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The map label for this gene is yqeV [H]

Identifier: 188586422

GI number: 188586422

Start: 1870498

End: 1871853

Strand: Reverse

Name: yqeV [H]

Synonym: Nther_1807

Alternate gene names: 188586422

Gene position: 1871853-1870498 (Counterclockwise)

Preceding gene: 188586423

Following gene: 188586421

Centisome position: 59.13

GC content: 35.4

Gene sequence:

>1356_bases
ATGATTATAGGTGAAAAAAATAAATCATTTAAAATCATAACTTTAGGATGTCCTCTTAACCAGTCAGAAAGTGATTTAAT
GAGAGCCAGACTTCATCAAGCTGGGTATAGTGAAACTGGAACTGGAGATGATACTGCCGATATATATATTATTAATTCCT
GTACCGTTACCCAAAATGCTGCAAGAAAGTCAAGAAAAGAAGCCAGAAAAGCAAAAAAGGGAAATCCAGATGCCTGGGTT
TGTTTAGTCGGTTGTTATGGTGAGATGGAATACGAAGAAATTAAAGAAAAAATACCTGAAATAGATTTAATTATAGGTAC
GCGAAATCGAGAAAAAGCTATTGAAAAACTAGTTGGCCAGGAATTAGATTTAAATCAATTTCATAATTTTCCCCAAGATA
ATAATGAAATAAGACCTGATAAAATTAGGCCTGCTATAAAAATACAAGAAGGTTGTGACCAATCATGTAGTTACTGTATA
GTTACTCTGGCGCGTGGTCGTCCCAAGAGTAGAGAGTTTCGACAAATCAAACAACAGGTAAAATCTTATCTGGAAGAGGG
CTATCAAGAGATTATATTAGCTGGAACAAATATGGGCTTATATGGTAAAGATGTGAAAGGTCAATCAAAGCACTCTTATA
AATTTATAGATTTGCCCATGCTTGTTTCTGAGCTGGCTACATTACCTTATGACGATTATAGGATTAGGATAAGTTCTTTA
GAACCTTTGGAAATGACTGAGGAACTTTTATATGCCATGAAAGAACACGACAAAATTTGTAATTATCTGTACTTGCCTCT
TCAGAGTGGCAGTGATAGAATACTTAAACTAATGAACAGAAAGTATACTACCGATGATTTTGCCAGGATAGTGGAAAAGG
CCAAGACATTACTTCCCGGCGTGGGCATCATGACAGATTTGATAGTTGGTTTTCCTGGAGAGAAGGAAGAAGATCATAAA
GCTACCATGGAATTTGTAGAAGAATTGAAGTTAAGCAAGCTACATGTTTTTCCCTATTCACCTCGCCCTAAAACACTAGC
TGCAAGCTTTAATGTTCAGGTTCGTCCTGATATCAAAAGAGCGAGGACTGAAGAAATGAAAGAGTTGGGTCAAAAACTTG
CTAGAAGATTTTATCAGGAAAACTTAAATACCAGGTTGCGGGTTTTGTATGAGCGAAATTATGAAACATCTGATAAAATT
TTGGGTGAAGGTTTTTCGGAAAACTATTGTTTGGTTAGATTTGAAACAAAGGGTACTAATCTAACTAATAAAAAAGGTGA
ATTTGTAAACGTAATAAGCCATCAAAATTATGATTGGGGATTGATGGGTTCAACAAGTCAGGAGGTGAAATATTGA

Upstream 100 bases:

>100_bases
CTTAAAGAAAACTTAATTGCTTAAACACCTGTTTTTTTGTATAATGCCTTCAGGATTTAAAAAATAAAAAACATAAGAAC
CTAGTGGAGGAAGGCTCAAA

Downstream 100 bases:

>100_bases
TCTCTCAAGATTTAATAAATAGAATTAATGAGCTATACAAGAAACAAAAAGAATCAGGTTTAACTGATGAAGAACAACAA
GAACAGCAAAAATTAAGACA

Product: RNA modification enzyme, MiaB family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MIIGEKNKSFKIITLGCPLNQSESDLMRARLHQAGYSETGTGDDTADIYIINSCTVTQNAARKSRKEARKAKKGNPDAWV
CLVGCYGEMEYEEIKEKIPEIDLIIGTRNREKAIEKLVGQELDLNQFHNFPQDNNEIRPDKIRPAIKIQEGCDQSCSYCI
VTLARGRPKSREFRQIKQQVKSYLEEGYQEIILAGTNMGLYGKDVKGQSKHSYKFIDLPMLVSELATLPYDDYRIRISSL
EPLEMTEELLYAMKEHDKICNYLYLPLQSGSDRILKLMNRKYTTDDFARIVEKAKTLLPGVGIMTDLIVGFPGEKEEDHK
ATMEFVEELKLSKLHVFPYSPRPKTLAASFNVQVRPDIKRARTEEMKELGQKLARRFYQENLNTRLRVLYERNYETSDKI
LGEGFSENYCLVRFETKGTNLTNKKGEFVNVISHQNYDWGLMGSTSQEVKY

Sequences:

>Translated_451_residues
MIIGEKNKSFKIITLGCPLNQSESDLMRARLHQAGYSETGTGDDTADIYIINSCTVTQNAARKSRKEARKAKKGNPDAWV
CLVGCYGEMEYEEIKEKIPEIDLIIGTRNREKAIEKLVGQELDLNQFHNFPQDNNEIRPDKIRPAIKIQEGCDQSCSYCI
VTLARGRPKSREFRQIKQQVKSYLEEGYQEIILAGTNMGLYGKDVKGQSKHSYKFIDLPMLVSELATLPYDDYRIRISSL
EPLEMTEELLYAMKEHDKICNYLYLPLQSGSDRILKLMNRKYTTDDFARIVEKAKTLLPGVGIMTDLIVGFPGEKEEDHK
ATMEFVEELKLSKLHVFPYSPRPKTLAASFNVQVRPDIKRARTEEMKELGQKLARRFYQENLNTRLRVLYERNYETSDKI
LGEGFSENYCLVRFETKGTNLTNKKGEFVNVISHQNYDWGLMGSTSQEVKY
>Mature_451_residues
MIIGEKNKSFKIITLGCPLNQSESDLMRARLHQAGYSETGTGDDTADIYIINSCTVTQNAARKSRKEARKAKKGNPDAWV
CLVGCYGEMEYEEIKEKIPEIDLIIGTRNREKAIEKLVGQELDLNQFHNFPQDNNEIRPDKIRPAIKIQEGCDQSCSYCI
VTLARGRPKSREFRQIKQQVKSYLEEGYQEIILAGTNMGLYGKDVKGQSKHSYKFIDLPMLVSELATLPYDDYRIRISSL
EPLEMTEELLYAMKEHDKICNYLYLPLQSGSDRILKLMNRKYTTDDFARIVEKAKTLLPGVGIMTDLIVGFPGEKEEDHK
ATMEFVEELKLSKLHVFPYSPRPKTLAASFNVQVRPDIKRARTEEMKELGQKLARRFYQENLNTRLRVLYERNYETSDKI
LGEGFSENYCLVRFETKGTNLTNKKGEFVNVISHQNYDWGLMGSTSQEVKY

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=415, Percent_Identity=29.1566265060241, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI28872784, Length=422, Percent_Identity=27.2511848341232, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI28872782, Length=422, Percent_Identity=27.2511848341232, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI1786882, Length=443, Percent_Identity=29.5711060948081, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI1787057, Length=383, Percent_Identity=28.7206266318538, Blast_Score=152, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17553146, Length=413, Percent_Identity=26.634382566586, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI71996771, Length=340, Percent_Identity=27.3529411764706, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356207, Length=419, Percent_Identity=25.7756563245823, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI19922432, Length=389, Percent_Identity=28.0205655526992, Blast_Score=147, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 51906; Mature: 51906

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGEKNKSFKIITLGCPLNQSESDLMRARLHQAGYSETGTGDDTADIYIINSCTVTQNA
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCEECHHH
ARKSRKEARKAKKGNPDAWVCLVGCYGEMEYEEIKEKIPEIDLIIGTRNREKAIEKLVGQ
HHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHCC
ELDLNQFHNFPQDNNEIRPDKIRPAIKIQEGCDQSCSYCIVTLARGRPKSREFRQIKQQV
CCCHHHHCCCCCCCCCCCHHHCCCCEEECCCCCCCCCEEEEEHHCCCCCCHHHHHHHHHH
KSYLEEGYQEIILAGTNMGLYGKDVKGQSKHSYKFIDLPMLVSELATLPYDDYRIRISSL
HHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCEEEEECCC
EPLEMTEELLYAMKEHDKICNYLYLPLQSGSDRILKLMNRKYTTDDFARIVEKAKTLLPG
CHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
VGIMTDLIVGFPGEKEEDHKATMEFVEELKLSKLHVFPYSPRPKTLAASFNVQVRPDIKR
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCCCEEEEEEEEEECCCHHH
ARTEEMKELGQKLARRFYQENLNTRLRVLYERNYETSDKILGEGFSENYCLVRFETKGTN
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHCCCCCCCEEEEEEECCCCC
LTNKKGEFVNVISHQNYDWGLMGSTSQEVKY
CCCCCCCEEEEECCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MIIGEKNKSFKIITLGCPLNQSESDLMRARLHQAGYSETGTGDDTADIYIINSCTVTQNA
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCEECHHH
ARKSRKEARKAKKGNPDAWVCLVGCYGEMEYEEIKEKIPEIDLIIGTRNREKAIEKLVGQ
HHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHCC
ELDLNQFHNFPQDNNEIRPDKIRPAIKIQEGCDQSCSYCIVTLARGRPKSREFRQIKQQV
CCCHHHHCCCCCCCCCCCHHHCCCCEEECCCCCCCCCEEEEEHHCCCCCCHHHHHHHHHH
KSYLEEGYQEIILAGTNMGLYGKDVKGQSKHSYKFIDLPMLVSELATLPYDDYRIRISSL
HHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCEEEEECCC
EPLEMTEELLYAMKEHDKICNYLYLPLQSGSDRILKLMNRKYTTDDFARIVEKAKTLLPG
CHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
VGIMTDLIVGFPGEKEEDHKATMEFVEELKLSKLHVFPYSPRPKTLAASFNVQVRPDIKR
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCCCEEEEEEEEEECCCHHH
ARTEEMKELGQKLARRFYQENLNTRLRVLYERNYETSDKILGEGFSENYCLVRFETKGTN
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHCCCCCCCEEEEEEECCCCC
LTNKKGEFVNVISHQNYDWGLMGSTSQEVKY
CCCCCCCEEEEECCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9023197; 9384377 [H]