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The map label for this gene is gpsA [H]

Identifier: 188586245

GI number: 188586245

Start: 1708760

End: 1709806

Strand: Reverse

Name: gpsA [H]

Synonym: Nther_1628

Alternate gene names: 188586245

Gene position: 1709806-1708760 (Counterclockwise)

Preceding gene: 188586246

Following gene: 188586242

Centisome position: 54.01

GC content: 36.77

Gene sequence:

>1047_bases
GTGTCTGTGTTTAGGGAAAGAATTGGAGTTATTGGTTCAGGAAGTTGGGGTACGGCCTTATCTATCTTATTAGCAAAAAA
TAATCACTCAGTAACTTTGTGGACTAGACGTGAAGAATTGTGTGAAACTCTTACAGCTACTAGGGAAAACAAAGAGTATT
TACCGAATATAAAGCTTCCTGAAAATATACAAGTGACTTATGAACTTGAACAAGCTGTAAAAGATAAACAAGTTTTAATT
TTTGTAGTTCCGACCCATGCAATGCGCGAGACTGCTGAACAAGTTAAACAGTTTCTAGAAGATGATACCTTGATAATAAG
CGCCTCTAAAGGGTTTGAGATCGAAACTTTACATACCATGAGTCAAGTTTTAGCAGATACTTTATTTAAAGGAGATAATT
CTAGAATTGCAGTTTTATCAGGTCCAAATCATGCTGAAGAAGTCAGCAAAGAAATACCATCAGCTACTGTGATCGCATCA
AAAAAACGCTCTGTGGCTGAAAAATTACAAGGTATTTTTATGAGTTCTAGATTTAGAGTTTATACAAATCCCGATGTCAT
TGGAGTGGAAATGGGAGGAGCTCTAAAAAATATTATGGCTTTAGGTTCAGGAATTTCCGATGGGCTTGGTTTCGGGGATA
ACACTAAAGCTGCTTTTATGACTAGAGGGATTTACGAAATATCGCGGTTGGGAATAACTCAAGGTGCACGTCCTATGACT
TTTGCGGGTTTATCTGGTATCGGTGATTTAATAGTTACATGTACAAGTGATCATTCACGTAATCGAAGAGCAGGAAAGCT
TTTGGGAAGTGGTAAAAAACTAGAAGACATCCTAGCAACTACTAATATGGTAGTTGAAGGTGTGAAGACTACAAAAGCCG
CTTATTATTTGGCTGAGAAAACAGGTACTGAAATGCCTATTACCAAAGAAATTTATAATATCCTTTTTCACGATAAGTCT
CCTGAATATGGAGTTAGCAGTTTGATGGAAAGAGTGAGAACTAATGAAATGGAAGAAGTAGTTGATTGGGAATTATGGGA
AGAGTAA

Upstream 100 bases:

>100_bases
TCAGACATATACCTAATATCAAAAGGTTATTAGCAGGAACTGAACGTAAGCTTAATGAAAAAGAGAATGCAAATGTTCGA
GAAAATGGGGGTGAGTAGTT

Downstream 100 bases:

>100_bases
TCTAAAGTGTAGAGTTTTAGAGTTAGACATTAAAAAGCCCATCTCTTTGAGATGGGCTTTTTGTAATTAATATTCTTCAT
CGTCTTCAAAGTATTCACTT

Product: Glycerol-3-phosphate dehydrogenase (NAD(P)(+))

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSVFRERIGVIGSGSWGTALSILLAKNNHSVTLWTRREELCETLTATRENKEYLPNIKLPENIQVTYELEQAVKDKQVLI
FVVPTHAMRETAEQVKQFLEDDTLIISASKGFEIETLHTMSQVLADTLFKGDNSRIAVLSGPNHAEEVSKEIPSATVIAS
KKRSVAEKLQGIFMSSRFRVYTNPDVIGVEMGGALKNIMALGSGISDGLGFGDNTKAAFMTRGIYEISRLGITQGARPMT
FAGLSGIGDLIVTCTSDHSRNRRAGKLLGSGKKLEDILATTNMVVEGVKTTKAAYYLAEKTGTEMPITKEIYNILFHDKS
PEYGVSSLMERVRTNEMEEVVDWELWEE

Sequences:

>Translated_348_residues
MSVFRERIGVIGSGSWGTALSILLAKNNHSVTLWTRREELCETLTATRENKEYLPNIKLPENIQVTYELEQAVKDKQVLI
FVVPTHAMRETAEQVKQFLEDDTLIISASKGFEIETLHTMSQVLADTLFKGDNSRIAVLSGPNHAEEVSKEIPSATVIAS
KKRSVAEKLQGIFMSSRFRVYTNPDVIGVEMGGALKNIMALGSGISDGLGFGDNTKAAFMTRGIYEISRLGITQGARPMT
FAGLSGIGDLIVTCTSDHSRNRRAGKLLGSGKKLEDILATTNMVVEGVKTTKAAYYLAEKTGTEMPITKEIYNILFHDKS
PEYGVSSLMERVRTNEMEEVVDWELWEE
>Mature_347_residues
SVFRERIGVIGSGSWGTALSILLAKNNHSVTLWTRREELCETLTATRENKEYLPNIKLPENIQVTYELEQAVKDKQVLIF
VVPTHAMRETAEQVKQFLEDDTLIISASKGFEIETLHTMSQVLADTLFKGDNSRIAVLSGPNHAEEVSKEIPSATVIASK
KRSVAEKLQGIFMSSRFRVYTNPDVIGVEMGGALKNIMALGSGISDGLGFGDNTKAAFMTRGIYEISRLGITQGARPMTF
AGLSGIGDLIVTCTSDHSRNRRAGKLLGSGKKLEDILATTNMVVEGVKTTKAAYYLAEKTGTEMPITKEIYNILFHDKSP
EYGVSSLMERVRTNEMEEVVDWELWEE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=333, Percent_Identity=30.9309309309309, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI24307999, Length=344, Percent_Identity=29.0697674418605, Blast_Score=142, Evalue=6e-34,
Organism=Escherichia coli, GI1790037, Length=328, Percent_Identity=42.0731707317073, Blast_Score=283, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI32564399, Length=347, Percent_Identity=29.3948126801153, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI193210136, Length=356, Percent_Identity=28.3707865168539, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI32564403, Length=356, Percent_Identity=28.3707865168539, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17507425, Length=357, Percent_Identity=26.3305322128852, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI193210134, Length=344, Percent_Identity=27.3255813953488, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320181, Length=360, Percent_Identity=28.8888888888889, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6324513, Length=344, Percent_Identity=28.1976744186047, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17136202, Length=350, Percent_Identity=30.5714285714286, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI17136204, Length=350, Percent_Identity=30.5714285714286, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI17136200, Length=350, Percent_Identity=30.5714285714286, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI22026922, Length=346, Percent_Identity=26.878612716763, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI45551945, Length=290, Percent_Identity=25.8620689655172, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281362270, Length=290, Percent_Identity=25.8620689655172, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24648969, Length=246, Percent_Identity=26.4227642276423, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 38491; Mature: 38359

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFRERIGVIGSGSWGTALSILLAKNNHSVTLWTRREELCETLTATRENKEYLPNIKLP
CCCHHHHCCEEECCCHHHEEEEEEECCCCEEEEEECHHHHHHHHHHCCCCHHHCCCCCCC
ENIQVTYELEQAVKDKQVLIFVVPTHAMRETAEQVKQFLEDDTLIISASKGFEIETLHTM
CCCEEEEEHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHHHH
SQVLADTLFKGDNSRIAVLSGPNHAEEVSKEIPSATVIASKKRSVAEKLQGIFMSSRFRV
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCEEE
YTNPDVIGVEMGGALKNIMALGSGISDGLGFGDNTKAAFMTRGIYEISRLGITQGARPMT
EECCCEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEE
FAGLSGIGDLIVTCTSDHSRNRRAGKLLGSGKKLEDILATTNMVVEGVKTTKAAYYLAEK
ECCCCCCCCEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHEEEECC
TGTEMPITKEIYNILFHDKSPEYGVSSLMERVRTNEMEEVVDWELWEE
CCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCC
>Mature Secondary Structure 
SVFRERIGVIGSGSWGTALSILLAKNNHSVTLWTRREELCETLTATRENKEYLPNIKLP
CCHHHHCCEEECCCHHHEEEEEEECCCCEEEEEECHHHHHHHHHHCCCCHHHCCCCCCC
ENIQVTYELEQAVKDKQVLIFVVPTHAMRETAEQVKQFLEDDTLIISASKGFEIETLHTM
CCCEEEEEHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHHHH
SQVLADTLFKGDNSRIAVLSGPNHAEEVSKEIPSATVIASKKRSVAEKLQGIFMSSRFRV
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCEEE
YTNPDVIGVEMGGALKNIMALGSGISDGLGFGDNTKAAFMTRGIYEISRLGITQGARPMT
EECCCEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEE
FAGLSGIGDLIVTCTSDHSRNRRAGKLLGSGKKLEDILATTNMVVEGVKTTKAAYYLAEK
ECCCCCCCCEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHEEEECC
TGTEMPITKEIYNILFHDKSPEYGVSSLMERVRTNEMEEVVDWELWEE
CCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA