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The map label for this gene is nirA [H]

Identifier: 188585721

GI number: 188585721

Start: 1155041

End: 1157431

Strand: Direct

Name: nirA [H]

Synonym: Nther_1094

Alternate gene names: 188585721

Gene position: 1155041-1157431 (Clockwise)

Preceding gene: 188585720

Following gene: 188585722

Centisome position: 36.49

GC content: 34.5

Gene sequence:

>2391_bases
TTGCAACTCAATGTACCGGAAGAAATTATTCGAGATTTAAAAAGTTATCAGGATAAAGTTATGGATTTTCAGAAAGGTGA
CTTGGATGAGTTCAGGTTTAAACCGTACCGGGTTGGGAGGGGAGTTTACGAACAGAGAAATGGTAAATATATGATTAGAA
CTAGATTGCCCGGGGGAGAACTAACTTTAGAACAACTAAAAGTTATCAAGAAATTGGCTGAAGCATACGCAGAAAATTTA
ATACATTTAACAACCAGACAGGATATCCAGTTTCACAATGTGGAGCTTTCTGATTCACCTAAAATTATAGAGGAACTATT
ACAATGGGGTATCTTGACTAAGGGTTCCGGGGGAAACACACCAAGAAATGTGGTGGGTTCGCCTTTGTCTGGAGTATCTA
AGGATGAAGTATTTGATATTAGACCTTTTGTCAAATATACAACGGATTATTTGTTACAAGATGAAAGTGCTTTCAATTTA
CCAAGAAAATTTAAAATTGCTTTTTCTAATTCTCTGGCTGATACTGCTAACGCTACCATTTCTGATTTGGGTTTTATAGC
TAAAATCAAAGATGGCCAAAAAGGTTTTGAAGTATATGGAGCTGGTGGTTTGGGAAATGAACCTTCTAAAGCGATTAAGT
TATTTAATTTTATAACCGAGGATCAAATCTTATTTCATGTAGAAACTATGAAAGAGTTATTTCAGCAGAAGGGAGATAGA
CTTAACAAAAACAAAGCACGAATCAGACATATAATGTCTAGGCTTGGACAAGATCAATTTAAAGAGCTATATTATAAATT
ATTAAAACAAATCAAGGCTGATCATCCGGAGTTGTCTTTATGGGATAAAATTTCAAATCATCTAGATATAAATGATGAGA
ATAAAGATAGTTTTGATAATTTTCAAATAGACAGTCAAGGACAAGCGTACCGAGAAAACAGGTATTCCGAAATTTCCAAT
CAAAGGAAGATACAGCGGTTATCAATAGAACAAAAACAGGCCGGAGCCTATTCGGTCTATTTTCATCCCGAAAAAGGCGA
CTTAAACACTAGGGATTTACAATTATTAATAACAACCATAGAACAAATGAATGATAATATATCGTTTCGAATTTCTAATA
CCCAGGGTTTTTATCTATGTAATTTGTCCTTTTCAGAAGGTGAATTACTCATTAATAAACTTGATTATCTTATTCCGGAA
TACCAGGTAGAGTGCTCAGTTTCGTGTCCAGGAGCTGCTACCTGTAAACTAGGTCTTTGTTTATCTCAAAAAATGTTAAT
TCAAACTCTAGATGAATTAAAGCAAAGTGATACTGAAGCACTTAAAGAACTTCCTCGGCTATACATTTCTGGTTGTCCTA
ATTCATGTGGCCAGCATCAAATTGGCCTACTAGGTTTATCCGGAAAAGCTAGTAGGACAGAGGACGGACTTGTACCTGCT
TATACAGTGTATATGGGAGGTAAAACCGAGGCAAACAAAGGACGATTGGCTACGGAATTTGGTGAAATACCAGCTCAAAA
GGTTCCTGTATTTTTAAAAGAACTGGCTAAATTAAAAGCTCAAAATGGATATAAAGATTTTGAAGAATTTGTTTATAATT
CAAATAAAAAAATTACCCAACTTATTACAGTTTTTTCAACTTTAGAAAGTTATCAAGAAAATCCCGGTTTATATTTTGAT
TTCGGGTCTAACAAACAATTTTCCCTTGAAGGTAGGGGTCCTGGTGAATGCGGTGCTGGAGTGCTAGACATAATCAAAAT
AGATATCAACAACGCCGAAAGCAGGTTACAAGACTATCAAAACCTAGTTGATACCCGGTTATTGTACCAGGCAGCTTTAT
CGGGAGCTAGGGCTTTATTGGTTTTAAAAGGTATCGATACCAATAAAGATAGAGAAATTTTTAATGAATTTATTAAACAC
TTTGTAGATACGGGCTATGTTCGAGATAGTGTAATAGATTTAGTAAATAATTTAATGGATTTTAAAATGGGAGACTTGTC
AGACTTGAGTTCTTATTATGATGAAGTAATTTATCTTGTTCAAAGAGTTAAAGAGATTTTTCAATCTCTTAACTCTAGGT
TAGAAATTACCGCAGCTAAAGTAGCAAATGAATCAGAGCAACAGACTCAGAAGAGTACAAATAGTGGTGAAGAATCACAA
GGCGAAGAAAGTGATGTGGTGGATTTAAGAGGTGTTAAATGCCCTATGAATTTTGTAAAGGTGAAAATGGCTCTGTCATC
TCTTCAAAATGGCGAAATACAAGCTTTTTATCTTGACAATGGTGAACCCATGGATAATGTACCTCAAAGTGTTAGGGATG
AAGGACATTTCATAAAGGATATAGTTAAGTATAGTGACTATAGCAAAATATTAATTAAAAAGTCTGATTAG

Upstream 100 bases:

>100_bases
AGAATTTAAAAAATGCAAGCCAAGAACTAAATGTTCAATTACTTGTAAGTAAAGATCAAGTTATCAATTCAAATACAACA
GATGAAGGAGGGTTGTAAAG

Downstream 100 bases:

>100_bases
ACCAATTTTTATGGAGGGATTCAAATGGATATCAATTTGAATGGGAAAAAAAGACGATTTGAACAAACGAGATTGTCAGT
AACGGATTTAGTCAAAGAAT

Product: Ferredoxin--nitrite reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 796; Mature: 796

Protein sequence:

>796_residues
MQLNVPEEIIRDLKSYQDKVMDFQKGDLDEFRFKPYRVGRGVYEQRNGKYMIRTRLPGGELTLEQLKVIKKLAEAYAENL
IHLTTRQDIQFHNVELSDSPKIIEELLQWGILTKGSGGNTPRNVVGSPLSGVSKDEVFDIRPFVKYTTDYLLQDESAFNL
PRKFKIAFSNSLADTANATISDLGFIAKIKDGQKGFEVYGAGGLGNEPSKAIKLFNFITEDQILFHVETMKELFQQKGDR
LNKNKARIRHIMSRLGQDQFKELYYKLLKQIKADHPELSLWDKISNHLDINDENKDSFDNFQIDSQGQAYRENRYSEISN
QRKIQRLSIEQKQAGAYSVYFHPEKGDLNTRDLQLLITTIEQMNDNISFRISNTQGFYLCNLSFSEGELLINKLDYLIPE
YQVECSVSCPGAATCKLGLCLSQKMLIQTLDELKQSDTEALKELPRLYISGCPNSCGQHQIGLLGLSGKASRTEDGLVPA
YTVYMGGKTEANKGRLATEFGEIPAQKVPVFLKELAKLKAQNGYKDFEEFVYNSNKKITQLITVFSTLESYQENPGLYFD
FGSNKQFSLEGRGPGECGAGVLDIIKIDINNAESRLQDYQNLVDTRLLYQAALSGARALLVLKGIDTNKDREIFNEFIKH
FVDTGYVRDSVIDLVNNLMDFKMGDLSDLSSYYDEVIYLVQRVKEIFQSLNSRLEITAAKVANESEQQTQKSTNSGEESQ
GEESDVVDLRGVKCPMNFVKVKMALSSLQNGEIQAFYLDNGEPMDNVPQSVRDEGHFIKDIVKYSDYSKILIKKSD

Sequences:

>Translated_796_residues
MQLNVPEEIIRDLKSYQDKVMDFQKGDLDEFRFKPYRVGRGVYEQRNGKYMIRTRLPGGELTLEQLKVIKKLAEAYAENL
IHLTTRQDIQFHNVELSDSPKIIEELLQWGILTKGSGGNTPRNVVGSPLSGVSKDEVFDIRPFVKYTTDYLLQDESAFNL
PRKFKIAFSNSLADTANATISDLGFIAKIKDGQKGFEVYGAGGLGNEPSKAIKLFNFITEDQILFHVETMKELFQQKGDR
LNKNKARIRHIMSRLGQDQFKELYYKLLKQIKADHPELSLWDKISNHLDINDENKDSFDNFQIDSQGQAYRENRYSEISN
QRKIQRLSIEQKQAGAYSVYFHPEKGDLNTRDLQLLITTIEQMNDNISFRISNTQGFYLCNLSFSEGELLINKLDYLIPE
YQVECSVSCPGAATCKLGLCLSQKMLIQTLDELKQSDTEALKELPRLYISGCPNSCGQHQIGLLGLSGKASRTEDGLVPA
YTVYMGGKTEANKGRLATEFGEIPAQKVPVFLKELAKLKAQNGYKDFEEFVYNSNKKITQLITVFSTLESYQENPGLYFD
FGSNKQFSLEGRGPGECGAGVLDIIKIDINNAESRLQDYQNLVDTRLLYQAALSGARALLVLKGIDTNKDREIFNEFIKH
FVDTGYVRDSVIDLVNNLMDFKMGDLSDLSSYYDEVIYLVQRVKEIFQSLNSRLEITAAKVANESEQQTQKSTNSGEESQ
GEESDVVDLRGVKCPMNFVKVKMALSSLQNGEIQAFYLDNGEPMDNVPQSVRDEGHFIKDIVKYSDYSKILIKKSD
>Mature_796_residues
MQLNVPEEIIRDLKSYQDKVMDFQKGDLDEFRFKPYRVGRGVYEQRNGKYMIRTRLPGGELTLEQLKVIKKLAEAYAENL
IHLTTRQDIQFHNVELSDSPKIIEELLQWGILTKGSGGNTPRNVVGSPLSGVSKDEVFDIRPFVKYTTDYLLQDESAFNL
PRKFKIAFSNSLADTANATISDLGFIAKIKDGQKGFEVYGAGGLGNEPSKAIKLFNFITEDQILFHVETMKELFQQKGDR
LNKNKARIRHIMSRLGQDQFKELYYKLLKQIKADHPELSLWDKISNHLDINDENKDSFDNFQIDSQGQAYRENRYSEISN
QRKIQRLSIEQKQAGAYSVYFHPEKGDLNTRDLQLLITTIEQMNDNISFRISNTQGFYLCNLSFSEGELLINKLDYLIPE
YQVECSVSCPGAATCKLGLCLSQKMLIQTLDELKQSDTEALKELPRLYISGCPNSCGQHQIGLLGLSGKASRTEDGLVPA
YTVYMGGKTEANKGRLATEFGEIPAQKVPVFLKELAKLKAQNGYKDFEEFVYNSNKKITQLITVFSTLESYQENPGLYFD
FGSNKQFSLEGRGPGECGAGVLDIIKIDINNAESRLQDYQNLVDTRLLYQAALSGARALLVLKGIDTNKDREIFNEFIKH
FVDTGYVRDSVIDLVNNLMDFKMGDLSDLSSYYDEVIYLVQRVKEIFQSLNSRLEITAAKVANESEQQTQKSTNSGEESQ
GEESDVVDLRGVKCPMNFVKVKMALSSLQNGEIQAFYLDNGEPMDNVPQSVRDEGHFIKDIVKYSDYSKILIKKSD

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

None

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.7.7.1 [H]

Molecular weight: Translated: 90298; Mature: 90298

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNVPEEIIRDLKSYQDKVMDFQKGDLDEFRFKPYRVGRGVYEQRNGKYMIRTRLPGGE
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHCCCHHHCCCCCEEEEEECCCCC
LTLEQLKVIKKLAEAYAENLIHLTTRQDIQFHNVELSDSPKIIEELLQWGILTKGSGGNT
CCHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEEECCCCHHHHHHHHHCCCEECCCCCCC
PRNVVGSPLSGVSKDEVFDIRPFVKYTTDYLLQDESAFNLPRKFKIAFSNSLADTANATI
CHHHCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHCCCHH
SDLGFIAKIKDGQKGFEVYGAGGLGNEPSKAIKLFNFITEDQILFHVETMKELFQQKGDR
HHCCEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCHHEEEHHHHHHHHHHHCCC
LNKNKARIRHIMSRLGQDQFKELYYKLLKQIKADHPELSLWDKISNHLDINDENKDSFDN
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCC
FQIDSQGQAYRENRYSEISNQRKIQRLSIEQKQAGAYSVYFHPEKGDLNTRDLQLLITTI
EEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHH
EQMNDNISFRISNTQGFYLCNLSFSEGELLINKLDYLIPEYQVECSVSCPGAATCKLGLC
HHCCCCEEEEEECCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
LSQKMLIQTLDELKQSDTEALKELPRLYISGCPNSCGQHQIGLLGLSGKASRTEDGLVPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCE
YTVYMGGKTEANKGRLATEFGEIPAQKVPVFLKELAKLKAQNGYKDFEEFVYNSNKKITQ
EEEEECCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHH
LITVFSTLESYQENPGLYFDFGSNKQFSLEGRGPGECGAGVLDIIKIDINNAESRLQDYQ
HHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCCCEEEEEEEECCCHHHHHHHHH
NLVDTRLLYQAALSGARALLVLKGIDTNKDREIFNEFIKHFVDTGYVRDSVIDLVNNLMD
HHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FKMGDLSDLSSYYDEVIYLVQRVKEIFQSLNSRLEITAAKVANESEQQTQKSTNSGEESQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCHHHHHHHHCCCCCCCC
GEESDVVDLRGVKCPMNFVKVKMALSSLQNGEIQAFYLDNGEPMDNVPQSVRDEGHFIKD
CCCCCCEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHCCHHHHHCCHHHHH
IVKYSDYSKILIKKSD
HHHHCCCCEEEEEECC
>Mature Secondary Structure
MQLNVPEEIIRDLKSYQDKVMDFQKGDLDEFRFKPYRVGRGVYEQRNGKYMIRTRLPGGE
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHCCCHHHCCCCCEEEEEECCCCC
LTLEQLKVIKKLAEAYAENLIHLTTRQDIQFHNVELSDSPKIIEELLQWGILTKGSGGNT
CCHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEEECCCCHHHHHHHHHCCCEECCCCCCC
PRNVVGSPLSGVSKDEVFDIRPFVKYTTDYLLQDESAFNLPRKFKIAFSNSLADTANATI
CHHHCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHCCCHH
SDLGFIAKIKDGQKGFEVYGAGGLGNEPSKAIKLFNFITEDQILFHVETMKELFQQKGDR
HHCCEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCHHEEEHHHHHHHHHHHCCC
LNKNKARIRHIMSRLGQDQFKELYYKLLKQIKADHPELSLWDKISNHLDINDENKDSFDN
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCC
FQIDSQGQAYRENRYSEISNQRKIQRLSIEQKQAGAYSVYFHPEKGDLNTRDLQLLITTI
EEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHH
EQMNDNISFRISNTQGFYLCNLSFSEGELLINKLDYLIPEYQVECSVSCPGAATCKLGLC
HHCCCCEEEEEECCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
LSQKMLIQTLDELKQSDTEALKELPRLYISGCPNSCGQHQIGLLGLSGKASRTEDGLVPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCE
YTVYMGGKTEANKGRLATEFGEIPAQKVPVFLKELAKLKAQNGYKDFEEFVYNSNKKITQ
EEEEECCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHH
LITVFSTLESYQENPGLYFDFGSNKQFSLEGRGPGECGAGVLDIIKIDINNAESRLQDYQ
HHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCCCEEEEEEEECCCHHHHHHHHH
NLVDTRLLYQAALSGARALLVLKGIDTNKDREIFNEFIKHFVDTGYVRDSVIDLVNNLMD
HHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FKMGDLSDLSSYYDEVIYLVQRVKEIFQSLNSRLEITAAKVANESEQQTQKSTNSGEESQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCHHHHHHHHCCCCCCCC
GEESDVVDLRGVKCPMNFVKVKMALSSLQNGEIQAFYLDNGEPMDNVPQSVRDEGHFIKD
CCCCCCEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHCCHHHHHCCHHHHH
IVKYSDYSKILIKKSD
HHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8490140 [H]