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The map label for this gene is soxB [H]

Identifier: 188586368

GI number: 188586368

Start: 1818360

End: 1819508

Strand: Reverse

Name: soxB [H]

Synonym: Nther_1751

Alternate gene names: 188586368

Gene position: 1819508-1818360 (Counterclockwise)

Preceding gene: 188586369

Following gene: 188586367

Centisome position: 57.48

GC content: 38.21

Gene sequence:

>1149_bases
ATGATTAATAACACGGCGAATGTAGTGATTATTGGAGGAGGTATCAATGGATTAGCTACAGCTTATAACCTGGCCAAAAT
GGGAGAAAGCGATATAGTTTTAGTTGAGCGAGAATATATTGCAAGTGGAGCTACCGGTAGGTGTGGAGCAGGAATAAGGC
AGCAATGGGGAACTGAAAAAAACTGTATTTTAAGTAGGGAAAGTGTCAGGATGTTTGAAAACTTAGAAGAAACTTTAGAT
TACGACCACGATATAGAATTTAAACAAAAGGGTTATTTGTTTTTGGCTTATGATGAAGGGCTTTTTGAACAATTTAAGAA
AAATGTGAAACTGCAAAATGATCTTAATATTCCCTCTAGACTGTTAACTCCTGGTGAAATTAAAGATATAGCCCCTCATG
TAAATATAAATGGTCTATATGGTGGGACCATTTGTGAGGAAGATGGGCATGCCAATCCTTTTCATGTTAGTGAAGCCTAT
CGAAAAGCGGCAGAGAGATTAGGAGTGAAAATTTACACCTATACAGAAGTATGGGATATTGAAACAGAAAGAGGTGAAGT
AACTGGTGTAATTACAGATAAAGGAAAAATATCAACGAAAAAGGTGTTAAATACCGCCGGGGGTCATGCTAAAGAAGTTG
GACGAATGGCAGGGATTGAACTTCCTATATATCCCGAGCGACATGAAGCCATGGTTTCGGAACCGCTAGATCCTTTTCAA
GGTCCTATGATCGTTTCGCTTTATCATGATTTTTACATGCAGCAGGTACCTCATGGAAGTTTTCTCATGGGGCATGGTGA
CCCCGAAGAACCAGAAAGTTTGAACATTAATTCTAGTGTTAAATTTCCTATTAAATTATCCAAAAAGATTGCCAGTGTAT
TCCCGCCGTTAAAGGATATTAAAATCATACGGCAATGGGCTGGATTATATGATATGAGTCCAGATGCACAACCGATTTTG
GGTGAAACCTCAGTTAAAGGTTTTTATACTTCTGCAGGTTATAGCGGGCACGGTTTCATGATTGCACCTTATACATCAAA
ATTAGTTGCCCAGCTTATCCTTGAACAAGAGCCAGAACTCGATATTAGTATGTTAAATTACGATCGCTTTGAAAGAGGAG
AATTAATTTTAGAACCATCGGTAGTTTGA

Upstream 100 bases:

>100_bases
GTAAAAGTTAAAGGTAGCTCTATATCTGAGGAAACTACCGGTGTTTATCGACCTTTATTAAAACCTGTCAAGCTGGGAAC
TTTAGCAAGGGGTGATCTCG

Downstream 100 bases:

>100_bases
TTTTTGACTTTTTGTTGATCTACTATTAGTCAAAGGGTTTTTTAGGAATAAAGTCGAATTAAATAATTAGAGACACTCAA
TTTTATAGGAGGTGTAGTAA

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MINNTANVVIIGGGINGLATAYNLAKMGESDIVLVEREYIASGATGRCGAGIRQQWGTEKNCILSRESVRMFENLEETLD
YDHDIEFKQKGYLFLAYDEGLFEQFKKNVKLQNDLNIPSRLLTPGEIKDIAPHVNINGLYGGTICEEDGHANPFHVSEAY
RKAAERLGVKIYTYTEVWDIETERGEVTGVITDKGKISTKKVLNTAGGHAKEVGRMAGIELPIYPERHEAMVSEPLDPFQ
GPMIVSLYHDFYMQQVPHGSFLMGHGDPEEPESLNINSSVKFPIKLSKKIASVFPPLKDIKIIRQWAGLYDMSPDAQPIL
GETSVKGFYTSAGYSGHGFMIAPYTSKLVAQLILEQEPELDISMLNYDRFERGELILEPSVV

Sequences:

>Translated_382_residues
MINNTANVVIIGGGINGLATAYNLAKMGESDIVLVEREYIASGATGRCGAGIRQQWGTEKNCILSRESVRMFENLEETLD
YDHDIEFKQKGYLFLAYDEGLFEQFKKNVKLQNDLNIPSRLLTPGEIKDIAPHVNINGLYGGTICEEDGHANPFHVSEAY
RKAAERLGVKIYTYTEVWDIETERGEVTGVITDKGKISTKKVLNTAGGHAKEVGRMAGIELPIYPERHEAMVSEPLDPFQ
GPMIVSLYHDFYMQQVPHGSFLMGHGDPEEPESLNINSSVKFPIKLSKKIASVFPPLKDIKIIRQWAGLYDMSPDAQPIL
GETSVKGFYTSAGYSGHGFMIAPYTSKLVAQLILEQEPELDISMLNYDRFERGELILEPSVV
>Mature_382_residues
MINNTANVVIIGGGINGLATAYNLAKMGESDIVLVEREYIASGATGRCGAGIRQQWGTEKNCILSRESVRMFENLEETLD
YDHDIEFKQKGYLFLAYDEGLFEQFKKNVKLQNDLNIPSRLLTPGEIKDIAPHVNINGLYGGTICEEDGHANPFHVSEAY
RKAAERLGVKIYTYTEVWDIETERGEVTGVITDKGKISTKKVLNTAGGHAKEVGRMAGIELPIYPERHEAMVSEPLDPFQ
GPMIVSLYHDFYMQQVPHGSFLMGHGDPEEPESLNINSSVKFPIKLSKKIASVFPPLKDIKIIRQWAGLYDMSPDAQPIL
GETSVKGFYTSAGYSGHGFMIAPYTSKLVAQLILEQEPELDISMLNYDRFERGELILEPSVV

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=388, Percent_Identity=29.3814432989691, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI21361378, Length=388, Percent_Identity=29.3814432989691, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI194306651, Length=384, Percent_Identity=27.6041666666667, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI24797151, Length=391, Percent_Identity=25.8312020460358, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI8923708, Length=417, Percent_Identity=24.9400479616307, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI60499001, Length=384, Percent_Identity=22.9166666666667, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1787559, Length=385, Percent_Identity=23.8961038961039, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787438, Length=423, Percent_Identity=20.0945626477541, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71994045, Length=398, Percent_Identity=23.6180904522613, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994052, Length=402, Percent_Identity=22.8855721393035, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17541536, Length=433, Percent_Identity=22.6327944572748, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20130091, Length=396, Percent_Identity=26.2626262626263, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI20129729, Length=382, Percent_Identity=26.9633507853403, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571104, Length=391, Percent_Identity=24.5524296675192, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17985989, Length=379, Percent_Identity=23.4828496042216, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 42526; Mature: 42526

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINNTANVVIIGGGINGLATAYNLAKMGESDIVLVEREYIASGATGRCGAGIRQQWGTEK
CCCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCCCCCCHHHHCCCCC
NCILSRESVRMFENLEETLDYDHDIEFKQKGYLFLAYDEGLFEQFKKNVKLQNDLNIPSR
CEEECHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCHH
LLTPGEIKDIAPHVNINGLYGGTICEEDGHANPFHVSEAYRKAAERLGVKIYTYTEVWDI
HCCCCCHHHCCCCCEECEEECCEEECCCCCCCCCCHHHHHHHHHHHCCEEEEEEEEEEEE
ETERGEVTGVITDKGKISTKKVLNTAGGHAKEVGRMAGIELPIYPERHEAMVSEPLDPFQ
ECCCCEEEEEEECCCCCCHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCC
GPMIVSLYHDFYMQQVPHGSFLMGHGDPEEPESLNINSSVKFPIKLSKKIASVFPPLKDI
CCEEEEHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCEEECHHHHHHHHHHCCCHHHH
KIIRQWAGLYDMSPDAQPILGETSVKGFYTSAGYSGHGFMIAPYTSKLVAQLILEQEPEL
HHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEECCHHHHHHHHHHHCCCCCC
DISMLNYDRFERGELILEPSVV
CEEEECCCCCCCCCEEECCCCC
>Mature Secondary Structure
MINNTANVVIIGGGINGLATAYNLAKMGESDIVLVEREYIASGATGRCGAGIRQQWGTEK
CCCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCCCCCCHHHHCCCCC
NCILSRESVRMFENLEETLDYDHDIEFKQKGYLFLAYDEGLFEQFKKNVKLQNDLNIPSR
CEEECHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCHH
LLTPGEIKDIAPHVNINGLYGGTICEEDGHANPFHVSEAYRKAAERLGVKIYTYTEVWDI
HCCCCCHHHCCCCCEECEEECCEEECCCCCCCCCCHHHHHHHHHHHCCEEEEEEEEEEEE
ETERGEVTGVITDKGKISTKKVLNTAGGHAKEVGRMAGIELPIYPERHEAMVSEPLDPFQ
ECCCCEEEEEEECCCCCCHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCC
GPMIVSLYHDFYMQQVPHGSFLMGHGDPEEPESLNINSSVKFPIKLSKKIASVFPPLKDI
CCEEEEHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCEEECHHHHHHHHHHCCCHHHH
KIIRQWAGLYDMSPDAQPILGETSVKGFYTSAGYSGHGFMIAPYTSKLVAQLILEQEPEL
HHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEECCHHHHHHHHHHHCCCCCC
DISMLNYDRFERGELILEPSVV
CEEEECCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]