27.0386266094421, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI116235487, Length=193, Percent_Identity=28.4974093264249, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI260274832, Length=216, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI261878539, Length=123, Percent_Identity=35.7723577235772, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI45643119, Length=216, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI260275230, Length=216, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4757966, Length=231, Percent_Identity=26.8398268398268, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI51538581, Length=231, Percent_Identity=26.8398268398268, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI221136756, Length=233, Percent_Identity=27.0386266094421, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI221136753, Length=233, Percent_Identity=27.0386266094421, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI221307494, Length=194, Percent_Identity=30.4123711340206, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI157694516, Length=178, Percent_Identity=24.7191011235955, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI213417737, Length=178, Percent_Identity=24.7191011235955, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI295842266, Length=257, Percent_Identity=21.7898832684825, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787659, Length=251, Percent_Identity=40.2390438247012, Blast_Score=197, Evalue=8e-52,
Organism=Escherichia coli, GI221142681, Length=264, Percent_Identity=35.6060606060606, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1790281, Length=228, Percent_Identity=32.8947368421053, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1788682, Length=210, Percent_Identity=33.8095238095238, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787660, Length=251, Percent_Identity=34.2629482071713, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1788597, Length=259, Percent_Identity=29.7297297297297, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082183, Length=254, Percent_Identity=29.1338582677165, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17554946, Length=249, Percent_Identity=42.570281124498, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI25145438, Length=246, Percent_Identity=41.869918699187, Blast_Score=193, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI17540714, Length=225, Percent_Identity=38.6666666666667, Blast_Score=157, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17534483, Length=269, Percent_Identity=30.4832713754647, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17536985, Length=260, Percent_Identity=29.2307692307692, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17558304, Length=216, Percent_Identity=34.2592592592593, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17560910, Length=208, Percent_Identity=32.2115384615385, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17508953, Length=216, Percent_Identity=36.1111111111111, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25144276, Length=216, Percent_Identity=36.1111111111111, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17508951, Length=216, Percent_Identity=36.1111111111111, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25144157, Length=189, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI25144160, Length=189, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17540306, Length=268, Percent_Identity=27.9850746268657, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17549921, Length=219, Percent_Identity=27.8538812785388, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25141363, Length=170, Percent_Identity=30.5882352941176, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17535521, Length=242, Percent_Identity=24.7933884297521, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320241, Length=190, Percent_Identity=33.1578947368421, Blast_Score=107, Evalue=1e-24,
Organism=Drosophila melanogaster, GI20129971, Length=247, Percent_Identity=44.1295546558704, Blast_Score=201, Evalue=4e-52,
Organism=Drosophila melanogaster, GI24653477, Length=247, Percent_Identity=44.1295546558704, Blast_Score=201, Evalue=4e-52,
Organism=Drosophila melanogaster, GI24653139, Length=249, Percent_Identity=37.7510040160643, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI19922422, Length=267, Percent_Identity=27.3408239700375, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI28571730, Length=156, Percent_Identity=37.1794871794872, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28571729, Length=156, Percent_Identity=37.1794871794872, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI21357171, Length=252, Percent_Identity=27.7777777777778, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24654903, Length=206, Percent_Identity=29.6116504854369, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19921000, Length=176, Percent_Identity=36.9318181818182, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24583077, Length=176, Percent_Identity=36.9318181818182, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24583079, Length=176, Percent_Identity=36.9318181818182, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19920382, Length=256, Percent_Identity=26.5625, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24650670, Length=196, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24583165, Length=257, Percent_Identity=26.0700389105058, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI19921018, Length=215, Percent_Identity=31.1627906976744, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 28741; Mature: 28609

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSEKLILKEMKNDSVALLKINRPKALNALNVEVLKELYNELQEIEKDETVKCVIITGSG
CCCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
EKAFVGGADIGSMKDMDTVEARKFSEFGNEVMTYIENLKIPVIAAINGYALGGGLELALS
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEECCCEEEEEE
ADIRIASENAKFGTPEINLGIFPGFGGTQRLPKIVGLHKAKELIFTGEIITAEDAKEANL
CCEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHEEEECCEEECCCCHHHHH
INKVVKQEELMEVVTKMASKIASKSSIPLKLAKQVINRGYEEPIETGSLMETSSFSVCFS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCEEEEC
TEDQKEGMEAFLENRKPTFKDK
CCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TSEKLILKEMKNDSVALLKINRPKALNALNVEVLKELYNELQEIEKDETVKCVIITGSG
CCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
EKAFVGGADIGSMKDMDTVEARKFSEFGNEVMTYIENLKIPVIAAINGYALGGGLELALS
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEECCCEEEEEE
ADIRIASENAKFGTPEINLGIFPGFGGTQRLPKIVGLHKAKELIFTGEIITAEDAKEANL
CCEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHEEEECCEEECCCCHHHHH
INKVVKQEELMEVVTKMASKIASKSSIPLKLAKQVINRGYEEPIETGSLMETSSFSVCFS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCEEEEC
TEDQKEGMEAFLENRKPTFKDK
CCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]