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The map label for this gene is galE [H]

Identifier: 188586191

GI number: 188586191

Start: 1653866

End: 1654852

Strand: Reverse

Name: galE [H]

Synonym: Nther_1573

Alternate gene names: 188586191

Gene position: 1654852-1653866 (Counterclockwise)

Preceding gene: 188586198

Following gene: 188586188

Centisome position: 52.28

GC content: 33.23

Gene sequence:

>987_bases
ATGATACTGGTGACTGGAGGAGCGGGTTATATAGGGAGTCATATGGTAAAGTCTCTTCTTGATCAAAGTTATGAAGTCAT
TGTGTTAGATAATCTTTCTACAGGTCATAAATCGGCAGTTGATCAGAGAGCAGTCTTTATAAAAGGGGATGTAATCGAAG
AAGACAAATTAGATGAAATTTTTGAGCGCTATTCTATTGAATGTGTCATGCATTTTGCCGCTAATTGTTATGTTGGTGAA
TCTATCATTAAACCACTAAAATATTATAAAAATAATGTTAATTCCTCTATTTGTTTATTAAATAAGATGTTAGAACATAA
GGTTACTAAAATTGTGTTTTCATCATCATGTGCAACATACGGAACACCTAATGTAGAAAAGATAGACGAAAGCTGTCACA
CCAATCCTATAAATCCTTATGGTAGATCGAAATTAATGACAGAACAGATTGTAAAAGATATATCCAAAGCACATCAATTT
GACTTTATTTTTTTACGTTATTTTAATGTGGCTGGAGCAGATCCTTCTGGTAAAATTGGAGAACATCATGATCCAGAAAC
TCATTTAATACCAAATATCTTACTCCATCTATTAGGGAAAAAAGATAGGATAGTCATTCATGGGGATAATTACCCCACAG
AAGATGGTACTTGCATAAGGGATTTCATCCATATAAGTGATTTAGTTGAAGCTCATCTTCTATCACTTGAAAGCTTAATT
AATAATAATCACAGAAATGAAATTTACAATGTTGGAAGTAATCACGGCTATTCAATCAAAGAAGTGATAAAAATGTGCGA
AGAAGTTACCGGTAAACAAGTTAATGTTGTACATGGTGATAGAAGAGAAGGGGATCCACCTAAACTGGTTGCTTCTAATC
AAAAAATATATCGTCATTTGGGATGGAAACCCAAATATCCTTTACGGGATATAATAAAGACGGCCTGGAACTGGCATTTT
AATAATCCTAATGGCTATCAAGGATAA

Upstream 100 bases:

>100_bases
AATTGATTACATATTTGTGAATATTTATCAAACAAAGAATTTAGTAATTTAGATTGGTTTAAAAGTTATTCAAAAGACCA
GGAGGGGGGAGCAGATCAGT

Downstream 100 bases:

>100_bases
ATAAATTCCTGTTTATCTTTAATCCTCTCTTTTTAAGATAACTGATAGCATAGTCTCTATGGGCAAAATCATTGAGAATT
ATCACTCCAGTTAACTGTTT

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MILVTGGAGYIGSHMVKSLLDQSYEVIVLDNLSTGHKSAVDQRAVFIKGDVIEEDKLDEIFERYSIECVMHFAANCYVGE
SIIKPLKYYKNNVNSSICLLNKMLEHKVTKIVFSSSCATYGTPNVEKIDESCHTNPINPYGRSKLMTEQIVKDISKAHQF
DFIFLRYFNVAGADPSGKIGEHHDPETHLIPNILLHLLGKKDRIVIHGDNYPTEDGTCIRDFIHISDLVEAHLLSLESLI
NNNHRNEIYNVGSNHGYSIKEVIKMCEEVTGKQVNVVHGDRREGDPPKLVASNQKIYRHLGWKPKYPLRDIIKTAWNWHF
NNPNGYQG

Sequences:

>Translated_328_residues
MILVTGGAGYIGSHMVKSLLDQSYEVIVLDNLSTGHKSAVDQRAVFIKGDVIEEDKLDEIFERYSIECVMHFAANCYVGE
SIIKPLKYYKNNVNSSICLLNKMLEHKVTKIVFSSSCATYGTPNVEKIDESCHTNPINPYGRSKLMTEQIVKDISKAHQF
DFIFLRYFNVAGADPSGKIGEHHDPETHLIPNILLHLLGKKDRIVIHGDNYPTEDGTCIRDFIHISDLVEAHLLSLESLI
NNNHRNEIYNVGSNHGYSIKEVIKMCEEVTGKQVNVVHGDRREGDPPKLVASNQKIYRHLGWKPKYPLRDIIKTAWNWHF
NNPNGYQG
>Mature_328_residues
MILVTGGAGYIGSHMVKSLLDQSYEVIVLDNLSTGHKSAVDQRAVFIKGDVIEEDKLDEIFERYSIECVMHFAANCYVGE
SIIKPLKYYKNNVNSSICLLNKMLEHKVTKIVFSSSCATYGTPNVEKIDESCHTNPINPYGRSKLMTEQIVKDISKAHQF
DFIFLRYFNVAGADPSGKIGEHHDPETHLIPNILLHLLGKKDRIVIHGDNYPTEDGTCIRDFIHISDLVEAHLLSLESLI
NNNHRNEIYNVGSNHGYSIKEVIKMCEEVTGKQVNVVHGDRREGDPPKLVASNQKIYRHLGWKPKYPLRDIIKTAWNWHF
NNPNGYQG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=343, Percent_Identity=36.4431486880466, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI56118217, Length=343, Percent_Identity=36.4431486880466, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI189083684, Length=343, Percent_Identity=36.4431486880466, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI7657641, Length=336, Percent_Identity=30.3571428571429, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI42516563, Length=320, Percent_Identity=25.625, Blast_Score=99, Evalue=4e-21,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=39.7626112759644, Blast_Score=250, Evalue=9e-68,
Organism=Escherichia coli, GI48994969, Length=358, Percent_Identity=25.4189944134078, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788353, Length=355, Percent_Identity=25.6338028169014, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790049, Length=266, Percent_Identity=30.4511278195489, Blast_Score=88, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=36.5217391304348, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=36.3112391930836, Blast_Score=222, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17539532, Length=320, Percent_Identity=25.9375, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17568069, Length=344, Percent_Identity=23.546511627907, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI115532424, Length=333, Percent_Identity=20.7207207207207, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=346, Percent_Identity=37.8612716763006, Blast_Score=226, Evalue=5e-60,
Organism=Drosophila melanogaster, GI19923002, Length=342, Percent_Identity=37.719298245614, Blast_Score=234, Evalue=7e-62,
Organism=Drosophila melanogaster, GI21356223, Length=312, Percent_Identity=26.9230769230769, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37203; Mature: 37203

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVTGGAGYIGSHMVKSLLDQSYEVIVLDNLSTGHKSAVDQRAVFIKGDVIEEDKLDEI
CEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHCEEEEECCCCCHHHHHHH
FERYSIECVMHFAANCYVGESIIKPLKYYKNNVNSSICLLNKMLEHKVTKIVFSSSCATY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GTPNVEKIDESCHTNPINPYGRSKLMTEQIVKDISKAHQFDFIFLRYFNVAGADPSGKIG
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEHHHCCCCCCCCCC
EHHDPETHLIPNILLHLLGKKDRIVIHGDNYPTEDGTCIRDFIHISDLVEAHLLSLESLI
CCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
NNNHRNEIYNVGSNHGYSIKEVIKMCEEVTGKQVNVVHGDRREGDPPKLVASNQKIYRHL
CCCCCHHHEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCHHHHHHC
GWKPKYPLRDIIKTAWNWHFNNPNGYQG
CCCCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MILVTGGAGYIGSHMVKSLLDQSYEVIVLDNLSTGHKSAVDQRAVFIKGDVIEEDKLDEI
CEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHCEEEEECCCCCHHHHHHH
FERYSIECVMHFAANCYVGESIIKPLKYYKNNVNSSICLLNKMLEHKVTKIVFSSSCATY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GTPNVEKIDESCHTNPINPYGRSKLMTEQIVKDISKAHQFDFIFLRYFNVAGADPSGKIG
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEHHHCCCCCCCCCC
EHHDPETHLIPNILLHLLGKKDRIVIHGDNYPTEDGTCIRDFIHISDLVEAHLLSLESLI
CCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
NNNHRNEIYNVGSNHGYSIKEVIKMCEEVTGKQVNVVHGDRREGDPPKLVASNQKIYRHL
CCCCCHHHEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCHHHHHHC
GWKPKYPLRDIIKTAWNWHFNNPNGYQG
CCCCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]